
The main ingredient in PetArmor and Frontline Plus
Fipronil
Fipronil is a broad-spectrum insecticide that belongs to the phenylpyrazole chemical family. Fipronil disrupts the insect central nervous system by blocking GABA-gated chloride channels and glutamate-gated chloride channels. This causes hyperexcitation of contaminated insects' nerves …
Is Fipronil safe for dogs?
Fipronil, a chemical insecticide, is the primary active ingredient in the various Frontline products. While promoted as generally safe, it can have some negative effects on a variety of your dog’s systems. Side Effects and Precautions for Frontline
What are the active ingredients in fipronil?
The product contains 9.8% fipronil and 8.8% (S) – Methoprene as its active ingredients. Fipronil is an insecticide that kills adult fleas by disrupting their nervous system. The (S)-methoprene is a growth regulator and stops the development of the immature stages of the flea life cycle (the eggs and the larvae).
Are fleas resistant to fipronil?
there did not appear to be significant resistance among fleas to fipronil. Because of its effectiveness on various pests, fipronil is used as the active ingredient in flea control products for pets and home roach traps as well as field pest control for corn, golf courses, and commercial turf.
What is Fipronil used for?
Because of its effectiveness on a large number of pests, fipronil is used as the active ingredient in flea control products for pets and home roach traps as well as field pest control for corn, golf courses, and commercial turf. Its widespread use makes its specific effects the subject of considerable attention.

Is Frontline a fipronil?
Frontline Spot On is a treatment for both cats and dogs that provides long-lasting protection against fleas and ticks, and controls biting lice. Frontline Spot On contains fipronil, a phenylpyrazole licensed for use as a veterinary medicine. Fipronil is not an organophosphate compound.
What is the generic name for fipronil?
Fluocyanobenpyrazole Taurus TermidorFipronilNamesOther names Fipronil Fluocyanobenpyrazole Taurus TermidorIdentifiersCAS Number120068-37-33D model (JSmol)Interactive image30 more rows
What is the brand name for fipronil?
Fipronil (brand names: Frontline®, Barricade®, Easyspot®, Effipro®, Sentry Fiproguard®, Parastar®, PetArmor®, Pronyl OTC®, Spectra Sure®, and many others) is a topical medication used to treat fleas, ticks, and chewing lice infestations in dogs and cats.
Does Frontline Plus have fipronil?
The active ingredient of Frontline Plus is Fipronil, a topical insecticide which destroys fleas, flea larvae, and ticks.
What if my dog licks fipronil?
Treated animals can ingest fipronil through licking or grooming. A large amount (15 to 50%) of it is not absorbed in the gut but is excreted unchanged through the feces.
How often can you apply fipronil?
Recommended application intervals for fipronil spot ons are as follows: Spray: up to 12 wks for fleas on dogs and 8 wks for fleas on cats; FAD apply monthly; 3 wks for paralysis ticks, 4 wks for brown dog tick. Dog spot ons: monthly for fleas, FAD and brown dog tick; 2 wkly for paralysis tick.
What are the side effects of fipronil?
Clinical signs and symptoms reported after ingestion of fipronil by humans include sweating, nausea, vomiting, headache, abdominal pain, dizziness, agitation, weakness, and tonic-clonic seizures. Clinical signs of exposure to fipronil are generally reversible and resolve spontaneously.
How safe is fipronil?
The EPA has determined fipronil to be safe for use on dogs and cats, with no harm to humans who handle these animals. Poisoning cases from accidental use or misuse of fipronil may occur in animals.
What insecticide has fipronil?
Products such as Martin's Prefurred Plus, Maxforce FC Select Roach Bait, Maxforce FC Roach Bait, Maxforce Magnum, Maxforce FC Ant Bait, Maxforce Carpenter Ant Bait, Taurus SC, FUSE Termiticide/Insecticide, and Termidor SC contain Fipronil.
What percentage of fipronil is in frontline?
9.8%Brand Names and Other Names of Fipronil Other veterinary formulations: Fipronil is an ingredient in Frontline Plus® where it is dispensed in a product that contains 9.8% fipronil and 8.8% methoprene.
Which Frontline is the best?
Frontline Plus is our top nonprescription recommendation because it kills ticks and fleas, controls flea infestations, and kills chewing lice, all with one easy application. When used primarily for flea control, each dose of Frontline Plus lasts up to three months.
Has Frontline Plus stopped working?
Although Frontline Plus may kill 100 percent of the fleas immediately after you put it on your dog, its effectiveness will diminish throughout the month. If the fleas in your dog's environment are really bad, a few fleas may slip through, especially toward the end of the month.
What insecticide has fipronil?
Products such as Martin's Prefurred Plus, Maxforce FC Select Roach Bait, Maxforce FC Roach Bait, Maxforce Magnum, Maxforce FC Ant Bait, Maxforce Carpenter Ant Bait, Taurus SC, FUSE Termiticide/Insecticide, and Termidor SC contain Fipronil.
What type of insecticide is fipronil?
Fipronil is a broad use insecticide that belongs to the phenylpyrazole chemical family. Fipronil is used to control ants, beetles, cockroaches, fleas, ticks, termites, mole crickets, thrips, rootworms, weevils, and other insects.
Is fipronil the same as Termidor?
The active ingredient in Termidor is Fipronil, which is also used in many other products, including spot-on flea treatments for pets.
Which is better fipronil or imidacloprid?
At 12 hours, imidacloprid achieved 99.3% efficacy versus 59.7% for selamectin and 89.6% for fipronil-(S)-methoprene. The study presented here confirmed that imidacloprid provides high and early efficacy. Six hours after treatment, flea counts in the imidacloprid group were already reduced by more than 60%.
What is the effect of fipronil on bees?
Fipronil is one of the main chemical causes blamed for the spread of colony collapse disorder among bees. It has been found by the Minutes-Association for Technical Coordination Fund in France that even at very low nonlethal doses for bees, the pesticide still impairs their ability to locate their hive, resulting in large numbers of forager bees lost with every pollen-finding expedition. A synergistic toxic effect of fipronil with the fungal pathogen Nosema ceranae was recently reported. The functional basis for this toxic effect is now understood: the synergy between fipronil and the pathogenic fungus induces changes in male physiology leading to infertility. A 2013 report by the European Food Safety Authority identified fipronil as "a high acute risk to honeybees when used as a seed treatment for maize and on July 16, 2013 the EU voted to ban the use of fipronil on corn and sunflowers within the EU. The ban took effect at the end of 2013."
What is the chemical family of fipronil?
Chemical compound. Fipronil is a broad-spectrum insecticide that belongs to the phenylpyrazole chemical family. Fipronil disrupts the insect central nervous system by blocking GABA -gated chloride channels and glutamate-gated chloride (GluCl) channels. This causes hyperexcitation of contaminated insects' nerves and muscles.
How many eggs contain fipronil?
Chicken eggs were found to contain Fipronil and distributed to 15 European Union countries, Switzerland, and Hong Kong. Approximately 700,000 eggs are thought to have reached shelves in the UK alone. Eggs at 44 farms in Taiwan were also found with excessive Fipronil levels.
What is the active ingredient in Frontline Topspot?
Fipronil is the main active ingredient of Frontline TopSpot, Fiproguard, Flevox, and PetArmor (used along with S-methoprene in the 'Plus' versions of these products) in the USA and Frontline Tri-Act for Dogs, Plus (Dog), Plus (Cat), Spot-On (Dog) and Spot-On (Cat) in the UK; these treatments are used in fighting tick and flea infestations in dogs and cats.
How much does fipronil affect daphnids?
An invertebrate lifecycle daphnia study showed that fipronil affects length in daphnids at concentrations greater than 9.8 ppb.
Why are there mass bee deaths in France?
In May 2003, the French Directorate-General of Food at the Ministry of Agriculture determined that a case of mass bee mortality observed in southern France was related to acute fipronil toxicity. Toxicity was linked to defective seed treatment, which generated dust.
How is fipronil quantitated?
Fipronil may be quantitated in plasma by gas chromatography-mass spectrometry or liquid chromatography-mass spectrometry to confirm a diagnosis of poisoning in hospitalised patients or to provide evidence in a medicolegal death investigation.
Are there safe alternatives? Even in flea or tick infested areas?
Ticks are very serious, heartworms are nasty, and so are fleas – to us and our dogs. But can you imagine dumping pesticides into the blood stream of your infant or child? Lather an insecticide on them that entered their bloodstream? Something that had the above cautions associated with it? Or would you try to find a better way first?
What is the active ingredient in Perrigo PetArmor Plus?
The active ingredient in pesticide preventatives Frontline and Perrigo PetArmor Plus is Fipronil. What is Fipronil? I wrote about Fipronil earlier in a post on this blog, explaining:
What oils should I use for my dog?
I choose to use a selection of healthy oils and plants. Some examples include turmeric, coconut oil, a source of omega fatty acids, garlic, and brewers yeast.
Where is Jen DeHaan?
Jen deHaan is graphic designer, small business owner, and dog person living in Bay Area, California. Jen enjoys learning about dog training and behavior, and has taken several courses and seminars since 2010. She also contributes articles to leading websites, such as Victoria Stilwell's Positively . It all started with a great dog called Mikey (aka "dude"), loved and lost but remembered forever.
Is fipronil toxic to dogs?
It’s important to understand that Fipronil is toxic and enters the bloodstream of your dog, whatever way you slice it or dose you provide. In a study of chronic toxicity, where rats were fed fipronil daily for 52 weeks, researchers found changes in thyroid hormones, increased liver mass, and effects on the kidney.
Is fipronil a carcinogen?
Another concerning aspect of this toxin is that “fipronil has been classified by the EPA as a Group C (possible human) carcinogen based on an increase in thyroid follicular cell tumors in both sexes of the rat.”.
Is curry and pepper oil toxic?
So true, these toxic chemicals are so strong that over a period of time they build up toxins in their body. Natural alternatives are best. Both Curry and Brownie have been off frontline and monthly worm pills for a year now and have been clear of fleas and worms. I've been using the Curry n Pepper flea away oil once a week, with an additional application before heading out on hikes for added protection. The oil is non-toxic, moisturizes the skin and helps keep fleas, tick, mange and mites at bay.
What is Bravecto dog food?
Bravecto is a once quarterly chewable that comes in a tasty beef flavor for your dog. It’s intended to mimic an awesome treat instead of forcing a pill down your pet’s throat.
How to get rid of fleas and ticks on dog?
Using a convenient applicator, you gently part the hair in a line down your pet’s back and distribu te the liquid. It gently rubs into the skin where the natural oils of the coa t help distribute it throughout your pet’s coat. Both methods are waterproof and begin to kill fleas and ticks within hours.
How does Fipronil work on dogs?
It interrupts the breeding cycle of the flea and kills both eggs and larva until the flea population is gone . It goes one step further to repel fleas and ticks, so your dog can find relief even if you have a problem in your yard. It begins to work within hours, and you should see a noticeable reduction in fleas within the first 12 hours. It requires monthly applications to maintain efficacy.
How long does it take for a flea killer to work?
It begins to work within hours of the dose, and within eight hours, 100% of fleas are dead.
How effective is Bravecto's method?
Preliminary studies have shown it to be more effective for keeping fleas at bay and marginally more effective for ticks. The technique requires little work and protects your dog for up to three months at a time.
How to calm a cat that can't see?
When your cat is ready to relax, gently stroking your cat with one hand and parting the hair can help get the treatment on before your cat has had enough. Cats are sometimes calmer if they can’t see. You can purchase a “kitty muzzle,” something that fits over your cat’s eyes without blocking breathing.
How to get a spot on treatment for cats?
Depending on your cat’s personality, you may want to play a game with your cat or take your cat on a walk. When your cat is ready to relax, gently stroking your cat with one hand and parting the hair can help get the treatment on before your cat has had enough.
What Are Fleas?
The common flea or Ctenocephalides Canis is nearly a microscopic insect that feeds on the blood of dogs, cats, and even humans.
What Are Ticks?
Dermacentor Variabilis, also known as a tick is a small blood-sucking menace similar to the flea, but much larger.
How Do I Know If My Pet Has Fleas/Ticks?
Fleas and ticks are incredibly annoying to your pet and your life. In some cases, fleas and ticks are obvious, other times infestations can be exceptionally hard to detect.
Are Flea & Tick Treatments Different for Cats & Dogs?
Yes. Flea and tick treatments for dogs and cats can vary dramatically regarding active ingredient and prescribed dosage.
What is Nexgard delivered?
Delivered orally. Eliminates, fleas, ticks + eggs and larvae. Key ingredients: afoxolaner. NexGard, on the other hand, features afoxolaner which, unlike most other flea and tick treatments is designed to be delivered orally via a beef-flavored bite-sized chewable.
What is the ingredient in Frontline?
Eliminates, fleas, ticks + eggs and larvae. Key ingredients: fipronil & methoprene. Frontline features two main ingredients; fiproni l, designed to kill adult fleas and ticks, and methopren e, which destroys flea eggs and larvae.
Why is Frontline so effective?
The second reason Frontline works so well is due to its active ingredients, fipronil, and methoprene. When combined in the topical treatment, fipronil and methoprene create a powerful barrier of protection and prevention for your pet against fleas, ticks, and lice in every stage of their life.
Review Summary
One of the most important things you can do for your dog is to give them a regular flea treatment. In addition to sparing them from the discomfort and irritation that the little biting insects can cause, an effective flea treatment can also keep certain diseases at bay.
What Are the Differences Between Them?
As noted above, both treatments are similar in terms of effectiveness, but that doesn’t mean that they’re identical. In fact, they have several key differences, as we’ll highlight below.
How effective are they against fleas?
Generally speaking, Fipronil (the active ingredient in Frontline) has been shown to be a bit more effective at killing fleas than the ingredients in K9 Advantix. Fipronil also requires lower dosages to be effective, which may be appealing to owners who aren’t crazy about rubbing chemicals on their pet’s skin.
What about other insects?
Both are effective at killing ticks, and Frontline is probably superior in that regard. However, only K9 Advantix repels them.
Which product is safer?
Both have been shown to be completely safe for dogs, although Frontline is probably safer for pregnant or nursing animals (consult your vet before giving a pregnant dog K9 Advantix). Also, both can potentially cause skin irritation, so be sure to monitor your dog after application.
Which product is cheaper?
K9 Advantix tends to be a bit less expensive than Frontline, although the difference is marginal, usually only a few bucks or so. The price difference will vary depending on where you buy your flea treatments as well.
Which product lasts longer?
Both are designed to last for one month after application. Both are also waterproof once they’ve been absorbed into the skin, so you can bathe your dog or let them take a dip in the pool without compromising the medicine’s effectiveness.
What insecticide kills fleas?
Fipronil is an insecticide that kills adult fleas by disrupting their nervous system. The (S)-methoprene is a growth regulator and stops the development of the immature stages of the flea life cycle (the eggs and the larvae).
What is the most common type of flea?
Fleas are the number one parasite that veterinarians see in practice. The most common type of flea is Ctenocephalides felis (the cat flea) which can infect cats, dogs, and rabbits as well as biting humans too, causing itchiness but also transmitting disease. An adult flea is brownish-red in color, wingless, and approximately 1-3mm in size.
How old is Frontline Plus?
Frontline Plus is safe to use in puppies 8 weeks of age and older. The application of the product is similar to PetArmor Plus. Open the pipette as per packet guidelines, apply the liquid contents to the skin on the back of the dog’s neck (parting the fur to allow access to the skin itself).
How long does it take for PetArmor Plus to kill fleas?
PetArmor Plus states on their website that fleas on your pet are killed within 24 – 48 hours after application.
How long does PetArmor Plus last?
PetArmor Plus is a product that is effective against fleas, flea eggs, flea larvae, ticks, and chewing lice. It comes as a liquid medication in small individual pipettes that need to be applied to the skin on the back of the dog. They are available to buy in packs of 3, 6, or even 12 from some retailers. It lasts up to 30 days when applied, so monthly reapplication is advised to prevent any reinfestations.
How to kill pupal cocoon?
To treat the home, you can use chemical sprays to kill eggs and larvae, but not many products will touch the resistant pupal cocoon, so this will require patience. As they all eventually hatch out and hop onto your pet, they will then come into contact with the parasite product and die (but this process which could take several weeks). You can speed things up by increasing the temperature and humidity in your home (damp towels on radiators and boiling kettles in rooms), hot washing bedding, and lots of hoovering as the vibrations help cause hatching to occur faster.
How old is a puppy when it is safe to use a saline solution?
It is safe to use in puppies from 8 weeks of age onwards.
How to Use Frontline on Chickens?
Whether taken orally or applied topically, the chicken’s body absorbs a certain degree of Fipronil in the fatty tissues. After some time, the body breaks down the active ingredient straight into the bloodstream.
Is Frontline Safe for Chickens?
Rarely would reliable animal experts use Frontline on chickens for pest control. As mentioned above, Frontline can cause a whole load of ugly reactions on fowls, mainly when used for long periods.
Can You Spray Chickens with Permethrin?
Permethrin is one of the most preferred treatments for scabies and lice in humans. Unknown to most people, a 10% spray of Permethrin is equally effective in eradicating lice in chicken coops. The brighter side is that it has low toxicity compared to other chemical pesticides.
What do Frontline Plus and K9 Advantix II actually do?
Both of these products are licensed for the treatment and prevention of ectoparasitic infestations. This means they kill and protect your pet against parasites that live in their fur and skin .
Who scores better on price?
The cost of both of these products depends on the size of your pet so here we review doses for small dogs, the larger your pooch, the more expensive the product will be.
How long does K9 Advantix last?
At a brief glance, Frontline Plus and K9 Advantix II seem to be very similar, both are topical, waterproof products that last for approximately 30 days. The largest difference is the extra action K9 Advantix II has in repelling mosquitoes and biting flies.
What is the K9 Advantix II?
K9 Advantix II targets the nervous system of insects and arthropods which causes them to lose coordination, become paralyzed, and then die.
How old can a dog be to use Frontline Plus?
What We Like About Frontline Plus. Can be used on puppies only 8 weeks old once they’re heavier than 4.4lbs. Suitable to be used for pregnant and lactating bitches.
How long does Frontline Plus last?
Frontline Plus works consistently for 30 days, protecting your dog from re-infestation.
What is Frontline Plus?
Frontline Plus is a topical spot-on medication. It’s sold in pre-measured ampoules that you simply snap open, part the fur between your pup’s shoulder blades and squeeze the contents onto their skin.
How does Nexgard work?
The chemicals that Frontline and Nexgard use are different, but they both target the flea’s nervous system by overstimulating them until they are killed. Both flea treatments also stop eggs and flea larvae from developing further into adult fleas.
How long does Frontline flea treatment last?
Frontline provides your pet with reliable flea protection against current and any future fleas for a full 30 days. It is not ideal to reapply the flea treatment until the month has completely ended. If possible, try to administer Frontline on the same day of each month.
What is the name of the flea killer in Nexgard?
The main flea killing ingredient in a Nexgard pill is called Afoxolaner. Afoxolaner is specifically designed to kill fleas in dogs by disrupting a flea’s central nervous system. Fleas who come in contact with Afoxolaner will cause them to go into hyperexcitation, or overstimulation, that causes death.
What is the best flea treatment for dogs?
The most common flea treatments are topical and ingested flea treatments. Two types of flea treatments are Nexgard and Frontline. Nexgard for dogs is an orally ingested flea treatment while Frontline is applied directly onto the skin. Both are quality flea treatments, but when it comes to putting Nexgard vs.
What is the ingredient in Frontline?
Ingredients. Frontline uses two bug-killing ingredients to manage any flea and tick infestation. The first ingredient is Fipronil, which is a broad-spectrum insecticide that can kill adult fleas and ticks when ingested or through contact by hyper-stimulating their nervous system.
How old can a dog be to take Nexgard?
You can use Nexgard on both puppies and dogs, but only if your puppy is over eight weeks of age and weighs more than four pounds. The reason your puppy has to reach the weight and age limit is so to not upset their delicate stomachs.
How long does it take for a dog to die from fleas?
Once Frontline has been applied to your pet, fleas should start being killed off in about four hours. In about 12 hours, all of the fleas should have been killed off your pet. One of the highlights of Frontline is that the flea does not have to bite your dog to be killed.
