How likely is CIN to go away?
Approximately 90 percent of these lesions will either regress to negative or remain CIN 1, saving these patients from a potentially morbid procedure. Follow-up for these patients is with HPV testing in one year (algorithm 3).
Can you get CIN without HPV?
HPV infection is necessary but not sufficient to develop CIN. More than 90% of infections are spontaneously cleared by the immune system within one year without treatment. Approximately 60% of CIN 1 lesions regress without treatment and less than 1% progress to cancer.
How long does it take to get HPV from CIN?
The estimated interval between the recorded onset of persistent HR-HPV infection and the development of CIN was 4–70 months (Table 1). Categorical analysis was carried out which included single HR-HPV infection, co-infection, and the most prevalent HR-HPV types.
Does CIN go away on its own?
Often, with mild dysplasia (CIN I), no treatment is needed. In most cases, mild dysplasia resolves on its own and doesn't become cancerous. Your doctor may recommend follow-up in a year to check for additional changes.
Is CIN a precancer?
CIN 1 is not cancer and usually goes away on its own without treatment, but sometimes it can become cancer and spread into nearby tissue. CIN 1 is sometimes called low-grade or mild dysplasia. Also called cervical squamous intraepithelial neoplasia 1.
What is the most common cause of CIN?
Cervical intraepithelial neoplasia is usually caused by certain types of human papillomavirus (HPV) and is found when a cervical biopsy is done. Cervical intraepithelial neoplasia is not cancer, but may become cancer and spread to nearby normal tissue.
Will removing the cervix cure HPV?
Unfortunately, once you have been infected with HPV, there is no treatment that can cure it or eliminate the virus from your system. A hysterectomy removes the cervix, which means that the risk of developing cervical cancer because of persistent HPV infection will essentially be eliminated.
How long does it take CIN 1 to go away?
CIN-1 is due to infection with HPV (human papilloma virus). Of every 10 cases of HPV infection, eight will go away without treatment within 12 months.
How quickly can CIN1 progress?
cervical intraepithelial neoplasia-1 (CIN1) has high rates of spontaneous regression (60% to 80%) within 2 to 5 years, whereas progression to a high-grade cervical lesion is relatively low (∼12%), and it seldom progresses to invasive cancer.
How do I stop CIN?
On Windows you'd use Ctrl-Z, on UNIXes you'd use Ctrl-D. Save this answer.
Why is my body not clearing HPV?
Summary: The body's ability to clear an infection by the cancer-causing human papilloma virus (HPV) may be largely due to unpredictable division patterns in HPV-infected stem cells, rather than the strength of the person's immune response as previously thought.
What is a major risk factor for CIN?
Human papillomavirus (HPV) infection Infection by the human papillomavirus (HPV) is the most important risk factor for cervical cancer. HPV is a group of more than 150 related viruses. Some of them cause a type of growth called papillomas, which are more commonly known as warts.
Can you have abnormal cervical cells without HPV?
Your doctor may use other words to describe this result, like equivocal, inconclusive, or ASC-US. These all mean the same thing—that your cervical cells look like they could be abnormal. It is not clear if it's related to HPV. It could be related to life changes like pregnancy, menopause, or an infection.
Can you have CIN 3 without HPV?
These findings suggest that some cases of CIN 3 were based on histologic overcall. In reviewing cases of CIN 3 in the 33 women who tested negative for high-risk HPV DNA, investigators found only 8 cases attributable to falsely-negative HPV testing, whereas 12 were related to incident HPV infection.
Is CIN caused by HPV?
CIN is usually caused by certain types of human papillomavirus (HPV) and is found when a cervical biopsy is done. CIN is not cancer, but may become cancer and spread to nearby normal tissue.
What causes cervical dysplasia besides HPV?
If your immune system does not clear the virus it can eventually lead to the development of cervical dysplasia. Risk factors for cervical dysplasia are the same for cervical cancer. Besides HPV, they are sexual history, history of other STIs, smoking, and weakened immune system.
Cervical Intraepithelial Neoplasia (CIN) Symptoms
Causes
- Cervical intraepithelial neoplasia is most commonly caused by variations of HPV (i.e., HPV16 and HPV18) infecting a woman’s reproductive tract. The World Health Organization says these two HPV types (16 and 18) cause 70% of cervical cancers and precancerous cervical lesions.4 Some risk factors also increase your likelihood of coming into contact with HPV, but you should know it…
Diagnosis
- If your pap smear results show abnormal cells, your doctor or doctor’s office will contact you to discuss next steps. While this is an understandably upsetting experience, precancerous cells don’t typically become cancerous for years, if at all.4 The next step is often to get an actual look at what’s happening via colposcopy so your doctor can examine the cervix area under a microscop…
Treatment
- Treatment may not be necessary in cases of low-grade CIN 1 because the underlying infection often resolves on its own. For higher-grade disease, the cells may need to be destroyed or removed to keep them from multiplying or mutating years from now. If you have a more severe grade of CIN (2 or 3), treatment options include:6 1. Cone biopsyto remove abnormal tissues; us…
Prognosis
- The prognosis of CIN will depend upon two factors: 1. The level of severity of abnormal cell coverageon your cervix upon discovery from pap smear. This is why detecting these cells as early as possible is best (the cells have less opportunity to multiply or mutate). 2. Your ability and willingness to follow the ASCCP recommendations
A Word from Verywell
- It can be scary when you get a pap smear back with abnormal results, but most of the time there is nothing to worry about. Especially when discovered early on, the risk of these cells developing into cancer is fairly low. Still, leaving something like this untreated is not recommended. You can protect yourself by making pap smears part of your healthcare routine and by following through …