Precautions
you should know that nitroglycerin patches may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position, or at any time, especially if you have been drinking alcoholic beverages. To avoid this problem, get up slowly, resting your feet on the floor for a few minutes before standing up.
What are side effects of nitroglycerin patch?
Severe side effects that doctors associate with a nitroglycerin overdose include:
- a sudden drop in blood pressure
- an increased heart rate
- increased blood flow and pressure in the brain
- throbbing headaches
- confusion
- dizziness
- disturbances in vision
What are the side effects of nitroglycerin?
Taking nitroglycerin when not needed can lead to severe headaches for one. It also could lead to an unsafe drop in blood pressure and can cause tachycardia which is a rapid heart rate, palpitations and fainting. He should probably be tapered down off the medication if he has been on more than a few weeks.
What happens if you take nitroglycerin and don't need it?
Nitroglycerin relaxes smooth muscle within the walls of blood vessels (particularly veins) which dilates (widens) them. This helps to relieve chest pain that is caused by a narrowing of the blood vessels, and also reduces how hard the heart has to work to pump blood around the body, reducing blood pressure.
What are nitroglycerin patches used for blood pressure?
Where to put nitroglycerin patch?
What is the process of breaking down nitroglycerin?
How much nitroglycerin is in a tablet?
Why do doctors use nitroglycerin?
Why do people take nitroglycerin?
How long before an activity can you take nitroglycerin?
What is the PDE-5 inhibitor?
See 4 more
About this website
Uses of Nitroglycerin Transdermal Patch
1. It is used to prevent chest pain or pressure. 2. It may be given to you for other reasons. Talk with the doctor.
What Do I Need to Tell My Doctor Before I Take Nitroglycerin Transdermal Patch?
1. If you have an allergy to nitroglycerin or any other part of nitroglycerin transdermal patch. 2. If you are allergic to any drugs like this one,...
What Are Some Things I Need to Know Or Do While I Take Nitroglycerin Transdermal Patch?
1. Tell all of your health care providers that you take nitroglycerin transdermal patch. This includes your doctors, nurses, pharmacists, and denti...
How Is This Medicine (Nitroglycerin Transdermal Patch) Best Taken?
Use nitroglycerin transdermal patch as ordered by your doctor. Read all information given to you. Follow all instructions closely. 1. To gain the m...
What Are Some Side Effects That I Need to Call My Doctor About Right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor o...
What Are Some Other Side Effects of Nitroglycerin Transdermal Patch?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help i...
How Do I Store and/or Throw Out Nitroglycerin Transdermal Patch?
1. Store at room temperature. 2. Store in a dry place. Do not store in a bathroom. 3. Throw away all patches in a sealed container away from childr...
Where to put nitroglycerin patch?
A person places the patch on their skin anywhere except the areas below the knee and elbow. Most people place the patch on their chest. The area should be clean, dry, and hairless to allow the nitroglycerin to absorb across the skin.
What is the process of breaking down nitroglycerin?
The body breaks nitroglycerin down into nitric oxide. Nitric oxide causes the smooth muscle within the blood vessels to relax. This allows the arteries and veins to open up, allowing more blood to flow through. Healthcare professionals call this action vasodilation.
How much nitroglycerin is in a tablet?
Generic nitroglycerin comes in the form of a sublingual tablet. The strengths of these tablets are 0.3 mg, 0.4 mg, and 0.6 mg.
Why do doctors use nitroglycerin?
Uses. Doctors usually use nitroglycerin to treat the pain that angina causes. Narrowing of the arteries that supply the heart with blood is what causes unstable angina. Doctors call this condition coronary artery disease (CAD). CAD is the most common type of heart disease. More than 370,000 people.
Why do people take nitroglycerin?
People often use the drug nitroglycerin to relieve chest pain that angina causes . Most often, the reason for the decrease in blood flow is plaque formation and narrowing of the arteries supplying blood to the heart. Nitroglycerin helps to open up the blood vessels and allow blood to flow. People also use nitroglycerin to treat chronic anal fissures.
How long before an activity can you take nitroglycerin?
People can also take fast-acting nitroglycerin formulations 5 to 10 minutes before doing an activity that may cause an angina attack.
What is the PDE-5 inhibitor?
PDE-5 inhibitors are drugs that doctors give to treat erectile dysfunction in males. Viagra, Cialis, and Levitra are PDE-5 inhibitors. As with nitroglycerin, these drugs also cause increased blood flow and can lower blood pressure.
How should this medicine be used?
Transdermal nitroglycerin comes as a patch to apply to the skin. It is usually applied once a day, worn for 12 to 14 hours, and then removed. Apply nitroglycerin patches at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use nitroglycerin patches exactly as directed. Do not apply more or fewer patches or apply the patches more often than prescribed by your doctor.
What is nitroglycerin patch?
Nitroglycerin transdermal patches are used to prevent episodes of angina (chest pain) in people who have coronary artery disease (narrowing of the blood vessels that supply blood to the heart). Nitroglycerin transdermal patches can only be used to prevent attacks of angina; they cannot be used to treat an attack of angina once it has begun.
How to avoid getting headaches with nitroglycerin?
To avoid this problem, get up slowly, resting your feet on the floor for a few minutes before standing up. Take extra precautions to avoid falling during your treatment with nitroglycerin patches. you should know that you may experience headaches every day during your treatment with nitroglycerin patches.
What to do if you are allergic to nitroglycerin?
tell your doctor and pharmacist if you are allergic to nitroglycerin patches, tablets, spray, or ointment; any other medications; adhesives; or any of the ingredients in nitroglycerin skin patches. Ask your pharmacist for a list of the ingredients.
What to keep on a prescription list?
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Can you stop using nitroglycerin patches?
Nitroglycerin patches help prevent attacks of angina but do not cure coronary artery disease. Continue to use nitroglycerin patches even if you feel well. Do not stop using nitroglycerin patches without talking to your doctor.
What is the phone number to call for poison control?
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
What are some things I need to know or do while I take Nitroglycerin Transdermal Patch?
Tell all of your health care providers that you take nitroglycerin transdermal patch. This includes your doctors, nurses, pharmacists, and dentists.
How is this medicine (Nitroglycerin Transdermal Patch) best taken?
Use nitroglycerin transdermal patch as ordered by your doctor. Read all information given to you. Follow all instructions closely.
What do I need to tell my doctor BEFORE I take Nitroglycerin Transdermal Patch?
Tell your doctor about the allergy and what signs you had.
How to avoid passing out from nitroglycerin?
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Be careful going up and down stairs.
How many missed patches can you put on at once?
If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not put on more than 1 patch at a time .
Can nitroglycerin cause headaches?
You may have headaches when you start taking nitroglycerin transdermal patch. Most of the time it gets better with time. Do not change how you use nitroglycerin transdermal patch to avoid these headaches. Talk with your doctor for ways to lessen this side effect. These are not all of the side effects that may occur.
Can you use nitroglycerin transdermal patch?
Keep using nitroglycerin transdermal patch as you have been told by your doctor or other health care provider, even if you feel well.
Where to put nitroglycerin patch?from medicalnewstoday.com
A person places the patch on their skin anywhere except the areas below the knee and elbow. Most people place the patch on their chest. The area should be clean, dry, and hairless to allow the nitroglycerin to absorb across the skin.
What is the process of breaking down nitroglycerin?from medicalnewstoday.com
The body breaks nitroglycerin down into nitric oxide. Nitric oxide causes the smooth muscle within the blood vessels to relax. This allows the arteries and veins to open up, allowing more blood to flow through. Healthcare professionals call this action vasodilation.
What should I know about storage and disposal of this medication?from medlineplus.gov
Keep this medication in the container it came in, tightly closed after each use, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).
What is nitroglycerin IV?from ncbi.nlm.nih.gov
There are intravenous (IV) routes of administration for nitroglycerin used most commonly in emergency rooms and intensive care units (ICU). It is administered as a 5% dextrose in drip and is indicated when sublingual nitroglycerin has failed to provide symptomatic relief or if rapid and continued relief of symptoms is necessary. Intravenous nitroglycerin is frequently used to treat acute coronary syndromes, hypertensive emergency, and acute congestive heart failure (CHF) exacerbations. [9][10] When administered, its effect requires tight vitals monitoring, as discussed below. It should be kept in mind that continuous intravenous infusion of nitrates can lead to the development of tolerance. It is important to switch patients to oral form with intermittent dose and long nitrate-free intervals to avoid tolerance. Sometimes in a catheterization laboratory, nitroglycerin can be given intracoronary as a treatment for no-reflow.[11] Nitroglycerin provides rapid coronary vasodilation when given intracoronary.
What are the contraindications for nitroglycerin?from ncbi.nlm.nih.gov
The contraindications of nitroglycerine therapy include: 1 Allergic reactions to nitroglycerin are extremely rare, but reports do exist. Nitroglycerin is contraindicated in patients that have reported allergic symptoms to the medication. 2 Known history of increased intracranial pressure, severe anemia, right-sided myocardial infarction, or hypersensitivity to nitroglycerin are contraindications to nitroglycerin therapy. 3 Concurrent use of nitroglycerin with PDE-5 inhibitors (e.g., sildenafil citrate, vardenafil hydroxide, tadalafil) is absolutely contraindicated. PDE-5 inhibitors have proven to accentuate the hypotensive effects of nitrates and precipitate syncopal episodes.
How many micrograms of nitroglycerin are in a packet?from medicalnewstoday.com
A sublingual packet of nitroglycerin contains 400 micrograms of nitroglycerin powder. A person places the contents of the packet under their tongue when angina pains begin.
Why do people take nitroglycerin?from medicalnewstoday.com
People often use the drug nitroglycerin to relieve chest pain that angina causes . Most often, the reason for the decrease in blood flow is plaque formation and narrowing of the arteries supplying blood to the heart. Nitroglycerin helps to open up the blood vessels and allow blood to flow. People also use nitroglycerin to treat chronic anal fissures.
How to use a patch system?
For patients using the patch system: Wash your hands with soap and water before and after applying a patch. Do not touch your eyes until after you have washed your hands. Do not try to trim or cut the adhesive patch to adjust the dosage. Check with your doctor if you think the medicine is not working as it should.
How long does nitrate help with angina?
The ointment and patch forms release medicine gradually to provide an effect for 7 to 10 hours. Check with your doctor if you also need a fast-acting medicine to relieve the pain of an angina attack.
How to apply ointment to skin?
Do not rub or massage the ointment into the skin. Spread it in a thin, even layer, and cover an area of skin that is the same size each time it is applied. Apply the ointment to skin with little or no hair that is free of scars, cuts, or irritation. Apply each dose of ointment to a different area of skin to prevent irritation.
What to do if you miss a dose of a syringe?
Missed Dose. If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. If you forget to wear or change a patch, put one on as soon as you can.
When to apply a new patch?
Apply a new patch if the first one becomes loose or falls off.
Can you put plastic wrap over a medicine?
If your doctor has ordered an airtight covering or dressing (such as plastic kitchen wrap) be placed over this medicine, make sure you know how to apply it. Airtight dressings will increase the amount of medicine absorbed through the skin and may cause more side effects. Use them only as directed and check with your doctor if you have any questions about this.
Can you use nitroglycerin before applying a new ointment?
Before applying a new dose of ointment, remove any ointment remaining on the skin from a previous dose. This will allow the fresh ointment to release the nitroglycerin properly. This medicine comes with papers to help measure the dose.
How to store nitroglycerin?
Store nitroglycerin at room temperature. Keep it between 59°F and 86°F (15°C and 30°C).
What is sublingual nitroglycerin?
A sublingual tablet is a tablet that you dissolve under your tongue or inside your cheek. Nitroglycerin also comes as a spray, aerosol solution, transdermal patch, and ointment. In addition, it comes in an injectable form that’s only given by a healthcare professional.
How to take sublingual tablet?
To take the sublingual tablet, you place it under your tongue or inside your cheek and let it dissolve.
Can Nitroglycerin cause dizziness?
Nitroglycerin can cause dizziness during the first few hours after you take it. You shouldn’t drive or use machinery until you know how this medication affects you. This drug can also cause other side effects.
Can nitroglycerin cause allergic reactions?
Allergic reactions to nitroglycerin are extremely rare, but they do occur. Symptoms can include:
Can nitroglycerin interact with other medications?
Nitroglycerin sublingual tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.
Where to dissolve a syringe?
Dissolve your dose under your tongue or in your cheek at the first sign of chest pain.
What is nitroglycerin used for?
Earn continuing education credits (CME/CE) on this topic. Indications. Nitroglycerin is a vasodilatory drug used primarily to provide relief from anginal chest pain. Nitroglycerin has been FDA approved since 2000 and was first sold by Pfizer under the brand name Nitrostat. It is currently FDA approved for the acute relief ...
How long does it take for nitroglycerin to absorb?
Absorption takes about 5 to 10 minutes for full effect.
What are the contraindications for nitroglycerin?
The contraindications of nitroglycerine therapy include: 1 Allergic reactions to nitroglycerin are extremely rare, but reports do exist. Nitroglycerin is contraindicated in patients that have reported allergic symptoms to the medication. 2 Known history of increased intracranial pressure, severe anemia, right-sided myocardial infarction, or hypersensitivity to nitroglycerin are contraindications to nitroglycerin therapy. 3 Concurrent use of nitroglycerin with PDE-5 inhibitors (e.g., sildenafil citrate, vardenafil hydroxide, tadalafil) is absolutely contraindicated. PDE-5 inhibitors have proven to accentuate the hypotensive effects of nitrates and precipitate syncopal episodes.
How long does nitroglycerin stay in the body?
Nitroglycerin is primarily eliminated via metabolism in the liver and has a mean half-life of approximately 2 to 3 minutes. There are intravenous (IV) routes of administration for nitroglycerin used most commonly in emergency rooms and intensive care units (ICU).
Does nitroglycerin cause venodilation?
Although nitroglycer in has a vasodilatory effect in both arteries and veins, the profound desired effects caused by nitroglycerin are primarily due to venodilation.[2] Venodilation causes pooling of blood within the venous system, reducing preload to the heart, which causes a decrease in cardiac work, reducing anginal symptoms secondary to demand ischemia. Arterial vasodilation will still occur and contribute to the relief of anginal symptoms. [3][4] Vasodilation of the coronary arteries will cause increased blood flow to the heart, increasing perfusion, but this effect remains minimal compared to the effects of venodilation.
Is Nitrous Oxide a vasodilatory drug?
This activity outlines the indications, mechanism of action, methods of administration, important adverse effects, contraindications, monitoring, and toxicity of nitrous oxide, so providers can direct patient therapy successfully in instances where nitrous oxide provides a benefit to patient care. Nitroglycerin is a vasodilatory drug used primarily ...
Is nitroglycerin safe for nursing?
Interprofessional team members including clinicians, cardiology specialists, primary care providers, pharmacists, internists, and nursing staff who work with patients taking nitroglycerin should be fully aware of the indications and contraindications of the drug, as well as the potential adverse effects. Overall, nitroglycerin is relatively safe, and monitoring of the levels is not required. In the event of overdose, monitoring vital signs may be necessary to monitor the hemodynamic effects of nitroglycerin. Continuous monitoring of blood pressure, heart rate, respiratory rate, and oxygen saturation is recommended. Pharmacists can assist the team by monitoring for drug-drug interactions. Nitroglycerin is pregnancy category C, and its use requires caution in breastfeeding mothers. It is currently unknown whether nitroglycerin is excreted in breast milk. Interprofessional collaboration and information sharing will drive better outcomes with fewer adverse events with nitroglycerine therapy. [Level 5]
What are the side effects of Nitro-Dur (nitroglycerin patch)?
With any medication, there are risks and benefits. Even if the medication is working, you may experience some unwanted side effects.
How much does Nitro-Dur (nitroglycerin patch) cost?
Nitro-Dur (nitroglycerin patch) is available as a generic medication and may be significantly cheaper compared to the brand version. Unless there is a specific reason you need the brand, the generic medication will be a better value. For even more savings, use a GoodRx coupon and pay just a fraction of the retail price.
How does nitro ur work?
How Nitro-Dur (nitroglycerin patch) works. Nitro-Dur (nitroglycerin patch) is a type of nitrate. Nitrates are vasodilators, which means that they work to relax your blood vessels. This makes the heart pump more easily and allows for better blood flow to the heart muscles, which relieves heart-related chest pain.
How long does it take to take a syringe off?
Apply the patch (es) daily for 12 to 14 hours, then take it off for 10 to 12 hours.
How to apply Nitro-Dur?
Apply the sticky side of the patch to clean, dry, hairless skin. Avoid applying Nitro-Dur (nitroglycerin patch) below the knee, below the elbow, or on skin that has folds, scar tissue, injuries, or irritation. Apply the patch to a different area of the body every day to help prevent skin irritation.
Can you take nitroglycerin under the tongue?
Your provider might also prescribe an "under-the-tongue" nitroglycerin that works fast er. If you have to take this for active chest pain, make sure to sit down first to avoid side effects like low blood pressure and dizziness. Wash your hands before and after applying a new Nitro-Dur (nitroglycerin patch) patch.
Do Nitro Dur patches go away?
Used patches still contain medication. Make sure you throw it away in a place that is out of reach of children and pets. Do not stop using Nitro- Dur (nitroglycerin patch) unless your provider has told you to do so.
When to take Nitroglycerin?
Yet as Dr. Lown advises, nitroglycerin is most helpful when taken at the first onset of chest discomfort – rather than after it has been present for several minutes.
When was Nitroglycerin first used?
While many heart patients now know and love nitro as an effective vasodilator to treat severe chest pain symptoms or heart failure, nitroglycerin has also been used since the 1860s as an active ingredient in the manufacture of explosives, most notably dynamite, patented in 1867 by the famous scientist, Alfred Nobel.
How does positive drug action work?
When it is taken properly – positive drug action is hastened by sitting, leaning forward, inhaling deeply, and bearing down as if for a bowel movement – it can help patients with angina achieve the goal of a pain-free life with little or no limitations.
Does nitroglycerin help with angina?
It is common to see patients with angina return to full activity , largely because they have mastered the proper use of nitroglycerin. “No matter how often you use it, it will consistently continue to work. It can help in the following circumstances: Brisk walking. Cold, windy weather.
Who was the first person to use Nitroglycerin?
Ironically, many years later, Alfred Nobel – the scientist who had first used nitro in the dynamite his company patented – was prescribed nitroglycerin for his own chronic angina pain.
Is nitroglycerin a long acting medication?
Nitroglycerin (or nitroglycerine, glyceryl trinitrate, or GTN) comes in either short- or long-acting forms: spray, pills, skin ointment or transdermal patch, and as the AHA journal reminds us, it’s still one of the least expensive – and most immediately effective – of all my cardiac meds.
Is nitroglycerin a wonder drug?
During worry, tension or anger. “Nitroglycerin is truly a wonder drug. It dilates coronary arteries and decreases the workload of the heart, two factors responsible for the discomfort. “Yet many anginal patients use the drug only sparingly, if at all.
Where to put nitroglycerin patch?
A person places the patch on their skin anywhere except the areas below the knee and elbow. Most people place the patch on their chest. The area should be clean, dry, and hairless to allow the nitroglycerin to absorb across the skin.
What is the process of breaking down nitroglycerin?
The body breaks nitroglycerin down into nitric oxide. Nitric oxide causes the smooth muscle within the blood vessels to relax. This allows the arteries and veins to open up, allowing more blood to flow through. Healthcare professionals call this action vasodilation.
How much nitroglycerin is in a tablet?
Generic nitroglycerin comes in the form of a sublingual tablet. The strengths of these tablets are 0.3 mg, 0.4 mg, and 0.6 mg.
Why do doctors use nitroglycerin?
Uses. Doctors usually use nitroglycerin to treat the pain that angina causes. Narrowing of the arteries that supply the heart with blood is what causes unstable angina. Doctors call this condition coronary artery disease (CAD). CAD is the most common type of heart disease. More than 370,000 people.
Why do people take nitroglycerin?
People often use the drug nitroglycerin to relieve chest pain that angina causes . Most often, the reason for the decrease in blood flow is plaque formation and narrowing of the arteries supplying blood to the heart. Nitroglycerin helps to open up the blood vessels and allow blood to flow. People also use nitroglycerin to treat chronic anal fissures.
How long before an activity can you take nitroglycerin?
People can also take fast-acting nitroglycerin formulations 5 to 10 minutes before doing an activity that may cause an angina attack.
What is the PDE-5 inhibitor?
PDE-5 inhibitors are drugs that doctors give to treat erectile dysfunction in males. Viagra, Cialis, and Levitra are PDE-5 inhibitors. As with nitroglycerin, these drugs also cause increased blood flow and can lower blood pressure.
Medical uses
This medication is used to relieve chest pain (angina) in people that have a certain heart condition (coronary artery disease). It may also be used before physical activities (such as exercise, sexual activity) to help prevent chest pain.
Status: Discontinued
May Treat: Acute episode of anginal pain · Acute myocardial infarction · Anal fissure · Induction of intraoperative hypotension · Left ventricular dysfunction following MI and more
Alternate Brand Names: Nitrolingual
Drug Class: Anal Fissure Pain/Treatment Agents - Nitrates · Antianginal - Coronary Vasodilators (Nitrates)
Availability: Prescription Required
Status: Discontinued
May Treat: Acute episode of anginal pain · Acute myocardial infarction · Anal fissure · Induction of intraoperative hypotension · Left ventricular dysfunction following MI and more
Alternate Brand Names: Nitrolingual
Drug Class: Anal Fissure Pain/Treatment Agents - Nitrates · Antianginal - Coronary Vasodilators (Nitrates)
Availability: Prescription Required
Pregnancy: Consult a doctor before using
Lactation: Consult a doctor before using
Alcohol: Limit intake while taking this medication
Driving: May cause drowsiness or dizziness. Use caution
- Tell Dr. of all drugs as some drugs may interact
- Be careful not to stand up too quickly
- Limit its use
- Tell Dr. of all drugs as some drugs may interact
- Be careful not to stand up too quickly
- Limit its use
- Do not swallow whole or chew
- For aerosol, spray products : Get exact instructions for use from MD. If available, read the patient package insert. Do not shake the container. Spray onto or under the tongue. Do not inhale. Use at first sign of chest pain. After 1st dose, call 911 if pain is not improved. Caution.
- For capsule, extended release products : Swallow whole. Do not break/chew/crush/dissolve. Take doses regularly, even when feeling well. This medicine is usually not taken at night. Do not use to stop angina attack. Use regularly. May make you dizzy. Use caution when driving. May cause headache. May cause flushing.
- For ointment products : Know how to use before taking. For rectal use only. This medicine is usually not used at night. Alcohol can affect blood pressure. Check warnings on OTC medications. Close container tightly when not in use.
- For patch, transdermal 24 hours products : Apply to skin on abdomen upper arms, or shoulders. Dispose patch by folding sticky sides together. If having MRI, check if patch should be removed. MD may need to reduce the dose before you stop it.
- For powder in packet products : Read instructions carefully. Open with dry hands and place under the tongue. Store in a cool and dry place at room temperature.
- For tablet, sublingual products : Dissolve under tongue. Store tightly closed in the original container.
Usage
Prevention
Treatment
Risks
- Nitroglycerin transdermal patches are used to prevent episodes of angina (chest pain) in people who have coronary artery disease (narrowing of the blood vessels that supply blood to the heart). Nitroglycerin transdermal patches can only be used to prevent attacks of angina; they cannot be used to treat an attack of angina once it has begun. Nitrogl...
Preparation
- Transdermal nitroglycerin comes as a patch to apply to the skin. It is usually applied once a day, worn for 12 to 14 hours, and then removed. Apply nitroglycerin patches at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use nitroglycerin patches exactly as direc…