What are the most common side effects of Revlimid?
Serious side effects from Revlimid aren’t common, but they can occur. Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Liver failure. Symptoms can include: jaundice (yellowing of your skin and the whites of your eyes)
Does Revlimid cause atrial fibrillation?
In clinical studies, 7% of people with multiple myeloma taking Revlimid for the first time had atrial fibrillation. In this same group, 1.4% of people with multiple myeloma taking Revlimid had heart attacks.
Can Revlimid be used to treat cancer?
Revlimid is FDA-approved to treat people with myelodysplastic syndromes (a type of cancer in your blood). However, Revlimid should only be used by people who also have red blood cell (RBC) transfusion-dependent anemia. People with anemia don’t have enough red blood cells.
Is Revlimid dangerous for multiple myeloma?
2% of people with multiple myeloma taking Revlimid after receiving at least one past treatment with a different drug Febrile neutropenia can be dangerous. High fever can lead to symptoms such as headaches, weakness, and severe infections. In some cases, it can even cause death.
What are the long term effects of Revlimid?
It's possible that Revlimid can cause long-term side effects. For example, this medication may cause: liver problems, such as liver failure. other types of cancer, such as skin cancer or leukemia.
Can Revlimid cause heart palpitations?
Revlimid can cause heart problems such as atrial fibrillation (irregular heartbeat). These problems are more common in people taking Revlimid to treat multiple myeloma.
How long can a person take Revlimid?
You'll take this dosage on days 1 through 21 of a 28-day cycle. You won't take the drug on days 22 to 28. Revlimid can be taken for up to 12 cycles. Your doctor will likely prescribe Revlimid with the medication rituximab (Truxima, Rituxan).
What does Revlimid do to your body?
Treatment with REVLIMID can cause swelling of the limbs (arms, hands, and feet) and skin, called edema. This swelling or puffiness of the tissue directly under your skin is caused by excess fluid trapped in your body's tissues. Edema is most commonly noticed in the hands, arms, feet, ankles, and legs.
Is there an alternative to Revlimid?
Thalomid may be a good alternative to Revlimid for patients with low blood cell counts.
How effective is Revlimid in treating multiple myeloma?
Revlimid did not improve the survival rates in the overall population, with 78.6% of patients living past the three-year mark, compared with 75.8% of those in the observation group. However, patients who received a stem cell transplant lived significantly longer on Revlimid than with observation only, with 87.
What foods should I avoid with multiple myeloma?
Since medications used to treat multiple myeloma often cause nausea and vomiting, avoid foods that are spicy and fried. Avoid foods with strong odors. Instead, choose foods that are at room temperature and bland such as crackers, cheese, canned fruit, yogurt, toast, potatoes, rice, and pasta. Choose protein-rich foods.
Who should not take Revlimid?
REVLIMID should not be used to treat people who have chronic lymphocytic leukemia (CLL) unless they are participants in a controlled clinical trial. It is not known if REVLIMID is safe and effective in children under 18 years of age.
Is Revlimid considered a chemo drug?
Immunomodulating drugs (IMiDs) like lenalidomide (Revlimid), pomalidomide (Pomalyst), and thalidomide (Thalomid) help your immune system fight the cancer. They're given in capsules. After chemotherapy, your doctor may still want you to take low doses of these to keep new tumors from growing.
Can multiple myeloma affect the heart?
Common manifestations of multiple myeloma include osteolytic lesions, cytopenias, hypercalcemia, and renal insufficiency. Patients may also exhibit heart failure which is often associated with either past therapy or cardiac amyloidosis. A less recognized mechanism is high-output heart failure.
What is the best maintenance drug for multiple myeloma?
REVLIMID is the only multiple myeloma treatment FDA approved for maintenance therapy after an auto-HSCT. Clinical trials include 2 studies of REVLIMID as a maintenance therapy after an auto-HSCT.
Can revlimid cause weight gain?
Lenalidomide may cause a serious type of reaction called tumor lysis syndrome. Call your doctor right away if you have a decrease or change in urine amount, joint pain, stiffness, or swelling, lower back, side, or stomach pain, a rapid weight gain, swelling of the feet or lower legs, or unusual tiredness or weakness.
Does Revlimid cause anxiety?
Difficulty sleeping; depression; anxiety; feeling of confusion. Back pain; muscle spasms; muscle and/or joint pain; swollen joints; bone pain; muscular weakness; fall.
Does Revlimid cause high blood pressure?
In 100 people receiving Velcade, Revlimid, Dexamethasone, more than 20 and up to 100 may have: High blood pressure which may cause headaches, dizziness. Skin changes, rash, acne. Swelling of the body, bruising.
What are the side effects of taking lenalidomide?
Lenalidomide may cause a serious type of reaction called tumor lysis syndrome. Call your doctor right away if you have a decrease or change in urine amount, joint pain, stiffness, or swelling, lower back, side, or stomach pain, a rapid weight gain, swelling of the feet or lower legs, or unusual tiredness or weakness.
When is the best time to take Revlimid?
REVLIMID is an oral medication taken once daily at about the same time each day, with or without food: You can take REVLIMID at home or wherever you choose. The recommended starting dose of REVLIMID is 25 mg/day for 21 days of a 28-day cycle; your doctor will tell you which dose is right for you.
How to know if you have a heart attack with Revlimid?
Call your healthcare provider or get medical help right away if you get any of the following during treatment with REVLIMID: Signs or symptoms of a heart attack may include: chest pain that may spread to the arms, neck, jaw, back, or stomach area (abdomen), feeling sweaty, shortness of breath, feeling sick or vomiting.
What are the symptoms of a severe allergic reaction to Revlimid?
Call your healthcare provider right away if you develop any of these signs or symptoms of a severe allergic reaction or severe skin reaction during treatment with REVLIMID: a red, itchy skin rash. peeling of your skin or blisters. severe itching. fever.
What to tell your healthcare provider before taking Revlimid?
Before taking REVLIMID, tell your healthcare provider: If you have had a blood clot in the past; If you have high blood pressure, smoke, or if you have been told you have a high level of fat in your blood (hyperlipidemia); and. About all the medicines you take.
Is Revlimid a prescription?
REVLIMID ® (lenalidomide) is a prescription medicine, used to treat adults with multiple myeloma (MM) in combination with the medicine dexamethasone, or as maintenance treatment after autologous hematopoietic stem cell transplantation (a type of stem cell transplant that uses your own stem cells). REVLIMID should not be used to treat people who have chronic lymphocytic leukemia (CLL) unless they are participants in a controlled clinical trial. It is not known if REVLIMID is safe and effective in children.
Can you stop Revlimid?
These are not all of the possible side effects of REVLIMID. Your healthcare provider may adjust your dose or have you temporarily or permanently stop taking REVLIMID if you develop certain serious side effects. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Can you donate sperm while taking Revlimid?
Do not donate sperm while taking REVLIMID, during any breaks (interruptions) in your treatment, and for 4 weeks after stopping REVLIMID. If a female becomes pregnant with your sperm, the baby may be exposed to REVLIMID and may be born with birth defects.
Can you use condoms with Revlimid?
Males, including those who have had a vasectomy, must always use a latex or synthetic condom during any sexual contact with a pregnant female or a female that can become pregnant while taking REVLIMID, during any breaks (interruptions) in your treatment with REVLIMID, and for up to 4 weeks after stopping REVLIMID.
Can you stop taking Revlimid?
Your healthcare provider may tell you to decrease your dose, temporarily stop or permanently stop taking REVLIMID if you develop certain serious side effects during treatment with REVLIMID. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Does Revlimid cause rash?
Rash is another common side effect of REVLIMID. Rash may range in severity from mild irritation to obvious changes in skin color. Some patients have had serious skin reactions that required immediate medical attention or were fatal. If you get any kind of rash, tell your healthcare provider immediately.
Can Revlimid cause shortness of breath?
Treatment with REVLIMID can cause shortness of breath. If you experience a shortness of breath, you are not able to get enough air into your lungs. If you have shortness of breath, tell your doctor or nurse. He or she will want to know about any side effects you may have.
Is Revlimid a prescription?
Common Side Effects. REVLIMID ® (lenalidomide) is a prescription medicine, used to treat adults with multiple myeloma (MM) in combination with the medicine dexamethasone, or as maintenance treatment after autologous hematopoietic stem cell transplantation (a type of stem cell transplant that uses your own stem cells).
Can Revlimid be taken in breast milk?
It is not known if REVLIMID passes into your breast milk and can harm your baby. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. REVLIMID and other medicines may affect each other, causing serious side effects.
Does Revlimid cause side effects?
Along with its needed effects, lenalidomide (the active ingredient contained in Revlimid) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Does lenalidomide need immediate medical attention?
Side effects not requiring immediate medical attention. Some side effects of lenalidomide may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine.
Can lenalidomide cause birth defects?
Lenalidomide may cause birth defects or embryo fetal death and should not be used during pregnancy. Exclude pregnancy before starting treatment with 2 negative pregnancy tests. Prevent pregnancy with abstinence or 2 reliable contraception methods, during treatment and for 4 weeks after treatment.
Is lenalidomide used for multiple myeloma?
Risk of venous and arterial thromboembolism ( DVT, pulmonary embolism, myocardial infarction, and stroke) is significantly increased in patients with multiple myeloma who are treated with lenalidomide and dexamethasone therapy. Thromboprophylaxis is recommended and should be based on underlying risks.
What does Revlimid do?
Revlimid can stop cancer cells from multiplying, which stops the progression (worsening) of cancer. Revlimid can also cause existing cancer cells to die.
What is Revlimid a brand name?
Lenalidomide is similar to a drug called thalidomide, so Revlimid is called a thalidomide analogue.
Can I take Revlimid if I’m going to have surgery?
Yes, you can. However, Revlimid may raise your risk of getting infections after the surgery. If you need to have surgery, tell your doctor that you’re taking Revlimid. They can prescribe antibiotics to help lower your risk of getting infections after surgery.
Can Revlimid cause other cancers to occur?
It’s possible. In clinical studies, people who took Revlimid had a higher risk of developing new cancers. This included leukemia, myelodysplastic syndromes, and skin cancer.
Can I take Revlimid while pregnant?
No, pregnant women should not take Revlimid. It can cause miscarriages and severe birth defects.
Do I have to register for the Revlimid REMS program?
Yes. Revlimid is only prescribed to people who enroll in the Revlimid Risk Evaluation and Mitigation Strategy (REMS) program. This program’s purpose is to help prevent serious risks to fetuses and to help prevent birth defects. People who enroll in the Revlimid REMS program must meet certain requirements before they can be prescribed Revlimid.
Do I need prior authorization to get Revlimid?
Probably. Many health insurers require prior authorization (preapproval) before agreeing to cover Revlimid. Your doctor must request prior authorization on your behalf. Once your insurance company approves coverage for Revlimid, your doctor will let you know when you can start taking it.
What is Revlimid?from ehealthme.com
Revlimid has active ingredients of lenalidomide. It is often used in multiple myeloma. eHealthMe is studying from 281,503 Revlimid users for its effectiveness, alternative drugs and more.
How long does it take to take Revlimid?from revlimid.com
inside of your eyes, nose, or mouth, flush well with water. If you miss a dose of REVLIMID and it has been less than 12 hours since your regular time, take it as soon as you remember.
What to do when serious adverse effects are detected in your trial?from ehealthme.com
When serious adverse effects are detected in your trial, your doctor will be notified to check them out promptly. What you need to do:#N#1. start your phase IV clinical trial#N#2. ask your doctor to join eHealthMe professional network
Is Revlimid safe for children?from revlimid.com
REVLIMID should not be used to treat people who have chronic lymphocytic leukemia (CLL) unless they are participants in a controlled clinical trial. It is not known if REVLIMID is safe and effective in children. WARNING: Risk to unborn babies, risk of low blood counts and blood clots.
What are the symptoms of a blood clot in the lung?from revlimid.com
Call your healthcare provider or get medical help right away if you get any of the following during treatment with REVLIMID: Signs or symptoms of a blood clot in the lung, arm, or leg may include:shortness of breath, chest pain, or arm or leg swelling.
Is Revlimid a lenalidomide?from ehealthme.com
Revlimid has active ingredients of lenalidomide. It is often used in multiple myeloma. eHealthMe is studying from 256,016 Revlimid users for its effectiveness, alternative drugs and more.
Can Revlimid be taken in breast milk?from revlimid.com
It is not known if REVLIMID passes into your breast milk and can harm your baby. Tell your healthcare provider about all the medicines you take,including prescription and over-the-counter medicines, vitamins, and herbal supplements. REVLIMID and other medicines may affect each other, causing serious side effects.
What is Revlimid?
Revlimid has active ingredients of lenalidomide. It is often used in multiple myeloma. eHealthMe is studying from 281,511 Revlimid users for its effectiveness, alternative drugs and more.
What is Cardiotoxicity?
Cardiotoxicity (damage to the heart muscle) is found to be associated with 687 drugs and 451 conditions by eHealthMe.
How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
How the study uses the data?
The study uses data from the FDA. It is based on lenalidomide (the active ingredients of Revlimid) and Revlimid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature.
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
How many people with multiple myeloma have DVT?
7% to 9% of people with multiple myeloma had DVT while taking Revlimid after receiving at least one past treatment with a different drug
Can you get fatigued while taking Revlimid?
You might experience fatigue (a lack of energy) while taking Revlimid. In most cases, fatigue isn’t considered a serious condition.
Can Revlimid cause side effects?
Serious side effects. Serious side effects from Revlimid aren’t common, but they can occur. Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency.
Does revlimid kill MM?
Unfortunately, maintenance revlimid can also bring side effects. Only the patient can decide if the risk of discontinuing maintenance chemo is worth the risk of stoping chemo. One possible solution for may be evidence-based but non-toxic therapies shown to kill MM. All have been shown to fight MM.
Does relimid rash go away?
For many people, the skin rash is mild and goes away on its own. However, in some people, the rash is severe or doesn’t go away. A rash can be a symptom of a more serious side effect from Revlimid.
Is lenalidomide maintenance therapy good for survival?
A beneficial effect of lenalidomide maintenance therapy on overall survival in this setting has been inconsistent between individual studies.
Does revlimid cause a rash?
For many people, the skin rash is mild and goes away on its own. However, in some people, the rash is severe or doesn’t go away. A rash can be a symptom of a more serious side effect from Revlimid. Tell your doctor if you have a skin rash after taking Revlimid.
How much revlimid is in a pill?
Revlimid comes in the following strengths: 2.5 milligrams (mg), 5 mg, 10 mg, 15 mg, 20 mg, and 25 mg. Your doctor will recommend the best strength for you to take based on your condition.
What to do if you have side effects from Revlimid?
If you develop serious side effects while taking Revlimid, call your doctor right away . If the side effects seem life threatening or you think you’re having a medical emergency, immediately call 911 or your local emergency number .
Does stopping Revlimid treatment cause withdrawal symptoms?
No, stopping Revlimid treatment doesn’t cause withdrawal symptoms. Withdrawal symptoms weren’t reported as a side effect in people taking the medication in clinical studies.
Are there any long-term side effects of Revlimid?
It’s possible that Revlimid can cause long-term side effects. For example, this medication may cause:
What is a boxed warning on Revlimid?
Boxed warning. Revlimid has a boxed warning about the risk of harm or death to a fetus. (Boxed warnings are serious warnings from the FDA.) This medication can cause problems with fetal development, which are commonly known as birth defects.
How to help with constipation with revlimid?
They may be able to suggest ways to relieve your constipation. These may include taking a fiber supplement or another medication to treat your symptoms.
Can Revlimid cause low blood count?
Severely low levels of blood cells. Revlimid may cause you to experience severely low blood counts. These include neutropenia (low levels of white blood cells) and thrombocytopenia (low levels of platelets). Low levels of blood cells can cause problems with blood clotting or may increase your risk of infection. Low blood counts are a common but serious side effect that may occur during Revlimid treatment.
