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can calcium channel blockers cause gerd

by Shawn Simonis Published 3 years ago Updated 2 years ago
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Recent studies suggest that calcium channel blockers (CCBs), and particularly nifedipine, increase the risk of GERD by significantly reducing the tone of the LES, increasing esophageal exposure to gastric acid and reducing the amplitude and duration of esophageal peristalsis [6,7,8].Jan 31, 2012

Does calcium channel blockers cause acid reflux?

Taking non-steroidal anti-inflammatory medications like ibuprofen or aspirin; calcium channel blockers for heart conditions and drugs that slow the contractions of the muscles in the intestines can all lead to acid reflux.

Can amlodipine cause reflux?

Amlodipine and other dihydropyridines can cause heartburn by relaxing the lower oesophageal sphincter.

Which blood pressure medications cause acid reflux?

High blood pressure medications. Calcium channel blockers such as nifedipine (Procardia) and beta blockers such as propranolol (Inderal) can also cause heartburn.

Can amlodipine worsen GERD?

Some medications may also lead to symptoms of GERD. These may relax the LES or may increase gastric acid secretion. They include: calcium-channel blockers (e.g. Amlodipine, Nifedipine etc.

Does amlodipine cause digestive problems?

Serious side effects you have stomach problems – severe pain in your stomach, with or without diarrhoea (whether it has blood in it or not), feeling sick and being sick (nausea and vomiting) – these can be signs of pancreatitis.

What is the most common side effect of amlodipine?

Edema, such as leg swelling You may have edema (swelling) while you're taking amlodipine oral tablets. This was the most common side effect reported in studies of the drug. Swelling from amlodipine oral tablets typically happens in your arms, feet, hands, or legs.

How do you permanently cure GERD?

Surgery for GERD The goal of surgery for reflux disease is to strengthen the anti-reflux barrier. During a procedure known as a Nissen fundoplication, your surgeon wraps the upper part of your stomach around the lower esophagus. This enhances the anti-reflux barrier and can provide permanent relief from reflux.

Why will my acid reflux not go away?

Then it starts—the burning in the chest, the lump in your throat, and the pain of acid reflux that won't go away without medicine. Chronic heartburn that doesn't go away despite popping several Tums or Rolaids could indicate that you've got GERD.

How do you get rid of acid reflux in your throat fast?

10 home remedies for heartburnEat a ripe banana. ... Chew sugar-free gum. ... Keep a food journal and avoid trigger foods. ... Resist the urge to overeat or eat quickly. ... Avoid late meals, snacking before bed and eating before exercising. ... Wear loose-fitting clothing. ... Adjust your sleep position.More items...•

Can I take antacids with amlodipine?

Interactions between your drugs No interactions were found between amlodipine and Heartburn Antacid Extra Strength.

Can I take omeprazole and amlodipine together?

Conclusion. Adding omeprazole to long-term amlodipine therapy in patients with hypertension and ARD may lead to a significantly more pronounced antihypertensive effect in patients genotyped CYP2C19 IMs.

Is amlodipine acidic or basic?

Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called dihydropyridine calcium channel blockers....Structure for Amlodipine besylate (DBSALT001054)PropertyValueSourcepKa (Strongest Acidic)19.12ChemAxonpKa (Strongest Basic)9.45ChemAxon17 more rows

Can I take antacids with amlodipine?

Interactions between your drugs No interactions were found between amlodipine and Heartburn Antacid Extra Strength.

Can you take Gaviscon with amlodipine?

Interactions between your drugs No interactions were found between amlodipine and Gaviscon Regular Strength Liquid.

Can I take omeprazole and amlodipine together?

Conclusion. Adding omeprazole to long-term amlodipine therapy in patients with hypertension and ARD may lead to a significantly more pronounced antihypertensive effect in patients genotyped CYP2C19 IMs.

What foods should I avoid when taking amlodipine?

Is there any food or drink I need to avoid? Having large amounts of grapefruit or grapefruit juice can increase the concentration of amlodipine in your body and make side effects worse. If you are affected, you may have to avoid eating grapefruit or drinking grapefruit juice while taking amlodipine.

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