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can b12 deficiency affect your bowels

by Mike Osinski Published 3 years ago Updated 2 years ago
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Gastrointestinal issues
A B12 deficiency may also cause diarrhea, nausea, constipation, bloating, gas, and other gastrointestinal symptoms ( 2 , 19 ). These issues can affect both adults and children ( 2 , 20 ).

Can vitamin B12 deficiency cause constipation?

Lacking in the vitamin could also cause dire effects with one’s bowel movements. According to the US National Heart, Lung and Blood Institute, constipation can be a sign of vitamin B12 deficiency. This is because the digestive tract can be impaired if a person is deficient in vitamin B12.

Can inflammatory bowel diseases affect your absorption of vitamin B-12?

Inflammatory bowel diseases impact your ability to digest food, which might affect your ability to absorb vitamin B-12. A difficulty absorbing vitamin B-12 is usually the cause of a vitamin deficiency. Crohn's disease causes inflammation of your digestive tract, which runs from your mouth to your anus.

What are the effects of vitamin B12 deficiency?

Vitamin B12 also helps prevent a type of anaemia which is known to make a person feel tired and weak. Lacking in the vitamin could also cause dire effects with one’s bowel movements. According to the US National Heart, Lung and Blood Institute, constipation can be a sign of vitamin B12 deficiency.

Does vitamin B12 cause diarrhea?

Does Vitamin B-12 Cause Diarrhea? 1 Vitamin B-12 Anemia. A lack of vitamin B-12 causes anemia because your body lacks sufficient amounts that you need to produce red blood cells. 2 Crohn's Disease. Crohn's disease is one of two major inflammatory bowel diseases, along with ulcerative colitis. ... 3 Ulcerative Colitis. ... 4 Celiac Sprue. ...

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Can B12 deficiency cause bowel problems?

Vitamin B-12 deficiency can affect the digestive tract. A lack of red blood cells means that not enough oxygen reaches the gut. Insufficient oxygen here may lead to a person both feeling and being sick. It may also cause diarrhea.

Does B12 affect bowels?

Side effects of B12 are uncommon but may include: diarrhea. constipation.

Can B12 deficiency cause IBS symptoms?

Vitamin B12 is one of the most common nutrient deficiencies we see with IBS and SIBO. Low vitamin B12 in itself can further exacerbate IBS symptoms you may already be experiencing such as diarrhea, fatigue, weakness, and brain fog.

Does B12 help with bowel movements?

However, some people may experience constipation as a result of a vitamin deficiency, such as vitamin B-12 deficiency. In those situations, a vitamin supplement may help relieve constipation.

Is vitamin B12 good for IBS?

Other supplements you may like to consider for IBS include: Folic Acid: Many people with IBS are low in folic acid, which is thought to be very good for general bowel health. Vitamin B12: Many people with IBS are deficient in iron, which Vitamin B12 helps the body to absorb.

How long does it take to recover from B12 deficiency?

Once you begin treating your vitamin B12 deficiency, it can take up to six to 12 months to fully recover. It is also common to not experience any improvement during the first few months of treatment.

What is the most common cause of B12 deficiency?

Diet. Some people can develop a vitamin B12 deficiency as a result of not getting enough vitamin B12 from their diet. A diet that includes meat, fish and dairy products usually provides enough vitamin B12, but people who do not regularly eat these foods can become deficient.

What foods to avoid if you have B12 deficiency?

There are certain foods that also need a cut-down in case of vitamin B12 deficiency. “Some foods and drinks can interfere with vitamin B complex intake like alcohol, caffeine and processed foods, etc should be avoided completely,” Shah added.

What are the signs of vitamin B12 deficiency?

Symptoms of vitamin B12 or folate deficiencyextreme tiredness.a lack of energy.pins and needles (paraesthesia)a sore and red tongue.mouth ulcers.muscle weakness.disturbed vision.psychological problems, which may include depression and confusion.More items...

Does low vitamin B12 cause constipation?

A B12 deficiency can cause symptoms like fatigue and constipation and could even lead to permanent neurological damage if left untreated.

What vitamin helps with bowel movements?

Magnesium Magnesium plays a number of essential roles in your body, and certain forms of this mineral may help with constipation. For example, research has shown that magnesium oxide, magnesium citrate, and magnesium sulfate all improve constipation symptoms.

What is the best supplement for regular bowel movements?

Bulk-forming fiber supplements include calcium polycarbophil (Equilactin, Fibercon), methylcellulose fiber (Citrucel), and psyllium (Fiber-Lax, Konsyl, Metamucil), and wheat dextrin (Benefiber). Unlike other laxatives, you can take these every day. They make the stool bigger and softer.

Can too much B12 cause digestive problems?

High doses of vitamin B-12, such as those used to treat a deficiency, might cause: Headache. Nausea and vomiting. Diarrhea.

Does B12 make you gassy?

In some people, high levels of B12 may cause gastrointestinal problems such as bloating and diarrhea.

Can low B12 cause diarrhea?

Macrocytosis (MCV >110 fL), diarrhea and neurologic symptoms strongly suggest vitamin B12 deficiency. Diarrhea from celiac sprue, bacterial overgrowth or pancreatic insufficiency can be seen with vitamin B12 deficiency because these are malabsorptive syndromes.

What are the signs of vitamin B12 deficiency?

Symptoms of vitamin B12 deficiencya pale yellow tinge to your skin.a sore and red tongue (glossitis)mouth ulcers.pins and needles (paraesthesia)changes in the way that you walk and move around.disturbed vision.irritability.depression.More items...

What is the best vitamin for bowel movements?

Vitamin B12 is a nutrient that helps keep the body’s nerve and blood cells healthy and helps make DNA, the genetic material in all cells. Vitamin B12 also helps prevent a type of anaemia which is known to make a person feel tired and weak. Lacking in the vitamin could also cause dire effects with one’s bowel movements.

Which food is the best source of vitamin B12?

Beef liver and clams, which are the best sources of vitamin B12.

Why are my stools so big?

During constipation a person’s stools often become difficult to push out and are larger than usual.

Does vitamin B12 make red blood cells?

A lack of vitamin B12 interferes with your body’s ability to make red blood cells.

Can B12 cause constipation?

According to the US National Heart, Lung and Blood Institute, constipation can be a sign of vitamin B12 deficiency.

Do plants have B12?

Plant foods have no vitamin B12 unless they are fortified, said the National Institutes of Health.

Is the digestive system the only body part to suffer from a deficiency?

However, the problems with the digestive tract are not the only body part to suffer due to a deficiency.

Why does lack of vitamin B12 cause anaemia?

Why does this occur. A lack of vitamin B12 interferes with your body's ability to make red blood cells. Insufficient red blood cells causes anaemia, or weak blood. As we age, so the symptoms may get worse which could lead to anaemia worsening.

Where can B12 be absorbed?

Without intrinsic factor, the body can't move vitamin B12 through the small intestine where it would otherwise be absorbed. Vitamin (Image: ) B12 foods are found naturally in a wide variety of animal foods and is added to some fortified foods.

What is the best vitamin for bowel movements?

Vitamin B12 is a nutrient that helps keep the body’s nerve and blood cells healthy and helps make DNA, the genetic material in all cells. Vitamin B12 also helps prevent a type of anaemia which is known to make a person feel tired and weak. Lacking in the vitamin could also cause dire effects with one’s bowel movements.

What does it mean when your bowels are hard?

Vitamin B12 deficiency: Hard or lumpy stools are one of the signs to spot in your bowel movements (Image: Getty Images) During constipation a person’s stools often become difficult to push out and are larger than usual. The stools are often dry, hard or lumpy.

Why is the digestive system impaired?

This is because the digestive tract can be impaired if a person is deficient in vitamin B12. A person’s digestive health relies on the healthy function of the stomach, small and large intestines, the colon and the rectum, and these tissues rely on B vitamins.

What foods have no B12?

Plant foods have no vitamin B12 unless they are fortified, said the National Institutes of Health. The health site advised: “You can get recommended amounts of vitamin B12 by eating a variety of foods including the following: Beef liver and clams, which are the best sources of vitamin B12.

Can B12 cause gassiness?

As well as constipation, vitamin B12 deficiency may lead to a person being overly gassy or suffering with diarrhoea.

How do you know if you have B12 deficiency?

Some of the most notable symptoms of vitamin B12 deficiency anaemia are feeling very tired, breathlessness even after little exercise, a sore mouth and tongue and heart palpitations.

What is the treatment for vitamin B12?

In many cases, particularly in more serious cases, vitamin B12 is treated with injections or tables to replace the missing vitamins.

Can B12 cause diarrhoea?

Having a vitamin B12 deficiency can play havoc on your digestive tract and this can cause diarrhoea. Some of the most notable symptoms of vitamin B12 deficiency anaemia are feeling very tired, breathlessness even after little exercise, a sore mouth and tongue and heart palpitations. But another symptom can also affect a person’s bowel habits.

Can you take vitamin B12 supplements between meals?

Then, depending on whether your B12 deficiency is related to your diet, you’ll either require B12 tablets between meals or regular injections. These treatments may be needed for the rest of your life.”.

What is the inflammatory bowel disease?

Inflammatory bowel diseases (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), are chronic inflammatory gastrointestinal disorders commonly thought to predispose to vitamin B 12 (cobalamin, Cbl) deficiency. The most important clinical manifestations of Cbl deficiency include nervous system dysfunction and megaloblastic anemia. 1,–3 Dietary Cbl must bind gastric-derived intrinsic factor (IF) for its absorption in the distal ileum. 3 CD can affect any segment of the gastrointestinal tract, whereas UC is confined to colon. One third to half of the patients with CD have isolated ileal disease and 30% to 55% have ileocolonic disease. 3,–5 Because ileal disease or resection may mediate Cbl malabsorption, patients with CD are assumed to be at greater risk for deficiency.

What is a CBL deficiency?

Biochemical Cbl deficiency is defined as low serum Cbl levels with confirmatory biomarker elevations (methylmalonic acid [MMA] and homocysteine [Hcy]). 11 These biomarker elevations confirm intracellular Cbl deficiency because they are substrates of reactions catalyzed by Cbl. Clinical deficiency is defined as a biochemical deficiency with megaloblastic anemia or neurological symptoms . 11,–14 The majority of Cbl deficiency is found in asymptomatic individuals without megaloblastic anemia. 11 This has been termed subclinical Cbl deficiency but is referred to as isolated biochemical deficiency here.

What is systematic review of CBL deficiency in CD and UC?

This systematic review of Cbl deficiency in CD and UC included studies analyzing both serum Cbl levels and absorption tests.

What is the purpose of a systematic review of CBL deficiency?

This systematic review aims to determine the risk of Cbl deficiency in both CD and UC, the specific disease-related risk factors for Cbl deficiency and the optimal management strategy. Definitions of Cbl deficiency employed in current literature were analyzed. Based on current literature, we have suggested an algorithm for evaluation and management of Cbl deficiency in IBD.

What biomarkers are used to diagnose CBL deficiency?

11,14,18 These stipulate that the diagnosis of Cbl deficiency in asymptomatic individuals should include 1 biomarker of circulating Cbl (serum Cbl or holotranscobalamin II) and 1 functional biomarker (MMA or Hcy) to confirm intracellular Cbl depletion. 11,14 Despite this, serum Cbl alone is still commonly used to screen for deficiency. 1,8,19 The sensitivity and specificity of serum Cbl are poor for isolated biochemical deficiency. 11,16,20,–24 A recent article in the New England Journal of Medicine outlined that false positive and negative rates may approach 50%. 25 When measuring serum Cbl, tests and cutoffs vary over time and between centers. 11 Furthermore, methodology is frequently suboptimal, leading to diagnostic misclassifications. 11 The Schilling's test helps to elucidate whether malabsorption occurs but does not help quantify the effect of this malabsorption on body stores. However, this test has largely disappeared for various reasons and is rarely available. 17, Table 1 outlines the NHANES diagnostic criteria and standard cutoff values for Cbl deficiency. The standard lower limit cutoff for serum Cbl is 148 pmol/L. 1,11,16 Normal upper limit cutoffs for MMA and Hcy are 270 nM/L 11,16 and 15 μmol/L, 26,27 respectively. Using these cutoffs, multiple population-based studies demonstrate deficiency rates ranging from 5% to 12%. 11

How to treat CBL malabsorption?

25 To achieve this, injected Cbl has traditionally been used with 10% of injected doses being retained in the body. 25 However, high-dose oral treatment has also been shown to be effective. 25 Oral Cbl can be absorbed by passive diffusion, even in patients with malabsorption. Oral doses of 1000 μg typically deliver 5 to 40 μg to the body. 25,28 Multiple randomized trials compared oral doses of 1000 to 2000 μg daily with parenteral therapy in patients with pernicious anemia, atrophic gastritis, or a history of ileal resection. At 3 to 4 months, both groups had symptom resolution, but oral therapy yielded higher Cbl levels and lower MMA levels than parenteral Cbl. 25,29,–31

Is CBL deficiency in CD a risk?

The risk of Cbl deficiency in CD is uncertain, making management decisions difficult. Screening for Cbl deficiency as part of routine follow-up visits for CD is often suggested. 6,32,–36 Furthermore, suggestions to follow and treat Cbl deficiency in IBD as in autoimmune gastritis have been made. 25 These measures may not be justified in all patients. Rather than using NHANES guidelines for diagnosis, gastroenterologists often manage patients with CD with isolated asymptomatic low serum Cbl with prolonged and frequently unjustified parenteral therapy associated with increased time and cost expenditures. 37,38

How Much B-12 Do You Need?

Eating foods that are rich in B-12, as well as taking supplements, is vital in order to raise your B-12 levels. Depending on your age, weight, and gender, your B-12 requirements may differ slightly.

What is the condition that causes ulcers in the intestines?

As mentioned above, ulcerative colitis is another inflammatory disease that affects the bowels. This is when the large intestine becomes inflamed, and this causes painful ulcers in the top layer of the lining of the large intestine, and diarrhea is a very common symptom of this condition.

How to help with constipation?

Drinking plenty of water is also vital for combating constipation. Six to eight a day should be sufficient for most people to help provide hydration and the smooth functioning of bowel movements. Surprisingly, vitamin B-12 isn’t found in vegetables or fruits, but mainly animal products such as: fish (salmon, trout, tuna, shellfish) meat.

Can Crohn's disease cause bowel problems?

These inflammatory bowel diseases can interfere with the way you absorb vitamin B-12, and this is the main cause for a deficiency. Crohn’s disease is known to cause inflammation of the digestive tract, which runs from your mouth to your anus. It can even cause arthritis, skin problems, fevers, rectal bleeding and pain in the abdomen.

Can you be at risk of a deficiency of B12?

A person who doesn’t eat enough vitamin B12-rich foods can be at risk of a deficiency in this vitamin.”. The National Heart, Lung, and Blood Institute. With that being said, keep reading to find out exactly what foods you need to eat!

Can Vitamin B-12 Cause Constipation?

A deficiency in vitamin B-12 can result in constipation, according to the US National Heart, Lung, and Blood Institute. This is because the health of the digestive tract relies heavily on the healthy functioning of the stomach, small and large intestines, colon and rectum, and these tissues rely on B vitamins.

What happens when you don't have enough B12?

In fact, the red blood cells produced when someone is deficient are larger than normal and known as macrocytosis. A deficiency can also lead to anemia, which means your body does not have enough red blood cells to perform normally. Understanding the perceivable symptoms that accompany a B12 deficiency is important, ...

Why is it important to speak with your doctor about vitamin B12?

The key takeaway? A vitamin B12 deficiency can occur for a variety of reasons, which is why it’s important to speak with your doctor. Together you can decide whether vitamin b12 testing needs to be completed, symptoms, risk factors and the possibility of a vitamin B12 deficiency .

What does it mean when your stomach is atrophying?

Atrophy in the stomach can be a sign of pernicious anemia but also a key indicator of other disorders as well. We can also see vitamin B12 deficiency in those who undergo major surgeries like gastric bypass.

Why is vitamin B12 important?

As previously mentioned, vitamin B12 is vital in the creation of cells within our body. Red blood cells help carry oxygen throughout the body and require vitamin B12 to function. If vitamin B12 is low this causes a change in the size of the red blood cells. In fact, the red blood cells produced when someone is deficient are larger than normal ...

How to get B12?

For those who receive enough B12 in their diet but remain deficient may need to take the next step and get extra vitamin B12 through other sources. Vitamin B12 can be given via injection or high doses of oral medication to increase the stores of B12 in the body.

How long can you go without B12?

Generally, we have large stores of vitamin B12 in our body and can go months, even years without it before reaching low levels. However, it’s important to identify a deficiency early on to prevent the consequences of low B12.

What are the effects of vitamin D?

For example, low vitamin D levels can lead to osteoporosis and an increased risk of fractures. One essential vitamin that is important for our body to function properly is vitamin B12.

Why is it important to know if you have a B12 deficiency?

It's important to determine if the cause of these symptoms is a B12 deficiency, because a severe case may cause brain damage.

How to know if you have a B12 deficiency?

Here are some common early symptoms of a deficiency to look out for. 1. Fatigue or Feeling Weak.

What does it mean when your B12 is low?

Feeling fuzzy or forgetful is another common sign of too-low B12 levels, according to Harvard Health Publishing. Some people experience memory loss, and others have trouble with thinking and reasoning.

Why is fatigue a key indicator of low B12?

Crifase says fatigue is a key indicator of low B12 because it can compromise your circulatory system. In other words, your blood can't circulate oxygen the way it's supposed to, leaving you feeling less than 100 percent. Advertisement. 2.

Does meat have B12?

People who eat meat tend to get plenty of B12, since its found in animal-based foods. Vegetarians or vegans may struggle to get enough, though, and many people may experience a deficiency as they take more laps around the sun. "Like most vitamins, B12 is absorbed in the digestive system," Crifase says.

What is the cause of a vitamin deficiency?

Crohn's Disease. Crohn's disease is one of two major inflammatory bowel diseases, along with ulcerative colitis. Inflammatory bowel diseases impact your ability to digest food, which might affect your ability to absorb vitamin B-12. A difficulty absorbing vitamin B-12 is usually the cause of a vitamin deficiency.

What is the inflammatory bowel disease?

Ulcerative colitis is the other main inflammatory bowel disease. Diarrhea is one of the main symptoms of ulcerative colitis. The lining of the large intestine becomes inflamed if you have ulcerative colitis, causing ulcers in the top layer of the lining of the large intestine. This includes the colon and the rectum.

Why does my stool runny?

Image Credit: Jupiterimages/Polka Dot/Getty Images. Diarrhea is the result of your body eliminating stool before the large intestine can properly absorb water back into your body, which causes the stool to be runny and watery. Diarrhea is a symptom of several conditions that relate to a deficiency of vitamin B-12.

Does Crohn's disease cause diarrhea?

It may also cause skin problems, arthritis, fever, rectal bleeding and abdominal pain. A vitamin B-12 deficiency does not actually cause diarrhea in Crohn's disease, but a resulting deficiency from Crohn's may lead to more diarrhea as you become ...

Can gluten cause cancer?

The combination of symptoms may indicate celiac. The best thing is to keep eating wheat products and to request your GP tests you for it. If the test is positive further investigations will be triggered and you must attend them, as celiac can after many years cause cancer if you continue to eat gluten.

Is B12 a link to cancer?

Your symptoms are not minor. They may however be unconnected. As for cancer risk from B12 deficiency. Yes there is a link but usually over a very long time period in which the B12 deficiency was not fully corrected or was left untreated.

Can B12 deficiency cause GI bleeding?

Such as an auto-immune disorder called pernicious anemia, some prescribed drugs such as metformin cause it, inadequate B12 in the diet and celiac disease (severe gluten allergy). I have also had GI bleeding but it was not necessarily connected with B12 deficiency but caused by a duo denal ulcer. Your young age does not exclude the possibility of these issues.

Is low B12 bad for you?

To answer your specific question, there is a possible link between low B12 and digestive cancer, but that is only half the story. The risk of digestive cancer at age 24 is very low, and so all the reduced B12 might do is increase that very low risk ever so slightly. Resulting in a risk that is still very low. If I were in your situation and at your age, I would not be unduly concerned.

Is low B12 connected to Colon/Bowel/Rectal cancer?

Hi, I’m worried as being diagnosed with pernicious anaemia by my gp in 2000 I was told I would need b12 injections for the rest of my life. In 2015 I was at a different surgery where I was refused b12 and told unnecessary . Same year I was diagnosed with breast cancer and now how secondary breast cancer which is incurable. My oncologist had to stop my palliative chemo due to to low platelets and has now put me on b12 . I’m 64 now and worried all the years without b12 have caused the cancer . Thanks in advance .

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