does clindamycin change urine color

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Precautions

Does clindamycin affect urine?

Due to clindamycin achieving high concentration in the urine, it might precipitate and lead to tubular obstruction and consequent injury and hematuria [11].

What are common side effects of clindamycin?

Clindamycin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:nausea.vomiting.unpleasant or metallic taste in the mouth.joint pain.pain when swallowing.heartburn.white patches in the mouth.thick, white vaginal discharge.More items...•

Does clarithromycin discolour urine?

Serious side effects pale poo, dark pee and a yellow colour to the whites of your eyes or skin (although this may be less obvious on brown or black skin) – these can be signs of liver problems. severe pain in your stomach and/or back – this can be a sign of inflammation of the pancreas (pancreatitis)

How long does clindamycin stay in your urine?

Excretion. The average biological half-life is 2.4 hours.

What should I avoid while using clindamycin?

Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Is clindamycin a strong antibiotic?

Clindamycin is a strong broad-spectrum antibiotic, typically prescribed for serious infections, such as life-threatening methicillin-resistant Staphylococcus aureus (MRSA) skin infections.

Can antibiotics change urine color?

Medications. A number of drugs can darken urine, including the antimalarial drugs chloroquine and primaquine, the antibiotics metronidazole (Flagyl) and nitrofurantoin (Furadantin), laxatives containing cascara or senna, and methocarbamol — a muscle relaxant.

Why is my urine dark when taking antibiotics?

Dark brown or black urine has been associated with drugs such as nitrofurantoin, acetaminophen overdose, and metronidazole. While the exact mechanism is unknown, it has been hypothesized that the pigment of an azometabolite is responsible for metronidazole-induced urine discoloration.

What does it mean when your urine is dark yellow?

Dark yellow urine can be normal, but it might mean you need more fluids. When your urine appears as a darker shade of yellow, or even brown, it could be a sign that you have low urine volume.

How is clindamycin cleared from the body?

Clindamycin is excreted as biological active and biological inactive metabolites in faeces, urine and bile. Faecal excretion is predominant. About 10% of the drug is excreted in the urine as active drug and about 4% in the faeces; the remainder is excreted as inactive metabolites.

How long does it take clindamycin to work for bacterial infection?

How soon will it start working? Once you start taking clindamycin, you'll likely notice an improvement in your symptoms after a day or two. If your symptoms aren't improving at all or seem to be getting worse after taking clindamycin for a few days, follow up with your healthcare provider.

Which side effect of clindamycin causes the most concern?

This medicine may cause serious allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention.

Which side effect of clindamycin causes the most concern?

This medicine may cause serious allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention.

When do side effects of clindamycin start?

Symptoms typically appear within 30 minutes of taking a drug and can include: itchy hives and welts. swollen throat, which can cause wheezing and trouble with breathing or swallowing. chest tightness.

Does clindamycin make you feel weird?

Common side effects may include: nausea, vomiting, stomach pain; mild skin rash; or.

Why should you not lay down for 10 minutes after taking clindamycin?

by Drugs.com You should avoid lying down after taking the antibiotic clindamycin because it may slow the time it takes for the medication to move down your esophagus into your stomach, potentially causing irritation your esophagus.

What is Clindamycin Phosphate?

Clindamycin phosphate has active ingredients of clindamycin phosphate. It is often used in infection. eHealthMe is studying from 3,153 Clindamycin phosphate users for its effectiveness, alternative drugs and more.

What is Urine - Abnormal Color?

Urine - abnormal color is found to be associated with 2 conditions by eHealthMe.

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

How the study uses the data?

The study uses data from the FDA. It is based on clindamycin phosphate (the active ingredients of Clindamycin phosphate) and Clindamycin phosphate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature.

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

How long does it take for diarrhea to start after clindamycin?

Clostridium difficile associated diarrhea ( CDAD) has been reported with nearly all antibacterial agents, including clindamycin, and may range in severity from mild diarrhea to life-threatening colitis and has been observed to begin over 2 months after the administration of antibacterial agents. It is important to consider this diagnosis in ...

How long does it take for a tooth infection to show symptoms after clindamycin?

The patient's symptoms developed 2 days after initiating oral clindamycin therapy for a tooth infection. The patient's symptoms persisted despite tooth extraction and continuance of antibiotic treatment with intravenous, then oral, clindamycin.

Can pseudomembranous colitis occur after antibacterial treatment?

Frequency not reported: Esophageal ulcers, esophagitis (oral preparations) [ Ref] The onset of pseudomembranous colitis symptoms may occur during or after antibacterial treatment and is associated with the presence of Clostridium difficile toxin in the stool.

Can you stop clindamycin for colitis?

If CDAD is confirmed or suspected, antibiotic therapy not directed against Clostridium difficile may need to be discontinued. Because clindamycin therapy has been associated with severe colitis which may end fatally, it should be reserved for serious infections where less toxic antimicrobial agents are inappropriate.

Can clindamycin cause colitis?

Because clindamycin therapy has been associated with severe colitis which may end fatally, it should be reserved for serious infections where less toxic antimicrobial agents are inappropriate. Diarrhea, colitis, and pseudomembranous colitis have been observed to begin up to several weeks following cessation of therapy with clindamycin.

What happens if you give too much IV?

Cardiorespiratory arrest and hypotension have been reported after too rapid IV administration. Thrombophlebitis has been reported after intravenous infusion. [ Ref]

What are the symptoms of a cloudy urine?

cloudy urine. confusion. cough or hoarseness. dark urine. decrease in the amount of urine. diarrhea. diarrhea, watery and severe, which may also be bloody. difficulty with swallowing. dizziness.

What do I need to tell my doctor BEFORE I take Clindamycin Oral Solution?

If you have an allergy to lincomycin , clindamycin, or any other part of clindamycin oral solution.

What are some things I need to know or do while I take Clindamycin Oral Solution?

Tell all of your health care providers that you take clindamycin oral solution. This includes your doctors, nurses, pharmacists, and dentists.

How is this medicine (Clindamycin Oral Solution) best taken?

Use clindamycin oral solution as ordered by your doctor. Read all information given to you. Follow all instructions closely.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

What are the side effects of Clindamycin?

Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes. Clindamycin side effects (more detail)

What are the symptoms of an allergic reaction?

Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Joint pain or swelling.

What to do if you think you have an overdose?

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

What medications turn urine orange?

Medications. Medications that can turn urine orange include the anti-inflammatory drug sulfasalazine (Azulfidine); phenazopyridine (Pyridium); some laxatives; and certain chemotherapy drugs.

What causes a person's urine to turn red?

Beets, berries and fava beans are among the foods most likely to affect the color. Many over-the-counter and prescription medications give urine vivid tones, such as red, yellow or greenish blue. An unusual urine color can be a sign of disease. For instance, deep red to brown urine is an identifying characteristic of porphyria, a rare, ...

What causes urine to turn yellow?

Normal urine color ranges from pale yellow to deep amber — the result of a pigment called urochrome and how diluted or concentrated the urine is. Pigments and other compounds in certain foods and medications can change your urine color. Beets, berries and fava beans are among the foods most likely to affect the color.

Why is my urine red?

Red or pink urine can be caused by: Blood. Factors that can cause urinary blood (hematuria) include urinary tract infections, an enlarged prostate, cancerous and noncancerous tumors, kidney cysts, long-distance running, and kidney or bladder stones. Foods. Beets, blackberries and rhubarb can turn urine red or pink.

Why is my urine discolored?

Discolored urine that isn't the result of foods or medications could be caused by a medical condition that affects urine color. Factors that put you at risk of medical conditions that can affect urine color include: Age.

What is the system that removes waste from the body?

Causes. Your urinary system — which includes your kidneys, ureters, bladder and urethra — removes waste from your body through urine. Your kidneys, located in the rear portion of your upper abdomen, produce urine by filtering waste and fluid from your blood.

What foods make urine red?

Foods. Beets, blackberries and rhubarb can turn urine red or pink.

Why is my urine orange?

Orange. If your urine appears orange, it could be a symptom of dehydration. If you have urine that’s orange in addition to light colored stools, bile may be getting into your bloodstream because of issues with your bile ducts or liver. Adult-onset jaundice can also cause orange urine.

How is urochrome produced?

Urochrome is produced by your body breaking down hemoglobin, the protein that carries oxygen in your red blood cells. In most situations, the color of your urine will depend on how diluted this pigment is.

What causes red urine?

While urine that’s red or pink might be from something you ate recently, there are sometimes other causes. Some health conditions can cause blood to appear in your urine, a symptom known as hematuria, including: 1 enlarged prostate 2 kidney stones 3 tumors in the bladder and kidney

What does it mean when your urine is cloudy?

Cloudy. Cloudy urine can be a sign of a urinary tract infection. It can also be a symptom of some chronic diseases and kidney conditions. In some cases, cloudy urine is another sign of being dehydrated. Cloudy urine with foam or bubbles is called pneumaturia.

What does it mean when your urine turns dark brown?

If you’re getting dehydrated, you’ll notice that your urine is becoming a deep amber or even light brown. Different pigments in food you eat or medication that you take can be carried through your digestive tract and change the color of your urine.

Why is my urine dark brown?

Dark brown. In most cases, urine that’s dark brown indicates dehydration. Dark brown urine can also be a side effect of certain medications, including metronidazole (Flagyl) and chloroquine (Aralen). Eating large amounts of rhubarb, aloe, or fava beans can cause dark brown urine.

Why does my urine look red?

Urine may look red or pink if you eat fruits with naturally deep pink or magenta pigments, such as:

What causes black urine?

Here are some other potential urine colors and some of the drugs that can cause them: 1 Black-can result from taking furazolidone, Flagyl (generic name metronidazole), and other antibiotics. Aldomet (generic name methyldopa), which is used to treat high blood pressure in pregnant women, also can make urine look black because it darkens upon contact with bleach-frequently used to clean toilet bowls. 2 Purple-can be a side effect of taking phenolphthalein, a medication that has long been used as a laxative, but is falling out of favor because of concerns that it may cause cancer. 3 Green-can result from taking Robaxin (generic name methocarbamol), which is a muscle relaxant used to treat muscle spasms and Elavil (generic name amitriptyline hydrochloride), which is an antidepressant also used to treat children who wet the bed. 4 Blue-can result as a side effect of taking Dyrenium (generic name tariamterene), which is a diuretic, or by taking methylene blue, a chemical compound used in medications like Urised which seek to reduce irritation resulting from bladder infections.

What is green can?

Green-can result from taking Robaxin (generic name methocarbamol), which is a muscle relaxant used to treat muscle spasms and Elavil (generic name amitriptyline hydrochloride), which is an antidepressant also used to treat children who wet the bed.

Why does aldomet make urine black?

Aldomet (generic name methyldopa), which is used to treat high blood pressure in pregnant women, also can make urine look black because it darkens upon contact with bleach-frequently used to clean toilet bowls.

What is the difference between red and black urine?

Red urine can result, for instance, by taking drugs such as deferoxamine, which is used to treat iron poisoning or phenazopyridine, which is prescribed to treat urinary tract infection pain. Black-can result from taking furazolidone, Flagyl (generic name metronidazole), and other antibiotics.

What is blue can?

Blue-can result as a side effect of taking Dyrenium (generic name tariamterene), which is a diuretic, or by taking methylene blue, a chemical compound used in medications like Urised which seek to reduce irritation resulting from bladder infections. Show More.

Why is my urine dark?

Very dark orange, reddish or brown urine, for instance, likely has blood in it and could be a sign of infection. There are some prescription drugs, however, that can change the color of your urine simply by passing through your system. Red urine can result, for instance, by taking drugs such as deferoxamine, which is used to treat iron poisoning ...

How long does it take for an antibiotic to be eliminated?

On average it takes approximately 5 half-lives for 97% of an ingested drug to be eliminated from the body via enzymatic degredation in the liver and/or excretion via the kidneys. So assuming you are a reasonably healthy person (good liver and kidney function) then it would take around 5 or 6 half-lives. Every drug has its own half life, so it depends on what antibiotic you were taking. Also, not all drugs follow first order elimination kinetics. 95% of the drugs in use at therapeutic concentrations are eliminated by first order elimination kinetics though. A few substances are eliminated by zero-order elimination kinetics, because their elimination process is saturated. Examples are Ethanol, Phenytoin, and Salicylates. Let's assume you took a typical course of amoxicillin, which has an elimination half life of about 60 to 90 minutes. After 6 half-lives (6 to 9 hours) the drug would be out of your system. Now compare that to the antibiotic, levofloxacin, which has an elimination half life of around 6 to 8 hours. It would take around 36 to 48 hours for your body to be clear of levofloxacin. If you took a zero order kinetic drug things would potentially be more complicated because we'd have to consider saturation effects. At normal doses this isn't much of a factor though.

How does amoxicillin work?

Amoxicillin is an antibiotic which works by targeting the cell walls of bacteria. Some bacteria produce enzymes to break it down. In medicine it’s most often used to treat sinus infection, throat infection and ear infection caused by streptococci and/or staphylococci, which are susceptible. It can be part of a regimen to treat certain bacteria in the stomach (helicobacted pylori). It’s given as a pill in doses from 250 to 500 milligrams commonly. When ingested orally it is absorbed and about 10 % of it is removed by liver proteins. The rest will enter the blood stream and be eliminated by the

How long do antibiotics stay in your system?

Every antibiotic has a half life. Each half life is different. Some have 1-2 days, some have 2-3 days, some 3-4, etc. So it will depend on which antibiotic you are taking. If it has a half life of 3-4 days, you can expect it to be active in your system for 4 days max after you take the last one. And as a word of warning: When your doctor prescribes antibiotics for you, TAKE ALL OF THEM. He gives you the exact number you need to take to run the course of your illness. Saving antibiotics and taking them again is the number one reason antibiotics are losing their effectiveness to combat illnesses

How long does it take for an anti-parasitic pill to clear?

When you take a pill by mouth, it has to be absorbed, distributed, metabolized, and metabolites have to reach the target tissue in the body to elicit a therapeutic effect. Inactive metabolites are eliminated via the kidney, lungs or skin (sweat). This process takes time. It could take seconds, minutes, hours, days, months, even years for anti-parasitics. The rate of decomposition/elimination of a pill from the body is measured in half-lifes. Half-life is the time it takes for the initial concentration of a pill to decrease by half. It takes 4–5 half-lifes to clear a pill from your body. For some pills, for example, hydroxychloroquine which has a half-life of between 30–50 days. It will take around 250 days to eliminate quinine pill that you injested in the morning from your system.

How long does it take for a drug to be eliminated from the body?

On average it takes approximately 5 half-lives for 97% of an ingested drug to be eliminated from the body via enzymatic degredation in the liver and/or excretion via the kidneys. So assuming you are a reasonably healthy person (good liver and kidney function) then it would take around 5 or 6 half-lives. Every drug has its own half life, so it depends on what antibiotic you were taking. Also, not all drugs follow first order elimination kinetics. 95% of the drugs in use at therapeutic concentrations are eliminated by first order elimination kinetics though. A few substances are eliminated by ze

Why is my urine dark?

There are various reasons for dark urine. Antibiotics can cause a some coloration with one that causes an intense orange color. I cannot recall the drug and color any longer. I have seen the following colors for urine: blue, green , purple, almost black, red, pink. There may be a few other colors beyond these and the standard straw to yellow. I remember that methylene blue will cause a strong blue color to green depending on the natural yellowish color to urine. Red and pink can be cause by blood. Some of the darker more unusual colors could have been caused by old chemo-drugs that I saw back

Why does my urine turn yellow?

A number of things— your body is flushing out dead white cells, parts of the antibiotic makeup itself , and you may also be dehydrated due to the illness — even that alone will turn urine more yellow/darker.

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