Precautions
The usual total treatment course of Venofer is 1000 mg. Venofer treatment may be repeated if iron deficiency reoccurs. Administer Venofer 200 mg undiluted as a slow intravenous injection over 2 to 5 minutes or as an infusion of 200 mg in a maximum of 100 mL of 0.9% NaCl over a period of 15 minutes.
How long does it take to administer Venofer?
Each mL contains 20 mg of elemental iron. Administer Venofer 100 mg undiluted as a slow intravenous injection over 2 to 5 minutes, or as an infusion of 100 mg diluted in a maximum of 100 mL of 0.9% NaCl over a period of at least 15 minutes, per consecutive hemodialysis session [see How Supplied/Storage and Handling ( 16.2 ).]
How much iron is in a Venofer infusion?
Ferritin < 200 AND iron saturation < 20% Venofer®dosage: Usually 300 mg in 250mL NS by IV infusion over 2 h. If weight < 50 kg (110 lb), consider a 200 mg dose to reduce infusion-related side effects.
What is the recommended dose of Venofer® for adults?
Most reactions associated with intravenous iron preparations occur within 30 minutes of the completion of the infusion. Venofer may cause clinically significant hypotension. Monitor for signs and symptoms of hypotension following each administration of Venofer.
How long does it take for Venofer to cause hypotension?
How long does it take to infuse Venofer?
Administer Venofer 200 mg undiluted as a slow intravenous injection over 2 to 5 minutes or as an infusion of 200 mg in a maximum of 100 mL of 0.9% NaCl over a period of 15 minutes.
How long is Venofer good for once mixed?
7-day Stability After Dilution. Venofer offers 7-day stability at controlled room temperature in both plastic syringes and IV admixtures diluted with 0.9% Sodium Chloride Injection (NaCl), avoiding potential waste.
How quickly does Venofer increase hemoglobin?
Due to iron metabolic pathways, a rise in reticulocyte count will occur during the second week and thereafter, provided bleeding is not excessive, one can expect a rise in haemoglobin of approximately 1.5g/week.
Can you push Venofer?
Administer Venofer only intravenously by slow injection or by infusion. The dosage of Venofer is expressed in mg of elemental iron.
How fast can you run IV iron?
Doses up to 1000 mg can be administered in 15 minutes, but those >1000 mg should be administered over 30 minutes.
How long does it take to infuse iron IV?
An iron infusion can take up to 3 or 4 hours. You should expect to remain seated for this time. In some cases, the infusion may take a little longer, depending on the level of treatment your doctor thinks you need. The slow infusion rate helps prevent complications.
What is the fastest way to get your hemoglobin up?
1. Increasing iron intakemeat and fish.soy products, including tofu and edamame.eggs.dried fruits, such as dates and figs.broccoli.green leafy vegetables, such as kale and spinach.green beans.nuts and seeds.More items...
Can you feel immediately better after iron infusion?
How long after my iron infusion will I start to feel better? Your iron levels will be restored directly right after the infusion, however, it can take up to two weeks before you start to notice a difference and feel better.
What hemoglobin level requires iron transfusion?
But 7 to 8 g/dL is a safe level. Your doctor should use just enough blood to get to this level. Often, one unit of blood is enough. Some doctors believe that hospital patients who fall below 10 g/dL should get a blood transfusion.
Is Venofer IV push?
The usual adult total treatment course of Venofer is 1000 mg....Adult CKD Patients. 1.IV Push100 mg over 2 to 5 minHemodialysis-dependent chronic kidney disease (HDD-CKD)* Consecutive dialysis sessions200 mg over 2 to 5 minNon-dialysis-dependent chronic kidney disease (NDD-CKD) Five occasions over 14 days
What happens after Venofer infusion?
Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. Pain, swelling, or redness at the injection site may occur. If these effects continue or worsen, tell your doctor.
Can you give too much IV iron?
However, excessive IV iron use, combined with blood transfusions, may expose patients to iron overload. More subtle safety concerns may also be related to IV iron, such as worsening of atherosclerosis and oxidative stress and increased risk of infection. Labile iron may also cause parenchymal damage by itself.
Do iron infusions have to be a week apart?
You may need one to three sessions of iron infusions, which are usually given about one week apart. The dosage and frequency of iron infusion will depend on which intravenous iron product your doctor prescribed and on the severity of your anemia.
Does iron infusion need to be refrigerated?
Oral iron should not be used for at least one week after intravenous iron. A 2mL ampoule of iron polymaltose (318mg) contains 100mg of elemental iron. Store below 25°C. Do not refrigerate or freeze vial (diluted solutions of 2-5mg/mL are stable for 24 hours at 2- 8°C).
When should you hold Venofer?
a. If hemoglobin ≥12, iron saturation >30%, and ferritin >800, hold Venofer.
How long can you take iron syrup?
Blood counts return to normal after 2 months of iron therapy for most people. You should continue taking supplements for another 6 to 12 months to build up the body's iron stores in the bone marrow. Iron is absorbed the best on an empty stomach.
Before Taking This Medicine
You should not be treated with Venofer if you have ever had an allergic reaction to an iron injection.To make sure Venofer is safe for you, tell yo...
Venofer Dosing Information
Usual Adult Dose of Venofer for Iron Deficiency Anemia:Hemodialysis Dependent Chronic Kidney Disease (HDD-CKD):5 mL (100 mg elemental iron) undilut...
What Should I Avoid While Using Venofer?
Follow your doctor's instructions about any restrictions on food, beverages, or activity while you are using Venofer injection.
What Other Drugs Will Affect Venofer?
Treatment with Venofer injections can make it harder for your body to absorb iron medications you take by mouth. Tell your doctor if you are taking...
Indications and Usage for Venofer Injection
Venofer is indicated for the treatment of iron deficiency anemia (IDA) in patients with chronic kidney disease (CKD).
Venofer Injection Dosage and Administration
Venofer must only be administered intravenously either by slow injection or by infusion. The dosage of Venofer is expressed in mg of elemental iron. Each mL contains 20 mg of elemental iron.
Warnings and Precautions
Serious hypersensitivity reactions, including anaphylactic-type reactions, some of which have been life-threatening and fatal, have been reported in patients receiving Venofer. Patients may present with shock, clinically significant hypotension, loss of consciousness, and/or collapse.
Adverse Reactions
The following clinically significant adverse reactions are described elsewhere in the labeling:
Drug Interactions
Venofer may reduce the absorption of concomitantly administered oral iron preparations.
USE IN SPECIFIC POPULATIONS
Published studies on intravenous iron sucrose treatment after the first trimester of pregnancy have not shown adverse maternal or fetal outcomes (see Data). Available reports of intravenous iron sucrose use in pregnant women during the first trimester are insufficient to assess the risk of major birth defects and miscarriage.
Overdosage
No data are available regarding overdosage of Venofer in humans. Excessive dosages of Venofer may lead to accumulation of iron in storage sites potentially leading to hemosiderosis. Do not administer Venofer to patients with iron overload [see Warnings and Precautions ( 5.3 )].
What is Venofer?
Venofer injection contains iron sucrose, a form of the mineral iron. Iron is important for many functions in the body, especially for the transport of oxygen in the blood.
Warnings
You should not receive Venofer if you have ever had an allergic reaction to an iron injection, or if you have iron overload (the buildup of excess iron) or hemochromatosis.
Before taking this medicine
You should not be treated with this medicine if you have ever had an allergic reaction to an iron injection.
How is Venofer given?
Venofer is given as an infusion into a vein. A healthcare provider will give you this injection.
What happens if I miss a dose?
Call your doctor for instructions if you miss an appointment for your Venofer injection.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while using Venofer?
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.