does protonix interfere with other medications

Precautions

Protonix injection contains edetate disodium which can chelate metal ions, including zinc. Consider zinc supplementation in patients prone to zinc deficiency who are treated with Protonix IV. May interact with some other medications including antivirals used to treat HIV, methotrexate, and sometimes warfarin.

Does Protonix interact with other medications?

You should not use this medicine if:

• you also take medicine that contains rilpivirine (Edurant, Complera, Juluca, Odefsey);
• if you had breathing problems, kidney problems, or a severe allergic reaction after taking pantoprazole in the past;
• you are allergic to pantoprazole or similar medicines (lansoprazole, omeprazole, Nexium, Prevacid, Prilosec, and others).

What meds should avoided when taking pantoprazole?

Plavix can interact negatively with several prescription and over-the-counter medications, chiefly blood thinners. Before going on Plavix, be sure to inform your doctor if you are taking any other medication that may thin the blood or prevent clotting.

Does Plavix interact with other medications?

Pantoprazole is generally safe for long-term use under a doctor’s supervision. But there are potential concerns, such as an increased risk of fractures. The best approach is to use the lowest pantoprazole dosage for the shortest amount of time necessary. Ongoing use may be appropriate when the benefits outweigh the risks.

Is it safe to take pantoprazole for a long time?

What medications should not be taken with Protonix?

Pantoprazole decreases stomach acid, so it may change how well these products work. Some affected products include ampicillin, atazanavir, erlotinib, levoketoconazole, nelfinavir, pazopanib, rilpivirine, certain azole antifungals (itraconazole, ketoconazole, posaconazole), among others.

Is it OK to take Protonix with other meds?

Blood, urine, and other laboratory tests may be needed to check for unwanted effects. Do not use pantoprazole together with medicines containing rilpivirine (eg, Complera®, Edurant®, Odefsey®). Using these medicines together may cause unwanted side effects.

Can I take other meds at the same time as pantoprazole?

Do not take other medicines unless they have been discussed with your doctor. This includes prescription (eg, atazanavir, nelfinavir, Reyataz®, Viracept®) or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Can you take Protonix with blood pressure medicine?

No interactions were found between lisinopril and Protonix.

What are the dangers of taking pantoprazole?

Taking pantoprazole for more than a year may increase your chances of certain side effects, including: bone fractures. gut infections. vitamin B12 deficiency – symptoms include feeling very tired, a sore and red tongue, mouth ulcers and pins and needles.

What is the most common side effect of Protonix?

The most common side effects of PROTONIX in adults include: headache, diarrhea, nausea, stomach-area (abdominal) pain, vomiting, gas, dizziness, and joint pain.

Can you take vitamin D while taking pantoprazole?

No interactions were found between pantoprazole and Vitamin D3.

How long should you wait to eat after taking Protonix?

Protonix oral granules should be taken 30 minutes before a meal; sprinkle directly onto one teaspoonful of applesauce or apple juice, stir and swallow straight away. Swallow delayed-release tablets whole; do not crush or chew. Usually taken once a day.

What happens if I take pantoprazole after eating?

Pantoprazole can be taken before or after food, although taking it before food is preferable. If you forget to take a dose at your usual time, you can take it when you remember (unless it is nearly time for your next dose, in which case leave out the missed dose).

Does Protonix affect blood pressure?

Omeprazole, lansoprazole and pantoprazole had no effect on blood pressure and electrocardiogram of anesthetized rat. Pharmacol Res.

What is the safest drug for acid reflux?

Proton pump inhibitors are accepted as the most effective initial and maintenance treatment for GERD. Oral pantoprazole is a safe, well tolerated and effective initial and maintenance treatment for patients with nonerosive GERD or erosive esophagitis.

Does Protonix cause weight gain?

You may have weight gain while you're taking pantoprazole oral tablets. Both weight gain and weight loss were reported after the drug's initial studies were done. Additionally, you may gain weight if you have edema (swelling) or bloating, which are possible side effects of pantoprazole.

What is the best time to take pantoprazole?

Usually taken once daily. Swallow tablets whole; do not split, crush, or chew. Pantoprazole is best taken before breakfast or 30 to 60 minutes before a meal. If administering twice daily take the first dose before breakfast and the second dose before dinner.

Can I take vitamin D with pantoprazole?

No interactions were found between pantoprazole and Vitamin D3.

How long does it take for pantoprazole to work for acid reflux?

You should start to feel better within 2 to 3 days. It may take up to 4 weeks for pantoprazole to work properly. You may still have symptoms during this time.

Can you take vitamins with pantoprazole?

Interactions between your drugs If you are iron-deficient or have anemia, you should talk to your doctor before using multivitamin, prenatal together with pantoprazole. By reducing stomach acid, pantoprazole may reduce the absorption of iron and make multivitamin, prenatal less effective in treating your condition.

How long does it take for Protonix to peak?

Peak effects happen within two and a half hours and start to decline after 12 hours although may last for over 24 hours. 7. Interactions. Medicines that interact with Protonix may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with Protonix.

What is Protonix 2021?

Medically reviewed by Carmen Fookes, BPharm. Last updated on March 29, 2021. 1. How it works. Protonix is a brand (trade) name for pantoprazole. Pantoprazole works by reducing the production of stomach acid by irreversibly blocking the actions of an enzyme responsible for acid production, ...

How does pantoprazole work?

Pantoprazole works by reducing the production of stomach acid by irreversibly blocking the actions of an enzyme responsible for acid production, called H+/K+ ATPase (also known as the gastric proton pump). The proton pump is located in the parietal cells of the stomach wall.

What medications interact with Protonix?

Common medications that may interact with Protonix include: aminophylline or theophylline. ampicillin.

What class is Protonix?

Protonix belongs to the class of medicines known as proton pump inhibitors (PPIs).

Which medications rely on a certain gastric pH for absorption?

medications that rely on a certain gastric pH for absorption, such as ampicillin, dasatinib, erlotinib, iron salts, ketoconazole/itraconazole, mycophenolate mofetil, or nilotinib

What are the symptoms of low magnesium?

Seek urgent medical advice if you have severe stomach pain, nausea, vomiting, diarrhea, seizures, blood in the urine, or urinating more frequently, or symptoms of low magnesium (confusion, dizziness, tremors, muscle spasms, abnormal heart rate).

How does Protonix work?

Protonix, like all proton pump inhibitors, works by suppressing gastric acid secretion by inhibiting the gastric (H+,K+)-ATPase enzyme pump. The antisecretory effects persist for more than 24 hours, which allows for once-daily dosing in most cases.

What are the interactions between Protonix and other drugs?

Other major interactions include drugs that rely on a certain stomach pH, like ampicillin.

What is the PPI for pantoprazole?

Overview. Protonix ( pantoprazole) is a PPI (proton pump inhibitor) used to treat: Protonix, like all proton pump inhibitors, works by suppressing gastric acid secretion by inhibiting the gastric (H+,K+)-ATPase enzyme pump.

How to take Protonix?

Although Protonix can be taken with most other medications, for optimal effect, most guidelines recommend Protonix to be taken as follows: 1 Take on an empty stomach, 30-60 minutes before meals. 2 Swallow whole. Do not chew, crush, or split the tablet.

Can you take Protonix at the same time?

Therefore, it may be recommended to take Protonix at the same time as some of your other medication , which is safe in most situations.

Severe Interactions

These medications are not usually taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

Serious Interactions

These medications may interact and cause very harmful effects. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

Moderate Interactions

These medications may cause some risk when taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

What is protonix used for?

Protonix (pantoprazole sodium) is a drug in a class of powerful acid-suppressing medications called proton pump inhibitors (PPIs). These medicines can cause rare but life-threatening side effects. Protonix is one of several PPIs named in lawsuits over serious kidney conditions. By Terry Turner. Edited By Emily Miller.

How long does Protonix last?

Doctors may also prescribe Protonix for long-term use to treat excess stomach acid. Long-term treatment is anything lasting more than eight weeks. There is no research on the effects of taking Protonix for more than 12 months.

What is the generic name for Protonix?

The generic name for Protonix is pantoprazole. Pfizer’s patent on pantoprazole ran out in 2010. The FDA approved the first generic versions of pantoprazole that same year. The agency has approved several generic pantoprazole applications since then. All generic versions require a prescription.

What is PRN in medical?

PRN is a nationally recognized leader in providing independent medical reviews. Reviewer specialties include internal medicine, gastroenterology, oncology, orthopedic surgery and psychiatry. Protonix (pantoprazole sodium) is a proton pump inhibitor (PPI). PPIs are powerful medications that block the production of acid in the stomach.

What are the side effects of Protonix?

Less Serious Side Effects of Protonix. Headache. Diarrhea.

Can Protonix cause false positives?

Protonix can also cause false positives in drug tests for marijuana use.

Is Protonix still taking cases?

Protonix lawyers are still taking new cases. They expect to file thousands more PPI lawsuits before the first case goes to trial.

What is Protonix?

Protonix (pantoprazole) is a proton pump inhibitor that decreases the amount of acid produced in the stomach.

How should I use Protonix?

Take Protonix exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What other drugs will affect Protonix?

Tell your doctor about all your other medicines. Some may interact with pantoprazole, especially:

What are the side effects of pantoprazole?

severe stomach pain, diarrhea that is watery or bloody; sudden pain or trouble moving your hip, wrist, or back; bruising or swelling where intravenous pantoprazole was injected; kidney problems - fever, rash, nausea, loss of appetite, joint pain, urinating less than usual, blood in your urine, weight gain;

How is Protonix taken?

Protonix is taken by mouth (oral) or given as an infusion into a vein (injection). A healthcare provider may teach you how to properly use the injection by yourself.

What does it mean when you have diarrhea?

Diarrhea may be a sign of a new infection. Call your doctor if you have diarrhea that is watery or has blood in it.

What are the interactions between PPI and other drugs?

PPI Drug Interactions. Proton pump inhibitor drug interactions can happen with medicines ranging from aspirin to cancer drugs. People should be aware of how proton pump inhibitors interact with other drugs they take. PPIs alter the pH of the stomach. The pH is a measure of stomach acidity.

How long should I wait to take Zantac after taking H2 blocker?

Doctors may recommend taking the PPI in the morning and the H2 blocker in the afternoon or evening. People should wait four to 12 hours after taking an H2 blocker before taking their next PPI. Learn More About Zantac.

How does H2 blocker work?

H2 blockers block signals telling the stomach to produce acid. PPIs work later in the acid-making process. They prevent tiny pumps from producing the acid. But H2 blockers can decrease PPIs’ effects if people take them too closely together.

How does pH affect drugs?

An altered pH can change the way certain drugs work within the body. It can affect the way the body absorbs or filters them. It can also change the way the body activates certain drugs. Not all PPIs have the same drug interactions. Doctors may recommend a different PPI if a patient is taking certain other medicines.

How many drugs can cause a reaction to a proton pump inhibitor?

Proton pump inhibitor (PPI) interactions can occur with at least 290 medicines. These other drugs come in both brand name and generic versions. They add up to more than 1,800 different products. At least 20 of these drugs can cause a severe reaction if taken with certain PPIs.

What is a PPI?

Proton Pump Inhibitors (PPI) Interactions. People who take proton pump inhibitors (PPIs) may need to limit or avoid their exposure to certain medicines or foods due to potential interactions. Patients should discuss all medications and supplements they are taking, as well as any dietary restrictions, with their doctor prior to taking a PPI.

What drugs affect metabolism?

Diazepam (benzodiazepine – anxiety. Coumadin, Jantoven (warfarin) – blood thinners. Celexa (citalopram) – Depression. Dilantin, Phenytek (phenytoin) - seizures. Omeprazole affects metabolism with these drugs. It blocks the body’s ability to eliminate them. That allows them to build up in the blood stream.

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