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is fexofenadine ok to take while pregnant

by Mr. Sim Stehr Published 3 years ago Updated 2 years ago
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As such, we suggest that fexofenadine can be used as equally as the other recommended antihistamines during pregnancy. Accepted for Publication: March 29, 2020.Jun 1, 2020

Precautions

Studies on both fexofenadine and terfenadine have not found an increased chance of birth defects when they are taken during pregnancy. Could taking fexofenadine cause other pregnancy complications?

Is it safe to take fexofenadine or terfenadine during pregnancy?

Miscarriage can occur in any pregnancy. A study looking at people who filled prescriptions for fexofenadine during pregnancy found no increase in miscarriages compared to similar groups who filled prescriptions for other common antihistamines in pregnancy or were not prescribed antihistamines during pregnancy.

Can fexofenadine cause miscarriage?

By: Fexofenadine, most commonly known as Allegra, is an over-the-counter and prescription medication used to treat allergy symptoms. There have been no human studies completely to prove or disprove safety during pregnancy and animal studies have been inconclusive.

Is it safe to take Allegra (fexofenadine) while pregnant?

There is no evidence that fexofenadine would affect a male’s fertility or increase risks to a pregnancy. In general, exposures that fathers or sperm donors have are unlikely to increase the risks to a pregnancy.

Does fexofenadine affect male fertility?

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Can you use fexofenadine when pregnant?

Pregnancy and breastfeeding Fexofenadine is not usually recommended if you're pregnant as there is not a lot of information about its use in pregnancy. Other antihistamines may be more suitable as better safety information is available.

What pregnancy category is fexofenadine?

Fexofendine and desloratidine have been classified as pregnancy category C. Reduction in pup weight and survival were observed with fexofenadine.

Which antihistamine is safest in pregnancy?

Many allergy medications really aren't safe to take during pregnancy. But loratadine (found in Claritin®) and cetirizine (found in Zyrtec® and Alleroff®) are two over-the-counter (OTC) antihistamine medications that doctors consider as being safe to use during pregnancy and while breastfeeding, Dr. Zanotti says.

What is category B in pregnancy?

Category B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.

Is antihistamine safe for pregnant?

Scientific research suggests that using most types of antihistamines during pregnancy is not linked to birth defects. Out of 54 studies examined, 9 studies showed potential links between certain antihistamines and certain birth defects.

What can pregnant woman take for allergies?

These over-the-counter allergy meds have no known harmful effects during pregnancy when you take them according to the package directions.Allegra (fexofenadine)Benadryl (diphenhydramine)Claritin (loratadine)Zyrtec (cetirizine)

How can I treat allergies during pregnancy?

Many allergy drugs may be fine to keep taking during pregnancy, but have the discussion so you can have peace of mind. Oral antihistamines, like cetirizine (Zyrtec), chlorpheniramine (Chlor-Trimeton), diphenhydramine (Benadryl), fexofenadine (Allegra), and loratadine (Claritin) seem to be safe.

How can I get rid of allergies while pregnant?

Step-by-Step Care:Try to avoid your allergy triggers.Use saline nose spray to ease your congestion.Keep animals out of your bedroom.Vacuum often. ... Use the air conditioner to keep humidity low and irritants out of the house. ... Shower and wash your hair after being outdoors if pollen sets off your allergies.More items...•

What is a Category C drug?

Category C. Either studies in animals have revealed adverse effects on the fetus (teratogenic or embryocidal or other) and there are no controlled studies in women, or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the fetus.

Is FEXO 180 safe for pregnancy?

Oral antihistamines, like cetirizine (Zyrtec), chlorpheniramine (Chlor-Trimeton), diphenhydramine (Benadryl), fexofenadine (Allegra), and loratadine (Claritin) seem to be safe.

What hayfever medication is safe in pregnancy?

Loratadine and Cetirizine are the tablets most often prescribed for hay fever during pregnancy. This is because neither causes drowsiness. Chlorphenamine can also be prescribed for use during pregnancy, but it can cause drowsiness, so is not usually the first choice.

Is montelukast and fexofenadine safe in pregnancy?

Exposure to montelukast during pregnancy does not appear to increase the risk of major malformations above the 1% to 3% baseline in the general population. It is important that women are treated effectively for asthma during pregnancy to ensure the best outcome for the mothers.

Can fexofenadine be used in pregnancy?

Due to the limited data, use of fexofenadine should be reserved for cases where no other suitable treatment is available and both prescriber and patient should take into account the relative lack of experience of use in pregnancy.

Is terfenadine safe for pregnancy?

There are insufficient data to determine the risks of adverse pregnancy outcome following use of fexofenadine or terfenadine in pregnancy. The limited published data that are available do not suggest an increased risk of spontaneous abortion, intrauterine death or preterm delivery after maternal exposure. Neither has an increased risk of having an infant with a congenital malformation, low birth weight, neonatal problems or neurodevelopment delay up to one year of age been found following in utero exposure to either fexofenadine and/or terfenadine in pregnancy. The available evidence is, however, very limited.

Is fexofenadine a sedating antihistamine?

Summary. Fexofenadine is a non-sedating antihistamine used for the symptomatic relief of allergic disorders. Although there are very limited data on the use of fexofenadine in pregnancy, this drug is the active metabolite of terfenadine, which was previously considered the non-sedating antihistamine of choice in pregnancy prior to its withdrawal in ...

Can fexofenadine make you pregnant?

Studies have not been done to see if taking fexofenadine could make it harder to become pregnant. Animal studies found no evidence that taking fexofenadine would make it harder to become pregnant.

Can fexofenadine cause breast milk problems?

This dose would be too low to cause problems for the baby. It is possible that antihistamines may lower the amount of milk a woman makes.

Does fexofenadine increase preterm birth weight?

A separate study on terfenadine found no increase in premature delivery or low birth weight when used during pregnancy.

Can you have a miscarriage while on fexofenadine?

Miscarriage can occur in any pregnancy. A study looking at people who filled prescriptions for fexofenadine during pregnancy found no increase in miscarriages compared to similar groups who filled prescriptions for other common antihistamines in pregnancy or were not prescribed antihistamines during pregnancy.

Is fexofenadine sold under Allegra?

Fexofenadine has been sold under brand names such as Allegra® and Aller-Ease®. The medicine terfenadine changes into fexofenadine in the body, so information on terfenadine may also be helpful for predicting the effects of fexofenadine on pregnancy and breastfeeding. I take fexofenadine.

Is fexofenadine an over the counter medication?

What is fexofenadine? Fexofenadine is an over-the-counter antihistamine. Antihistamines are used to reduce the symptoms of allergic reactions and colds, including sneezing, runny nose, watery eyes and itchy throat.

Does fexofenadine cause miscarriage?

Does taking fexofenadine increase the chance for miscarriage? Miscarriage can occur in any pregnancy. Studies have not been done to see if fexofenadine increases the chance for miscarriage.

Is fexofenadine safe for pregnancy?

Fexofenadine is generally considered safe for use during pregnancy under the care and instruction of a physician. If you find out you’re pregnant while taking fexofenadine, contact your gynecologist or prescribing physician immediately.

Can fexofenadine be taken while breastfeeding?

Fexofenadine is excreted during breastfeeding. While there are no known side effects on the infant, the breastfeeding mother could experience reduced milk production. This effect may be increased if the mother is taking pseudoephedrine in combination with fexofenadine.

Can you take tripelennamine with fexofenadine?

While there are no known birth defects or pregnancy complications associated with fexofenadine use during pregnancy, the American Academy of Obstetricians and Gynecologists suggests using either chlorpheniramine or tripelennamine in place of fexofenadine.

Does fexofenadine affect pregnancy?

Use of fexofenadine during pregnancy does not appear to be associated with an increased risk of adverse fetal outcomes. Use of fexofenadine during pregnancy does not appear to be associated with an increased risk of adverse fetal outcomes.

Does fexofenadine cause birth defects?

Fexofenadine use during pregnancy was not associated with an increased risk of major birth defects (prevalence OR, 1.06; 95% CI, 0.81-1.37) or spontaneous abortion (HR, 0.93; 95% CI, 0.82-1.07) compared with cetirizine use during pregnancy.

Is there any controlled data on human pregnancy?

There are no controlled data in human pregnancy. AU TGA pregnancy category B2: Drugs which have been taken by only a limited number of pregnant women and women of childbearing age , without an increase in the frequency of malformation or other direct or indirect harm ful effects on the human fetus having been observed.

Can fexofenadine be excreted into milk?

Excreted into human milk: Yes (fexofenadine and pseudoephedrine) Comments: -Peak steady state fexofenadine milk levels (after administration of the parent compound terfenadine) averaged 41 mcg/L (range 23 to 60 mcg/mL). -It is estimated the infant would be exposed to about 0.1% of the parental fexofenadine dose.

Does pseudoephedrine cause gastroschisis?

Pseudoephedrine may be associated with gastroschisis, but this may also be caused by maternal health factors. First trimester oral decongestant exposure or maternal smoking may increase the risk of gastroschisis, small intestinal atresia (SIA), and hemifacial microsomia. There are no controlled data in human pregnancy.

Is Allegra ok for a baby?

Allegra (fexofenadine) Ok: but sudafed is questionable due to potential side effects. The most critical period is during the 1st trimester when the baby's organs are developing ... Read More

Can you give Claritin to a baby?

Yes!: Try Claritin (loratadine) or allegra. You are well out of the period of organogenesis (4-8 weeks, when the organs are forming) so your baby should be ... Read More

Is it safe to take allegra (fexofenadine) d or sudafed while pregnant if you are sick?

Allegra (fexofenadine) Ok: but sudafed is questionable due to potential side effects. The most critical period is during the 1st trimester when the baby's organs are developing... Read More

Can you take decongestants during the first trimester?

During your first trimester, don't take decongestants by mouth, either. They may make some birth defects more likely. Watch out for antihistamines combined with a decongestant. Since there's not enough evidence for their safety, avoid antihistamine nasal sprays.

Is it better to take medication for allergies?

But if allergy symptoms are a big problem -- making it hard to sleep, for instance -- taking medication may be better for your health and your baby's.

Can you take allergy medicine while pregnant?

Many allergy drugs may be fine to keep taking during pregnancy, but have the discussion so you can have peace of mind. Oral antihistamines, like cetirizine ( Zyrtec ), chlorpheniramine (Chlor-Trimeton), diphenhydramine ( Benadryl ), fexofenadine ( Allegra ), and loratadine ( Claritin) seem to be safe. So does cromolyn sodium ( Nasalcrom) ...

Can you get allergy shots while pregnant?

Yes, you can keep getting allergy shots while you are pregnant. But you shouldn't start allergy shots during pregnancy. Wait until after you've had your baby.

Is it safer to skip allergy medication altogether when I'm pregnant?

If your symptoms aren't bad, your doctor may suggest other treatments instead. You could allergy-proof your home or rely on saline nasal sprays.

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General Precautions

Fexofenadine is an antihistamine used to relieve allergy symptoms such as watery eyes, runny nose, itching eyes/nose, sneezing, hives, and itching.

Status: Discontinued

May Treat: Allergic rhinitis · Chronic idiopathic urticaria · Seasonal allergic rhinitis

Drug Class: Antihistamines - 2nd Generation · Antihistamines - 2nd Generation - Piperidines

Availability: Prescription sometimes needed

Pregnancy: Consult a doctor before using

Status: Discontinued

May Treat: Allergic rhinitis · Chronic idiopathic urticaria · Seasonal allergic rhinitis

Drug Class: Antihistamines - 2nd Generation · Antihistamines - 2nd Generation - Piperidines

Availability: Prescription sometimes needed

Pregnancy: Consult a doctor before using

Lactation: Consult a doctor before using

Alcohol: Limit intake while taking this medication

Driving: May cause drowsiness or dizziness. Use caution

Manufacturer: SANOFI-AVENTIS

Precautions

  • Avoid taking with apple, grapefruit, orange juice.
  • Avoid aluminum/magnesium antacids within 2 hours.
  • Check warnings on OTC medications.

  • Avoid taking with apple, grapefruit, orange juice.
  • Avoid aluminum/magnesium antacids within 2 hours.
  • Check warnings on OTC medications.
  • Tell doctor if you have kidney problems
  • Call doctor if you are not getting better
  • Room temperature
  • For capsule products : May take with or without food. Protect from heat, light, & moisture.
  • For suspension, oral products : Shake well & measure with dosing spoon/cup/syringe.
  • For tablet, disintegrating products : Open with dry hands and place tablet on tongue. Place tablet on tongue to dissolve it. Take on an empty stomach.

Effect While Trying to Conceive

Effects on Pregnancy

Safe During Breastfeeding

1.Fexofenadine Use During Pregnancy | Drugs.com

Url:https://www.drugs.com/pregnancy/fexofenadine.html

24 hours ago Web · Fexofenadine Pregnancy Warnings. Use is not recommended unless clearly needed. Animal models have failed to reveal evidence of teratogenicity. Decreased dose-related pup weight gain and survival occurred at 3 times the maximum recommended human dose. There are no controlled data in human pregnancy.

2.USE OF FEXOFENADINE IN PREGNANCY - medicines …

Url:https://www.medicinesinpregnancy.org/bumps/monographs/USE-OF-FEXOFENADINE-IN-PREGNANCY/

16 hours ago WebSummary. Fexofenadine is a non-sedating antihistamine used for the symptomatic relief of allergic disorders. Although there are very limited data on the use of fexofenadine in pregnancy, this drug is the active metabolite of terfenadine, which was previously considered the non-sedating antihistamine of choice in pregnancy prior to its ...

3.Fexofenadine - MotherToBaby

Url:https://mothertobaby.org/fact-sheets/fexofenadine-pregnancy/

23 hours ago WebThis sheet is about exposure to fexofenadine in pregnancy and while breastfeeding. This information should not take the place of medical care and advice from your healthcare providers. What is fexofenadine? Fexofenadine is an over-the-counter antihistamine. Antihistamines reduce the symptoms of allergic reactions and colds, including sneezing, …

4.Is Allegra Safe During Pregnancy and Breastfeeding?

Url:https://www.babymed.com/medications/fexofenadine-allegra-during-pregnancy-and-breastfeeding

23 hours ago Web · Importance: Fexofenadine hydrochloride is a frequently used drug for treatment of allergic conditions during pregnancy, but the fetal safety of fexofenadine use has not been well studied. Objective: To investigate the risk of adverse fetal outcomes associated with fexofenadine use during pregnancy. Design, setting, and participants: …

5.Association Between Fexofenadine Use During …

Url:https://pubmed.ncbi.nlm.nih.gov/32478810/

2 hours ago Web · Fexofenadine / pseudoephedrine Pregnancy Warnings. This drug should not be used during pregnancy unless the benefit outweighs the risk to the fetus. -Pseudoephedrine use during the first trimester may be associated with gastroschisis and small intestinal atresia (SIA); data is limited and unconfirmed, risk appears to be low (only …

6.Fexofenadine / pseudoephedrine Use During Pregnancy …

Url:https://www.drugs.com/pregnancy/fexofenadine-pseudoephedrine.html

9 hours ago WebALLEGRA should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Nonteratogenic Effects. Dose-related decreases in pup weight gain and survival were observed in rats exposed to an oral dose of 150 mg/kg of terfenadine (approximately 3 times the maximum recommended human daily oral dose of ...

7.taking fexofenadine hcl 180mg while pregnant

Url:https://www.medhelp.org/posts/Womens-Health-Postpartum/taking-fexofenadine-hcl-180mg-while-pregnant/show/176463

34 hours ago Web · The authors concluded that Allegra during pregnancy did not lead to an increased risk of major birth defects or other adverse fetal outcomes. The results suggest that Allegra can be added to other second-generation antihistamines currently considered safe for use by pregnant women. Allergic rhinitis is the most common cause of rhinitis in ...

8.Can I take allegra while pregnant | Answers from Doctors …

Url:https://www.healthtap.com/q/can-i-take-allegra-while-pregnant/

10 hours ago WebObstetrics and Gynecology 30 years experience. Yes: In general allegra, zyrtec, benadryl, (diphenhydramine) and Claritin are all ok for allergies ( as well as many others) during pregnancy. Follow the d... Read More. 5.6k views Reviewed >2 years ago. Thank. Dr. George Klauber agrees. 8 thanks.

9.Can I Take Allergy Medication If I'm Pregnant? - WebMD

Url:https://www.webmd.com/allergies/allergy-medication-pregnant

2 hours ago WebMany allergy drugs may be fine to keep taking during pregnancy, ... (Chlor-Trimeton), diphenhydramine , fexofenadine , and loratadine seem to …

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