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how much phenobarbital can i give my dog

by Prof. Merl Muller II Published 2 years ago Updated 2 years ago
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Phenobarbital for Dogs: The Golden Standard for Managing Canine Seizures

  • Phenobarbital for Dogs Dosage The recommended starting dose of Phenobarbital for dogs is 1.1 milligrams per pound of body weight (2.5 milligrams per kilograms) every 12 hours (twice a day). ...
  • Phenobarbital for Dogs Usage Guidelines Phenobarbital is available in several oral forms (tablets, capsules, liquids, treat chewables, and pastes). ...
  • Alternatives for Phenobarbital for Dogs ...
  • Sources ...

Typically, phenobarbital is started at a dose of 2.5 mg per kilogram of body weight every 12 hours. Depending on how your dog responds, this dose may be raised or lowered. Timing of each dose is very important as missing even one dose can potentially trigger a seizure.May 21, 2021

Full Answer

How much phenobarbital can I give my Dog?

The most commonly recommended dose in dogs is 2-3 mg phenobarbital per kilogram of body weight given every 12 hours. In some cases, it helps to divide the daily dose into three equal doses given every 8 hours. Each patient is different and only the attending veterinarian should make specific recommendations.

Can you give a dog Taking phenobarbital Advil?

Veterinarians will not prescribe Advil for dogs because it is simply too toxic for their kidneys and stomach. There are much better natural alternatives that are less likely to cause side effects. Never give a dog Advil unless you are specifically instructed to do so by a veterinarian.

How long does phenobarbital take to work in dogs?

It usually takes a couple of weeks before Phenobarbital for dogs starts working. However, there can be noticeable improvements after several doses. Phenobarbital has a long elimination half-life but needs time to achieve steady and therapeutic blood levels.

Does phenobarbital make dogs aggressive?

Your veterinarian will adjust your dog's phenobarbital dose based on blood level testing and seizure control. Some dogs on phenobarbital become hyperactive and aggressive. Other adverse effects include diarrhea, vomiting, poor appetite, and itching. During prolonged use, phenobarbital in dogs can damage the liver.

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What is the maximum amount of phenobarbital for dogs?

The initial dosage (dogs only) is 5–15 mg/kg/day in three divided doses, increased over time to a maximum of 35 mg/kg/day. Effective serum levels are determined by the serum level of phenobarbital (15–45 mcg/mL).

Can a dog overdose on phenobarbital?

The average dosage of Phenobarbital for a dog Mandy's size would be 4 tablets twice daily. Mandy had eaten a ninety times overdose! Symptoms of over dosage of Phenobarbital are ataxia (drunk acting), lethargy, sedation, recumbency (inability to stand), depression, hypothermia (decreased temperature), coma, and death.

Why is my dog still having seizures while on phenobarbital?

While the majority of dogs respond very well to Phenobarbital and/or potassium bromide, there are a few dogs that will continue to have a high seizure frequency despite having adequate serum levels of these medications, and are called “refractory”. For these dogs newer anticonvulsants may help.

Can I give my dog phenobarbital 3 times a day?

The most commonly recommended dose in dogs is 2-3 mg phenobarbital per kilogram of body weight given every 12 hours. In some cases, it helps to divide the daily dose into three equal doses given every 8 hours. Each patient is different and only the attending veterinarian should make specific recommendations.

Does phenobarbital have to be given exactly every 12 hours?

Phenobarbital Dosage for Dogs Generally, this medication should be given every 12 hours, and it is important not to miss a dose. If this happens, do NOT give your dog two doses at once–skip the missed dose and continue with the regularly scheduled dosage.

How long does phenobarbital take to work in dogs?

Therefore, the recommended dosage is every 12 to 24 hours, and it will take about 7-14 days to reach a consistent level of phenobarbital in the dog's system (steady state). In dogs, phenobarbital drug levels often decrease even when the dose is constant.

What stops dogs from having seizures?

Drugs such as potassium bromide or phenobarbital can help control seizures. As always, ask your veterinarian for recommendations for your dog's specific problem. Alternative therapies are sometimes helpful.

How many seizures is too many for a dog?

If your dog had a first-time seizure or has multiple seizures within 24 hours, consider it an emergency. “Seek veterinary care immediately if your pet does not have a history of seizures and is having cluster seizures or prolonged grand mal seizures,” suggests Dr. Frione.

What not to feed a dog that has seizures?

What toxins cause seizures in dogs? Food that causes seizures. According to the ASPCA, caffeine, dark chocolate, mushrooms, theobromine, ethanol, and xylitol can cause your dog's seizures. Theobromine is what makes chocolate toxic to dogs.

What can I give my dog instead of phenobarbital?

In our experience, clorazepate is a moderately effective alternative anticonvulsant drug. In dogs already receiving phenobarbital, maintaining the correct dosage of clorazepate can be troublesome. Another potential use for clorazepate is for short-term treatment in dogs experiencing cluster seizure episodes.

Will phenobarbital make my dog sleepy?

Common side effects in dogs include anxiety, agitation, lethargy, or sedation when therapy is started, and increased thirst, urination, and appetite or elevated liver enzymes on bloodwork are possible. Side effects such as incoordination may indicate a dose that is too high.

How much phenobarbital is an overdose?

Phenobarbital Overdose A lethal dose of phenobarbital is 6-10 grams, which a person may have in their medicine cabinet if they have a prescription. As a daytime sedative, a doctor may prescribe anywhere from 30 mg to 120 mg. As an insomnia treatment, an individual could take as much as 320 mg.

What happens with phenobarbital overdose?

Symptoms of a phenobarbital overdose may include: Blurred or double vision, rapid side-to-side movement of eyes (nystagmus) Coma (decreased level of consciousness and lack of responsiveness) Confusion.

How does phenobarbital cause death in dogs?

Phenobarbital overdose in dogs usually occurs as a result of accidental ingestion of the drug. It is a serious intoxication in which the following symptoms can occur: Central nervous system depression: can range from drowsiness to coma. Respiratory problems: can cause the dog to stop breathing in severe intoxication.

What is a toxic level of phenobarbital?

If phenobarbitone serum concentrations performed: >172-258 micromol/L – may be expected to cause toxic effects. >345-650 micromol/L – potential to be lethal.

What is phenobarbital used for?

Barbiturate drugs have been around for many decades; they were widely used in humans in the 1960s and 1970s to treat anxiety, insomnia, and seizures. For dogs, Phenobarbital is commonly used to treat se izure disorders such as epilepsy. It is a very effective drug ...

Are there any natural alternatives to Phenobarbital?

Hemp-derived CBD was recently made legal for sale in the US, thanks to the 2018 farm bill.

Can phenobarbital cause liver damage?

Weight gain. Phenobarbital can cause liver damage (such as scarring in the liver) after prolonged use (over three months). In rare cases, it can even cause liver failure, which is why frequent blood tests are necessary for your vet to monitor the liver function.

Can phenobarbital be taken with Keppra?

The effect of Phenobarbital can either be increased or decreased when combined with many other drugs, including Keppra for dogs or Gabapentin for dogs. You should always consult your vet if your dog is taking one or more medications before being put on Phenobarbital to avoid potentially harmful side effects.

Can phenobarbital cause depression in dogs?

Overdose can cause depression in the nervous system. Therefore it is essential to give Phenobarbital to your dog as prescribed and instructed by your vet. Blood tests by your vet are essential every 2-6 months to monitor the level of Phenobarbital in your dog’s blood to make sure your dog is taking the proper and safe dosage.

Is phenobarbital safe?

While Phenobarbital is a relatively safe medication, side effects can occur. Side effects to watch out for include:

Does CBD oil help with seizures?

A small 2016/2017 study by Colorado State University found that CBD was able to reduce the number of seizures in 89% of dogs when used in combination with traditional anti- seizure medication. The side effects for CBD oil for seizures in dogs are relatively minimal and are usually reversible by merely reducing the dose.

What is phenobarbital used for?

Uses Of Phenobarbital For Dogs. Phenobarbital is primarily used to treat seizure disorders such as epilepsy in dog s. Diazepam, more commonly known as Valium, is another anticonvulsant drug that vets sometimes prescribe to dogs for seizures. There are other drugs available that have fewer side effects, though they are more expensive.

What is the best medication for dogs with epilepsy?

Phenobarbital is one of the most commonly used drugs to treat epilepsy and other seizure disorders in dogs. It is also known by the brand names Luminal and Barbita. Phenobarbital works by decreasing and stabilizing neuron activity in the brain.

How much phenobarbital is in a grain?

Overdose can result in nervous system depression. Phenobarbital often comes in doses measured in “grains” rather than milligrams. One grain is equal to about 60 mg, and the drug is available in 1/4 grain, 1/2 grain, 1 grain, and 100 mg tablets. It is also available in an injectable form, which comes in 65 mg/ml and 130 mg/ml doses.

What are the side effects of a sulfate based sulfate based s?

Anxiety. Restlessness. Loss of coordination. Increased thirst or appetite. Weight gain. Increased urination. Anemia. Liver damage (long-term use) If you see concerning side effects in your dog, then consult your veterinarian, as they may wish to alter the dosage or seek an alternative form of treatment.

Is phenobarbital safe for dogs?

Phenobarbital is generally safe for dogs when prescribed in the correct dosage, however there are some short-term and long-term side effects that may occur. Short-term side effects typically clear up in a few weeks, and your veterinarian will have to monitor your dog for long-term side effects if they take the drug for an extended period of time.

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Can phenobarbital be used for seizures?

There are other drugs available that have fewer side effects, though they are more expensive. Phenobarbital is one of the most commonly used drugs to treat seizures in dogs because it is so effective and inexpensive compared to other options. Occasionally, veterinarians can use phenobarbital as a sedative, as well.

What is Phenobarbital for Dogs?

Phenobarbital belongs to a family of drugs called the barbiturates. In particular, phenobarbital is a long-acting barbiturate that has an anticonvulsant action. This simply means the drug stays in the body a long-term and helps reduce seizure activity.

What is the best anti-seizure medication for epilepsy?

Phenobarbital was one of the first anti-seizure medications to be developed. With a proven track record of effectiveness, your vet is likely to choose it as the drug of choice to manage epilepsy.

What is the best CBD oil for dogs?

When considering a CBD oil look for one, such as Honest Paws, that refines to a high standard. This reduces the risk of accidentally dosing your dog with harsh chemicals, in addition to the CBD.

How long does it take for a dog to have a seizure?

Dogs with epilepsy may have clusters of seizures (a group of fits occurring within 24 – 48 hours) which are mild or severe. The worst fits are when the dog enters a seizure which doesn’t end. This life-threatening development is called status epilepticus.

What is the best combination for phenobarbital?

Combination Therapy: Potassium bromide is often the drug of choice, to add onto phenobarbital treatment. Bromide works in a different way to phenobarbital, so it corrects the problem from a different direction.

What is the abbreviation for cbd?

CBD is an abbreviation of the word cannabidiol. CBD is derived by processing hemp (the rope-like stuff) or cannabis (the recreational drug). Drugs such as cannabis give people a ‘high’ because of the presence of psychoactive substances called tetrahydrocannabinol (THC).

Why do dogs have seizures?

Seizures in dogs can be caused by any number of underlying health conditions. Examples include a liver shunt, toxin ingestion, or a brain tumor. However, when the seizures have been investigated and no underlying cause is found, then and only then is the condition considered to be epilepsy.

What is Phenobarbital for Dogs?

Phenobarbital for dogs is a barbiturate that affects the nervous system in dogs. It’s a depressant that’s also known by the name Luminal or Barbital. Phenobarbital helps to reduce the severity of seizures, as well as the duration of each seizure.

What is CBD Oil for Dogs?

CBD is a component of the cannabis plant that does not have a psychoactive effect when it is free of delta-9- tetrahydrocannabinol (THC). Pet CBD products should contain less than 0.3 % THC, if any at all.

What is the best medicine for dogs with seizures?

Phenobarbital for dogs is a popular, and often- prescribed medication used to treat seizures in dogs. Anticonvulsant drugs like phenobarbital are used to treat seizures in dogs, including those caused by epilepsy. There are also numerous healthier alternatives like CBD for pets without the THC, instead of using phenobarbital for dogs.

How does CBD oil extract?

Extraction of CBD oil takes place via a carbon dioxide process called CO2 extraction. This uses pressurized carbon dioxide to extract the CBD from the entire plant. CO2 functions as a solvent when reaching extreme temperatures, yet because it is under boiling point, it’s cold.

Why do dogs have seizures?

This is caused by seizures induced by viral or infectious diseases, metabolic disorders, nutritional im balances caused by low-quality diets or traumatic injury to pets. Seizures can also be seen in dogs with a thyroid condition.

What breed of dog has epilepsy?

Epilepsy can affect any dog breed, with the most common dog breed affected being the Golden Retriever. It is a seizure disorder that is caused by abnormal electrical patterns in the brain.

Does CBD oil help dogs with seizures?

There are numerous other studies that attribute CBD’s effectiveness in reducing inflammation that is linked to seizure activity in dogs. If your dog is struggling with seizures, or just feeling out of sorts, hemp CBD for pets may be an option. Just recently, Epidiolex was approved by the FDA.

How to calm a dog with a seizure?

If you can, put light pressure on his eyeballs to decrease seizure duration. Be sure to record the duration, severity, and what your pet was doing before and after the seizure occurred. Contact your veterinarian right away.

What are the side effects of phenobarbital?

Because Phenobarbital may also decrease other neurotransmitters, common side effects may include lethargy and loss of coordination, as well as: 1 Increased appetite, which may lead to weight gain 2 Increased thirst and urination 3 Anxiety 4 Anemia

What happens if a dog shakes?

If your dog has ever suddenly twitched or shaken uncontrollably for a short period of time, usually about one-to-several minutes, he may have had a seizure, which is an abnormal burst of electrical activity in the brain. Other signs of a seizure include drooling, chomping, foaming at the mouth, and unconsciousness. If this happens frequently, your dog may have epilepsy. Any dog can have a seizure, but they are more common in breeds such as Labrador Retrievers, German Shepherds, Beagles, and Border Collies.

Why do dogs have seizures?

This drug works by decreasing and stabilizing neuron activity in the brain.

Does phenobarbital cause lethargy?

Because Phenobarbital may also decrease other neurotransmitters, common side effects may include lethargy and loss of coordination, as well as:

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1.The Uses, Dose, and Dangers of Phenobarbital for Dogs

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