is esomeprazole dangerous

Precautions

Along with its needed effects, esomeprazole may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking esomeprazole:

Are there any side effects of esomeprazole?

For people with severe liver problems: The maximum dosage of esomeprazole magnesium shouldn’t be more than 20 mg per day. Take this drug as directed by your doctor. Your doctor should give you the drug at the lowest dosage possible and for the shortest time needed. This will lower your risk of side effects.

How much esomeprazole can you take with liver problems?

Esomeprazole magnesium belongs to a class of drugs called proton pump inhibitors. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions. Esomeprazole decreases the amount of acid your stomach produces. It works by blocking the proton pump in the stomach’s cells.

What class of drug is esomeprazole?

Esomeprazole effectively heals inflamed tissue in the gastrointestinal tract and relieves symptoms of heartburn. Esomeprazole is usually only taken short-term, as long-term use of proton pump inhibitors (such as esomeprazole) has been associated with a higher risk of fractures, kidney conditions, magnesium, and vitamin B12 deficiency. 5.

How effective is esomeprazole for heartburn?

How does esomeprazole work?

What is esomeprazole magnesium used for?

Can esomeprazole be taken with other medications?

Does esomeprazole cause drowsiness?

Is esomeprazole a prescription drug?

How to avoid interactions with medications?

What to do if you have serious side effects?

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Is it OK to take esomeprazole every day?

Sometimes your doctor may advise you to take it for longer, even many years. Your doctor may suggest taking esomeprazole only when you have symptoms. This means you will not have to take it every day. Once you feel better, you can stop taking it, often after a few days or weeks.

Who should not use esomeprazole?

This medicine may increase your risk of having fractures of the hip, wrist, and spine. This is more likely if you are 50 years of age and older, use high doses, or use it for one year or more.

How long can esomeprazole be taken?

Do not take nonprescription esomeprazole for longer than 14 days or treat yourself with esomeprazole more often than once every 4 months without talking to your doctor. Continue to take prescription esomeprazole, even if you feel well. Call your doctor if your symptoms worsen or do not improve during this time.

What are the long term side effects of esomeprazole?

Long term side effects Taking esomeprazole for more than a year may increase your chances of certain side effects, including: bone fractures. gut infections. vitamin B12 deficiency – symptoms include feeling very tired, a sore and red tongue, mouth ulcers and pins and needles.

How do I come off esomeprazole?

Lower your PPI dose for 2-4 weeks day for 1-2 weeks, and then take one pill every other day for another 1-2 weeks. If tapering off over 2-4 weeks feels too fast, you may taper more gradually. It is okay to follow this plan for 8- 12 weeks.

What can you not take with esomeprazole?

DRUG INTERACTIONS Esomeprazole (Nexium) can interact with many drugs, vitamins and herbal supplements. Common medications that should not be taken at the same time as esomeprazole (Nexium) include clopidogrel (Plavix), St. John's Wort, rifampin (Rifadin), and methotrexate.

Can esomeprazole heal the esophagus?

Five out of 8 studies showed that esomeprazole 40 mg od achieves better healing rates of erosive esophagitis after 4 and 8 weeks of treatment compared with omeprazole 20 mg, lansoprazole 30 mg, or pantoprazole 40 mg od (Table 1). In these trials a total of 13,797 patients with erosive GERD were included.

Should esomeprazole be taken on an empty stomach?

Take this medicine at least 1 hour before a meal and for the full time of treatment, even if you begin to feel better after a few days. If you are taking this medicine to treat an ulcer caused by an H. pylori infection, take it together with the antibiotics (eg, amoxicillin, clarithromycin) at the same time of day.

Can esomeprazole cause weight gain?

Yes, Nexium and other heartburn drugs may cause weight gain — as can other drugs, such as certain antidepressants, beta-blockers, and antihistamines.

What is the safest antacid to take long term?

Proton pump inhibitors are accepted as the most effective initial and maintenance treatment for GERD. Oral pantoprazole is a safe, well tolerated and effective initial and maintenance treatment for patients with nonerosive GERD or erosive esophagitis.

How good is esomeprazole?

Esomeprazole has an average rating of 5.8 out of 10 from a total of 247 ratings on Drugs.com. 49% of reviewers reported a positive experience, while 38% reported a negative experience.

Does esomeprazole affect sleep?

After the second week of treatment, esomeprazole significantly decreased the wake time (from 47.5±39.6 min to 36.0±27.1 min) and sleep latency period (from 19.5±19.8 min to 9.9±10.2 min) and increased the percentage of sleep time (from 89.1±8.8% to 91.9±6.3%); however, improvements were not noted in all objective ...

Does esomeprazole interact with other medications?

Additional examples of drugs that may interact with esomeprazole include: Anticoagulants such as cilostazol, methotrexate, digoxin, tacrolimus and saquinavir. When these drugs are taken simultaneously with esomeprazole, their risk of side effects may increase.

Is esomeprazole good for gastritis?

Nexium and other PPIs are commonly used off-label, meaning they are used to treat other conditions not specified by the FDA. Off-label uses of esomeprazole include: Peptic ulcer disease (by any cause)3. Chronic gastritis (by any cause)4.

Can you take Nexium with high blood pressure?

It depends on the medication you are taking to treat high blood pressure and cholesterol. For example, taking a diuretic can be impacted if you also take Nexium. I recommend discussing with your physician or pharmacist to make sure there are no drug interactions of concern if you combine the medications.

Why should you not take Nexium?

Nexium increases the risk of developing cutaneous lupus erythematosus (CLE) and systemic lupus erythematosus (SLE). People with either disease may see their condition worsen if they take Nexium. The drug also increases the likelihood of developing bone fractures.

Esomeprazole: 7 things you should know - Drugs.com

Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex (updated 12 Oct 2022), Cerner Multum™ (updated 21 Sep 2022), ASHP (updated 12 Oct 2022 ...

Esomeprazole Side Effects: Common, Severe, Long Term - Drugs.com

Esomeprazole Side Effects. Medically reviewed by Drugs.com. Last updated on Aug 21, 2022. Consumer; Professional; FAQ; For the Consumer. Applies to esomeprazole: oral capsule delayed release, oral packet, oral tablet delayed release. Other dosage forms: oral capsule delayed release

Esomeprazole Magnesium - Uses, Side Effects, and More - WebMD

Find patient medical information for esomeprazole magnesium oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.

Side effects of esomeprazole - NHS

Long term side effects. If you take esomeprazole for more than 3 months, the levels of magnesium in your blood may fall. Low magnesium can make you feel tired, confused, dizzy and cause muscle twitches, shakiness and an irregular heartbeat.

Esomeprazole Magnesium Side Effects Center - RxList

What Is Esomeprazole Magnesium? Esomeprazole Magnesium delayed-release capsules are a proton pump inhibitor indicated for treatment of gastroesophageal reflux disease (), risk reduction of nonsteroidal anti-inflammatory drug ()-associated gastric ulcer, and pathological hypersecretory conditions, including Zollinger-Ellison Syndrome. ...

What should I avoid while taking esomeprazole?

If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine.

What other drugs will affect esomeprazole?

Tell your doctor about all your current medicines. Many drugs can affect esomeprazole, especially:

How should I take esomeprazole?

Use exactly as directed on the label, or as prescribed by your doctor.

Why is esomeprazole given?

Esomeprazole may also be given to prevent gastric ulcer caused by infection with Helicobacter pylori (H. pylori), or by the use of nonsteroidal anti-inflammatory drugs ( NSAIDs ).

How to give esomeprazole capsules?

The esomeprazole capsule can be given through a nasogastric (NG) feeding tube. Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

How long does esomeprazole last?

Esomeprazole is usually given for 4 to 8 weeks only. Your doctor may recommend a second course of treatment if you need additional healing time. Use esomeprazole for the full prescribed length of time, even if your symptoms quickly improve.

Can you take esomeprazole for a second time?

Your doctor may recommend a second course of treatment if you need additional healing time. Use esomeprazole for the full prescribed length of time, even if your symptoms quickly improve. Call your doctor if your symptoms do not improve or if they get worse while you are taking this medicine.

What are the side effects of esomeprazole?

Check with your doctor immediately if any of the following side effects occur while taking esomeprazole: Incidence not known. Blistering, peeling, or loosening of the skin. bloating. chills. constipation. cough. darkened urine. difficulty with swallowing.

What are the side effects of triple therapy?

The most frequently reported adverse reactions for patients who received triple therapy for 10 days were diarrhea, taste perversion, and abdominal pain. [ Ref]

Does esomeprazole need medical attention?

Side effects not requiring immediate medical attention. Some side effects of esomeprazole may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine.

What class is esomeprazole?

Esomeprazole belongs to the class of medicines known as proton pump inhibitors (PPIs).

What is esomeprazole used for?

Esomeprazole is an acid-suppressing agent that may be used to treat conditions associated with excessive stomach acid production, such as gastroesophageal reflux (GERD) and stomach ulcers.

How long does it take for esomeprazole to work?

Usually, only up to 8 weeks of treatment is recommended. Controlled studies have not investigated use beyond 6 months; however, esomeprazole has been used long-term for the treatment of hypersecretory conditions such as Zollinger-Ellison syndrome.

What medications interact with esomeprazole?

Common medications that may interact with esomeprazole include: antibiotics, such as cefuroxime. antidepressants, such as citalopram, clomipramine, escitalopram, imipramine, St John's wort, or trimipramine. antifungals, such as fluconazole, itraconazole, ketoconazole, or voriconazole.

Is esomeprazole good for kidney disease?

Useful in the treatment of hypersecretory conditions such as Zollinger-Ellison syndrome. The dosage of esomeprazole does not need adjusting in people with kidney disease. Available IV which may be a good short-term alternative to oral treatment in people with erosive esophagitis who are unable to take the drug orally.

Does esomeprazole reduce stomach acid?

Esomeprazole reduces the production of stomach acid by irreversibly blocking the actions of an enzyme responsible for acid production, called H+/K+ ATPase (also known as the gastric proton pump). The proton pump is located in the parietal cells of the stomach wall.

Is esomeprazole a bioequivalent?

Esomeprazole delayed-release capsules and esomeprazole for delayed-release oral suspension are bioequivalent (the same dosage has the same effect in the body).

What is esomeprazole?

Esomeprazole injection is used to treat symptoms of gastroesophageal reflux disease ( GERD) and other conditions involving excessive stomach acid such as Zollinger-Ellison syndrome . Esomeprazole is also used to promote healing of erosive esophagitis (damage to your esophagus caused by stomach acid).

What other drugs will affect esomeprazole?

Tell your doctor about all your current medicines. Many drugs can affect esomeprazole, especially:

How is esomeprazole injection given?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Why is esomeprazole used for endoscopy?

Esomeprazole injection is also used to lower the risk of a stomach ulcer bleeding again after an endoscopy treatment. Esomeprazole may also be used for purposes not listed in this medication guide.

How long is esomeprazole good for?

Store mixed esomeprazole injection at room temperature and use it as soon as possible. The mixture will be good for only 6 to 12 hours depending on the type of liquid diluent used. Use a needle and syringe only once and then place them in a puncture-proof "sharps" container.

How is esomeprazole given?

Esomeprazole injection is given as an infusion into a vein. A healthcare provider will give your first dose and may teach you how to properly use the medication by yourself.

What are the side effects of Nexium?

The most common side effects of Nexium may include: Abdominal pain. Constipation. Diarrhea.

When did the FDA add the warnings to Nexium?

The FDA has added at least seven warnings to Nexium labels since 2010. The FDA adds warnings and precautions when evidence shows a drug may cause serious health dangers.

What Is Nexium Used For?

People use prescription Nexium to treat serious stomach acid-related conditions. OTC Nexium treats frequent heartburn.

How long can you take Nexium 24HR?

The FDA warns that patients should never take Nexium 24HR for more than 14 days at a time.

What is the MDL for Nexium?

Nexium lawsuits, part of a multidistrict litigation (MDL) in federal court, claim that the medication caused kidney injuries or damage. As of July 2019, the MDL included 12,775 pending lawsuits over Nexium and other PPIs.

When was Nexium first approved?

Generic Nexium. Teva Pharmaceuticals won FDA approval for the first generic Nexium in 2015. Its generic esomeprazole is a prescription drug. At least eight companies manufactured generic Nexium by 2018.

Is Nexium a prescription drug?

Nexium comes in several versions. It premiered as a prescription drug. Over-the-counter (OTC), generic and store brands followed.

How does esomeprazole work?

It works by blocking the proton pump in the stomach’s cells. When the proton pump is blocked, your stomach makes less acid.

What is esomeprazole magnesium used for?

Esomeprazole magnesium is used to treat conditions caused by too much acid production in your stomach. These conditions include the following:

Can esomeprazole be taken with other medications?

Esomeprazole magnesium oral capsule can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.

Does esomeprazole cause drowsiness?

Esomeprazole magnesium oral capsule doesn’t cause drowsiness, but it can cause other side effects.

Is esomeprazole a prescription drug?

Esomeprazole is a prescription drug. Some forms are also available over the counter, but this article covers the prescription version only.

How to avoid interactions with medications?

To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.

What to do if you have serious side effects?

Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:

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