Precautions
Clindamycin has replaced amoxicillin as the recommended antibiotic for the management of odontogenic infections. Occasionally, it is indicated to treat penicillin-resistant bacteria. Moreover, it may help with sinusitis, however, there are other more frequently used antibiotics for it. On the other hand, amoxicillin is used for strep throat.
Is clindamycin like amoxcillin?
No, clindamycin is not a penicillin antibiotic. Instead, it belongs to a class of medications known as lincomycin antibiotics, or lincosamides. Clindamycin is a broad-spectrum antibiotic, with the ability to impact many types of bacteria in the body. Continue reading
Is clindamycin a penicillin based antibiotic?
Zithromax Z-PAK ( azithromycin) and Cipro ( ciprofloxacin) are antibiotics used to treat susceptible bacterial infections. Zithromax and Cipro belong to different antibiotic classes. Zithromax is a macrolide antibiotic and Cipro is a quinolone antibiotic.
Is Zithromax a quinolone?
Clindamycin is an antibiotic that may be used to treat a wide range of infections including those involving gram-positive and anaerobic bacteria (anaerobic means living without air). Clindamycin works by inhibiting bacterial protein synthesis, which inhibits bacterial growth.
Why is clindamycin used to treat a gum infection?
What is clindamycin used for?
What subunit of the ribosome is clindamycin?
What antibiotics are used for babesiosis?
Is clindamycin erythromycin resistant?
Is clindamycin the same as macrolide?
Can clindamycin cause esophagitis?
Is clindamycin contraindicated?
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About this website
Which antibiotics are fluoroquinolones?
FDA-approved fluoroquinolones include levofloxacin (Levaquin), ciprofloxacin (Cipro), ciprofloxacin extended-release tablets, moxifloxacin (Avelox), ofloxacin, gemifloxacin (Factive) and delafloxacin (Baxdela). There are more than 60 generic versions.
Is clindamycin fluoroquinolone an antibiotic?
Cleocin (clindamycin hydrochloride) and Cipro (ciprofloxacin) are antibiotics used to treat infections caused by bacteria. Cleocin and Cipro belong to different antibiotic drug classes. Cleocin is a lincomycin antibiotic and Cipro is a quinolone antibiotic.
What class of drugs is clindamycin in?
Clindamycin is in a class of medications called lincomycin antibiotics. It works by slowing or stopping the growth of bacteria. Antibiotics such as clindamycin will not work for colds, flu, or other viral infections.
What drugs are in the clindamycin family?
Clindamycin and lincomycin are the only members of the lincosamide family. Lincomycin is only available as an injectable solution, and doctors prescribe it for serious infections.
Can I take clindamycin if allergic to Cipro?
Interactions between your drugs No interactions were found between Cipro and clindamycin. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
What is the major side effect of clindamycin?
Serious skin reactions can occur with this medicine. Check with your doctor right away if you have blistering, peeling, or loose skin, red skin lesions, severe acne or skin rash, sores or ulcers on the skin, or fever or chills while you or your child are using this medicine.
What can you not mix with clindamycin?
Most frequently checked interactionsAspirin Low Strength (aspirin)Benadryl (diphenhydramine)Claritin (loratadine)Cymbalta (duloxetine)Fish Oil (omega-3 polyunsaturated fatty acids)Flexeril (cyclobenzaprine)Flonase (fluticasone nasal)Lyrica (pregabalin)More items...
What is a substitute for clindamycin?
Alternatives to a clindamycin allergy include synercid, linezolid, metronidazole, imipenem, vancomycin, bactrim, and doxycycline.
What is another name for clindamycin?
Clindamycin is available in several brand-name forms: Cleocin, Cleocin T, Evoclin, and Clindesse.
Is clindamycin a strong antibiotic?
Clindamycin is a strong broad-spectrum antibiotic, typically prescribed for serious infections, such as life-threatening methicillin-resistant Staphylococcus aureus (MRSA) skin infections.
Can clindamycin cause joint inflammation?
In spite of the expanded use of clindamycin in bone infections, the adverse reactions of this antibiotic are minor. Polyarthritis is the only joint adverse reaction that has been reported rarely and the monoarthritis has not been reported in articles.
Why can't you lay down after taking clindamycin?
You should avoid lying down after taking the antibiotic clindamycin because it may slow the time it takes for the medication to move down your esophagus into your stomach, potentially causing irritation your esophagus.
Is clindamycin a strong antibiotic?
Clindamycin is a strong broad-spectrum antibiotic, typically prescribed for serious infections, such as life-threatening methicillin-resistant Staphylococcus aureus (MRSA) skin infections.
What foods should you avoid when taking clindamycin?
Avoid spicy or rich foods that may irritate your stomach. Taking a probiotic, which may help to replenish beneficial bacteria in your gut, may also minimize side effects.
What kind of infections does clindamycin treat?
Clindamycin is a medication used for the treatment of numerous infections, including but not limited to septicemia, intra-abdominal infections, lower respiratory infections, gynecological infections, bone and joint infections, and skin and skin structure infections.
Is clindamycin better than amoxicillin?
Amoxicillin may be safer than clindamycin as endocarditis prophylaxis. Amoxicillin may be safer than clindamycin as endocarditis prophylaxis before dental work, a new study from England suggests. Dentists have historically given antibiotic prophylaxis (AP) to patients at risk of infective endocarditis.
What are the best antibiotics for a tooth infection?
There are several antibiotics that kill the common mouth bacteria that cause tooth infections. The best (first-line) antibiotics for tooth infectio...
What is the best antibiotic to treat strep throat?
Penicillin or amoxicillin are considered the best first-line treatments for Strep throat. According to the CDC (Centers for Disease Control and Pre...
Is clindamycin a strong antibiotic?
Clindamycin is a strong broad-spectrum antibiotic, typically prescribed for serious infections, such as life-threatening methicillin-resistant Stap...
Can I take clindamycin if I am allergic to penicillin?
Yes, you can. It is recommended that the use of the antibiotic clindamycin be reserved for patients who are allergic to penicillin or for those pat...
Is clindamycin a penicillin?
No, clindamycin is not a penicillin antibiotic. Instead, it belongs to a class of medications known as lincomycin antibiotics, or lincosamides. Cli...
CONTRAINDICATIONS, WARNINGS and ADVERSE REACTIONS). - DailyMed
breast-fed infant for possible adverse effects on the gastrointestinal flora, such as diarrhea, candidiasis (thrush, diaper rash) or rarely, blood in the stool indicating possible
National Center for Biotechnology Information
National Center for Biotechnology Information
Clindamycin Uses, Dosage & Side Effects - Drugs.com
Generic name: clindamycin (oral/injection) [ klin-da-MYE-sin ] Brand names: Cleocin HCl, Cleocin Pediatric, Cleocin Phosphate, Cleocin Phosphate ADD-Vantage, Clindesse, ClindaMax Vaginal Drug class: Lincomycin derivatives Medically reviewed by Kaci Durbin, MD.Last updated on Jul 22, 2022. Warnings; Side effects; Interactions; Dosage; FAQ; What is clindamycin?
Clindamycin - Antimicrobe
Clindamycin Antibiotic Class: Lincosamide Antimicrobial Spectrum: Streptococcus spp., Staphylococcus spp., H. influenzae, M. catarrhalis, Bacteroides spp.,
UpToDate
This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options.
UpToDate
This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options.
How to take clindamycin?
Clindamycin oral is taken by mouth. Clindamycin injection is injected into a muscle, or as an infusion into a vein. A healthcare provider will give your first dose and may teach you how to properly use the medication by yourself. Take the capsule with a full glass of water to keep it from irritating your throat.
What are the side effects of clindamycin?
a metallic taste in your mouth (after clindamycin injection). Common clindamycin side effects may include: nausea, vomiting, stomach pain; mild skin rash; or. vaginal itching or dis charge; This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
What is the best antibiotic for tooth infection?
The best (first-line) antibiotics for tooth infection include: Amoxicillin, Penicillin, Cephalexin, Clindamycin, Azithromycin. Amoxicillin is often the first choice because it is widely effective and has the fewest gastrointestinal side effects. Continue reading.
What happens if you are allergic to clindamycin?
Get emergency medical help if you have any signs of an allergic reaction to clindamycin: (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).
Can you take clindamycin if you are allergic to lincomycin?
Before taking this medicine. You should not use this medicine if you are allergic to clindamycin or lincomycin. To make sure clindamycin is safe for you, tell your doctor if you have ever had: colitis, Crohn's disease, or other intestinal disorder; eczema, or allergic skin reaction; liver disease;
Can you take clindamycin if you have kidney disease?
Before using clindamycin, tell your doctor if you have kidney disease, liver disease, an intestinal disorder such as colitis or Crohn's disease, or a history of asthma, eczema, or allergic skin reaction. Take clindamycin for the full prescribed length of time.
Can you take clindamycin for a viral infection?
Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Clindamycin will not treat a viral infection such as the common cold or flu.
When was Ciprofloxacin first used?
Ciprofloxacin has been used in the United States since 1988 , but it was not until 2001 that a clinical case-control study showed the association between fluoroquinolone use and risk of CDAD [ 6 ].
Does gatifloxacin affect fecal flora?
The authors speculate that the enhanced anaerobic spectrum of newer fluoroquinolones, such as gati floxacin, may have a more disruptive effect on the fecal flora [ 5 ]. Ironically, these agents are usually much more active against C. difficile than are older fluoroquinolones, such as ciprofloxacin [ 11 ].
Does gatifloxacin reduce CDAD?
Foremost is the fact that it demonstrates a difference in CDAD risk during periods when 2 different but very similar fluoroquinolones (levofloxacin and gatifloxacin) were in use, and it demonstrates that the high risk of CDAD observed with gatifloxacin can be reduced by removing the drug from use and replacing it with a similar agent from the same class. Gaynes et al. [ 5] were particularly successful in implementing the process of changing from one fluoroquinolone to the other, achieving 98%–99% compliance. However, the most important finding of Gaynes et al. [ 5] is that, after institution of the antimicrobial use change, there followed a significant reduction in CDAD rates [ 5 ]. However, CDAD rates after use of each of the fluoroquinolones were extraordinarily high (34% for gatifloxacin and 17% for levofloxacin). Furthermore, the attributable risk associated with gatifloxacin use was very high: 14 [67%] of 21 patients who had CDAD received gatifloxacin, compared with 5 (24%) of 21 patients who received clindamycin, the second-most frequently associated antimicrobial. In addition, risk of CDAD in the long-term care facility increased with the duration of gatifloxacin therapy. Rates of CDAD per 1000 patient-days were 3–4 times higher in the long-term care facility and in the acute care hospital during the period of gatifloxacin use (as well as the first period of levofloxacin use in the hospital), compared with 10-year historical CDAD rates for the acute care section of another Veterans Affairs hospital for the period of 1982–1991, before most fluoroquinolones were available [ 10 ].
Does clindamycin decrease CDAD?
The good news has been that CDAD rates have markedly decreased when the use of clindamycin or third-generation cephalosporins has been reduced in hospitals where these agents were associated with high CDAD rates [ 3, 4 ].
Can C difficile be resistant to fluoroquinolones?
I predict that, when this is done, it will be confirmed that clones of C. difficile that are resistant to fluoroquinolones are responsible for an increasing number of CDAD outbreaks associated with the widespread hospital use of newer fluoroquinolones.
How do fluoroquinolones differ from quinolones?
Quinolones and fluoroquinolones also differ in the way they are absorbed, metabolized and excreted in the body.
What is the purpose of fluoroquinolones?
Quinolones and fluoroquinolones may also be used to treat unusual infections such as anthrax or plague. Doctors may also decide to use them for other types of infection when other alternative treatment options have failed or cannot be used.
What are Quinolones?
Quinolones are a type of antibiotic. Antibiotics kill or inhibit the growth of bacteria.
What are quinolones and fluoroquinolones used for?
Quinolones and fluoroquinolones are considered broad-spectrum antibiotics. This means that they are effective against a wide range of bacteria.
What are the side effects of quinolones and fluoroquinolones?
The most commonly reported side effects include diarrhea, nausea, abnormal liver function tests, vomiting, and rash.
What are the effects of quinolones on DNA?
Quinolones and fluoroquinolones detrimentally affect the function of two enzymes produced by bacteria, topoisomerase IV and DNA gyrase, so that they can no longer repair DNA or help in its manufacture.
Which enzyme is more active against gram positive bacteria?
Those that are more active against topoisomerase IV have more of an effect against gram-positive bacteria, those that are active against DNA gyrase, are more active against gram-negative bacteria. Newer fluoroquinolones tend to target these enzymes equally. Quinolones and fluoroquinolones also differ in the way they are absorbed, ...
What is fluoroquinolone antibiotic?
Fluoroquinolone antibiotics. The fluoroquinolones are a family of synthetic broad-spectrum antibiotics, which eradicate bacteria by interfering with DNA replication. However, the fluoroquinolones are relatively ineffective against intracellular pathogens. Fluoroquinolones can be used as an acute-phase antibiotic for patients on ...
Why are fluoroquinolones used as an acute-phase antibiotic?
Fluoroquinolones can be used as an acute-phase antibiotic for patients on the Marshall Protocol because they produce little or no immunopathology.
What is the association between oral fluoroquinolones and retinal detachment?
Association between oral fluoroquinolone use and the development of retinal detachment: a systematic review and meta-analysis of observational studies. A systematic review and meta-analysis of the association between systemic fluoroquinolones and retinal detachment.
Why are fluoroquinolones used in hospitals?
Fluoroquinolones are used by hospitals as “first-line” antibiotics. If a patient becomes sick with an opportunistic infection, it is not good to have encouraged the persistent bacteria to have developed a resistance to fluoroquinolones (potentially due to previous over-use of the drugs)
Can antibiotics cause withdrawal symptoms?
Antibiotics for some reason, sometimes seem to aggravate withdrawal symptoms. However, one class of antibiotics, the quinolones, actually displace benzodiazepines from their binding sites on GABA-receptors. These can precipitate acute withdrawal in people taking or tapering from benzodiazepines.
Do fluoroquinolones act in the same way?
All the fluoroquinolones are thought to act in a similar way.
Can Ceftin be used for eye infections?
Even though the risk of eye damage is still low, it seems that it might be prudent for physicians to try Ceftin for acute infections, before resorting to the flouroquinolones .
What is clindamycin used for?
Clindamycin can be used for infections (eg, skin and soft-tissue infections) in communities where community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) is common; whether clindamycin is useful depends on local resistance patterns. Clindamycin can be used for infections due to clindamycin - and erythromycin -susceptible strains.
What subunit of the ribosome is clindamycin?
Click here for Patient Education. Clindamycin is a lincosamide antibiotic that is primarily bacteriostatic. It binds to the 50S subunit of the ribosome, thus inhibiting bacterial protein synthesis.
What antibiotics are used for babesiosis?
With penicillin for infections caused by toxigenic streptococci (because clindamycin decreases the bacteria’s toxin production) With pyrimethamine for cerebral toxoplasmosis. With quinine for babesiosis or falciparum malaria. With primaquine for Pneumocystis jirovecii pneumonia.
Is clindamycin erythromycin resistant?
Clindamycin can be used for infections due to clindamycin - and erythromycin -susceptible strains. However, some CA-MRSA strains are clindamycin - susceptible and erythromycin -resistant; erythromycin resistance in these strains may be due to an active efflux mechanism or modification of the ribosomal target.
Is clindamycin the same as macrolide?
Indications for Clindamycin. The spectrum of activity for clindamycin is similar to that of the macrolide erythromycin (see table Some Clinical Uses of Macrolides ) except that clindamycin is. Effective for infections due to anaerobes (particularly Bacteroides species, including Bacteroides fragilis ), community-acquired methicillin-resistant ...
Can clindamycin cause esophagitis?
Hypersensitivity reactions may occur. If not swallowed with water, clindamycin may cause esophagitis.
Is clindamycin contraindicated?
Clindamycin is contraindicated in patients who have had an allergic reaction to it, and it should be used with caution in those who have a history of regional enteritis, ulcerative colitis, or antibiotic-associated colitis.
