Precautions
Generic Name: cefazolin (injection) (sef A zoe lin) Brand Name: Ancef, Kefzol. Medically reviewed by Drugs.com on Apr 19, 2019 – Written by Cerner Multum. Cefazolin is a cephalosporin (SEF a low spor in) antibiotic that is is used to treat bacterial infections, including severe or life-threatening forms.
What is the generic name for cefazolin injection?
Before using cefazolin, tell your doctor or pharmacist if you are allergic to it; or to other cephalosporins; or to penicillins; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
What should I know about cefazolin before using it?
Like those of several other cephalosporins, the chemical structure of cefazolin contains an N-methylthiodiazole (NMTD or 1-MTD) side-chain.
What is the chemical structure of cefazolin?
What class is cefazolin?
Cefazolin is used to treat bacterial infections in many different parts of the body. This medicine is also given before certain types of surgery to prevent infections. Cefazolin belongs to the class of medicines known as cephalosporin antibiotics. It works by killing bacteria or preventing their growth.
Is cephalexin and cefazolin the same?
Keflex (cephalexin) Ancef (cefazolin) is only available as an injectable, so it is usually only used in the hospital. It's good for treating many bacterial infections. Treats bacterial infections. Keflex (cephalexin) is good for treating many bacterial infections, and is available as a generic.
Is cefazolin the same as cefazolin?
Cefazolin, also known as cefazoline and cephazolin, is a first-generation cephalosporin antibiotic used for the treatment of a number of bacterial infections. Specifically it is used to treat cellulitis, urinary tract infections, pneumonia, endocarditis, joint infection, and biliary tract infections.
Is penicillin and cefazolin the same?
Penicillin VK (penicillin) is good at treating strep throat and is cheap, however, it can only be used for certain infections as many bacteria have developed resistance to it. Ancef (cefazolin) is available as a generic. It is good at treating many types of bacterial infections.
What is the brand name for cefazolin?
Cefazolin is available under the following different brand names: Kefzol and Ancef.
What is the generic name for ceftriaxone?
Ceftriaxone (Rocephin) is an antibiotic that treats many types of bacterial infections and prevents infections from surgery.
Is Rocephin and cefazolin the same?
Are Rocephin and Cefazolin the Same Thing? Rocephin (ceftriaxone sodium) and cefazolin are cephalosporin antibiotics used to treat many kinds of bacterial infections. Rocephin is also used to treat severe or life-threatening infections such as meningitis. Brand names for cefazolin include Kefzol and Ancef.
Is cefdinir the same as cefazolin?
Cefdinir was less potent than ceftriaxone, ceftazidime, and cefepime against Haemophilus influenzae, but was 2- to 8-fold more potent than cefoxitin and 8- to 32-fold more potent than cefazolin. Cefdinir was slightly less potent than ceftazidime, against beta-lactamase-positive Moraxella catarrhalis.
Is Keflex the same as cephalexin?
Cephalexin (Keflex) is a common antibiotic used to treat many types of bacterial infections. It doesn't have many side effects and is available as an affordable generic.
Is cefazolin and amoxicillin same?
The drugs belong to different classes. Cephalexin is a cephalosporin antibiotic and amoxicillin is a penicillin-type antibiotic. Brand names for cephalexin include Keflex and Daxbia. Brand names for amoxicillin include Amoxil, Moxatag, and Larotid.
Is cefazolin part of the penicillin family?
Since cefazolin has a unique side chain not shared by any other penicillin or cephalosporin, we can predict that approximately 1% of patients with a penicillin allergy will also experience hypersensitivity to cefazolin.
Can I give cefazolin if allergic to penicillin?
“Not only is cefazolin safe for nearly all patients with penicillin allergy, but also, studies have shown that it's well tolerated and has the appropriate spectrum of activity against organisms commonly encountered in surgical site infections.”
What Do I Need to Tell My Doctor Before I Take Cefazolin?
1. If you have an allergy to cefazolin or any other part of cefazolin. 2. If you are allergic to any drugs like this one, any other drugs, foods, o...
What Are Some Things I Need to Know Or Do While I Take Cefazolin?
1. Tell all of your health care providers that you take cefazolin. This includes your doctors, nurses, pharmacists, and dentists. 2. Very bad and s...
How Is This Medicine (Cefazolin) Best Taken?
Use cefazolin as ordered by your doctor. Read all information given to you. Follow all instructions closely. 1. It is given as a shot into a muscle...
What Are Some Side Effects That I Need to Call My Doctor About Right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor o...
What Are Some Other Side Effects of Cefazolin?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help i...
How Do I Store and/or Throw Out Cefazolin?
1. If you need to store cefazolin at home, talk with your doctor, nurse, or pharmacist about how to store it.
Is Ancef (cefazolin) a penicillin drug?
Ancef (cefazolin) is a cephalosporin, which is a class of antibiotics that are like cousins to penicillin. The molecule structures have some simila...
Is Rocephin and Ancef (cefazolin) the same?
Ceftriaxone (Rocephin) and Ancef (cefazolin) are not the same medication. Both are cephalosporin antibiotics, which means they have similar molecul...
Is Ancef (cefazolin) used to treat MRSA?
Ancef (cefazolin) will not treat infections that are due to MRSA, which is the abbreviation for methicillin-resistant Staph aureus. MRSA is conside...
How long does Ancef (cefazolin) stay in your system?
After you take a single dose of Ancef (cefazolin), if you have good kidney function, about 70% to 80% of the medication will be out of your body wi...
Is Ancef (cefazolin) a strong antibiotic?
Ancef (cefazolin) works against a good number of bacteria. There are other antibiotics that can treat more types of infections, or more serious inf...
What is Cefazolin used for?
This medication is known as a cephalosporin antibiotic. It works by stopping the growth of bacteria. Cefazolin is available under the following different brand names: Kefzol and Ancef. Dosages of Cefazolin: Dosage Forms and Strengths. Powder for injection.
Can Cefazolin be used during pregnancy?
Cefazolin may be acceptable for use during pregnancy.
Can you take cefazolin while pregnant?
Pregnancy and Lactation. Cefazolin may be acceptable for use during pregnancy. Either animal studies show no risk but human studies are not available or animal studies showed minor risks and human studies were done and showed no risk. Cefazolin is excreted in breast milk. Use with caution if breastfeeding.
Can you take Kefzol with Ancef?
This medication contains cefazolin. Do not take Kefzol or Ancef if you are allergic to cefazolin or any ingredients contained in this drug. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.
What is Cefazolin used for?
Cefazolin is a cephalosporin (SEF a low spor in) antibiotic that is used to treat bacterial infections , including severe or life-threatening forms. Cefazolin is also used to help prevent infection in people having certain types of surgery. Cefazolin may also be used for purposes not listed in this medication guide.
How to use cefazolin?
Use the medicine exactly as directed. Cefazolin is given as an infusion into a vein. A healthcare provider will give your first dose and may teach you how to properly use the medication by yourself. Cefazolin must be given slowly, and the infusion ...
What are the side effects of Cefazolin?
Common side effects may include: nausea, vomiting, diarrhea; rash; or. an allergic reaction. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Cefazolin side effects (more detail)
Can you take cefazolin if you are allergic to cephalosporin?
You should not take cefazolin if you are allergic to cefazolin or any other cephalosporin antibiotic ( cefdinir, cefalexin, Keflex, Omnicef, and others). an allergy to any type of penicillin. Tell your doctor if you are pregnant or breastfeeding. Do not give this medicine to a child without medical advice.
Does Cefazolin cause hives?
Cefazolin side effects. Get emergency medical help if you have signs of an allergic reaction ( hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).
Can Cefazolin be used for a viral infection?
Skipping doses can increase your risk of infection that is resistant to medication. Cefazolin will not treat a viral infection such as the flu or a common cold. This medicine can affect the results of certain medical tests.
Can you mix cefazolin with liquid?
Cefazolin may need to be mixed with a liquid (diluent) before using it. When using injections by yourself, be sure you understand how to properly mix and store the medicine. Prepare an injection only when you are ready to give it. Do not use if the medicine has changed colors or has particles in it.
How much does Cefazolin cost?
Prices for Ancef (cefazolin) start at just $ 23.39 with a GoodRx coupon. They’re fast, easy-to-use and free!
How long does it take for Cefazolin to get out of your system?
After you take a single dose of Ancef (cefazolin), if you have good kidney function, about 70% to 80% of the medication will be out of your body within 24 hours. Keep in mind that most people take Ancef (cefazolin) many times a day, so it will stay in your system longer if you have taken multiple doses in a row.
What is ancef in Medicare?
Medicare. Ancef (cefazolin) is a cephalosporin antibiotic that treats many types of bacterial infections and prevents infections from surgery. It's only available in injection form, so it's usually given in the hospital or provider's office.
What is ancef a class of antibiotics?
Ancef (cefazolin) is a cephalosporin, which is a class of antibiotics that are like cousins to penicillin. The molecule structures have some similarities, and they both kill bacteria by preventing them from making their own protective covering.
What are the risk factors for allergic reactions to cephalosporin?
If you've had an allergic reaction from taking penicillin-type or cephalosporin antibiotics, such as trouble breathing, or swelling in your face and neck , let your provider know before taking this.
Can you take Cefazolin for a bacterial infection?
Risk factors: Taking Ancef (cefazolin) for a non-bacterial infection. You should only take Ancef (cefazolin) for bacterial infections. Using Ancef (cefazolin) or other antibiotics when they are not necessary can lead to drug-resistant bacteria, which are much harder to treat.
Is Cefazolin a stronger antibiotic?
Ancef (cefazolin) works against a good number of bacteria. There are other antibiotics that can treat more types of infections, or more serious infections. "Stronger" antibiotics are not always the best choice, though. Your provider will choose the antibiotic that is best for you.
What is cefazolin used for?
It is indicated for use in the following infections: Respiratory tract infections. Urinary tract infections. Skin infections. Biliary tract infections. Bone and joint infections.
When was cefazolin first used?
Cefazolin was patented in 1967 and came into commercial use in 1971. It is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system. It is available as a generic medication.
What are the symptoms of penicillin allergy?
Common (1-10%): diarrhea, stomach pain or upset stomach, vomiting, and rash. Uncommon (<1%): dizziness, headache, fatigue, itching, transient hepatitis. Patients with penicillin allergies could experience a potential reaction to cefazolin and other cephalosporins.
How does cefazolin inhibit cell wall biosynthesis?
Cefazolin inhibits cell wall biosynthesis by binding penicillin-binding proteins which stops peptidoglycan synthesis. Penicillin-binding proteins are bacterial proteins that help to catalyze the last stages of peptidoglycan synthesis, which is needed to maintain the cell wall. They remove the D- alanine from the precursor of the peptidoglycan. The lack of synthesis causes the bacteria to lyse because they also continually break down their cell walls. Cefazolin is bactericidal, meaning it kills the bacteria rather than inhibiting their growth.
What temperature does cefazolin decompose?
198 to 200 °C (388 to 392 °F) (decompose.) Cefazolin, also known as cefazoline and cephazolin, is an antibiotic used for the treatment of a number of bacterial infections. Specifically it is used to treat cellulitis, urinary tract infections, pneumonia, endocarditis, joint infection, and biliary tract infections.
Can hemodialysis cause cefazolin to be taken with other antibiotics?
Cefazolin levels are not significantly affected by liver disease. As with other antibiotics, cefazolin may interact with other medications being taken.
Can you give cefazolin to a GBS patient?
Although penicillin and ampicillin are the standard of care for GBS prophylaxis, penicillin-allergic women with no history of anaphylaxis can be given cefazolin instead. These patients should be closely monitored as there is a small chance of an allergic reaction due to the similar structure of the antibiotics.
What is cefazolin used for?
Uses. Cefazolin is an antibiotic used to treat a wide variety of bacterial infections. It may also be used before and during certain surgeries to help prevent infection. This medication is known as a cephalosporin antibiotic. It works by stopping the growth of bacteria.
How to report cefazolin side effects?
You may report side effects to Health Canada at 1-866-234-2345. Before using cefazolin, tell your doctor or pharmacist if you are allergic to it; or to other cephalosporins; or to penicillins;
Can cefazolin cause allergic reactions?
Before using cefazolin, tell your doctor or pharmacist if you are allergic to it; or to other cephalosporins; or to penicillins; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Can Cefazolin cause colitis?
Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, stomach /intestinal diseases (e.g., colitis ). Cefazolin may cause live bacterial vaccines (such as typhoid vaccine) to not work as well.
What is the action of cephalosporin?
In vitro tests demonstrate that the bactericidal action of cephalosporin results from the inhibition of cell wall synthesis. By binding to specific penicillin-binding proteins (PBP) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis.
Does cefazolin affect the fetus?
When cefazolin sodium injection has been used prior to cesarean section, drug levels in cord blood have been approximately one-fourth to one-third of maternal drug levels. The medication appears to have no adverse effects on the fetus.
Is cefazolin a first generation cephalosporin?
Cefazolin is a semisynthetic first-generation cephalosporin for parenteral administration. Cefazolin has broad-spectrum action due to the inhibition of bacterial cell wall synthesis. It attains high serum levels and its excreted quickly via the urine.
