Precautions
What are side effects of Ranexa?
- dizziness,
- spinning sensation,
- nausea,
- vomiting,
- stomach pain,
- constipation,
- headache,
- dry mouth,
What are side effects of Ranexa?
You can take ranolazine (Ranexa) with or without food. Swallow the tablets whole. Do not crush, break, or chew them, as the medication will not work correctly. Let your provider know if you have difficulty swallowing pills. Ranolazine (Ranexa) can cause dizziness. Avoid driving or operating machinery until you know how this medication affects you.
Can Ranexa be taken without food?
Ranolazine doesn’t alter heart rate or blood pressure. Ranolazine is used as a second-line medicine in addition to other angina medicines. Ranexa tablets are known as ‘prolonged-release’ tablets.
Does Ranexa affect blood pressure?
Ranexa (ranolazine) is used to treat chronic angina (chest pain). It works by improving blood flow to help the heart work more efficiently. Ranexa is not for use during an acute (emergency) attack of angina. Ranexa may also be used for purposes not listed in this medication guide. Warnings. You should not take Ranexa if you have cirrhosis of ...
How does Ranexa work for treating angina?
Does Ranexa affect blood pressure?
Ranolazine, a piperazine derivative sold under the trade name Ranexa, is a well‐tolerated medication that selectively inhibits the late sodium current. Additionally, ranolazine has beneficial metabolic properties and does not affect heart rate or blood pressure.
Does Ranexa work immediately?
Ranolazine (Ranexa) doesn't work very fast, and usually takes about 4 hours for peak effect. Faster-acting medications, like Nitrostat (nitroglycerin sublingual tablets), are better for quickly treating chest pain that has already started.
How does Ranexa make you feel?
Dizziness, headache, lightheadedness, nausea, tiredness, and constipation may occur. If any of these effects last or get worse, notify your doctor or pharmacist promptly. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.
What time of day should you take Ranexa?
You can take ranolazine either before or after a meal. Swallow the tablet whole (without chewing or crushing it) with a drink of water. If you forget to take a dose at your usual time, take it when you remember.
Is Ranexa good for the heart?
Calcium ions normally cause the heart muscle to contract. By reducing the flow of calcium into the cells, ranolazine is thought to help the heart to relax, improving blood flow to the heart muscle and relieving the symptoms of angina pectoris.
Does ranolazine give you energy?
Indirect calorimetry assessed at 3 weeks after treatment revealed that ranolazine augments energy expenditure, as whole-body O2 consumption rates normalized to lean body mass were markedly increased (Figure 4A).
Does ranexa make you tired?
This medicine may cause some people to become dizzy, lightheaded, drowsy, or less alert than they are normally.
What drugs should not be taken with Ranexa?
Do not use RANEXA with strong CYP3A inhibitors, including ketoconazole, itraconazole, clarithromycin, nefazodone, nelfinavir, ritonavir, indinavir, and saquinavir [see CONTRAINDICATIONS, CLINICAL PHARMACOLOGY].
Does ranexa lower blood sugar?
Ranolazine is a drug used for the treatment of angina. Studies have shown that ranolazine lowered blood glucose in patients with long-term angina.
Is Ranexa a good drug?
Ranexa has been shown to significantly improve the amount of time patients with stable angina are able to exercise before developing symptoms. It was approved by the Food and Drug Administration (FDA) in 2008 as a first-line treatment for angina.
Is Ranexa an anti inflammatory?
Ranolazine demonstrated significant anti-inflammatory activity in acute and subacute models of inflammation and needs further evaluation for its use in reducing atherosclerosis.
What medication can replace Ranexa?
Metoprolol.Isosorbide mononitrate.Amlodipine.Nitrostat.Ranolazine.Enoxaparin.
How long does it take for heart medication to take effect?
It usually starts to work after about 1 hour. But it will take days or weeks for it to reach its full effect.
Does Ranexa make you sleepy?
This medicine may cause some people to become dizzy, lightheaded, drowsy, or less alert than they are normally.
Can Ranexa be used as needed?
It can be increased to two tablets twice daily as needed based on clinical symptoms. Ranolazine can be taken with or without meals and should be swallowed whole and not crushed, broken, or chewed. Grapefruit juice or products should be avoided.
What drugs should not be taken with Ranexa?
Drug InteractionsAmoxapine.Amprenavir.Atazanavir.Bepridil.Carbamazepine.Cisapride.Clomipramine.Colchicine.More items...•
Before Taking This Medicine
You should not take Ranexa if you are allergic to ranolazine, or if you have cirrhosis of the liver.Many other drugs can interact with ranolazine a...
How Should I Take Ranexa?
Take Ranexa exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose t...
Ranexa Dosing Information
Usual Adult Dose of Ranexa for Angina Pectoris:Initial dose: 500 mg orally twice dailyMaintenance dose: 500 mg to 1000 mg orally twice daily. Maxim...
What Happens If I Miss A Dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to...
What Happens If I Overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.Overdose can cause nausea, vomiting, numbness or tingling, dizzines...
What Should I Avoid While Taking Ranexa?
Ranexa may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.Grapefruit and grapefruit juice...
What Other Drugs Will Affect Ranexa?
Many drugs can interact with Ranexa. Below is just a partial list. Tell your doctor if you are using: 1. aprepitant (Emend); 2. arsenic trioxide (T...
What is Ranexa?
Ranexa (ranolazine) is used to treat chronic angina (chest pain). It works by improving blood flow to help the heart work more efficiently.
How should I take Ranexa?
Take Ranexa exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended.
What other drugs will affect Ranexa?
The following drugs can interact with ranolazine and should not be used at the same time. Your doctor may need to change your treatment plan if you use any of the following drugs:
What happens if you are allergic to Ranexa?
Get emergency medical help if you have any signs of an allergic reaction to Ranexa: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Can you take Ranexa if you have cirrhosis?
You should not take Ranexa if you have cirrhosis of the liver. Serious drug interactions can occur when certain medicines are used together with ranolazine. Tell each of your healthcare providers about all medicines you use now, and any medicine you start or stop using.
How to treat chronic angina with Ranexa?
Chronic angina is often treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication.
What to tell your doctor before taking Ranexa?
Before you take Ranexa, tell your doctor about all of your medical conditions, especially if you have a personal or family history of Long QT syndrome.
How does Ranexa work?
How does it work? Ranexa tablets contain the active ingredient ranolazine, which is a type of medicine called an antianginal medicine. It is used to treat angina. The pain of angina is caused by too little oxygen reaching the heart when the heart rate increases and its workload increases, such as during exercise.
What is Ranexa tablet?
Ranexa tablets are known as ‘prolonged-release’ tablets. They are designed to release the medicine slowly and continuously over several hours, to provide a steady amount of medicine in the blood.
How can this medicine affect other medicines?
It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before taking any new medicines while taking this one, to make sure that the combination is safe.
What is a pectoris medicine?
What is it used for? Treatment of chronic stable angina pec toris. This medicine is used when medicines such as beta-blockers and/or calcium antagonists have not successfully controlled the symptoms of angina, or have caused unacceptable side effects.
Does Ranexa contain lactose?
Ranexa 750mg tablets contain lactose and should not be used by people with rare hereditary problems of galactose intolerance, the Lapp-lactase deficiency or glucose-galactose malabsorption.
Can you chew ranolazine?
The tablets should not be broken, chewed or crushed, as this can damage the prolonged-release action. You should avoid eating grapefruit or drinking grapefruit juice while taking this medicine, as grapefruit may affect the metabolism of ranolazine by your liver and could increase the risk of getting side effects.
Can Ranexa be taken for angina?
Ranexa tablets need to be taken on a regular basis to help prevent angina attacks. This medicine should not be used to treat an angina attack, as it won’t work for this purpose.
How Does It Work?
Ranolazine is used to treat a certain type of chest pain (chronic stable angina).
May Treat: Anginal pain in coronary artery disease
Drug Class: Antianginal and Anti-ischemic Agents, Non-hemodynamic
Availability: Prescription Required
Pregnancy: Consult a doctor before using
Lactation: Consult a doctor before using
May Treat: Anginal pain in coronary artery disease
Drug Class: Antianginal and Anti-ischemic Agents, Non-hemodynamic
Availability: Prescription Required
Pregnancy: Consult a doctor before using
Lactation: Consult a doctor before using
Alcohol: Limit intake while taking this medication
Driving: May cause drowsiness or dizziness. Use caution
Manufacturer: GILEAD SCIENCES
- If available, read the patient package insert
- Do not chew or crush. OK to split tablet if scored
- Do not use to stop angina attack. Use regularly.
- If available, read the patient package insert
- Do not chew or crush. OK to split tablet if scored
- Do not use to stop angina attack. Use regularly.
- May make you dizzy. Use caution when driving.
- Avoid taking grapefruit juice/grapefruit with med
- Tell doctor if fainting or faintness occurs.
- Review all drugs you are taking with your doctor
- MD may need to reduce the dose before you stop it.
How Do I Take It?
Warning!
Use with Caution in
Not to Be Used in
Pregnancy and Breastfeeding
- Ranexa tablets need to be taken on a regular basis to help prevent angina attacks. This medicine should not be used to treat an angina attack, as it won’t work for this purpose.
- Ranexa tablets should be taken twice a day (morning and evening), either with or without food.
- Ranexa tablets should be swallowed whole with a drink of water. The tablets should not be broken, chewed or crushed, as this can damage the prolonged-release action.
- Ranexa tablets need to be taken on a regular basis to help prevent angina attacks. This medicine should not be used to treat an angina attack, as it won’t work for this purpose.
- Ranexa tablets should be taken twice a day (morning and evening), either with or without food.
- Ranexa tablets should be swallowed whole with a drink of water. The tablets should not be broken, chewed or crushed, as this can damage the prolonged-release action.
- You should avoid eating grapefruit or drinking grapefruit juice while taking this medicine, as grapefruit may affect the metabolism of ranolazine by your liver and could increase the risk of gettin...
Side Effects
- You will be given a patient alert card with this medicine. This contains important information about this medicine that you should read, as well as details of your medicines and doses. You should s...
- If you experience side effects such as feeling dizzy or sick, or being sick while taking this medicine, you should tell your doctor. Your dose may need reducing. If a lower dose doesn’t i…
- You will be given a patient alert card with this medicine. This contains important information about this medicine that you should read, as well as details of your medicines and doses. You should s...
- If you experience side effects such as feeling dizzy or sick, or being sick while taking this medicine, you should tell your doctor. Your dose may need reducing. If a lower dose doesn’t improve the...
- • This medicine may cause dizziness, blurred vision, confusion or hallucinations and so may affect your ability to drive or operate machinery. You should not drive or operate machinery until you kn...
- Ranexa 750mg tablets contain E102, which may cause allergic reactions.
How Can This Medicine Affect Other Medicines?
- Elderly people.
- People who weigh 60kg or less.
- Heart failure.
- People with a personal or family history of an abnormal heart rhythm seen on a heart monitoring trace (ECG) as a 'prolonged QT interval'.
Other Medicines containing The Same Active Ingredient
- The safety and efficacy of this medicine in children has not been established and the manufacturer does not recommended it for children under 18 years of age.
- People with moderate to severely decreased liver function.
- People with severely decreased kidney function.
- Pregnancy.