Precautions
The best time of day to take pantoprazole is in the morning before or during breakfast, but it can be taken any time of day as long as it is taken immediately before the meal. Patients may take pantoprazole in the form of a tablet or an oral suspension. Pantoprazole tablets should be swallowed whole and should not be crushed, divided, or chewed.
What is the best time of day to take pantoprazole?
Taking Hypothyroidism Drugs
- Consistency. Missing even a day or two of your thyroid drugs can stir up symptoms. ...
- Pregnancy Concerns. See your healthcare provider right away if you become pregnant while on thyroid drugs. ...
- Switching Brands. ...
- Timing. ...
- Food Interactions. ...
- Drug Interactions. ...
- Supplement Interactions. ...
- Medical Conditions. ...
- Potential Allergies. ...
- Oral vs. ...
When to take pantoprazole correctly?
Pantoprazole is normally taken short-term (up to 8 weeks) unless it is being used for hypersecretory conditions such as Zollinger-Ellison syndrome in adults. Talk to your doctor about how long you need to stay on pantoprazole.
How long should I take pantoprazole?
- Zantac 75 (ranitidine) doesn't work as quickly as some other acid reducers. ...
- Zantac 75 (ranitidine) does not last as long as some other acid reducers. ...
- May not be as effective in healing the esophagus when it is inflammed or torn, known as erosive esophagitis. ...
- Can lower your vitamin B12 levels if you use Zantac 75 (ranitidine) for a long time. ...
Which medicine is better, ranitidine or pantoprazole?
What is the best way to take pantoprazole?
It's best to take pantoprazole an hour before a meal. Swallow tablets whole with a drink of water.
What do you need to know before administering pantoprazole?
Patient/Client-Related InstructionAdvise patient to avoid alcohol and foods that may cause an increase in GI irritation.Instruct patient to report bothersome or prolonged side effects, including headache or GI effects (diarrhea, flatulence, belching, abdominal pain).
How do you dilute pantoprazole?
Combine the contents of the two vials and further dilute with 80 mL of 5% Dextrose Injection, USP, 0.9% Sodium Chloride Injection, USP, or Lactated Ringer's Injection, USP, to a total volume of 100 mL with a final concentration of approximately 0.8 mg/mL. 3. Inspect the diluted PROTONIX I.V.
Is pantoprazole given IM?
Pantoprazole injection is for intravenous use only; do not administer intramuscularly or by subcutaneous injection. Administer pantoprazole IV either through a dedicated IV line or a Y-site.
What should be monitored when taking pantoprazole?
Patients who are prescribed pantoprazole require monitoring for signs and symptoms of gastroesophageal reflux disease and peptic ulcer disease. If symptoms of these conditions arise, an increase in dosage or medication change should merit clinician consideration.
Should pantoprazole be taken on an empty stomach?
You can take PROTONIX tablets with food or on an empty stomach. Swallow PROTONIX tablets whole. If you have trouble swallowing a PROTONIX 40 mg tablet, you can take two 20 mg tablets instead.
How long do you push IV pantoprazole?
PROTONIX I.V. for Injection should be administered intravenously over a period of approximately 15 minutes at a rate of approximately 7 mL/min.
How do you give pantoprazole 40 mg?
DosingFor erosive esophagitis: Adults—40 milligrams (mg) once a day for up to 8 weeks. Your doctor may want you to take pantoprazole for more than 8 weeks for certain conditions. ... For Zollinger-Ellison syndrome: Adults—At first, 40 milligrams (mg) 2 times a day. Your doctor may increase your dose as needed.
How do you give a pan 40 injection?
PD Pan 40mg Injection prevents acidity and stomach ulcers associated with the intake of painkillers. PD Pan 40mg Injection is taken 1 hour before a meal. On the other hand, painkillers are usually taken with, or after a meal to avoid stomach upset.
Why IV pantoprazole is given?
Pantoprazole injection is used to treat certain conditions in which there is too much acid in the stomach. It is used for short-term treatment (7 to 10 days) of gastroesophageal reflux disease (GERD) with a history of erosive esophagitis.
How do you give an IV injection?
How it worksInject a needle into the person's vein.Push a small plastic catheter over the needle and into the vein.Remove the needle, leaving the catheter in place.Place an access cap over the catheter, which allows them to administer medications without having to re-inject a needle.
Which injection is given in stomach?
A subcutaneous (say "sub-kyoo-TAY-nee-us") shot is an injection of medicine under the skin, but not in a muscle. Some medicines, such as insulin or the blood-thinner enoxaparin (Lovenox), are injected only under the skin. This type of shot is usually given in the belly or the thigh.
What should you assess before giving Protonix?
Assess the patient for signs and symptoms of stomach pain, heartburn or reflux, stomach upset, nausea or vomiting, and GI bleeding. To confirm the indication for administering pantoprazole. Check the patient's allergy status. Previous allergic reaction to pantoprazole will render the patient unable to take them.
What are the contraindications of pantoprazole?
Who should not take PANTOPRAZOLE SODIUM?diarrhea from an infection with Clostridium difficile bacteria.inadequate vitamin B12.low amount of magnesium in the blood.a type of kidney inflammation called interstitial nephritis.subacute cutaneous lupus erythematosus.systemic lupus erythematosus, an autoimmune disease.More items...
What are the side effects of taking pantoprazole?
Side EffectsBlurred vision.flushed, dry skin.fruit-like breath odor.increased hunger.increased thirst.increased urination.stomach pain.trouble breathing.More items...
What should you not take with pantoprazole?
Do not use pantoprazole together with medicines containing rilpivirine (eg, Complera®, Edurant®, Odefsey®).
When should you take pantoprazole?
Take pantoprazole tablets immediately before a meal, preferably in the morning. Pantoprazole tablets may be taken with food or on an empty stomach....
Can pantoprazole cause anxiety?
Pantoprazole may cause side effects, but it does not seem to cause anxiety. Some people in clinical trials reported headaches while taking pantopra...
How long does pantoprazole take to work?
Pantoprazole starts to work within 2 and a half (2.5) hours – this is the time it takes for it to block the secretion of acid in the stomach - and...
Pantoprazole vs. omeprazole: What's the difference between them?
Pantoprazole and omeprazole are both medicines from the class of medications called proton pump inhibitors (PPIs). The approved uses for pantoprazo...
Can you take pantoprazole 40 mg twice a day?
The usual dosage for pantoprazole 40mg is 40mg once a day if you are buying it without a prescription or a physician's evaluation of your symptoms....
How long can I take pantoprazole?
You should only take pantoprazole for up to 8 weeks if you are buying it without a prescription or a physician evaluation of your symptoms. This is...
Does pantoprazole cause bloating?
Bloating has been reported as a side effect of regular pantoprazole use. One study reported bloating in 43% of patients taking a similar proton pum...
1. How it works
Pantoprazole is an acid-suppressing agent that may be used to treat conditions associated with excessive stomach acid production, such as gastroesophageal reflux (GERD), stomach ulcers, erosive esophagitis, and Zollinger-Ellison syndrome.
2. Upsides
Oral pantoprazole may be used for the short-term treatment of erosive or nonerosive gastroesophageal reflux disease (GERD) in adults and children over the age of 5 years. May also be used for the maintenance healing of erosive esophagitis to reduce relapse rates of daytime and nighttime heartburn symptoms in adults.
3. Downsides
If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include:
4. Bottom Line
Pantoprazole is a proton pump inhibitor that decreases acid secretion in the stomach and may be given to relieve the symptoms of heartburn or to allow inflamed tissue in the gastrointestinal tract to heal. Pantoprazole tablets are delayed-release and should not be split, crushed, or chewed; pantoprazole oral granules are available.
6. Response and effectiveness
The onset of action for acid secretion is 2.5 hours for oral pantoprazole and 15 to 30 minutes for IV pantoprazole (maximum effect 2 hours). The time to peak is 0.34 hours for the IV and 2.54 hours for the oral.
7. Interactions
Medicines that interact with pantoprazole may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with pantoprazole. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does.
Further information
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use pantoprazole only for the indication prescribed.
Expert Q&A
Include your email address to get a message when this question is answered.
Tips
There are many other medicines that fulfill the same role as pantoprazole, such as omeprazole (Prilosec), lansoprazole (Prevacid), rabeprazole (Aciphex), esomeprazole (Nexium), dexlansoprazole (Dexilant).
Warnings
Although pantoprazole is safe to use if you're breastfeeding, you shouldn't take it if you're pregnant. Talk with your doctor about taking omeprazole instead.
About This Article
This article was medically reviewed by Erik Kramer, DO, MPH and by wikiHow staff writer, Jessica Gibson. Dr. Erik Kramer is a Primary Care Physician at the University of Colorado, specializing in internal medicine, diabetes, and weight management.
What is pantoprazole?
Pantoprazole is a proton pump inhibitor that decreases the amount of acid produced in the stomach.
Before taking this medicine
Heartburn can mimic early symptoms of a heart attack. Get emergency medical help if you have chest pain that spreads to your jaw or shoulder and you feel anxious or light-headed.
How should I use pantoprazole?
Take pantoprazole exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Dosing information
Treatment of Erosive Esophagitis: 40 mg orally once a day for up to 8 weeks; however an additional 8 weeks may be considered for patients who have not healed after the initial treatment. Safety and efficacy beyond 16 weeks of therapy have not been established. Maintenance of Healing of Erosive Esophagitis: 40 mg orally once a day.
What happens if I miss a dose?
Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while using pantoprazole?
This medicine can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.
2 DOSAGE AND ADMINISTRATION
The recommended adult dosage of PROTONIX I.V. is 40 mg given once daily by intravenous infusion for 7 to 10 days.
3 DOSAGE FORMS AND STRENGTHS
For Injection: 40 mg of pantoprazole white to off-white freeze-dried powder in a single-dose vial for reconstitution.
4 CONTRAINDICATIONS
PROTONIX I.V. is contraindicated in patients with known hypersensitivity reactions including anaphylaxis to the formulation or any substituted benzimidazole. Hypersensitivity reactions may include...
5 WARNINGS AND PRECAUTIONS
In adults, symptomatic response to therapy with PROTONIX I.V. does not preclude the presence of gastric...
6 ADVERSE REACTIONS
The following serious adverse reactions are described below and elsewhere in labeling:
7 DRUG INTERACTIONS
Table 2 includes drugs with clinically important drug interactions and interaction with diagnostics when administered concomitantly with PROTONIX I.V. and instructions for preventing or managing them....
10 OVERDOSAGE
Experience in patients taking very high doses of pantoprazole (greater than 240 mg) is limited. Adverse reactions seen in spontaneous reports of overdose generally reflect the known safety profile of...
How it works
Pantoprazole belongs to a class of drugs called proton pump inhibitors. It works to shut off the acid-pumping cells in your stomach. It reduces the amount of stomach acid and helps to reduce painful symptoms related to conditions such as GERD.
More common side effects
The more common side effects that can occur with pantoprazole include:
Serious side effects
Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:
HIV drugs
Taking certain HIV drugs with pantoprazole is not recommended. Pantoprazole may significantly decrease the amount of these drugs in your body. This can reduce their ability to control HIV infection. These drugs are:
Anticoagulant
Some people taking warfarin with pantoprazole can experience increases in INR and prothrombin time (PT). This can lead to an increased risk of severe bleeding. If you take these drugs together, your doctor should monitor you for increases in INR and PT.
Drugs affected by stomach pH
Pantoprazole affects stomach acid levels. As a result, it can reduce your body’s absorption of certain drugs that are sensitive to the effects of decreased stomach acid. This effect can make these drugs less effective.
Cancer drug
Taking methotrexate with pantoprazole may increase the amount of methotrexate in your body. If you’re taking high doses of methotrexate, your doctor may have you stop taking pantoprazole during your methotrexate therapy.
1 INDICATIONS AND USAGE
PROTONIX For Delayed-Release Oral Suspension and PROTONIX Delayed-Release Tablets are indicated for:
2 DOSAGE AND ADMINISTRATION
PROTONIX is supplied as delayed-release granules in packets for preparation of oral suspensions or as...
4 CONTRAINDICATIONS
PROTONIX is contraindicated in patients with known hypersensitivity to any component of the formulation or any substituted benzimidazole. Hypersensitivity reactions may include anaphylaxis, anaphylactic shock,...
5 WARNINGS AND PRECAUTIONS
In adults, symptomatic response to therapy with PROTONIX does not preclude the presence of gastric...
7 DRUG INTERACTIONS
Table 4 includes drugs with clinically important drug interactions and interaction with diagnostics when administered concomitantly with PROTONIX and instructions for preventing or managing them.
10 OVERDOSAGE
Experience in patients taking very high doses of PROTONIX (greater than 240 mg) is limited. Spontaneous post-marketing reports of overdose are generally within the known safety profile of PROTONIX.
11 DESCRIPTION
The active ingredient in PROTONIX (pantoprazole sodium) For Delayed-Release Oral Suspension and PROTONIX (pantoprazole sodium) Delayed-Release Tablets, a PPI, is a substituted benzimidazole, sodium 5- (...
How It Works
Pantoprazole is used to treat certain stomach and esophagus problems (such as acid reflux).
May Treat: Gastroesophageal reflux disease · Erosive esophagitis · Zollinger-Ellison syndrome · Acute gastric ulcer with hemorrhage · Gastric hypersecretion with systemic mastocytosis and more
Brand Names: Protonix
Drug Class: Gastric Acid Secretion Reducer - Proton Pump Inhibitors (PPIs)
Availability: Prescription Required
Pregnancy: Consult a doctor before using
Lactation: Consult a doctor before using
- Call doctor if you are not getting better
- Call doctor if you are not getting better
- Call MD now for heartburn with sweating & dizziness
- Call doctor if you get severe diarrhea
- For granules delayed release for susp packet products : Wash down as directed. DO NOT chew granules.
- For tablet, delayed release products : Before use, important to read the Medication Guide. Call MD or RPh re. timing of taking with other meds. Swallow whole. Do not break/chew/crush/dissolve. Success is dependent on completing therapy course. May increase risk of bone fractures.
- For vial products : For intravenous injection dilute prior to use. Prepare carefully as you have been shown. Take at the same time(s) daily as directed. Recommended for short term use only. Tell doctor your complete medical history.
Upsides
Downsides
Bottom Line
Tips
- The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of...
Response and Effectiveness
Interactions
Further Information