
Can you get high off of diphenoxylate? When prescribed in high doses, diphenoxylate can cause a sense of false euphoria in the user. Continued use often requires the user to take more of the drug in order to achieve this mood elevating affect. Signs of diphenoxylate abuse often include: Fatigue. Click to see full answer.
What should I know about taking diphenoxylate before taking it?
Before having any laboratory test (especially those that involve methylene blue), tell your doctor and the laboratory personnel that you are taking diphenoxylate. Do not let anyone else take your medication. Diphenoxylate is a controlled substance.
Is it safe to give a 2 year old diphenoxylate?
Diphenoxylate should not be given to children younger than 2 years of age. Diphenoxylate is in a class of medications called antidiarrheal agents. It works by decreasing activity of the bowel.
What are the signs of diphenoxylate abuse?
When prescribed in high doses, diphenoxylate can cause a sense of false euphoria in the user. Continued use often requires the user to take more of the drug in order to achieve this mood elevating affect. Signs of diphenoxylate abuse often include:
What are the side effects of Adderall diphenoxylate?
Diphenoxylate. This medication is often mixed with other drugs to lower the risk of abuse. Brand name medications containing diphenoxylate include Lomotil, Nisentil and Dipidolor. Common side effects of diphenoxylate are similar to those of other opioids and include nausea, vomiting, headache, restlessness, confusion and changes in mood.

How much diphenoxylate can get you high?
This reduces the need for higher doses of these agents, which in turn reduces the potential for abuse. Although studies have shown that loperamide elicits very little euphoria, even at high doses, diphenoxylate does induce an opiate-like euphoric effect at higher doses (40 to 60 mg).
What happens if you take too much diphenoxylate?
What happens if I overdose on Lomotil (Atropine And Diphenoxylate)? Early overdose symptoms include weakness, blurred vision, slurred speech, feeling hot, fast heartbeats, slowed breathing, fainting, seizure, or coma. Report any early overdose symptoms to your doctor as soon as possible.
Is diphenoxylate a opioid?
Diphenoxylate is an opioid, which also contains atropine in its commercially available form as a deterrent to overdosing.
Can Lomotil be abused?
Lomotil (diphenoxylate atropine combination) has been in use as an antidiarrhoeal agent. Due to presence of opioid (diphenoxylate), there are chances of abuse.
Is diphenoxylate addictive?
Drug Abuse And Dependence In doses used for the treatment of diarrhea, whether acute or chronic, diphenoxylate has not produced addiction.
Can atropine get you high?
The euphoria gained from abusing diphenoxylate/atropine is said to mimic the effects of more highly-regulated medications such as heroin and oxycodone. Usually dosed at a total of 5 mg of diphenoxylate by mouth 3-4 times daily, toxicity can begin at 75-100 mg per day.
How does diphenoxylate make you feel?
Side effects of diphenoxylate include abdominal bloating and pain, nausea and vomiting and constipation. Because there is systemic absorption, diphenoxylate can also cause central nervous system opioid effects such as confusion, drowsiness, euphoria, dizziness, headache, and respiratory depression.
How strong is diphenoxylate?
Conversely, diphenoxylate is metabolized into difenoxin which is upwards of 250 times more potent than its parent-drug. This active metabolite readily crosses the BBB to produce depressive effects on the CNS, which in turn, produces depressive effects on the gut as well.
Is diphenoxylate a pain reliever?
Diphenoxylate is similar to opioid pain relievers, but it acts mainly to slow the gut. Atropine belongs to a class of drugs known as anticholinergics, which help to dry up body fluids and also slow gut movement.
Is Lomotil an opioid?
Lomotil (diphenoxylate / atropine) is a combination of two medications. Diphenoxylate is an opioid. It binds to certain proteins in your gut, called mu-opioid receptors, to control and slow the movement of your intestines (gut).
Does Lomotil have a narcotic in it?
Lomotil is a Schedule V controlled substance, which means it has a medical use but may be misused. It contains small quantities of narcotics (powerful pain relievers also called opioids). Diphenoxylate, one of the ingredients in Lomotil, is itself a Schedule II controlled substance.
What class of drug is diphenoxylate?
Diphenoxylate is in a class of medications called antidiarrheal agents.
What is diphenoxylate used for?
Diphenoxylate is an opioid used for the treatment of diarrhea that works to decrease muscle movement in the intestines, lengthening the time it takes for materials to pass through the body. When used in its purest form, diphenoxylate is classified as a Schedule II drug. This medication is often mixed with other drugs to lower the risk of abuse. Brand name medications containing diphenoxylate include Lomotil, Nisentil and Dipidolor. Common side effects of diphenoxylate are similar to those of other opioids and include nausea, vomiting, headache, restlessness, confusion, and changes in mood.
Can diphenoxylate cause false euphoria?
When prescribed in high doses, diphenoxylate can cause a sense of false euphoria in the user. Continued use often requires the user to take more of the drug in order to achieve this mood elevating affect. Signs of diphenoxylate abuse often include:
mkultra5979 Silver Member
My best friend wants to try diphenoxylate recreationally. Diphenoxylate penetrates blood–brain barrier. We searched everything but we only found opinions and not dosages. We know that there are much more good opiates out there, but tonight he has only these small pills. He's desperate to get high...lol
Potter Platinum Member & Advisor
when approaching any new drug, you don't just pop 10x the normal dose and hope for the best. You start small, and over the course of a number of well spaced experiments, gradually increase the dose till a desired state is achieved. This very well could mean two or more months before a "high" is found.
mkultra5979 Silver Member
Many thanks for the help Potter. Atropine will make someone sick, you are right, I was reading about it.
Potter Platinum Member & Advisor
I suspect a water extraction won't help on this one, but to be honest, I only have a rudimentary background in planning novel chemistry work. Pull up the drugs on a Merck Index, and find something that will dissolve one, not the other, then figure out a way to get the good stuff out of the solvents.
mkultra5979 Silver Member
I am a anesthesiology nurse (but I work another job) and I know about atropine, we were using it IV to wake up the patient - and for cardiac failure (1 mg or more).
Totse Newbie
I have been going through withdrawals for the last 8 days from Subutex ... I've been having severe runs because of the w/d's and my dad gave me one of these pills.
What to do if you are allergic to diphenoxylate?
Before taking diphenoxylate, tell your doctor and pharmacist if you are allergic to diphenoxylate, atropine, any other medications, or any of the other ingredients in diphenoxylate tablets or solution. Ask your pharmacist for a list of the ingredients. tell your doctor and pharmacist what other prescription and nonprescription medications, ...
How often should I take diphenoxylate?
Diphenoxylate comes as a tablet and solution (liquid) to take by mouth. It is usually taken as needed up to 4 times a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take diphenoxylate exactly as directed.
What is diphenoxylate used for?
Diphenoxylate is used along with other treatments such as fluid and electrolyte replacement for the treatment of diarrhea. Diphenoxylate should not be given to children younger than 2 years of age. Diphenoxylate is in a class of medications called antidiarrheal agents. It works by decreasing activity of the bowel.
How long does diphenoxylate help with diarrhea?
Ask your pharmacist if you have questions about how to measure a dose. Your diarrhea symptoms should improve within 48 hours of treatment with diphenoxylate.
How do you know if you overdosed on a sulfate?
Symptoms of overdose may include the following: fever, fast heartbeat, decreased urination, flushing, dryness of the skin, nose, or mouth. dryness of the skin, nose, or mouth. changes in the size of pupils (black circles in the middle of the eyes) uncontrollable eye movements. restlessness. flushing.
Can diphenoxylate make you dizzy?
before having surgery, including dental surgery, tell the doctor or dentist that you are taking this medicine. you should know that this drug may make you drowsy and dizzy.
Can you take a double diphenoxylate?
However, if it is almost time for the next dose, skip the missed dose and continue the regular dosing schedule. Do not take a double dose to make up for a missed one.
What happens if you stop taking a sulfate supplement?
Consult your doctor or pharmacist for more information. If you suddenly stop using this medication, you may have withdrawal symptoms (such as stomach cramps, nausea, vomiting ).
What to do if side effects persist?
If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Where to report side effects?
You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. Precautions.
Can atropine cause diarrhea?
Atropine belongs to a class of drugs known as anticholinergics, which help to dry up body fluids and also slow gut movement.This medication should not be used to treat diarrhea caused by certain types of infection (such as C. difficile-associated diarrhea following antibiotic therapy).
Can you increase your diahria medication?
In children, the dosage is also based on weight. If you need to continue treatment once your diarrhea is controlled, your doctor may direct you to lower your dosage. Do not increase your dose, take it more often, or use it for longer than prescribed.
Can drug interactions change your medication?
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist.
Can you take diphenoxylate with atropine?
Before taking diphenoxylate with atropine, tell your doctor or pharmacist if you are allergic to either drug; or to hyoscyamine; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Is diphenoxalate a narcotic?
First Lomotil’s main ingredient diphenoxalate is a opioid narcotic and it is structurally similar and similar in effect to meperidine, which is Demerol . Atropine is added to discourage abuse but it still happens and many people report getting high on dosages that exceed normal dosing.
Does lomotil make you high?
Lomotil should not give you a high at all. It is used for diarrhea. If it makes you high you would be the first I'm sure. Hope this is the info you are looking for
