Precautions
Is Vagifem the same as estradiol?
Vagifem is a vaginal tablet that contains a form of estrogen, called estradiol. While estradiol is naturally made by your body, the estradiol in Vagifem tablets is made in a lab. Vagifem is a brand-name medication that has two generic versions: Yuvafem and estradiol.
Is there a generic for Yuvafem?
A generic version of Yuvafem is available, see estradiol topical prices. Yuvafem (estradiol topical) is a member of the estrogens drug class and is commonly used for Atrophic Urethritis, and Atrophic Vaginitis.
What is another name for Yuvafem?
What Is Yuvafem? Yuvafem (estradiol tablet) is a form of the female hormone estrogen used to treat atrophic vaginitis due to menopause.
Is estradiol generic for Vagifem?
All four medications contain the same active ingredient of estradiol that's used to treat symptoms related to menopause. Generic estradiol, Vagifem, and Yuvafem treat vaginal dryness, thinning, and irritation caused by menopause.
How long can you take Yuvafem?
Yuvafem should be administered intravaginally using the supplied applicator: 1 insert daily for 2 weeks, followed by 1 insert twice weekly (for example, Tuesday and Friday). Generally, women should be started at the 10 mcg dosage strength.
Does Yuvafem make you gain weight?
This drug may cause you to swell or keep fluid in your body. Tell your doctor if you have swelling, weight gain, or trouble breathing.
Can you just stop taking Yuvafem?
Do not start, stop, or change the dosage of any medicines without your doctor's approval. Some products that may interact with this drug include: aromatase inhibitors (such as anastrozole, exemestane, letrozole), fulvestrant, ospemifene, raloxifene, tamoxifen, toremifene, tranexamic acid.
Is estradiol just estrogen?
Estradiol (E2) is the primary form of estrogen in your body during your reproductive years. It's the most potent form of estrogen. Estriol (E3) is the primary form of estrogen during pregnancy.
Is Yuvafem as effective as Vagifem?
Like Vagifem, Yuvafem tablets are used for the treatment for menopausal symptoms. This is the first generic equivalent to Vagifem. Yuvafem delivers the same low dose of vaginal estrogen as Vagifem in a preloaded, single-use, disposable applicator.
Is there a cheaper alternative to Vagifem?
Vagirux, estradiol vaginal tablets, is generic Vagifem. This affordable generic prescription medication is used to treat vaginal atrophy due to estrogen deficiency in postmenopausal women, and now American patients can order it! Compare prices between brand name Vagifem and generic Vagifem and see the cost savings!
Does estradiol cause weight gain?
For women, a specific estrogen hormone called estradiol decreases at menopause helps regulate metabolism and body weight. The lower the levels of estradiol may cause weight gain. Throughout a woman's life, they may notice weight gain around their hips and thighs.
What is a good alternative to Vagifem?
Vagirux - an alternative to Vagifem both are small pessaries inserted into the vagina. The Vagirux is applicator used to insert the pessary into the vagina is reusable unlike the Vagifem applicator making it more environmentally friendly.
What's the difference between Yuvafem and Vagifem?
This is the first generic equivalent to Vagifem. Yuvafem delivers the same low dose of vaginal estrogen as Vagifem in a preloaded, single-use, disposable applicator. Yuvafem will come in packages of 8 or 18 tablets. It is used daily for the first two weeks, then twice weekly.
Is Yuvafem covered by Medicare?
Do Medicare prescription drug plans cover yuvafem? No. In general, Medicare prescription drug plans (Part D) do not cover this drug. Be sure to contact your specific plan to verify coverage information.
Can you just stop taking Yuvafem?
Do not start, stop, or change the dosage of any medicines without your doctor's approval. Some products that may interact with this drug include: aromatase inhibitors (such as anastrozole, exemestane, letrozole), fulvestrant, ospemifene, raloxifene, tamoxifen, toremifene, tranexamic acid.
What can I use instead of Vagifem?
Vagirux - an alternative to Vagifem both are small pessaries inserted into the vagina. The Vagirux is applicator used to insert the pessary into the vagina is reusable unlike the Vagifem applicator making it more environmentally friendly.
What is the difference between generic estradiol, Vagifem, Yuvafem, and Imvexxy?
All four medications contain the same active ingredient of estradiol that's used to treat symptoms related to menopause. Generic estradiol, Vagifem...
Is estradiol a hormone replacement therapy (HRT)?
Yes. Estradiol is a form of estrogen. It's a type of HRT, so it still has the same long-term risks as other estrogen-containing medications.
Does estradiol cause hair loss?
Hair loss is a possible side effect of generic estradiol, Vagifem, and Yuvafem, but it shouldn't be extreme. If you find you've started losing a lo...
How long can you take estradiol safely?
Estradiol, like all estrogen replacement medications, can raise your risk of some serious medical problems, such as breast cancer and blood clots,...
What time of the day should I use estradiol?
You can use estradiol at any time of the day that works with your schedule. Many people prefer to use this medication at bedtime, but this isn't ne...
What are the side effects of Estradiol vaginal tablet (Vagifem)?
With any medication, there are risks and benefits. Even if the medication is working, you may experience some unwanted side effects.
How much does Estradiol vaginal tablet (Vagifem) cost?
For even more savings, use a GoodRx coupon and pay just a fraction of the retail price.
What hormones can you take with a vaginal tablet?
If you still have your uterus, you have to use Estradiol vaginal tablet (Vagifem) with another hormone called progestin to lower your risk of uterine cancer.
Can vaginal irritability be caused by esradiol?
Some people find that the Estradiol vaginal tablet (Vagifem) applicators cause vaginal irritation right after they insert the medication. This is more likely to happen if your menopause symptoms are more severe. This side effect typically gets better or goes away after the medication starts to relieve your vaginal dryness. If the irritation you experience gets worse or is very bothersome, speak with your provider.
Can you take esradiol while pregnant?
Estradiol vaginal tablet (Vagifem) is processed by the liver, so if it's not working properly, you might experience more side effects from this medication. Because of this, if you have or have had any problems with your liver, including liver problems during a past pregnancy, you should not use Estradiol vaginal tablet (Vagifem).
Does vaginal estradiol cause weight gain?
Weight gain is not a typical side effect of Estradiol vaginal tablet (Vagifem). If you notice weight gain after using this medication, contact your provider.
Is esradiol good for menopause?
Estradiol vaginal tablet (Vagifem) is an easy-to-use vaginal tablet that works well for vaginal dryness and irritation caused by menopause. It has very few side effects for most people, but it might be more expensive than other options.
What is Yuvafem?
Yuvafem is a form of estradiol that inserted into the vagina. It is a locally-applied form of hormone therapy that treats menopause symptoms that directly affect the vaginal tissues. Yuvafem can be an appealing option for women who struggle with vaginal low estrogen symptoms who do not want or need the systemic effects of HRT. You must have a prescription from your health care provider to be able to use Yuvafem.
How much does yuvafem cost?
Yuvafem cost. Your insurance carrier may pick up some, or even all, of the Yuvafem cost. Currently, Yuvafem runs anywhere between $47-63 at some of the most well-known pharmacies in the United States, like Walgreens, Walmart, and CVS.
What is the best medicine for dryness in the vagina?
To combat vaginal dryness, many women find success with medication that delivers hormones just to the vaginal tissues. Vagifem was one of the most popular forms of vaginal estrogen but it was quite costly. Fortunately, there is a generic alternative: Yuvafem.
Why does my vagina dry out during menopause?
Vaginal dryness is one of the main symptoms that plague women in menopause. Women experience this frustrating symptom when estrogen levels fall to low levels , which can start in perimenopause and worsen once you reach menopause and postmenopause. [ux_image id=”2607″ height=”56.25%”]
Is Yuvafem a generic?
Yuvafem is like a Vagifem generic medication that is made by a different pharmaceutical company. Both drugs contain estradiol, which is a form of estrogen found in the female body. Because different manufacturers make these medications, there may be variations in concentration, inactive ingredients, delivery, and packaging.
Does insurance cover vagifem?
Unfortunately, insurance does not always cover the cost of menopause medications like Vagifem, which makes women seek out more affordable options. Sometimes, this means that women do not have access to the best medication for them.
Is Yuvafem better than Vagifem?
On average, women report that Yuvafem is less helpful compared to Vagifem. Many women also find the packaging disagreeable because the plastic applicators must be tossed with each use, and it is hard to separate the doses. Positive reviewers state that the product improved thinning vaginal tissues and dryness.
How to use estradiol for menopause?
Apply 1 complete actuation of the pump (1.25 grams of 0.06% estradiol gel that contains 0.75 mg of estradiol) topically to 1 arm once daily; applied in a thin layer over the entire arm on the inside and outside from wrist to shoulder. Generally, when used in a postmenopausal woman with an intact uterus, a progestin should also be considered to reduce the risk of endometrial hyperplasia. Reevaluate periodically as clinically indicated to determine if use is still appropriate. The North American Menopause Society (NAMS) Guidelines support the initiation of hormone replacement therapy (HRT) around the time of menopause if no contraindications to use exist and use is acceptable to the individual patient, as hormone therapy is the most effective treatment for vasomotor and genitourinary symptoms and has been shown to prevent bone loss and fracture. Early initiation of HRT and continuation of use at until the median age of menopause (52 years) is recommended in women with premature natural or surgically induced menopause. HRT for vasomotor symptoms and/or increased risk for bone loss around the time of menopause may be considered in those women aged younger than 60 years or who are fewer than 10 years from menopause onset. For women who initiate HRT more than 10 or 20 years from menopause onset or are aged 60 years or older, the benefit-risk ratio is less favorable due to known risks for HRT (e.g., stroke, myocardial infarction, venous thromboembolism, dementia, urinary incontinence), and guidelines generally recommend against use in these women. Decisions regarding whether to continue systemic HRT in women aged older than 60 years should be made on an individual basis for quality of life, persistent vasomotor symptoms, or prevention of bone loss and fracture, with consideration given to alternative treatments for prevention of bone loss and other health issues.
Where is estradiol metabolized?
Estradiol is extensively metabolized in the gastrointestinal mucosa during oral absorption and in the liver. Micronization of oral estradiol tablets slows oral absorption and decreases the first-pass metabolizm in the liver and increases the normally poor oral bioavailability of estradiol. Absolute bioavailability of oral micronized estradiol is roughly 5% to 10% of an administered dose. The plasma half-life of orally administered estradiol is approximately 1 to 2 hours at steady state; but other circulating estrogens persist longer.
How to increase estradiol dose?
Dose is then increased over time to meet the goals of the individual patient based on age, sexual development, bone age and height, and other treatment goals. Gradually increase dose over about 2 years (e.g. 25, 37.5, 50, 60, 75, 100 mcg/day estradiol delivered via patch) to adult dose for female hypogonadism. Use lowest effective dose. Pubertal induction can be accomplished with transdermal estradiol at an off-label dose as low as 3.1 to 6.2 mcg/day; however, such dosage forms are not commercially available. To allow for normal breast and uterine development, guidelines advise the delay of the addition of progestin (given for 1 week per month) at least 1 to 2 years after starting estrogen or when breakthrough bleeding occurs. Treatment continues for reproductive life.
How to administer estradiol for hypogonadism?
Dose is increased over time to meet the goals of the individual patient based on age, sexual development, bone age and height, and other treatment goals. Gradually increase dose over about 2 years (e.g. 25, 37.5 , 50 , 75 , 100 mcg/day estradiol delivered via patch) to adult dose for female hypogonadism. Use lowest effective dose. Pubertal induction can be accomplished with transdermal estradiol at an off-label dose as low as 3.1 to 6.2 mcg/24 hours; however, such dosage forms are not commercially available. To allow for normal breast and uterine development, guidelines advise the delay of the addition of progestin (given for 1 week per month) at least 1 to 2 years after starting estrogen or when breakthrough bleeding occurs. Treatment continues for reproductive life.
What is the main form of estrogen?
Estradiol is the principal human estrogen#N#Multiple dosage forms are available: oral, topical, transdermal, vaginal, and parenteral#N#Used primarily to treat vasomotor and genitourinary symptoms associated with natural or surgical menopause, to prevent osteoporosis, for female hypogonadism and other conditions associated with estrogen deficiency
How many studies have found that women who used hormonal therapy for menopausal symptoms had an increased risk for?
The primary analysis, using case-control comparisons, included 12,110 cancer cases from the 17 prospective studies.
Can estrogens be used to treat breast engorgement?
Consider the benefits of breast-feeding, the risk of potential infant drug exposure, and the risk of an untreated or inadequately treated condition. Estrogens are not approved for the treatment of postpartum breast engorgement.
What are some things I need to know or do while I take Yuvafem?
Tell all of your health care providers that you take Yuvafem (estradiol vaginal tablets). This includes your doctors, nurses, pharmacists, and dentists.
What are the side effects of Yuvafem?
Call your doctor right away if you have signs of a blood clot like chest pain or pressure; coughing up blood; shortness of breath; swelling, warmth, numbness, change of color, or pain in a leg or arm; or trouble speaking or swallowing. Yuvafem side effects (more detail)
Can you take Yuvafem if you are 65?
Call your doctor right away if you have signs of high calcium levels like weakness, confusion, feeling tired, headache, upset stomach or throwing up, constipation, or bone pain. If you are 65 or older, use Yuvafem (estradiol vaginal tablets) with care. You could have more side effects.
Can estrogen cause uterine cancer?
Estrogens may raise the chance of uterine cancer. Progestins may lower this chance. A warning sign for cancer of the uterus is vaginal bleeding. Report any vaginal bleeding to the doctor.
Can estrogen cause a heart attack?
Using estrogens may raise the chances of having a heart attack, a stroke, breast cancer, ovarian cancer, a blood clot, or dementia. Use estrogens with or without progestin for the shortest time needed at the lowest useful dose.
Can you be allergic to Yuvafem?
If you are allergic to Yuvafem (estradiol vaginal tablets); any part of Yuvafem (estradiol vaginal tablets); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
How many ratings does estradiol have?
Estradiol topical has an average rating of 4.9 out of 10 from a total of 322 rating s for the treatment of Atrophic Vaginitis. 37% of reviewers reported a positive effect, while 48% reported a negative effect.
How often should I use vagifem?
I now only use it once a week and find this sufficient for keeping everything comfortable.
Does estrace burn?
Estrace Vaginal Cream (estradiol): “For those who commented about burning from using Estrace...I also had burning from it. My research led me to believe that the propylene glycol and/or glycerin in the product were the culprits. I switched to a hypoallergenic form of estradiol from a good compounding pharmacy and that solved the problem. No burning and the estradiol was so helpful.”
Is estradiol a compound?
The hypoallergenic estradiol (basically, a compounded version of Estrace from a compounding pharmacy) continues to be very effective for me - relieving vaginal burning/pain and urinary urgency/frequency.
What is the best vaginal pill for menopause?
Activella (estradiol / norethindrone) Relieves vaginal dryness due to menopause. Vagifem (Estradiol Vaginal Tablet) is an easy-to-use vaginal tablet and is a good alternative to oral estrogen pills and patches. Relieves menopause symptoms and lowers your risk of osteoporosis.
What hormones can be used to treat uterine cancer?
If you have your uterus, you might need to use Vagifem (Estradiol Vaginal Tablet) with another hormone called progestin to lower your risk of uterine cancer.
What is yuvafem used for?
Yuvafem (estradiol tablet) is a form of the female hormone estrogen used to treat atrophic vaginitis due to menopause.
What are the side effects of Yuvafem?
Side effects of Yuvafem that are different from Premarin include back pain, diarrhea, vaginal yeast infection, and upper respiratory tract infection.
Can premarin interact with rifampin?
Both Yuvafem and Premarin may interact with seizure medicines, barbiturates, rifampin, ketoconazole, and itraconazole.
When should estrogen be discontinued?
If feasible, estrogens should be discontinued at least 4 to 6 weeks before surgery of the type associated with an increased risk of thromboembolism, or during periods of prolonged immobilization.
Does Yuvafem include all the information needed to use YUVAFEM safely and effectively?
Yuvafem - These highlights do not include all the information needed to use YUVAFEM safely and effectively. See full prescribing information for YUVAFEM. YUVAFEM® (estradiol vaginal ...
Can you use estrogen plus progestin for dementia?
Estrogen plus progestin therapy should not be used for the prevention of cardiovascular disease or dementia [see Warnings and Precautions (5.2, 5.4) and Clinical Studies (14.2, 14.3)].
Is estrogen alone safe for stroke?
The increase in risk was demonstrated in year 1 and persisted [see Clinical Studies (14.2)]. Should a stroke occur or be suspected, estrogen-alone therapy should be dis continued immediately.
Can you take estrogen with progestins?
Estrogens with or without progestins should be prescribed at the lowest effective doses and for the shortest duration consistent with treatment goals and risks for the individual woman.
Is estrogen alone or combined?
Use of estrogen-alone, or in combination with a progestin, should be with the lowest effective dose and for the shortest duration consistent with treatment goals and risks for the individual woman. Postmenopausal women should be re-evaluated periodically as clinically appropriate to determine if treatment is still necessary.
Can estrogen alone be used for dementia?
Estrogen-alone therapy should not be used for the prevention of cardiovascular disease or dementia [see Warnings and Precautions (5.2, 5.4) and Clinical Studies (14.2, 14.3)].
