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how does group translocation work

by Rebeka Hackett Published 2 years ago Updated 1 year ago
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How does Group Translocation work? The phosphotransferase system picks up a phosphate group from PEP changing it into Pyruvate. The P group is then transferred along non-specific and specific enzymes and the membrane protein acts as a kinase adding the phosphate group to the glucose, forming Glucose6-P transferring glucose across the inner membrane.

Group translocation is a biological process where a molecule crossing the cell membrane not only gets transported but also gets transformed in itself. This is like a whole character “lift-up” for the molecule and its properties, nature, and functions get changed.Jun 16, 2022

Full Answer

What is group translocation?

What is Group Translocation? Group translocation is another form of active transport in which substances are subjected to covalent modification during the movement across the membrane. Phosphorylation is the main modification undergone by transported substances. During phosphorylation, a phosphate group is transferred from one molecule to another.

What is PEP group translocation?

PEP group translocation, also known as the phosphotransferase system or PTS, is a distinct method used by bacteria for sugar uptake where the source of energy is from phosphoenolpyruvate ( PEP ). It is known to be a multicomponent system that always involves enzymes of the plasma membrane and those in the cytoplasm .

Why is chromosomal translocation important?

The detection of chromosomal translocations can be important for the diagnosis of certain genetic diseases and disorders. Translocation. The Philadelphia chromosome is an abnormal chromosome that causes chronic myelogenous leukemia and a subset of other leukemias.

How do you transport sugar across a membrane?

group translocation A mechanism widely utilized for the transportation of sugars across bacterial membranes and perhaps those of some higher cells. A donor compound is used to activate sugar molecules through the provision of a high-energy phosphate group. The activated sugar can thus more readily traverse the membrane.

What is group translocation?

What is a donor compound?

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What is group translocation explain with example?

The process of coupled sugar uptake with sugar phosphorylation, involving substrate modification, is called 'group translocation'. The PTS serves as a chemoreception system, directing the activity of the bacterial flagellum so that bacteria swim up concentration gradients of nutrient sugars.

How does the group translocation different from other modes of transport in a bacterial cell?

Group translocation is a distinct type of active transport, using energy from an energy-rich organic compound that is not ATP. Group translocation also differs from both simple transport and ABC transporters in that the substance being transported is chemically modified in the process.

Does group translocation require energy?

No energy is required. Substrate is being modified. Channel is an integral membrane protein.

Why group translocation process is advantages over active transport?

The key difference between active transport and group translocation is that in active transport, substances are not chemically modified during the movement across the membrane while, in group, translocation substances are chemically modified.

What type of transport is group translocation?

active transportGroup translocation is a unique type of active transport, using energy from the energy-rich organic compounds other than ATP. However, it differs from other cotransporters and the ABC system as molecules transported by group translocation undergo chemical modifications.

What is group translocation active transport?

0:000:49Active Transport by Group Translocation Animation VideoYouTubeStart of suggested clipEnd of suggested clipGroup translocation is a process in which an organic molecule such as glucose is transported intoMoreGroup translocation is a process in which an organic molecule such as glucose is transported into the cell while being chemically modified. The PEP phospho transfer a system is an example of group

What is needed for translocation to occur?

​Translocation A translocation, as related to genetics, occurs when a chromosome breaks and the (typically two) fragmented pieces re-attach to different chromosomes. The detection of chromosomal translocations can be important for the diagnosis of certain genetic diseases and disorders.

How is ATP used in translocation?

Translocation could be supported by an ATP-generating system or, less well, by the protonmotive force generated by D-lactate oxidation; the latter might act by generating ATP from residual bound nucleotides. However, when protonmotive force inhibitors were used or when ATP was further depleted by E.

What factors are involved in translocation?

The most important factors influencing translocation are the physiological behaviour of radionuclides in the plant and the time at which the deposition occurs during the growth period.

Is translocation active or passive transport?

passiveIn contrast with transpiration, an entirely passive process, translocation as a passive process that is indirectly driven by active processes.

What are 4 methods of transport across the membrane?

Particles move across membranes by simple diffusion, facilitated diffusion, osmosis and active transport.

Is translocation an active process?

Translocation is the movement of organic compounds from where they are made at their source, to where they are required at their sink. It is an active process which can be used to transport phloem up or down the plant.

How is transportation and translocation different from each other?

The key difference between transportation and translocation is that transportation is the process that transports water from roots to other parts of the plant while translocation is the process that conducts sucrose from leaves to other parts of the plant.

What is the difference between transportation and translocation?

*Transpiration involves mainly the xylem cells which become active during absorption process by the roots while translocation involves both xylem and phloem cells to carry the synthesized food materials within the plant. Q. Q. Transpiration & Translocation occur through & tissues respectively.

What is the unique characteristic of group translocation?

Group translocation is a biological process where a molecule crossing the cell membrane not only gets transported but also gets transformed in itself. This is like a whole character “lift-up” for the molecule and its properties, nature, and functions get changed.

What are the differences between transformation and transduction in bacteria?

In transformation, a bacterium takes up a piece of DNA floating in its environment. In transduction, DNA is accidentally moved from one bacterium to another by a virus. In conjugation, DNA is transferred between bacteria through a tube between cells.

Group translocation - Definition and Examples - Biology Online Dictionary

Group translocation is a biological process where a molecule crossing the cell membrane not only gets transported but also gets transformed in itself. This is like a whole character “lift-up” for the molecule and its properties, nature, and functions get changed.. When asked whether the group translocation is active or passive, we can tell it’s active.

Group translocation | definition of group translocation by Medical ...

group translocation: a form of active transport across a biomembrane in which the transporting molecule is altered in the course of the transport.

PEP group translocation - Wikipedia

PEP group translocation, also known as the phosphotransferase system or PTS, is a distinct method used by bacteria for sugar uptake where the source of energy is from phosphoenolpyruvate (PEP).It is known to be a multicomponent system that always involves enzymes of the plasma membrane and those in the cytoplasm.. The PTS system uses active transport.

4.3E: Group Translocation - Biology LibreTexts

Key Points. PEP is known as a multi-component system that always involves enzymes of the plasma membrane and those in the cytoplasm. An example of this transport is found in E. coli cells.

What is a translocation?

Translocation is a type of chromosomal abnormality in which a chromosome breaks and a portion of it reattaches to a different chromosome. Chromosomal translocations can be detected by analyzing karyotypes of the affected cells.

What is a translocation in a fusion product?

A translocation is a chromosomal abnormality whereby there's a break in the chromosome, one particular chromosome, and that chromosome will then fuse to a different chromosome. And then you have what we call a fusion product. Chromosomal translocations are typically seen in cases of leukemia, like, for instance, in acute myeloid leukemia.

What is chromosomal translocation?

Chromosomal translocations are typically seen in cases of leukemia, like, for instance, in acute myeloid leukemia. For instance, you have different types of chromosomal translocation where part of Chromosome 8, for instance, will break off and fuse with part of Chromosome 11, so you have what we call an 8/11 translocated product.

What is Group Translocation?

Group translocation is another form of active transport in which substances are subjected to covalent modification during the movement across the membrane. Phosphorylation is the main modification undergone by transported substances. During phosphorylation, a phosphate group is transferred from one molecule to another. Phosphate groups are joined by high energy bonds. Hence, when a phosphate bond breaks, a relatively large amount of energy is released and is used for the active transport. Phosphate groups are added to the molecules which enter the cell. Once they cross the cell membrane, they are returned to the unmodified form.

What is the difference between Active Transport and Group Translocation?

Active transport is the movement of ions or molecules through a semipermeable membrane from a lower concentration to a higher concentration, consuming energy.

What is active transport?

Active transport is a method of transporting molecules across the semipermeable membrane against the concentration gradient or electrochemical gradient by utilizing the energy released from ATP hydrolysis. There are numerous situations where cells require certain substances such as ions, glucose, amino acids, etc. at higher or proper concentrations. In these occasions, active transport carries substances from a lower concentration to a higher concentration against the concentration gradient utilizing energy and accumulates inside the cells. Therefore, this process is always associated with a spontaneous exergonic reaction such as ATP hydrolysis, which provides energy to work against the positive Gibbs energy of the transportation process.

How do molecules move in and out of cells?

Molecules pass in and out from the cells via cell membranes. The cell membrane is a selectively permeable membrane which controls the movement of molecules. Molecules naturally move from a higher concentration to a lower concentration along the concentration gradient. It occurs passively without an energy input.

What is the process of molecules traveling across the membrane?

This process requires an energy input, which is known as active transport.

When molecules are required to travel from a lower concentration to a higher concentration against the concentration gradient, it is necessary?

When the molecules are required to travel from a lower concentration to a higher concentration against the concentration gradient, it is necessary to provide an energy input. The movement of ions or molecules across a semipermeable membrane against the concentration gradient with the aid of proteins and energy is known as active transport.

What happens to a phosphate group during phosphorylation?

During phosphorylation, a phosphate group is transferred from one molecule to another. Phosphate groups are joined by high energy bonds. Hence, when a phosphate bond breaks, a relatively large amount of energy is released and is used for the active transport. Phosphate groups are added to the molecules which enter the cell.

What is PEP group translocation?

PEP group translocation, also known as the phosphotransferase system or PTS, is a distinct method used by bacteria for sugar uptake where the source of energy is from phosphoenolpyruvate ( PEP ). It is known to be a multicomponent system that always involves enzymes ...

Where is the phosphoryl group transferred to?

The phosphoryl group is transferred to the Enzyme E I ( EI ), Histidine Protein ( HPr, Heat-stable Protein) and Enzyme E II ( EII) to a conserved histidine residue, whereas in the Enzyme E II B ( EIIB) the phosphoryl group is usually transferred to a cysteine residue and rarely to a histidine.

What is the role of phosphotransferase in bacterial transport?

The phosphotransferase system is involved in transporting many sugars into bacteria, including glucose, mannose, fructose and cellobiose. PTS sugars can differ between bacterial groups, mirroring the most suitable carbon sources available in the environment every group evolved. In Escherichia coli, there are 21 different transporters (i.e. IIC proteins, sometimes fused to IIA and/or IIB proteins, see figure) which determine import specificity. Of these, 7 belong to the fructose (Fru) family, 7 belong to the glucose (Glc) family, and 7 belong to the other PTS permease families.

What is the PTS system?

The PTS system uses active transport. After the translocation across the membrane, the metabolites transported are modified. The system was discovered by Saul Roseman in 1964. The bacterial phosphoenolpyruvate:sugar phosphotransferase system (PTS) transports and phosphorylates its sugar substrates in a single energy-coupled step.

How many transporters are there in Escherichia coli?

In Escherichia coli, there are 21 different transporters (i.e. IIC proteins, sometimes fused to IIA and/or IIB proteins, see figure) which determine import specificity. Of these, 7 belong to the fructose (Fru) family, 7 belong to the glucose (Glc) family, and 7 belong to the other PTS permease families.

What is the benefit of transforming glucose into glucose-6-phosphate?

The benefit of transforming glucose into glucose-6-phosphate is that it will not leak out of the cell, therefore providing a one-way concentration gradient of glucose. The HPr is common to the phosphotransferase systems of the other substrates mentioned earlier, as is the upstream EI.

Which PTS is the same as the glucose PTS in E. coli?

subtilis. The pathway can be read from right to left, with glucose entering the cell and having a phosphate group transferred to it by EIIB. The mannose PTS in E. coli has the same overall structure as the B. subtilis glucose PTS, i.e. the IIABC domains are fused into one protein.

What is the name of the compound that is added to the compound being transported?

A phosphate group is added to the compound being transported

Which type of gradient is responsible for transport across the outer membrane?

transport across outer membrane powered by the proton gradient

What is the heme receptor that binds to heme and transports it in to the cell?

Hug A is a heme receptor that binds to heme and transports it in to the cell; Ton B (an inner membrane protein) contacts Hug A releasing the plug (in Hug A ) carrying heme into the periplasm

Which membrane is facilitated diffusion?

facilitated diffusion through a porin on the outer membrane and group translocation across the inner membrane

What is group translocation?

group translocation A mechanism that is widely utilized for the transportation of sugars across bacterial membranes and perhaps those of some higher cells. A donor compound is used to activate sugar molecules through the provision of a high-energy phosphate group. The activated sugar can thus more readily traverse the membrane.

What is a donor compound?

A donor compound is used to activate sugar molecules through the provision of a high-energy phosphate group. The activated sugar can thus more readily traverse the membrane. A number of membrane proteins have been implicated in the transfer process. Pick a style below, and copy the text for your bibliography.

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Key Difference – Active Transport vs Group Translocation

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Molecules pass in and out from the cells via cell membranes. The cell membrane is a selectively permeable membrane which controls the movement of molecules. Molecules naturally move from a higher concentration to a lower concentration along the concentration gradient. It occurs passively without an energy input. Ho…
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What Is Active Transport?

  • Active transport is a method of transporting molecules across the semipermeable membrane against the concentration gradient or electrochemical gradient by utilizing the energy released from ATP hydrolysis. There are numerous situations where cells require certain substances such as ions, glucose,amino acids, etc. at higher or proper concentrations. In these occasions, active …
See more on differencebetween.com

What Is Group Translocation?

  • Group translocation is another form of active transport in which substances are subjected to covalent modification during the movement across the membrane. Phosphorylationis the main modification undergone by transported substances. During phosphorylation, a phosphate group is transferred from one molecule to another. Phosphate groups are joined by...
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Summary – Active Transport vs Group Translocation

  • The cell membrane is a selectively permeable barrier, which facilitates the passage of ions and molecules. Molecules move from a high concentration to a low concentration along the concentration gradient. When the molecules are required to travel from a lower concentration to a higher concentration against the concentration gradient, it is necessary to provide an energy inp…
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1.Group Translocation | Encyclopedia.com

Url:https://www.encyclopedia.com/plants-and-animals/zoology-and-veterinary-medicine/zoology-general/group-translocation

10 hours ago  · group translocation A mechanism that is widely utilized for the transportation of sugars across bacterial membranes and perhaps those of some higher cells. A donor …

2.Translocation - Genome.gov

Url:https://www.genome.gov/genetics-glossary/Translocation

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3.Difference Between Active Transport and Group …

Url:https://www.differencebetween.com/difference-between-active-transport-and-vs-group-translocation/

14 hours ago  · Group translocation is an active transport mechanism in which molecules are chemically modified during the movement across the membrane. Chemical Modification. …

4.PEP group translocation - Wikipedia

Url:https://en.wikipedia.org/wiki/PEP_group_translocation

19 hours ago  · 00:28. A translocation, as related to genetics, occurs when a chromosome breaks and the (typically two) fragmented pieces re-attach to different chromosomes. The detection …

5.Microbiology: Transport Flashcards | Quizlet

Url:https://quizlet.com/124825259/microbiology-transport-flash-cards/

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6.What Are Translocations? What Disorders Do They …

Url:https://www.webmd.com/children/what-are-translocations

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7.Microbio Exam 1 Part A Flashcards | Quizlet

Url:https://quizlet.com/26660632/microbio-exam-1-part-a-flash-cards/

26 hours ago Translocations, in genetics, happen when chromosomes break and the pieces attach to other chromosomes. This mixing of genetic material has important results. The resultant …

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