Precautions
Does glycopyrrolate cross blood-brain barrier?
Atropine and scopolamine are tertiary amines and can easily cross the placenta and the blood–brain barrier into the brain; glycopyrrolate is a quaternary amine and does not cross the blood–brain barrier.
What drugs should not be taken with glycopyrrolate?
You should not take potassium chloride tablets or other potassium supplements (in tablet or capsule forms) while using this medicine. Using these medicines together may cause delayed movement of the potassium supplement through the esophagus and stomach. This medicine may cause constipation or diarrhea.
What is the half life of Robinul?
Mechanism of Action Glycopyrrolate exhibits onset of action within 1 minute when given intravenously and an elimination half-life of approximately 50 minutes. Glycopyrrolate undergoes urinary excretion and elimination.
How long does oral glycopyrrolate stay in your system?
How Long Does Glycopyrrolate Stay In Your System? Glycopyrrolate takes around 2 to 4 hours to be excreted from the body through urination.
What does glycopyrrolate do to the heart?
The higher doses of atropine (720 micrograms) and glycopyrrolate (300 micrograms) administered as a continuous infusion in 15 min produced an equal vagal cardiac blockade characterised by significant tachycardia and a decrease in overall and beat-to-beat heart rate variability.
What does glycopyrrolate do to your body?
Glycopyrrolate (Cuvposa) is used to reduce saliva and drooling in children between 3 and16 years of age that have certain medical conditions that cause drooling. Glycopyrrolate is in a class of medications called anticholinergics.
What happens if you take too much glycopyrrolate?
What happens if I overdose on Glycopyrrolate (Robinul)? Overdose symptoms may include severe muscle weakness, loss of movement, dilated pupils, jerky muscle movements, or seizure (convulsions).
What are the side effects of Robinul?
Drowsiness, dizziness, weakness, blurred vision, dry eyes, dry mouth, constipation, or abdominal bloating may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Is Robinul safe?
Use Robinul with caution in the elderly and in all patients with autonomic neuropathy, hepatic disease, ulcerative colitis, prostic hypertrophy, or hiatal hernia, since anticholinergic drugs may aggravate these conditions.
Do I have to take glycopyrrolate every day?
People typically take glycopyrrolate as tablets or a liquid, by mouth, either two or three times per day on an empty stomach – usually one hour before or two hours after a meal. Appropriate dosage is based on your specific medical condition, documented response to treatment and body weight.
Does Robinul increase blood pressure?
Drug interactions of Robinul include anti-cholinergic drugs such as phenothiazines, Parkinson's drugs, or tricyclic antidepressants because the combination can significantly increase anticholinergic side effects like pupil dilation, high blood pressure (hypertension), flushing, fever, and increased heart rate.
How often can you take glycopyrrolate?
Adults—1.7 milligrams (mg) 2 to 3 times a day. Your doctor will adjust the dose as needed. However, the dose is usually not more than 6.8 mg per day. Children—Use and dose must be determined by your doctor.
Can glycopyrrolate cause high blood pressure?
Drug interactions of Robinul include anti-cholinergic drugs such as phenothiazines, Parkinson's drugs, or tricyclic antidepressants because the combination can significantly increase anticholinergic side effects like pupil dilation, high blood pressure (hypertension), flushing, fever, and increased heart rate.
Can you drink while taking glycopyrrolate?
Alcohol may increase drowsiness and dizziness while you are taking glycopyrrolate. You should be warned not to exceed recommended dosages and to avoid activities requiring mental alertness. If your doctor prescribes these medications together, you may need a dose adjustment to safely take this combination.
Can you take advil with glycopyrrolate?
No interactions were found between ibuprofen and Robinul. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Can you take mucinex with glycopyrrolate?
Interactions between your drugs Glycopyrrolate may increase the effects of phenylephrine on your blood pressure and heart rate. Before receiving these medications, you should let your doctor know if you have high blood pressure or heart disease.
Robinul Description
Glycopyrrolate is used with other drugs to treat a certain type of stomach/intestinal ulcer (peptic ulcer).
May Treat: Adjunct therapy for peptic ulcer disease · Bronchospasm with COPD · General anesthesia adjunct · Irritable bowel syndrome · Sialorrhea and more
Drug Class: Asthma/COPD - Anticholinergic Agents, Inhaled Long Acting · GI Antispasmodic - Quaternary Ammonium Compounds · Therapy for Drooling- primary or secondary sialorrhea-Anticholinergic
Availability: Prescription Required
Pregnancy: Consult a doctor before using
Lactation: Consult a doctor before using
May Treat: Adjunct therapy for peptic ulcer disease · Bronchospasm with COPD · General anesthesia adjunct · Irritable bowel syndrome · Sialorrhea and more
Drug Class: Asthma/COPD - Anticholinergic Agents, Inhaled Long Acting · GI Antispasmodic - Quaternary Ammonium Compounds · Therapy for Drooling- primary or secondary sialorrhea-Anticholinergic
Availability: Prescription Required
Pregnancy: Consult a doctor before using
Lactation: Consult a doctor before using
Alcohol: Limit intake while taking this medication
Driving: May cause drowsiness or dizziness. Use caution
Manufacturer: BAXTER HEALTHCA · CASPER PHARMA L · SHIONOGI PHARMA
- Use candy or gum for relief
- For capsule, with inhalation device products : Use capsules in inhaler. Do not swallow capsules. May blur vision. Use caution when driving. Call MD immediately for eye pain or halos. Tell Dr. if using rescue inhaler more & more often. Store in a cool and dry place. Tell doctor your complete medical history. Take doses regularly, even when feeling well.
- For solution, oral products : If available, read the patient package insert. Measure dose using a dosing spoon/cup/syringe. Take on empty stomach 1hr prior or 2 hr after meals.
- Use candy or gum for relief
- For capsule, with inhalation device products : Use capsules in inhaler. Do not swallow capsules. May blur vision. Use caution when driving. Call MD immediately for eye pain or halos. Tell Dr. if using rescue inhaler more & more often. Store in a cool and dry place. Tell doctor your complete medical history. Take doses regularly, even when feeling well.
- For solution, oral products : If available, read the patient package insert. Measure dose using a dosing spoon/cup/syringe. Take on empty stomach 1hr prior or 2 hr after meals.
- For tablet products : May make you drowsy or dizzy. Drive with caution. May cause blurred vision. Avoid alcohol/other drugs that make you sleepy. Seniors more prone to dry mouth & constipation. Drink plenty of water and avoid getting overheated. May cause dry mouth. Review all drugs you are taking with your doctor. Call doctor if you are not getting better.
- For tablet, disintegrating products : Peel open with dry hands & place tablet on tongue.
Contraindications
Warnings
Precautions
Adverse Reactions
Overdosage
Dosage & Administration
How Is Robinul Supplied
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