
Precautions
Eliquis (apixaban) is good at preventing blood clots that can cause a stroke or heart attack, but it is very expensive. What is Eliquis (apixaban)? Eliquis (apixaban) is an anticoagulant (blood thinner) that works by stopping an enzyme complex called factor Xa.
Is Eliquis (apixaban) good for blood clots?
Generic Eliquis Availability Last updated on May 11, 2021. Eliquis is a brand name of apixaban, approved by the FDA in the following formulation (s): ELIQUIS (apixaban - tablet;oral)
What is the generic name for Eliquis?
Both Eliquis and warfarin are anticoagulant drugs (sometimes called blood thinners ). However, these drugs work differently in your body to prevent blood clots from forming.
Are Eliquis and warfarin the same thing?
Apixaban belongs to a class of anticoagulants called selective Xa inhibitors. It works by inhibiting factor Xa which in turn, decreases blood clot formation to prevent and treat these conditions. How should I take it?
What is apixaban and how does it work?
What is the D90 of apixaban?
Compositions comprising crystalline apixaban particles having a D90 equal to or less than 89 μm, and a pharmaceutically acceptable carrier, are substantially bioequivalent and can be used to for the treatment and/or prophylaxis of thromboembolic disorders.
When was Lactam patent issued?
Lactam-containing compounds and derivatives thereof as factor Xa inhibitors. Patent 6,967,208. Issued: November 22, 2005.
Is Eliquis a generic?
A generic version of Eliquis has been approved by the FDA. However, this does not mean that the product will necessarily be commercially available - possibly because of drug patents and/or drug exclusivity. The following products are equivalent to Eliquis and have been approved by the FDA:
Is Eliquis counterfeit?
Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Eliquis. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy.
Is Eliquis a brand name?
Eliquis is a brand name of apixaban, approved by the FDA in the following formulation (s):
When was Apixaban approved?
Apixaban was approved for medical use in the European Union in May 2011, and in the United States in December 2012. In 2018, it was the 66th most commonly prescribed medication in the United States with more than 12 million prescriptions. In December 2019, generic versions were approved in the United States.
What is the name of the medication that is used to treat a clot in the hip?
Apixaban, sold under the brand name Eliquis among others, is an anticoagulant medication used to treat and prevent blood clots and to prevent stroke in people with nonvalvular atrial fibrillation. Specifically it is used to prevent blood clots following hip or knee replacement and in those with a history of prior clots.
What is Andexanet Alfa?
Andexanet alfa is a Food and Drug Administration (FDA) approved antidote for apixaban in people with uncontrolled and life-threatening bleeding events.
Is Apixaban being used in the NHS?
The NHS is currently trialling the use of apixaban in treating post-recovery COVID-19 patients.
Does Apixaban inhibit thrombin?
Factor Xa catalyzes the conversion of prothrombin to thrombin, the final enzyme in the coagulation cascade that is responsible for fibrin clot formation. Apixaban has no direct effect on platelet aggregation, but by inhibiting factor Xa, it indirectly decreases clot formation induced by thrombin.
Is Apixaban the same as Warfarin?
Apixaban and other anticoagulants ( dabigatran, edoxaban and rivaroxaban) appear equally effective as warfarin in preventing non-hemorrhagic stroke in people with atrial fibrillation and are associated with lower risk of intracranial bleeding.
Who is the FDA approved for Apixaban?
The FDA granted approval of the generic apixaban applications to Micro Labs Limited and Mylan Pharmaceuticals Inc. Please contact the manufacturers for information about the medicine’s availability.
When will Eliquis be released?
For Immediate Release: December 23, 2019. January 10, 2020 Update: This press release was updated to indicate that apixaban was not studied in patients with atrial fibrillation caused by a heart valve problem. The U.S. Food and Drug Administration has approved two applications for the first generics of Eliquis ...
Can apixaban cause a stroke?
There is an increased risk of thrombotic events, which occur when blood clots form inside a blood vessel, or strokes if a patient stops using apixaban too early . Additionally, epidural or spinal hematomas (bleeding outside of blood vessels) may occur in patients treated with apixaban who are receiving neuraxial anesthesia or undergoing spinal puncture. These hematomas may result in long-term or permanent paralysis. Health care professionals should consider these risks when scheduling patients for spinal procedures.
Does Apixaban have a medication guide?
Many of these individuals use anticoagulants or anti-clotting drugs to reduce that risk. Apixaban will be dispensed with a Medication Guide for patients that provides instructions on its use and drug safety information. Health care professionals should counsel patients on signs and symptoms of possible bleeding.
Can you take Apixaban with prosthetic heart valves?
Health care professionals should consider these risks when scheduling patients for spinal procedures. Patients with prosthetic heart valves should not take apixaban. Apixaban was not studied in patients with atrial fibrillation caused by a heart valve problem.
Is Apixaban a generic?
“Today’s approvals of the first generics of apixaban are an example of how the FDA’s generic drug program improves access to lower-cost, safe and high-quality medicines,” said Janet Woodcock, M.D., ...
What is the purpose of aspirin?
Aspirin relieves pain and inflammation and helps to thin the blood. It is used to treat and prevent a wide range of different conditions. Higher dosages are associated with stomach irritation and... View. more.
Does Eliquis require monitoring?
Eliquis reduces the clotting ability of the blood and is used in the treatment and prevention of several medical conditions associated with blood clots. It does not require monitoring, and an... View. more.
What is Eliquis used for?
Uses. Eliquis is approved for use in treating or preventing pulmonary embolism and deep vein thrombosis. It is also used to reduce the risk of systemic embolism and stroke in individuals with nonvalvular atrial fibrillation.
What is the difference between Xarelto and Eliquis?
Eliquis vs Xarelto — What is the Difference? Eliquis and Xarelto have many similar uses and a similar mechanism of action, although Xarelto is used for reducing the risk of cardiovascular events while Eliquis is not. A 2019 scientific review found that Eliquis may provide a safer way of treating acute venous thromboembolism compared to Xarelto.
What is Xarelto rivaroxaban?
Xarelto is an anticoagulant with the generic name rivaroxaban.
Is Eliquis safe for apixaban?
Eliquis has a few contraindications that individuals should be aware of. This medication is not considered suitable for those who have hypersensitivity to apixaban. It should also not be used in patients who have active pathological bleeding or those who are having spinal punctures done or getting epidural or spinal anesthesia, since it can increase the risk of spinal hematoma. This medication has warnings for other conditions as well, such as those who have prosthetic heart valves.
Is Xarelto contraindicated?
Xarelto is contraindicated in individuals who have active pathological bleeding and those who have a severe hypersensitivity to this medication. Xarelto also has warnings for individuals with certain medical conditions, such as hepatic impairment, prosthetic heart valves, and triple positive antiphospholipid syndrome.
What is Eliquis (apixaban)?
Eliquis (apixaban) is an anticoagulant (blood thinner) that works by stopping an enzyme complex called factor Xa. By stopping this enzyme complex from working, blood clots are less likely to form in your body so you're less likely to have a stroke or heart attack.
What are the risks and warnings for Eliquis (apixaban)?
Eliquis (apixaban) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options
What is the name of the drug that is used to treat strokes?
Eliquis (apixaban) and Xarelto (rivaroxaban) are both in a new group of anticoagulant drugs called novel oral anticoagulants (NOACs) used to prevent blood clots, stroke, and embolism, especially in people with atrial fibrillation. First approved by the FDA in 2011 and 2012, respectively, Eliquis and Xarelto quickly became two of the most popular blood thinners ...
How much does Eliquis cost?
Make sure your provider and pharmacist know all the medications you are taking. Prices for Eliquis (apixaban) start at just $ 493.19 with a GoodRx coupon.
What is Eliquis used for?
Eliquis is a medication that helps prevent blood clots, stroke, and embolism (when a blood clot blocks a blood vessel). It’s often compared to warfarin (Coumadin), but it has a couple advantages: It doesn’t require regular blood tests or major dietary changes, and it interacts with fewer drugs. Plus, researchers have found that Eliquis may ...
How long does it take to get off Eliquis?
If you are taking Eliquis (apixaban) because of joint replacement surgery, you'll most likely be taken off the medication after a few weeks. If you are taking Eliquis (apixaban) for atrial fibrillation or to treat blood clots, you'll most likely take it for a long time.
Can Eliquis be changed?
There are certain medications that can change the amount of Eliquis (apixaban) in your body. Some interactions can cause more bleeding and side effects, while others can stop Eliquis (apixaban) from working as well. Let your provider and pharmacist know about other prescription, over-the-counter medications, vitamins, and herbal supplements you're taking or have stopped recently.

Overview
Apixaban is used to prevent serious blood clots from forming due to a certain irregular heartbeat (atrial fibrillation) or after hip/knee replacement surgery.
May Treat: Deep venous thrombosis · Hip surgery deep vein thrombosis · Knee replacement deep vein thrombosis · Prevent thromboembolism in chronic atrial fibrillation · Venous thromboembolism recurrence and more
Drug Class: Direct Factor Xa Inhibitors
Availability: Prescription Required
Pregnancy: Consult a doctor before using
Lactation: This drug should not be given to breastfeeding mothers
May Treat: Deep venous thrombosis · Hip surgery deep vein thrombosis · Knee replacement deep vein thrombosis · Prevent thromboembolism in chronic atrial fibrillation · Venous thromboembolism recurrence and more
Drug Class: Direct Factor Xa Inhibitors
Availability: Prescription Required
Pregnancy: Consult a doctor before using
Lactation: This drug should not be given to breastfeeding mothers
Alcohol: Limit intake while taking this medication
Driving: May cause drowsiness or dizziness. Use caution
Manufacturer: BMS PRIMARYCARE
Medical uses
Side effects
Mechanism of action
History
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