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can a tumor make you anemic

by Dr. Emilie Cassin MD Published 2 years ago Updated 2 years ago
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The cancers most closely associated with anemia are: Cancers that involve the bone marrow. Blood cancers like leukemia, lymphoma, and myeloma interfere with or destroy the marrow's ability to make healthy blood cells. Other cancers that spread to the bone marrow can also cause anemia.Mar 24, 2010

Can cancer cause anemia?

Causes of anemia which are related to cancer (either due to cancer itself or due to treatments for cancer include: Bone marrow replacement: Some cancers, such as lymphomas or metastases from breast cancer can invade the bone marrow and replace the bone marrow cells which make red blood cells.

Can chemotherapy cause anemia?

Certain chemotherapy drugs, such as platinum-based chemotherapy, can cause anemia. You are also more likely to develop anemia if you have a specific type of tumor, such as in the lungs or ovaries, or if you already had a low hemoglobin count prior to having cancer. 10

How do tumors cause iron deficiency anemia?

As the tumor grows, the vessel bursts, leading to the loss of red blood cells. The bleeding, in turn, can give rise to an iron deficiency. Even if there are ample supplies of iron in the blood, the surrounding inflammation can cause iron molecules to become "trapped" in immune cells.

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Can a tumor cause anemia?

Anemia and colon cancer These cells can form tumors on or inside blood vessels in the colon that carry red blood cells. Decades of research, including this 2018 study , suggests that these tumors can lead to bleeding and a loss of healthy red blood cells, common causes of anemia.

What kind of cancer causes low iron?

In a study published in July 2013 in the Annals of Oncology, iron deficiency was most commonly seen in people with pancreatic cancer (present in 63 percent of participants), followed by colorectal cancer (52 percent) and lung cancer (51 percent).

Is anemia an effect of cancer?

Cancer treatments, such as chemotherapy and radiation therapy, as well as cancers that affect the bone marrow, can cause anemia. When you are anemic, your body does not have enough red blood cells. Red blood cells are the cells that that carry oxygen from the lungs throughout your body to help it work properly.

Can a benign tumor cause anemia?

Anemia of chronic disease can result from chronic inflammation caused by ongoing infections, tissue damage, various forms of arthritis, benign or malignant tumors, or a variety of chronic medical conditions.

Is low iron a symptom of pancreatic cancer?

Chronic diseases like pancreatic cancer, or inflammation like pancreatitis, can cause anemia. And chemotherapy or radiation therapy can also cause or worsen anemia. If you or a loved one is experiencing new or worsening fatigue or muscle weakness, these could be symptoms of anemia.

Can low iron indicate colon cancer?

Conclusions: Males referred with iron deficiency anemia have a significant risk of having colon cancer. The risk seems lower in females; this gender difference has been observed in other studies and further evidence should be sought before advising any change in referral practice.

What are the 3 main causes of anemia?

Anemia has three main causes: blood loss, lack of red blood cell production, and high rates of red blood cell destruction. Conditions that may lead to anemia include: Heavy periods. Pregnancy.

What level of anemia is fatal?

Severe: Hemoglobin 6.5 to 7.9 g/dL[1] Life-threatening: Hemoglobin less than 6.5 g/dL.

What disease causes low iron?

Some of the most common causes of iron deficiency anaemia are outlined below.Monthly periods. In women of reproductive age, periods are the most common cause of iron deficiency anaemia. ... Pregnancy. ... Gastrointestinal blood loss. ... Non-steroidal anti-inflammatory drugs. ... Chronic kidney disease. ... Other causes.

Is being anemic serious?

In many cases, it's mild, but anemia can also be serious and life-threatening. Anemia can happen because: Your body doesn't make enough red blood cells. Bleeding causes you to lose red blood cells more quickly than they can be replaced.

Can anemia turn into leukemia?

Anemia and leukemia are both conditions that affect the blood. Moreover, people with the latter have an increased risk of developing anemia. However, anemia cannot cause leukemia, and these conditions remain different in several important respects.

Is anemia a symptom of leukemia?

What Are the Symptoms of Leukemia? Many types of leukemia produce no obvious symptoms in the early stages. Eventually, symptoms may include any of the following: Anemia and related symptoms, such as fatigue, pallor, and a general feeling of illness.

At what stage does colon cancer cause anemia?

Anemia correlated with the T stage of the tumor: 21% of patients diagnosed at stages 0–1 had anemia, 39% at stage 2, 44% at stage 3, and 66% at stage 4 (p=0.001).

Is anemia a symptom of leukemia?

What Are the Symptoms of Leukemia? Many types of leukemia produce no obvious symptoms in the early stages. Eventually, symptoms may include any of the following: Anemia and related symptoms, such as fatigue, pallor, and a general feeling of illness.

Can low iron lead to leukemia?

Anemia and leukemia are both conditions that affect the blood. Moreover, people with the latter have an increased risk of developing anemia. However, anemia cannot cause leukemia, and these conditions remain different in several important respects.

Why do my iron levels keep dropping?

Heavy periods and pregnancy are very common causes of iron deficiency anaemia. Heavy periods can be treated with medicine. For men and for women whose periods have stopped, bleeding in the stomach and intestines is the most common cause of iron deficiency anaemia.

What cancers affect the bone marrow?

Cancers involving the bone marrow. Blood cancers such as leukemia, multiple myeloma, and lymphoma inhibit or destroy the bone marrow’s production of healthy blood cells. Other cancers that metastasize or spread to the bone marrow can also cause anemia.

Does anemia interfere with cancer?

Even if your anemia does not conflict or interfere with cancer treatment, getting it under control will help replenish your energy levels and improve your overall quality of life.

Is chemotherapy anemia?

According to the National Anemia Action Council, almost all patients receiving chemotherapy drugs for cancer are mildly anemic. Moreover, as much as 80 percent develop a more serious health issue. The form of chemotherapy you’re receiving, your cancer stage, and your overall health play a significant role in whether you will or will not have anemia.

Can cancer make you feel tired?

If you have cancer and find yourself feeling tired, short of breath, and lightheaded, you may also be anemic . Anemia is a common side effect of certain cancer treatments, and in some cases, cancer itself can cause anemia.

Can radiation cause anemia?

Aside from chemotherapy drugs, radiation therapy to certain areas of the body may damage the bone marrow and cause anemia, reported a study published in the National Library of Medicine.

Can Anemia Cause Cancer?

Although cancer can cause anemia, anemia alone does not stimulate cancer cells to develop, explained Rogers. However, some inherited bone marrow failure syndromes, such as Fanconi anemia, Shwachman-Diamond syndrome, and Diamond-Blackfan anemia predispose you to cancer. Still, it is not anemia itself that causes cancer. Underlying defective cells are the main culprit in this case. Rogers added that if a malignant disease develops in someone with either of these genetic diseases, it is usually squamous cell carcinoma or leukemia.

How to cope with anemia and cancer?

Pacing yourself throughout the day and prioritizing activities is also helpful, as is learning to ask for help. Eating well and making sure you are hydrated is important both for anemia as well as coping with cancer itself.

What causes anemia in the body?

Blood loss leading to anemia can result from the loss of large amounts of blood (such as from surgery, menstruation, or a motor vehicle accident) or the chronic loss of microscopic amounts of blood (such as from polyps and tumors in the digestive tract, ulcers, or even hemorrhoids).

What Is Anemia?

Anemia is a deficit of red blood cells or their oxygen-transporting capacity. Anemia can result from conditions that affect red blood cells directly, or may instead be caused by iron deficiency. The hemoglobin molecules in your red blood cells contain iron, which serves to attach and transport oxygen to your tissues.

What happens when your hemoglobin is low?

When you have anemia (whether your red blood cell count is low or the hemoglobin in your red blood cells is low) you have a reduced capacity for delivering oxygen to the tissues in your body. This can lead to symptoms such as fatigue, shortness of breath, and even unconsciousness if your anemia is severe. 2 .

What to do if you have anemia without a known cause?

If you have anemia without a known cause (such as heavy menstrual bleeding), your healthcare provider may talk to you about screening for colon cancer, or other tests. 1

Why is anemia a symptom?

Anemia can result from conditions that affect red blood cells directly, or may instead be caused by iron deficiency. The hemoglobin molecules in your red blood cells contain iron, which serves to attach and transport oxygen to your tissues. Anemia is not a diagnosis, but rather a symptom with many possible causes.

What is it called when your red blood cells are not small?

A number of medical conditions, such as chronic kidney disease can result in anemia in which red blood cells are not small (as in iron deficiency anemia) nor large (as in pernicious anemia). This is known as anemia of chronic disease .

What cancers can cause anemia?

The cancer you have may make you more prone to becoming anemic. The cancers most closely associated with anemia are: Cancers that involve the bone marrow. Blood cancers like leukemia, lymphoma, and myeloma interfere with or destroy the marrow’s ability to make healthy blood cells. Other cancers that spread to the bone marrow can also cause anemia.

Why do people get anemia from chemotherapy?

People who develop anemia because of chemotherapy are at times given erythropoiesis-stimulating agents (ESAs) in hopes of increasing red blood cell production and decreasing the need for blood transfusions . Erythropoietin is a hormone in your kidneys that signals your bone marrow to make more red blood cells when needed.

What hormones make red blood cells?

Erythropoietin is a hormone in your kidneys that signals your bone marrow to make more red blood cells when needed. But recent studies have questioned the safety and effectiveness of ESAs, such as epoetin alfa ( Procrit, Epogen) and darbepoetin alfa (Aranesp).

What is it called when you don't have enough red blood cells?

Anemia is a condition in which your body does not have enough red blood cells, the cells that carry oxygen to body tissues. Mild anemia may not bother you much, but moderate anemia causes fatigue and headache, among other symptoms, and severe anemia can be life threatening.

What is the normal blood count for a woman with cancer?

A normal level in women is 12 grams per deciliter of blood (g/DL), in men it’s 15g/DL. If you show below-normal hemoglobin, your doctor may ...

Is chemotherapy anemia?

Anemia and Cancer Treatments. Almost all cancer patients receiving chemotherapy drugs are mildly anemic and some 80 percent develop a more serious problem, according to the National Anemia Action Council. The type of chemotherapy you’re receiving, the stage of your cancer, and your overall health play a role in whether you will develop anemia.

Does Blackfan anemia cause cancer?

Blackfan anemia, and Shwachman-Diamond syndrome, predispose a person to cancer. Still, it’s not the anemia that causes the cancer — underlyinsg defective cells are at fault, Rogers explains, adding that if cancer develops in these patients, it’s usually leukemia or squamous cell carcinomas.

What causes anemia in people with cancer?

Cancer treatments, such as chemotherapy and radiation therapy, as well as cancers that affect the bone marrow, can cause anemia. When you are anemic, your body does not have enough red blood cells. Red blood cells are the cells that that carry oxygen from the lungs throughout your body to help it work properly.

What are signs of anemia?

Signs of anemia may also include feeling dizzy or faint, headaches, a fast heartbeat, and/or pale skin.

How do you know if you have anemia?

Anemia and Cancer Treatment. Tell your doctor if you are extremely tired or have other signs of anemia. There are treatments that may help. Anemia is a condition that can make you feel very tired, short of breath, and lightheaded. Other signs of anemia may include feeling dizzy or faint, headaches, a fast heartbeat, and/or pale skin.

What tests are done to check for anemia?

You will have blood tests to check for anemia. Treatment for anemia is also based on your symptoms and on what is causing the anemia.

Is it normal to feel tired after radiation?

Most people getting radiation therapy feel fatigued. It does not mean that your cancer is getting worse. It does not mean that the treatment is not working. In fact, it is normal to feel very tired during this time. Listen to some tips that have helped others like you who are receiving radiation therapy.

What is the cause of anemia?

Anemia is the inadequate supply of healthy red blood cells. Anemia can be caused by many factors, and one of them is cancer. If a person suspects anemia due to having symptoms such as tiring easily, getting winded easily, pale skin, dizziness and chest pain, they may jump to the conclusion they have cancer – if they know ...

Is anemia a malignant disease?

However, anemia normally has non-malignant causes such as an intestinal ulcer, menstruation, poor diet and low iron levels. But some non-malignant causes are serious such as liver disease or lupus.

How to treat anemia in cancer patients?

Raise the hemoglobin level so that symptoms get better. The most common treatments of anemia in patients with cancer include: Iron therapy. Red blood cell transfusion, commonly known as blood transfusion.

How does anemia affect your life?

The first thing the doctor needs to know is how severe your anemia is. Anemia can affect your quality of life and has been found to shorten survival in people with cancer. It can make you feel very tired because cells in your body can’t get enough oxygen. In some cases, this lack of oxygen may be bad enough to threaten your life. Anemia can also make your heart work harder. So if you already have a heart problem, anemia can make it worse. Anemia can also make it hard for you to breath normally, making it challenging to do your usual activities.

How do ESAs help with anemia?

Erythropoiesis-stimulating agents (ESAs) Another way to treat anemia in some patients is to use drugs that tell the body to make more red blood cells. ESAs work like a hormone (called erythropoietin) made by the kidneys to help the body make its own new red blood cells.

What does it mean when you don't have enough red blood cells?

What is anemia? When you don’t have enough healthy red blood cells, you have a condition called anemia. This means your blood has lower than normal hemoglobin (Hgb) levels. Hemoglobin is the part of the red blood cell (RBC) that carries oxygen to all the cells in your body.

What causes red blood cells to be destroyed?

Red blood cells (RBCs) being destroyed by the body before they’re replaced. The body making fewer RBCs. Having chronic kidney disease. Having conditions like sickle cell disease or thalassemia (inherited disorders of red blood cells) A combination of any of these factors.

What causes a tumor to bleed?

Blood loss (this can be bleeding from a tumor, bleeding from cancer cells getting into blood vessels, or bleeding caused by other conditions like heavy menstruation or bleeding from a stomach ulcer)

Where is heme iron found?

Heme iron is found in animal products. Heme iron is more easily absorbed by the body than non-heme iron. Examples of foods that contain heme iron are:

How many people with cancer are anemic?

Cancer is one of the things we typically look for, particularly in people over 50 who are at greater risk of the disease. 2 . Research indicates that more than 30% of people with cancer will be anemic at the time of diagnosis with almost half experiencing iron deficiency anemia.

Why does bleeding cause anemia?

This is because the tumor releases certain chemicals that stimulate the formation of new blood vessels. As the tumor grows, the vessel bursts, leading to the loss of red blood cells. The bleeding, in turn, can give rise to an iron deficiency.

Why do people get iron deficiency anemia?

Iron deficiency anemia can be caused by everyday life situations such as menstruation, pregnancy, and breastfeeding (which is why iron supplements are often prescribed to women).

What is the lack of oxygen in the body?

Anemia is simply defined as either the lack of red blood cells that transport oxygen to body tissues or the lack of a protein called hemoglobin that red blood cells need to transport oxygen.

How do you know if you have colon cancer?

In term of colon cancer specifically, the most common symptoms can include: Unintentional weight loss (when not dieting or trying to lose weight) Loss of appetite. Nausea or vomiting. Changes in your bowel habits.

What does it mean when you have anemia?

Anemia is simply defined as either the lack of red blood cells that transport oxygen to body tissues or the lack of a protein called hemoglobin that red blood cells need to transport oxygen. Anemia can often go unnoticed. If symptoms do appear, they are generally minor. In some cases, a person may feel tired or lethargic.

How many types of anemia are there?

There are three main types of anemia, each of which is differentiated by their cause. They can be broadly defined as follows:

Why is anemia a problem?

Anemia symptoms and common causes of the problem. It is a term used when the body doesn’t have plenty of hemoglobin or healthy red blood cells. As well we know, cells of the body need continuously supply of oxygen to keep functioning well. The heart plays a key role to distribute oxygen and essential nutrients throughout the body.

Why are older people at high risk for anemia?

But the following are common factors to remember: Older adults are at high risk. Because they are also at high risk of having other medical conditions that can attribute to cause anemia. Women at childbearing age. Many times, menstrual bleeding often leads to iron-deficiency anemia, the most common form or anemia.

Why is anemia common in people with celiac disease?

Problems in the intestines. Your intestines play a key role to absorb essential nutrients from foods you have eaten. And to make adequate red blood cells, you need plenty of nutrients such as vitamins and minerals. Therefore anemia is pretty common in people with intestinal disorders such as celiac disease (gluten allergy) and Crohn’s disease.

Why do we need red blood cells?

You need plenty of healthy red blood cells to keep your body functioning well. Anemia (lack of red blood cells) can be attributed by lots of factors. In women, their menstruation periods often lead to deficiencies of iron and /or red blood cells. How about colon cancer? Can it cause anemia, too? Is so how?

Can colon cancer cause shortness of breath?

You may also have other symptoms such as weakness and shortness of breath. A challenging question – how does this problem occur in people with bowel cancers? Colon cancer can cause anemia in many different ways. But in general, the cancer itself and some cancer treatments may be the main causes.

Can anemia cause chest pain?

Numbness, typically in feet or /and hands. In general, the symptoms can vary. In severe case, anemia may also lead to serious or even life-threatening symptoms such as chest pain and trouble breathing.

Does menstrual bleeding cause anemia?

Many times, menstrual bleeding often leads to iron-deficiency anemia, the most common form or anemia. Pregnancy has an effect, too. In fact, the body is more likely to need more blood supply during pregnancy. There are also some types of anemia that link to a genetic trait (hereditary condition).

How to prevent anemia?

Treatments for anemia range from taking supplements to undergoing medical procedures. You might be able to prevent some types of anemia by eating a healthy, varied diet.

What causes aplastic anemia?

Causes of aplastic anemia include infections, certain medicines, autoimmune diseases and exposure to toxic chemicals. Anemias associated with bone marrow disease. A variety of diseases, such as leukemia and myelofibrosis, can cause anemia by affecting blood production in your bone marrow.

How to avoid iron deficiency anemia?

But you can avoid iron deficiency anemia and vitamin deficiency anemias by eating a diet that includes a variety of vitamins and minerals, including: Iron. Iron-rich foods include beef and other meats, beans, lentils, iron-fortified cereals, dark green leafy vegetables, and dried fruit. Folate.

What causes low red blood cells?

Vitamin deficiency anemia. Besides iron, your body needs folate and vitamin B-12 to produce enough healthy red blood cells. A diet lacking in these and other key nutrients can cause decreased red blood cell production. Some people who consume enough B-12 aren't able to absorb the vitamin. This can lead to vitamin deficiency anemia, also known as pernicious anemia.

Why do pregnant women have anemia?

Your bone marrow needs iron to make hemoglobin. Without adequate iron, your body can't produce enough hemoglobin for red blood cells. Without iron supplementation , this type of anemia occurs in many pregnant women.

What causes blood loss in the stomach?

It is also caused by blood loss, such as from heavy menstrual bleeding, an ulcer, cancer and regular use of some over-the-counter pain relievers, especially aspirin, which can cause inflammation of the stomach lining resulting in blood loss. Vitamin deficiency anemia.

Does low iron cause anemia?

A diet consistently low in iron, vitamin B-12 and folate increases your risk of anemia. Intestinal disorders. Having an intestinal disorder that affects the absorption of nutrients in your small intestine — such as Crohn's disease and celiac disease — puts you at risk of anemia. Menstruation.

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Causes

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Cancer and anemia are linked in many ways. If you have cancer, you may have anemia due to cancer itself or due to the treatments of cancer, such as chemotherapy. People with cancer may also develop anemia due to reasons other than cancer (for reasons that people without cancer may develop anemia.) If you …
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Symptoms

  • When you have anemia (whether your red blood cell count is low or the hemoglobin in your red blood cells is low) you have a reduced capacity for delivering oxygen to the tissues in your body. This can lead to symptoms such as fatigue, shortness of breath, and even unconsciousness if your anemia is severe. Iron deficiency can be the first symptoms of colon cancer. Because the ri…
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Adverse effects

  • In a 2016 study, 90 percent of people receiving chemotherapy for solid tumors were noted to have anemia.
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Epidemiology

  • In one study, 6 percent of people referred to a clinic due to iron deficiency anemia were found to have colon cancer. Of these people, the majority of cancers were in the right colon. Anemia at the time of diagnosis with colon cancer was linked with a poor prognosis in the past, but this does not appear to be the case in more recent studies.
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Diagnosis

  • If you are suffering one or more of these symptoms, especially if you have a known family history of colon cancer, do not delay talking to your doctor. Anemia is diagnosed on a complete blood count in which a low red blood cell count or low hemoglobin levels are noted. In addition to the levels, physicians look at other lab tests to learn more about the potential causes of anemia. So…
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Treatment

  • The treatment of anemia in people with cancer includes two primary steps. The first is the treatment of the underlying cause of the anemia, which can sometimes eliminate the cause. Treatment is also aimed at treating the anemia itself, especially if it is causing symptoms or has developed rapidly. Treatment of the underlying cause - The treatment of anemia will depend on t…
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Prognosis

  • Anemia can be difficult to cope with, especially the resultant fatigue. While fatigue is not dangerous on its own, many people find cancer fatigue to be one of the most annoying symptoms of cancer and cancer treatments.
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Prevention

  • Pacing yourself throughout the day and prioritizing activities is also helpful, as is learning to ask for help. Eating well and making sure you are hydrated are important both for anemia as well as coping with cancer itself.
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1.Anemia and Cancer: What Do You Need to Know?

Url:https://www.healthline.com/health/cancer/anemia-cancer

9 hours ago Cancer can impede your body’s ability to make red blood cells at a normal rate or intervene with your body’s ability to utilize stored iron. Cancers That Cause Anemia The type of cancer you have may make you more susceptible to becoming anemic. Here are the cancers most closely linked with anemia: Cancers involving the bone marrow.

2.Cancer and Anemia: Why Up to 80% of Cancer Patients …

Url:https://www.newhopemedicalcenter.com/blogs/cancer-and-anemia-why-up-to-80-of-cancer-patients-are-anemic/

16 hours ago  · The cancer you have may make you more prone to becoming anemic. The cancers most closely associated with anemia are: Cancers that involve the bone marrow. Blood cancers like leukemia, lymphoma, and...

3.The Link Between Cancer and Anemia | Everyday Health

Url:https://www.everydayhealth.com/anemia/anemia-cancer-link.aspx

11 hours ago Anemia can be caused by many factors, and one of them is cancer. If a person suspects anemia due to having symptoms such as tiring easily, getting winded easily, pale skin, dizziness and chest pain, they may jump to the conclusion they have cancer – if they know that cancer is associated with some cases of anemia.

4.Anemia and Cancer Treatment - Side Effects - NCI

Url:https://www.cancer.gov/about-cancer/treatment/side-effects/anemia

11 hours ago Certain tumor types (such as lung or ovary tumors) Having a low hemoglobin level before you had cancer Symptoms of anemia Anemia often starts slowly, so you may not notice symptoms at first. As your hemoglobin level gets lower you may have one or more of these symptoms: Fast heartbeat Fast breathing rate Shortness of breath (trouble breathing)

5.When Is Anemia a Symptom of Cancer? » Scary Symptoms

Url:https://scarysymptoms.com/2017/08/anemia-symptom-cancer/

16 hours ago  · While anemia is closely linked to cancer, the mechanism for its development can vary by the type of malignancy. Some types of cancer, like those affecting the bone marrow, directly impact the body’s ability to produce red blood cells, resulting in severe anemia. With colon cancer, it works somewhat differently.

6.Low Red Blood Cell Counts | Anemia - American Cancer …

Url:https://www.cancer.org/treatment/treatments-and-side-effects/physical-side-effects/low-blood-counts/anemia.html

2 hours ago  · Colon cancer can cause anemia in many different ways. But in general, the cancer itself and some cancer treatments may be the main causes. The following are some possible ways of how bowel cancers cause anemia! 1 2 Next Advertisement

7.Anemia as a Signal of Colon Cancer - Verywell Health

Url:https://www.verywellhealth.com/anemia-can-signal-colon-cancer-3974312

23 hours ago  · Certain diseases — such as cancer, HIV / AIDS, rheumatoid arthritis, kidney disease, Crohn's disease and other acute or chronic inflammatory diseases — can interfere with the production of red blood cells. Aplastic anemia. This rare, life-threatening anemia occurs when your body doesn't produce enough red blood cells.

8.How Does Colon Cancer Cause Anemia? - HealthClop

Url:https://www.healthclop.com/how-colon-cancer-cause-anemia/

36 hours ago

9.Anemia - Symptoms and causes - Mayo Clinic

Url:https://www.mayoclinic.org/diseases-conditions/anemia/symptoms-causes/syc-20351360

28 hours ago

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