Precautions
If you use pantoprazole for longer than 3 years, you could develop a vitamin B-12 deficiency. Talk to your doctor about how to manage this condition if you develop it. fever, rash, or cold symptoms (most common in children). This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
What are the side effects of pantoprazole?
Pantoprazole Usage. If you forget to take a dose of pantoprazole, take it as soon as you remember. If it is almost time for your next dose, do not take the missed dose. Take the next dose at your regular time. Do not take two doses to try to make up for a missed dose.
What should I do if I miss a dose of pantoprazole?
For oral dosage forms (delayed-release tablets or suspension): For erosive esophagitis: Adults—40 milligrams (mg) once a day for up to 8 weeks. Your doctor may want you to take pantoprazole for more than 8 weeks for certain conditions. Children 5 years of age and older weighing 40 kilograms (kg) or more—40 mg once a day for up to 8 weeks.
How long should I take pantoprazole for?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while using pantoprazole? This medicine can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor.
Where do I go to get help with pantoprazole?
What happens if you take too many pantoprazole?
Taking pantoprazole for more than a year may increase your chances of certain side effects, including: bone fractures. gut infections. vitamin B12 deficiency – symptoms include feeling very tired, a sore and red tongue, mouth ulcers and pins and needles.
How much pantoprazole can you take in a day?
Adults—At first, 40 milligrams (mg) 2 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.
Is pantoprazole lethal?
In case of overdose, treatment should be symptomatic and supportive. Single intravenous doses of pantoprazole at 378, 230, and 266 mg/kg (38, 46, and 177 times the recommended human dose based on body surface area) were lethal to mice, rats and dogs, respectively.
Can I take 80 mg of pantoprazole?
For the long-term management of Zollinger-Ellison-Syndrome and other pathological hyper secretory conditions patients should start their treatment with a daily dose of 80 mg (2 tablets of Pantoprazole 40 mg).
Can I take more than 40 mg of pantoprazole?
Taking more pantoprazole than recommended, such as pantoprazole 40mg twice a day, is not any more effective than 40mg once a day for GERD symptoms, and can mask more serious underlying conditions, such as severe ulcers or reflux disease. In addition, there is a higher risk of side effects.
Can I have pan 40 twice a day?
Usually, PAN 40 Tablet is taken once a day, first thing in the morning. If you take PAN 40 Tablet twice a day, take 1 dose in the morning and 1 dose in the evening. The tablets should be swallowed whole (remember not to be chewed or crushed) and taken at least 1 hour before a meal with some water.
How long does it take for pantoprazole to kick in?
You should start to feel better within 2 to 3 days. It may take up to 4 weeks for pantoprazole to work properly. You may still have symptoms during this time.
Can I take 2 pantoprazole 20 mg?
The recommended oral dose is one Pantoprazole 20 mg tablet per day. A daily dose of 20 mg pantoprazole should not be exceeded in patients with severe liver impairment (see section 4.4).
Can pantoprazole cause kidney damage?
The underlying mechanism of pantoprazole-induced acute kidney injury is complex. Sensitivity to pantoprazole is the primary reason for the onset of acute kidney injury and may only be confirmed by renal pathology (27).
Can I take 120 mg of pantoprazole?
Conclusions: Pantoprazole was able to control acid hypersecretion in ZES patients when administered in doses between 40 and 160 mg daily. An initial dose of 120 mg given before further titration of the drug regimen appears to be a reasonable therapeutic strategy.
Does pantoprazole make you gain weight?
You may have weight gain while you're taking pantoprazole oral tablets. Both weight gain and weight loss were reported after the drug's initial studies were done. Additionally, you may gain weight if you have edema (swelling) or bloating, which are possible side effects of pantoprazole.
How long does it take for pantoprazole to heal esophagus?
When used to treat GERD, guidelines recommend a 4- to 8-week treatment course; if an improvement is seen after 4 to 8 weeks consider a possible wean. May be used for up to 12 months to maintain the healing of erosive esophagitis.
Can I take 120 mg of pantoprazole?
Conclusions: Pantoprazole was able to control acid hypersecretion in ZES patients when administered in doses between 40 and 160 mg daily. An initial dose of 120 mg given before further titration of the drug regimen appears to be a reasonable therapeutic strategy.
Can you take pantoprazole twice a day?
For the treatment and maintenance of GERD, pantoprazole is usually taken once a day. For the treatment of conditions where the stomach produces too much acid, pantoprazole is usually taken twice a day.
How long does it take for pantoprazole to kick in?
You should start to feel better within 2 to 3 days. It may take up to 4 weeks for pantoprazole to work properly. You may still have symptoms during this time.
Is it better to take pantoprazole in the morning or at night?
Available in capsule and powder form, the 40-mg dose given at bedtime has been shown to be superior to pantoprazole 40 mg given at dinner in control of overnight pH.
When should you take pantoprazole?
Take pantoprazole tablets immediately before a meal, preferably in the morning. Pantoprazole tablets may be taken with food or on an empty stomach....
Can pantoprazole cause anxiety?
Pantoprazole may cause side effects, but it does not seem to cause anxiety. Some people in clinical trials reported headaches while taking pantopra...
How long does pantoprazole take to work?
Pantoprazole starts to work within 2 and a half (2.5) hours – this is the time it takes for it to block the secretion of acid in the stomach - and...
Pantoprazole vs. omeprazole: What's the difference between them?
Pantoprazole and omeprazole are both medicines from the class of medications called proton pump inhibitors (PPIs). The approved uses for pantoprazo...
Can you take pantoprazole 40 mg twice a day?
The usual dosage for pantoprazole 40mg is 40mg once a day if you are buying it without a prescription or a physician's evaluation of your symptoms....
How long can I take pantoprazole?
You should only take pantoprazole for up to 8 weeks if you are buying it without a prescription or a physician evaluation of your symptoms. This is...
Does pantoprazole cause bloating?
Bloating has been reported as a side effect of regular pantoprazole use. One study reported bloating in 43% of patients taking a similar proton pum...
What color ink is used on pantoprazole?
40 mg pantoprazole, yellow oval biconvex tablets imprinted with PROTONIX (brown ink) on one side
What is the phone number to call for Protonix?
If overexposure to PROTONIX occurs, call your Poison Control Center at 1-800-222-1222 for current information on the management of poisoning or overdosage.
What is the active ingredient in Protonix?
The active ingredient in PROTONIX (pantoprazole sodium) For Delayed-Release Oral Suspension and PROTONIX (pantoprazole sodium) Delayed-Release Tablets, a PPI, is a substituted benzimidazole, sodium 5- (...
Is Protonix contraindicated?
PROTONIX is contraindicated in patients with known hypersensitivity to any component of the formulation or any substituted benzimidazole. Hypersensitivity reactions may include anaphylaxis, anaphylactic shock,...
Is Protonix delayed release?
PROTONIX is supplied as delayed-release granules in packets for preparation of oral suspensions or as...
Is pantoprazole lethal to dogs?
Single oral doses of pantoprazole at 709 mg/kg, 798 mg/kg, and 887 mg/kg were lethal to mice, rats, and dogs, respective ly. The symptoms of acute toxicity were hypoactivity, ataxia, hunched sitting, limb-splay, lateral position, segregation, absence of ear reflex, and tremor.
Can you take Pantoprazole with hemodialysis?
Spontaneous post-marketing reports of overdose are generally within the known safety profile of PROTONIX. Pantoprazole is not removed by hemodialysis. In case of overdosage, treatment should be symptomatic and supportive.
How should I use pantoprazole?
Take pantoprazole exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
What should I avoid while using pantoprazole?
This medicine can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.
What other drugs will affect pantoprazole?
Tell your doctor about all your other medicines. Some may interact with pantoprazole, especially:
How long does it take for 40 mg of pantoprazole to work?
40 mg orally twice daily for 7 days, commonly in conjunction with clarithromycin and either amoxicillin or metronidazole to eradicate Helicobacter pylori, followed with 40 mg pantoprazole orally once daily until day 28. Triple therapy has resulted in eradication rates of greater than 95%.
How is pantoprazole taken?
Pantoprazole is taken by mouth (oral) or given as an infusion into a vein (injection). A healthcare provider may teach you how to properly use the injection by yourself.
What is the effect of pantoprazole on the stomach?
Pantoprazole is a proton pump inhibitor that decreases the amount of acid produced in the stomach.
What happens if you are allergic to pantoprazole?
Get emergency medical help if you have signs of an allergic reaction to pantoprazole: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
How much pantoprazole is in Protonix?
PROTONIX I.V. (pantoprazole sodium) is supplied in a single-dose vial as a white to off-white freeze-dried powder for reconstitution containing 40 mg of pantoprazole.
How much pantoprazole is lethal to dogs?
Single intravenous doses of pantoprazole at 378, 230, and 266 mg/kg (38, 46, and 177 times the recommended human dose based on body surface area) were lethal to mice, rats and dogs, respectively. The symptoms of acute toxicity were hypoactivity, ataxia, hunched sitting, limb-splay, lateral position, segregation, absence of ear reflex, and tremor.
Is Protonix I.V. short term?
PROTONIX I.V. is indicated for short-term treatment (7 to...
Is Protonix I.V. contraindicated?
PROTONIX I.V. is contraindicated in patients with known hypersensitivity reactions including anaphylaxis to the formulation or any substituted benzimidazole. Hypersensitivity reactions may include...
How is pantoprazole taken?
Pantoprazole is taken by mouth (oral) or given as an infusion into a vein (injection). A healthcare provider may teach you how to properly use pantoprazole injection by yourself.
What to do if someone overdoses on Pantoprazole?
If you think you or someone else may have overdosed on: Pantoprazole (Protonix) , call your doctor or the Poison Control center. (800) 222-1222. If someone collapses or isn't breathing after taking Pantoprazole (Protonix), call 911. 911.
How long does pantoprazole cause magnesium levels to drop?
Using pantoprazole for longer than three months can cause low magnesium levels.
How long does pantoprazole cause nausea?
If you use pantoprazole for longer than 3 years, you could develop a vitamin B-12 deficiency. Talk to your doctor about how to manage this condition if you develop it. Common side effects may include: headache, dizziness; stomach pain, gas, nausea, vomiting, diarrhea; joint pain; or.
What are the side effects of pantoprazole?
sudden pain or trouble moving your hip, wrist, or back; bruising or swelling where intravenous pantoprazole was injected; kidney problems -- fever, rash, nausea, loss of appetite, joint pain, urinating less than usual, blood in your urine, weight gain;
How old do you have to be to take pantoprazole?
Pantoprazole is not approved for use by anyone younger than 5 years old.
What are the side effects of Cerner Multum?
stomach pain, gas, nausea, vomiting, diarrhea; joint pain; or. fever, rash, or cold symptoms (most common in children). This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Cerner Multum.
What to do if you miss a pantoprazole?
If you miss a dose of pantoprazole, take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. You can take your next dose at its usual time. Don’t take two doses to make up for a missed dose. Doing so can increase your risk for side effects from the drug.
What are pantoprazole oral tablet’s side effects?
Like most drugs, pantoprazole oral tablets may cause mild or serious side effects . The lists below describe some of the more common side effects that pantoprazole may cause. These lists don’t include all possible side effects.
What is pantoprazole oral tablet?
If you have problems with your esophagus or stomach, your doctor may prescribe pantoprazole for you.
What should be done in case of overdose?
Don’t take more pantoprazole oral tablets than your doctor prescribes. Using more than this can lead to serious side effects.
What is the name of the drug that is a proton pump inhibitor?
Pantoprazole belongs to a group of drugs called proton pump inhibitors (PPIs).
What are the side effects of pantoprazole?
Mild side effects of pantoprazole oral tablets that have been reported include: belly pain. diarrhea.
What are the interactions with pantoprazole?
Interactions. Taking medications, vaccines, foods, and other things with a certain drug can affect how the drug works. These effects are called interactions. Before taking pantoprazole oral tablets, be sure to tell your doctor about all medications you take, including prescription and over-the-counter types.
How long can you take pantoprazole?
Adults—40 milligrams (mg) once a day for up to 8 weeks. Your doctor may want you to take pantoprazole for more than 8 weeks for certain conditions. Children 5 years of age and older weighing 40 kilograms (kg) or more—40 mg once a day for up to 8 weeks.
How to store a med?
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Ask your healthcare professional how you should dispose of any medicine you do not use.
How to take a granule of apple juice?
Open packet. 2. Mix the packet contents with 1 teaspoon of apple juice in a small cup or container. 3. Stir for 5 seconds (granules will not dissolve) and swallow it immediately or take it at least 30 minutes before a meal. 4.
How much Zollinger is needed for children?
For Zollinger-Ellison syndrome: Adults—At first, 40 milligrams (mg) 2 times a day. Your doctor may increase your dose as needed.
Can you take IBM Micromedex more than once?
Drug information provided by: IBM Micromedex. Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. This medicine comes with a Medication Guide. Read and follow these instructions carefully.
Usual Adult Dose for Erosive Esophagitis
Treatment: 40 mg orally once a day -Duration of therapy: 8 weeks Maintenance: 40 mg orally once daily Comments: -If patients are not healed after 8 weeks or erosive esophagitis (EE) recurs with the oral formulation, treatment for another 8 weeks may be considered. -Controlled studies using the oral formulation for maintenance did not extend beyond 12 months. Uses: -Short-term treatment in the healing and symptomatic relief of EE -Maintenance of healing of EE.
Usual Adult Dose for Gastroesophageal Reflux Disease
Oral: 40 mg orally once a day -Duration of therapy: 8 weeks Parenteral: 40 mg via IV infusion once a day, given over at least 2 minutes OR over 15 minutes -Duration of therapy: 7 to 10 days Comments: -IV treatment should be discontinued once the patient is able to take an oral formulation. -Use of the IV formulation has not been studied for longer than 10 days. -Safety and efficacy for uses otherwise described (e.g., life-threatening gastrointestinal bleeds) are not available; however, use of this drug at 40 mg/day doses did not raise gastric pH to sufficient levels to contribute to the treatment of life-threatening conditions. -If patients are not healed after 8 weeks with the oral formulation, treatment for another 8 weeks may be considered. Uses: -Short-term treatment of gastroesophageal reflux disease (GERD) in patients with a history of erosive esophagitis -Reduction of relapse rates of daytime and nighttime heartburn symptoms in adult patients with GERD.
Usual Adult Dose for Zollinger-Ellison Syndrome
Oral: 40 mg orally 2 times a day -Maximum dose: 240 mg/day Parenteral: -Initial dose: 80 mg via IV infusion every 12 hours, given over at least 2 minutes OR over 15 minutes -Maintenance dose: 80 mg via IV infusion every 8 to 12 hours, given over at least 2 minutes OR over 15 minutes -Maximum dose: 240 mg/day -Maximum duration of therapy: 6 days Comments: -IV treatment should be discontinued once the patient is able to take an oral formulation. -Use of the IV formulation for longer than 6 days and/or with doses higher than 240 mg has not been adequately studied. -Patients may be vulnerable to increased acid production despite a short period of loss of effective inhibition. -Patients given the oral formulation should be continued on therapy for as long as clinically necessary. Uses: -Treatment of pathological hypersecretory conditions, including Zollinger-Ellison syndrome -Pathological hypersecretion conditions, including Zollinger-Ellison syndrome.
Usual Adult Dose for Pathological Hypersecretory Conditions
Oral: 40 mg orally 2 times a day -Maximum dose: 240 mg/day Parenteral: -Initial dose: 80 mg via IV infusion every 12 hours, given over at least 2 minutes OR over 15 minutes -Maintenance dose: 80 mg via IV infusion every 8 to 12 hours, given over at least 2 minutes OR over 15 minutes -Maximum dose: 240 mg/day -Maximum duration of therapy: 6 days Comments: -IV treatment should be discontinued once the patient is able to take an oral formulation. -Use of the IV formulation for longer than 6 days and/or with doses higher than 240 mg has not been adequately studied. -Patients may be vulnerable to increased acid production despite a short period of loss of effective inhibition. -Patients given the oral formulation should be continued on therapy for as long as clinically necessary. Uses: -Treatment of pathological hypersecretory conditions, including Zollinger-Ellison syndrome -Pathological hypersecretion conditions, including Zollinger-Ellison syndrome.
Usual Pediatric Dose for Erosive Esophagitis
5 years and older: 15 to less than 40 kg: 20 mg orally once a day 40 kg and greater: 40 mg orally once a day Duration of therapy: Up to 8 weeks Comment: Safety has not been established in treatment beyond 8 weeks. Uses: -Short-term treatment in the healing and symptomatic relief of EE -Short-term treatment of GERD in patients with a history of EE
Usual Pediatric Dose for Gastroesophageal Reflux Disease
5 years and older: 15 to less than 40 kg: 20 mg orally once a day 40 kg and greater: 40 mg orally once a day Duration of therapy: Up to 8 weeks Comment: Safety has not been established in treatment beyond 8 weeks. Uses: -Short-term treatment in the healing and symptomatic relief of EE -Short-term treatment of GERD in patients with a history of EE
Liver Dose Adjustments
IV: Data not available Oral: Doses over 40 mg/day have not been studied in patients with liver impairment. No adjustment recommended.
