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Learn More...Does ProHeart 12 treat hookworms in dogs?
At the time of the shot, ProHeart 12 also treats hookworms.* ProHeart 12 is for use in healthy dogs 12 months of age and older. *ProHeart 12 is indicated for the treatment of existing larval and adult hookworm ( Ancylostoma caninum and Uncinaria stenocephala) infections.
How long does ProHeart 12 last in dogs?
That’s why we offer ProHeart 12, a once-yearly injection to prevent heartworm disease in dogs. A single ProHeart 12 injection is an effective prevention of heartworm infection in dogs for 12 months. With just one injection, we can protect your dog from heartworm disease, hookworms, whipworm and roundworm infections.
What is ProHeart 6 used for in dogs?
ProHeart 6 Indications. ProHeart 6 is indicated for use in dogs six months of age and older for the prevention of heartworm disease caused by Dirofilaria immitis.
What is ProHeart 12 used for?
*ProHeart 12 is indicated for the treatment of existing larval and adult hookworm ( Ancylostoma caninum and Uncinaria stenocephala) infections. How much does ProHeart 12 typically cost?
How long does ProHeart 12 last?
How old is a dog when using Proheart 12?
How long does it take for heartworms to be detected in dogs?
Is ProHeart 12 safe for dogs?
Where do heartworms live in dogs?
Is heartworm a year round threat for dogs?
Is Heartgard a trademark?
See 2 more
Does ProHeart cover intestinal parasites?
Unlike most monthly chewable preventatives, ProHeart 6 does not protect against common intestinal parasites like whipworms, roundworms, and hookworms (though it does treat hookworm infections).
Does ProHeart 6 cover intestinal parasites?
ProHeart 6 does not offer protection against other common intestinal parasites like whipworm, roundworm or hookworm, although it can be used as a treatment for hookworms present at the time of administration.
Does ProHeart 12 protect against other worms?
ProHeart 12 is currently the only FDA-approved heartworm prevention product that prevents heartworm disease for a full year. It can also treat hookworms at the time of injection.
Is ProHeart a dewormer?
Moxidectin topical (brand names: Advantage Multi®, Advocate®, ProHeart®) is a topical avermectin antiparasitic that is used to prevent heartworms and treat intestinal parasites (hookworms, roundworms, and whipworms), and is combined with imidacloprid to also treat fleas.
What does ProHeart protect against?
ProHeart 6 is a medication that prevents heartworm disease in dogs 6 months of age and older. ProHeart 6 is given by injection by your veterinarian. One injection of ProHeart 6 protects your dog from heartworm disease for 6 complete months.
Does ProHeart have ivermectin?
ProHeart 6® (Moxidectin): Another Reliable Option Dogs sensitive to ivermectin—a common ingredient in monthly products for heartworm disease.
Why was ProHeart taken off the market?
In 2004, at the request of the U.S. Food and Drug Administration (FDA) Center for Veterinary Medicine (CVM), Fort Dodge Animal Health (FDAH) voluntarily recalled ProHeart 6 because of CVM's concerns regarding reports of serious ADEs in dogs following use of the drug.
How effective is ProHeart 12?
A single dose of ProHeart® 12 was 100% effective in preventing heartworm disease in dogs for a full year in both laboratory and field studies.
What heartworm prevention treats whipworms?
Interceptor Plus The main ingredient is Milbemycin Oxime which is anthelminthic. This means that in addition to acting against heartworms, it can also keep your pet safe from hookworms, whipworms, roundworms, and tapeworms.
Does Heartgard protect against intestinal parasites?
Prevent Heartworm Disease In Your Dog. HEARTGARD® Plus (ivermectin/pyrantel) prevents the invisible threat of heartworm disease and treats and controls five species of intestinal worms.
What are the side effects of ProHeart?
In field studies, the following adverse reactions were observed in dogs treated with ProHeart 6: anaphylaxis, vomiting, diarrhea (with and without blood), listlessness, weight loss, seizures, injection site pruritus, and elevated body temperature.
What is ProHeart injection for dogs?
ProHeart 6 is a twice-yearly injectable heartworm disease preventative. It's the only heartworm product that provides six months of continuous protection against heartworm disease with a single veterinary-administered dose .
Why was ProHeart taken off the market?
In 2004, at the request of the U.S. Food and Drug Administration (FDA) Center for Veterinary Medicine (CVM), Fort Dodge Animal Health (FDAH) voluntarily recalled ProHeart 6 because of CVM's concerns regarding reports of serious ADEs in dogs following use of the drug.
What are the side effects of ProHeart 6?
In field studies, the following adverse reactions were observed in dogs treated with ProHeart 6: anaphylaxis, vomiting, diarrhea (with and without blood), listlessness, weight loss, seizures, injection site pruritus, and elevated body temperature.
What is the active ingredient in ProHeart 6?
Each mL of constituted drug product contains 3.4 mg moxidectin, 3.1% glyceryl tristearate, 2.4% hydroxypropyl methylcellulose, 0.87% sodium chloride, 0.17% methylparaben, 0.02% propylparaben and 0.001% butylated hydroxytoluene. Hydrochloric acid is used to adjust pH.
Does ProHeart require heartworm test?
Administer ProHeart to healthy dogs Dogs receiving ProHeart should be tested for existing heartworms. Additional specific diagnostic tests are not required to administer ProHeart. Individual testing may be indicated by attending veterinarian to assess health status.
When to use ProHeart 6?
ProHeart 6 is indicated for use in dogs six months of age and older for the prevention of heartworm disease caused by Dirofilaria immitis.
How many vials of Proheart 6?
ProHeart 6 (moxidectin) for extended-release injectable suspension consists of two separate vials: One vial contains 10% moxidectin sterile microspheres and the second vial contains a specifically formulated sterile vehicle for constitution with the microspheres. No other diluent should be used. A clear or translucent appearance of the vehicle is normal. Each mL of constituted drug product contains 3.4 mg moxidectin, 3.1% glyceryl tristearate, 2.4% hydroxypropyl methylcellulose, 0.87% sodium chloride, 0.17% methylparaben, 0.02% propylparaben and 0.001% butylated hydroxytoluene. Hydrochloric acid is used to adjust pH.
How long does it take for moxidectin to show up in blood after ProHeart 6?
Following injection with ProHeart 6, peak moxidectin blood levels will be observed approximately 7-14 days after treatment. At the end of the six month dosing interval, residual drug concentrations are negligible. Accordingly, little or no drug accumulation is expected to occur with repeated administrations.
What is moxidectin in heartworm?
Moxidectin is a pentacyclic 16-membered lactone macrolide. Moxidectin has activity resulting in paralysis and death of affected parasites. The stage of the canine heartworm affected at the recommended dose rate of 0.17 mg moxidectin/kg body weight is the tissue larval stage.
Is ProHeart 6 contraindicated?
ProHeart 6 is contraindicated in animals previously found to be hypersensitive to this drug.
Can ProHeart 6 be given to dogs?
Caution should be used when administering ProHeart 6 to heartworm positive dogs (see ADVERSE REACTIONS ).
Why is heartworm on the rise in dogs?
This increase is mainly due to transport of dogs throughout the country, changes in climate conditions, and less than 25% of dogs in our area receiving heartworm prevention. With heartworm disease on the rise, prevention is a must for your dog.
Does LVC offer heartworm prevention?
LVC is proud to now offer ProHeart 12 to our patients as a new option for heartworm prevention ! ProHeart 12 is the only once-yearly injection to prevent heartworm disease and intestinal parasites in dogs.
Where can I find resources about ProHeart products to share with my staff and clients?
Our Practice Resources provide a wide variety of print and social media resources and tools for you, your staff, and pet owners to help ensure practice success.
What is the efficacy of ProHeart 12?
In 3 studies, PROHEART 12 was 100% effective against heartworm disease* for one year. Learn more about efficacy.
What is the difference between ProHeart 12 and ProHeart 6?
ProHeart 12 delivers a full year of heartworm disease prevention with just 1 veterinary-administered injection. ProHeart 6 offers continuous protection against heartworm disease with 2 injections per year.
How old is a dog to take Proheart 6?
IMPORTANT SAFETY INFORMATION: Use PROHEART 6 in dogs 6 months of age or older and PROHEART 12 in dogs 12 months of age or older. Do not administer to dogs that are sick, debilitated, underweight, have a history of weight loss, or to those previously found to be hypersensitive to the drug.
Does Zoetis work with ProHeart?
Zoetis will work with you to ensure that you and your clients are satisfied with the performance of ProHeart or we will refund you the purchase price.*
Does ProHeart MOA work?
The unique ProHeart MOA is constantly working to prevent heartworm disease in dogs, and works continuously vs short-term monthly chewables. Slow-dissolving microspheres contain and prolong the effects of moxidectin–which redistributes from plasma to adipose tissue. The adipose tissue acts as a reservoir, allowing efficacy. See ProHeart MOA.
Are ProHeart products safe in special populations?
ProHeart 12 has been evaluated and found safe in female reproducing dogs and their offspring, male reproduc ing dogs, ivermectin-sensitive Collies, or Heartworm-positve dogs and dogs ≥ 12 months of age. Learn more.
What is ProHeart 12 for dogs?
That’s why we offer ProHeart 12, a once-yearly injection to prevent heartworm disease in dogs.
How long does ProHeart 12 last?
A single ProHeart 12 injection is an effective prevention of heartworm infection in dogs for 12 months. With only 1 injections, protect your dog from heartworm disease, hookworms, whipworm and roundworm infections.
How are intestinal parasites treated?
For a pinworm infection, there are over-the-counter and prescription antiworm medicines. Treatment requires two doses spaced two weeks apart. In most cases, household members and caretakers will need treatment at the same time as the infected child. This helps prevent reinfection and spreading of the infection. Strict hygiene is necessary until all doses are complete.
What are the potential complications of intestinal parasites?
However, people with weakened immune systems can develop life-threatening complications from intestinal parasites. This includes severe dehydration, malnutrition, dangerous weight loss, and spread to other areas of the body, such as the respiratory tract.
What are the symptoms of intestinal parasites?
Intestinal parasites can live in the body and not cause any noticeable problems or very mild symptoms. On the other hand, some intestinal parasite infections can cause symptoms that are quite severe.
What are the most common parasites in the United States?
The other type of intestinal parasites in humans is protozoa. In the United States, the most common protozoa infections are Giardia lamblia, Entamoeba histolytica, Cryptosporidium, and Cyclospora cayetanensis.
Why are intestinal parasites so common?
Intestinal parasites are very common in developing countries. Lack of adequate sanitation in these countries is the main reason for this. In industrialized countries, including the United States, they aren’t as common. However, they can still be problematic in certain populations. For example, experts estimate that about 13% of the American population has pinworms. Children are most likely to have this parasite and pass it to household members and caregivers.
How do you get giardia?
Ingesting the microscopic cysts or the parasites themselves causes infection. You can also get the giardia parasite through anal sex. There are two main types of intestinal parasites that infect humans. The first is helminths.
How long does it take for a protozoal infection to go away?
Protozoal intestinal infections may or may not require treatment. When the infection is mild, it may go away on its own within a few weeks in healthy people. Severe or persistent infections often require medications, as do infections in people with weakened immune systems.
How long does ProHeart 12 last?
ProHeart 12 provides 1 full year of heartworm disease prevention in just 1 shot. The active ingredient, moxidectin, is contained in slow-dissolving microspheres that are stored in your dog’s fat-storing connective tissue (a.k.a. adipose tissue). The medicine is then released evenly over 1 year’s time, keeping your buddy consistently protected from heartworms. Cool, right?
How old is a dog when using Proheart 12?
IMPORTANT SAFETY INFORMATION: Use ProHeart 6 in dogs 6 months of age or older and ProHeart 12 in dogs 12 months of age or older.
How long does it take for heartworms to be detected in dogs?
The heartworms then mature inside your dog, living in major vessels around the heart and even sometimes inside the heart itself. It could take longer than 7 months for the heartworms to be detectable with routine testing.
Is ProHeart 12 safe for dogs?
In three well-controlled studies, ProHeart 12: 2. Was 100% effective against heartworm disease* in dogs. Was demonstrated to be safe for most types of dogs over 12 months, including: Reproducing dogs. Collies sensitive to ivermectin—a common ingredient in monthly heartworm products.
Where do heartworms live in dogs?
The heartworms then mature inside your dog, living in major vessels around the heart and even sometimes inside the heart itself.
Is heartworm a year round threat for dogs?
It can be tough to remember monthly medications for your dog, and heartworm disease is a year-round threat.
Is Heartgard a trademark?
Heartgard is a registered trademark of Boehringer Ingelheim.
Description
Pharmacology
- Moxidectin is a semi-synthetic methoxime derivative of nemadectin which is a fermentation product of Streptomyces cyaneogriseussubspecies noncyanogenus. Moxidectin is a pentacyclic 16-membered lactone macrolide. Moxidectin has activity resulting in paralysis and death of affected parasites. The stage of the canine heartworm affected at the recommended dose rate …
Proheart 6 Indications
- ProHeart 6 is indicated for use in dogs six months of age and older for the prevention of heartworm disease caused by Dirofilaria immitis. ProHeart 6 is indicated for the treatment of existing larval and adult hookworm (Ancylostoma caninum and Uncinaria stenocephala)infections.
Proheart 6 Dosage and Administration
- Owners should be given the Client Information Sheet for ProHeart 6 to read before the drug is administered and should be advised to observe their dogs for potential drug adverse events including those described in the sheet. The Client Information Sheet is attached to this package insert and available online at http://www.proheart6.com/ for reprinting to provide to the owner. P…
Information For Dog Owners
- Always provide Client Information Sheet and review with owners before administering ProHeart 6. Owners should be advised of the potential for adverse reactions, including anaphylaxis, and be informed of the clinical signs associated with drug toxicity (see WARNINGS, PRECAUTIONS and ADVERSE REACTIONSsections.) Owners should be advised to contact their veterinarian immedi…
Human Warnings
- Not for human use. Keep this and all drugs out of the reach of children. May be slightly irritating to the eyes. May cause slight irritation to the upper respiratory tract if inhaled. May be harmful if swallowed. If contact with the eyes occurs, rinse thoroughly with water for 15 minutes and seek medical attention immediately. If accidental ingestion occurs, contact a Poison Control Center o…
Warnings
- ProHeart 6 should be administered with caution in dogs with pre-existing allergic disease, including food allergy, atopy, and flea allergy dermatitis. In some cases, anaphylactic reactions have resulted in liver disease and death. Anaphylactic and anaphylactoid reactions should be treated immediately with the same measures used to treat hypersensitivity reactions to vaccine…
Precautions
- Caution should be used when administering ProHeart 6 concurrently with vaccinations. Adverse reactions, including anaphylaxis, have been reported following the concomitant use of ProHeart 6 and vaccinations (see WARNINGS). Prior to administration of ProHeart 6, the health of the patient should be assessed by a thorough medical history, physical examination and diagnostic testing …
Adverse Reactions
- In field studies, the following adverse reactions were observed in dogs treated with ProHeart 6: anaphylaxis, vomiting, diarrhea (with and without blood), listlessness, weight loss, seizures, injection site pruritus, and elevated body temperature. Dogs with clinically significant weight loss (>10%) were more likely to experience a severe adverse reaction. In a laboratory effectiveness st…
Animal Safety
- General Safety: ProHeart 6 has been administered to a wide variety of healthy dogs six months of age and older, including a wide variety of breeds, pregnant and lactating females, breeding males, and ivermectin-sensitive collies. In clinical studies, two geriatric dogs with a history of weight loss after the initial ProHeart 6 injection died within a month of the second 6 month injection. A third …