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is it safe to use insulin during pregnancy

by America Raynor Published 2 years ago Updated 2 years ago
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Insulin is the traditional first-choice drug for blood sugar control during pregnancy because it is the most effective for fine-tuning blood sugar and it doesn't cross the placenta. Therefore, it is safe for the baby. Insulin can be injected with a syringe, an insulin pen, or through an insulin pump.

Is Supradyn safe during pregnancy?

Yes, you can take supradyn during pregnancy. It is advisable to consult your gynecologist for more details before starting any supplement. 5. Can I drive while using Supradyn Tablet? Yes, Supradyn Tablet is completely safe and does not cause any drowsy feeling. 6. Is using Supradyn Tablet addictive?

Is Sinupret safe during pregnancy?

There is no consensus regarding the use of Sinupret during lactation and during pregnancy. According to experts, the drug does not have such a pronounced effect as antibiotics. It only relieves the symptoms, improving the overall condition.

Is HCG safe during pregnancy?

The use of HCG injection during early pregnancy has a number of side effects that must not be ignored. It also tends to aggravate some of the pregnancy symptoms like queasiness, pain and sensitivity of breasts, etc.

Are psychotropic drugs safe to use during pregnancy?

The use of psychotropic drugs in pregnant patients has some risk. However, the risk of major congenital malformation was not high according to the above study. Furthermore, the disorder itself and the abnormal disorder-related behavior and the physical symptoms had critical impact on whether the medication was teratogenic.

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What are the risks of taking insulin during pregnancy?

Are there any side effects of taking insulin during pregnancy? The main insulin side effect during pregnancy is that it could cause low blood sugar levels (hypoglycemia) in case you missed/delayed a meal or injected excess insulin.

When should I take insulin during pregnancy?

Meal time insulin: Inject it 5 to 10 minutes before your meal (or within 5 to 10 minutes after if you are suffering with sickness). Never have your meal time insulin then not eat. Bed time Insulin: Inject it just before going to bed.

How many units of insulin is safe during pregnancy?

In the first trimester, the total daily insulin requirement is 0.7 units/kg/day, in the second trimester it is 0.8 units/kg/day, and in the third trimester it is 0.9-1.0 units/kg/day.

Does insulin injection affect baby during pregnancy?

Insulin doesn't cross the placenta, which means it can't get to your baby, so it's safe to use as prescribed.

Is metformin or insulin better during pregnancy?

Maintaining blood sugars in the normal range decreases these pregnancy complications. We hypothesize that metformin will achieve similar levels of blood sugar control compared to insulin. In doing so, metformin will prevent the increased risk of pregnancy complications associated with T2DM in pregnancy.

Does insulin cause weight gain in pregnancy?

[26] reported that pregnant women prescribed insulin therapy had higher BP and weight gain than those given metformin.

Which insulin is best for pregnancy?

use of isophane insulin (NPH insulin) as the first choice for long‐acting insulin during pregnancy is recommended, and insulin Detemir or Glargine in women with diabetes who have established good blood glucose control before pregnancy (NICE 2015);

What are the disadvantages of taking insulin?

On the negative side, insulin carries a high risk of low blood sugar reactions if too much is used, and many people gain weight when treated with insulin.

Which insulin is preferred in pregnancy?

Insulin detemir is preferred over insulin glargine because it has been studied more extensively in pregnancy and can be dosed twice per day more predictably than glargine, as previously mentioned. (See "General principles of insulin therapy in diabetes mellitus", section on 'Safety'.)

Can a diabetic mom have a healthy baby?

If a woman with diabetes keeps her blood sugar well controlled before and during pregnancy, she can increase her chances of having a healthy baby. Controlling blood sugar also reduces the chance that a woman will develop common problems of diabetes, or that the problems will get worse during pregnancy.

What blood sugar level requires insulin?

Insulin therapy will often need to be started if the initial fasting plasma glucose is greater than 250 or the HbA1c is greater than 10%.

What happens to baby if mother is diabetic?

Infants of diabetic mothers (IDM) are often larger than other babies, especially if diabetes is not well-controlled. This may make vaginal birth harder and may increase the risk for nerve injuries and other trauma during birth. Also, cesarean births are more likely.

What blood sugar level requires insulin?

Insulin therapy will often need to be started if the initial fasting plasma glucose is greater than 250 or the HbA1c is greater than 10%.

How do you start insulin during pregnancy?

We begin with a single injection of 10 to 20 units of intermediate-acting basal insulin (neutral protamine Hagedorn [NPH]) and 6 to 10 units of rapid-acting insulin (lispro or aspart) in the morning immediately before breakfast; the dose within this range is based on the degree of elevation above target levels.

How much sugar level is normal in pregnancy?

We suggest the following target for women testing blood glucose levels during pregnancy: Before a meal: 95 mg/dl or less. One hour after a meal: 140 mg/dl or less. Two hours after a meal: 120 mg/dl or less.

What happens if I don't take insulin with gestational diabetes?

She may need up to three times as much insulin. Gestational diabetes starts when your body is not able to make and use all the insulin it needs for pregnancy. Without enough insulin, glucose cannot leave the blood and be changed to energy. Glucose builds up in the blood to high levels, called hyperglycemia.

Why is insulin prescribed during pregnancy?

Therefore, insulin is required and may be prescribed to keep your blood glucose levels in control (2). Blood glucose levels during conception and pregnancy are important to be normal both for development of a healthy fetus and to maintain normal fetal growth and development.

Why is insulin important for gestational diabetes?

Insulin is crucial to protect the mother and the growing baby from the effects of gestational diabetes. However, the injection itself might have a few side effects, such as (9): If you experience any of the following symptoms, call your doctor.

Does Insulin Affect The Baby During Pregnancy?

ADA says that insulin does not cross the placenta, and so it does not affect the baby.

Are There Any Side Effects Of Using Insulin During Pregnancy?

Insulin is crucial to protect the mother and the growing baby from the effects of gestational diabetes. However, the injection itself might have a few side effects, such as (9):

What Is The Suggested Drug Therapy For Treating Gestational Diabetes?

The guidelines of the American College of Obstetricians and Gynecologists (ACOG) recommend insulin as the first-line treatment for gestational diabetes that cannot be controlled by dietary and lifestyle changes.

Can you take insulin while pregnant?

In clinical practices, insulin is the first-line of treatment for type1 and type 2 diabetes and uncontrolled GD during pregnancy (3). According to the American Diabetes Association (ADA), insulin administered through injection, insulin pen, or through an insulin pump is safe for pregnant women (4). Your doctor will put you on insulin only ...

Does insulin help with pregnancy?

Usually, a balanced diet and regular exercise might help normalize blood glucose levels. However, sometimes, insulin may be required to keep your blood glucose levels in normal range (1). In this post, MomJunction gives you the safety profile of insulin tablets and injections during pregnancy.

When will insulin be required for pregnant women?

2020-08-29 23 November 2020. During pregnancy some expecting women may not be able to cope with the increased insulin requirement. This may result in a need to take insulin during pregnancy. For first-time mothers and especially women who did not have diabetes before pregnancy, this can be a stressful and frightening situation.

Where should a pregnant woman inject insulin?

Pregnant women should inject insulin in areas rich in fat mass such as the abdomen or sides of the thigh as insulin is best absorbed in these areas. This is less painful and helps absorb the insulin faster. Some injection sites/areas are:

How does insulin affect a fetus?

Insulin is a very safe choice in pregnancy as it does not cross the placenta and reach the fetus.

How to rotate sites for insulin shots?

Rotate sites by selecting an area in a way that there is atleast a one finger breadth between two insulin shots. If you notice a bump or nodule at the injection site, it is better to avoid the site as the insulin absorption could be erroneous.

How to avoid insulin injections?

Avoid using an area that you are likely to exercise as that could cause insulin to be disposed much faster.

How long does insulin last?

Long acting insulin which works after 2-3 hours but lasts for 24 hours. “I had many misconceptions about insulin during pregnancy which were patiently cleared by the diabetologist and educator,” remembers Priya.

Can insulin cause hypoglycemia?

The main insulin side effect during pregnancy is that it could cause low blood sugar levels (hypoglycemia) in case you missed/delayed a meal or injected excess insulin. “My doctor alerted me of the signs to watch out for and how to treat low blood sugar during pregnancy,” says Priya.

What happens if you have insufficient insulin in your fetus?

Insufficient maternal insulin secretion or action may result in increased insulin secretion by the fetus, increased fetal growth and fat deposition, and neonatal hypoglycemia. Maternal diabetes mellitus may be complicated by fetal macrosomia, relatively large-for-age offspring, and predisposes the offspring to diabetes.

Is hyperglycemia a factor in diabetes?

A significantly higher percentage of major malformations has been associated with elevated hemoglobin A1C levels, suggesting that hyperglycemia, or poor control of diabetes, and not insulin, is the causal factor. Diabetes portends risk during pregnancy. In a nationwide, four-year retrospective review of 491 insulin-dependent diabetic pregnancies in ...

Does insulin cross the placenta?

Insulin crosses the human placenta in small amounts. In one study, in which 28 cord-serum samples from pregnant women who were receiving animal insulin were evaluated, animal insulin constituted 27% of the total insulin measured from cord serum.#N#The rate of congenital malformations appears to be associated with the severity of maternal diabetes rather than the use of insulin, a naturally-occurring hormone. The question of whether exogenous insulin itself or insulin-induced hypoglycemia causes the significantly elevated incidence of congenital malformations in infants of diabetic mothers has been evaluated. A significantly higher percentage of major malformations has been associated with elevated hemoglobin A1C levels, suggesting that hyperglycemia, or poor control of diabetes, and not insulin, is the causal factor.#N#Diabetes portends risk during pregnancy. In a nationwide, four-year retrospective review of 491 insulin-dependent diabetic pregnancies in Sweden, the rates of pregnancy-induced hypertension or preeclampsia, premature delivery, Cesarean section, large-for-age offspring, and perinatal mortality in the diabetic group were more than four times higher than normal. Insufficient maternal insulin secretion or action may result in increased insulin secretion by the fetus, increased fetal growth and fat deposition, and neonatal hypoglycemia. Maternal diabetes mellitus may be complicated by fetal macrosomia, relatively large-for-age offspring, and predisposes the offspring to diabetes. Gestational age appears to be a determinant of neonatal morbidity. Many experts recommend delivery at 38 weeks, if possible.#N#There is an impaired counterregulatory response to hypoglycemia in pregnant diabetic women. Relative to nonpregnant diabetic women or normal controls, this group demonstrates suppressed basal growth hormone during late pregnancy and blunted or decreased glucagon levels during hypoglycemia. Fortunately, the fetus appears to be protected from maternal hypoglycemia. Neither fetal death nor congenital malformations have been associated with insulin-induced hypoglycemic reactions.#N#Insulin use may significantly increase in pregnant women with diabetes mellitus type I during pregnancy. In one study, the average increase was 52 units per day, and was significantly related to maternal weight gain between 20 and 29 weeks and maternal weight at presentation, and was inversely related to the duration of diabetes. A small number of pregnant patients required less insulin.

Can you give insulin to a pregnant woman?

Because of the strong association between diabetes or hyperglycemia and perinatal morbidity and multiple congenital malformations, most experts recommend strict control of maternal plasma glucose with the use of insulin during pregnancy. Insulin should only be given during pregnancy when need has been clearly established.

Is insulin used during pregnancy?

A small number of pregnant patients required less insulin. Insulin has been assigned to pregnancy category B. It is the drug of choice for the treatment of diabetes during pregnancy. Data from human pregnancy have revealed an increased incidence of teratogenicity associated with diabetes mellitus; the association with the use ...

Can a fetus die from hypoglycemia?

Fortunately, the fetus appears to be protected from maternal hypoglycemia. Neither fetal death nor congenital malformations have been associated with insulin-induced hypoglycemic reactions. Insulin use may significantly increase in pregnant women with diabetes mellitus type I during pregnancy.

Does insulin dependent diabetes mellitus cause lactose to be lower?

Limited data reveal that the milk of women with insulin dependent diabetes mellitus (IDDM) has significantly lower lactose and higher total nitrogen relative to nondiabetic women. The infants of women with IDDM in this study had significantly less milk intake. The data indicate delayed lactogenesis for women with IDDM. The differences in milk composition of women with IDDM do not preclude them from breast-feeding.

Short-Acting Insulin and Rapid-Acting Insulin Analogs

Regular (U-100) insulin is identical to human insulin and is synthesized in Escherichia coli bacteria. It is used as a mealtime insulin to cover carbohydrate loads. Its time to onset of action is ∼30 minutes but can range from 10–75 minutes. The maximum effect is in 3 hours (range 20 minutes to 7 hours), and the effect terminates at ∼8 hours.

Intermediate Insulin and Long-Acting Insulin Analogs

Insulin isophane (NPH) is a U-100, intermediate-acting insulin. It is produced in E. coli. It is identical to human insulin and is in a suspension. Its onset of action is 1–2 hours, with an average peak of 4 hours (range: 4–8 hours). Duration of action is 10–20 hours.

Novel Insulin Delivery

Human insulin inhalation powder was approved by the FDA in 2014. Inhaled human insulin is produced in E. coli and is adsorbed onto fumaryl diketopiperazine and polysorbate 80 carrier particles. Inhalation powder is equivalent unit-for-unit to insulin lispro. Its onset is 12–15 minutes, and its time to peak is ∼57 minutes. Duration is ∼2 hours.

Insulin Dosing in Pregnancy

Insulin has long been considered the standard of care to attain optimal glucose control in pregnancy, although multiple methods are available to initiate insulin. Weight-based dosing, weight plus gestational age–based dosing, and even a “one-dose-for-all” type of dosing have been used ( Table 2 ).

Insulin Safety in Pregnancy

Most insulins carry an FDA Pregnancy Category ( 29 ). However, in 2015, the FDA ruled that the lettering system will no longer be used. A summary of available insulins and current associated pregnancy categories illustrates these changes ( Table 3 ).

Conclusion

Insulin therapy remains the standard of care for type 1 diabetes, type 2 diabetes, and uncontrolled GDM during pregnancy. Regular insulin, insulin aspart, insulin lispro, and NPH have the most human pregnancy data. Insulin detemir is quickly gaining data and provides an additional option for basal coverage.

Duality of Interest

No potential conflicts of interest relevant to this article were reported.

How many pregnant women in Australia have diabetes?

One in twenty pregnant women in Australia is affected by diabetes. Although the disease can cause serious complications for mothers and babies, good planning and comprehensive antenatal care can keep you and your baby healthy. By Joanna Egan. Diabetes is a chronic condition characterised by the body's inability to control glucose levels in the blood. Glucose is a simple sugar found in foods such as breads, cereals, fruit, starchy vegetables, legumes, dairy products and sweets. A hormone produced by the pancreas, called insulin, converts this glucose into energy that is used to fuel the body. When a person has diabetes, they either don't produce enough insulin or are unable to use insulin effectively. This causes glucose to build up in their bloodstream. There are several types of diabetes: Type 1: People with type 1 diabetes don't produce insulin. As a result, they need to monitor their blood glucose levels carefully and require regular insulin injections (up to four times a day). Generally, type 1 diabetes arises in children and young adults, but it can occur at any age. Type 2: This is the most common form of diabetes. Some people have a genetic predisposition to developing the disease but often, it is caused by lifestyle factors such as high blood pressure, obesity, insufficient exercise and poor diet. People with type 2 diabetes produce insulin, but either don't produce enough or are unable to use it effectively. Generally, it is initially managed with healthy eating and regular physical activity, but as the condition progresses, glucose-lowering tablets and/or insulin injections may be prescribed. Gestational diabetes: This form of diabetes develops, or is first diagnosed, during pregnancy. It usually appears late in the second trimester and resolves after childbir Continue reading >>

How many people will have diabetes by 2050?

About 5% of all diagnosed diabetes is type 1 diabetes, and 90–95% is type 2 diabetes. It is projected that, by 2050, one in three people will have some type of diabetes. An estimated 5,000 new cases of type 2 diabetes will be diagnosed annually in American children <20 years of age (2). Gestational diabetes mellitus (GDM) could affect up to 8.7% of all pregnancies in the United States (3). The Centers for Disease Control and Prevention reports that these numbers are still on the rise (2). As the age of diabetes diagnosis decreases in U.S. youth, the prevalence of pregestational diabetes is likely to increase in the pregnant population. Maternal diabetes causes complications in the embryo/fetus that start in the uterus, are present immediately after birth, and could potentially last a lifetime. Women with type 1 diabetes or type 2 diabetes diagnosed before or during the first trimester of pregnancy are at the greatest risk for fetal congenital anomalies and spontaneous abortions. This risk is associated with both frequent and severe hyperglycemia before conception and during organogenesis (5–8 weeks after the last menstrual period) (4,5). The more severe the maternal hyperglycemia, the greater is the risk for fetal abnormalities. Structural anomalies are a common result, with ∼37% of these affecting the cardiovascular system, 20% affecting the central nervous system, and 14% affecting the urogenital system (6). GDM develops and is diagnosed later in pregnancy, at 24–28 weeks’ gestation, when impaired glucose tolerance is detectable. Therefore, women with GDM are most likely euglycemic during organogenesis and have a decreased risk Continue reading >>

Can diabetes cause complications during pregnancy?

INTRODUCTION Before insulin became available in 1922, women with diabetes mellitus were at very high risk of complications of pregnancy. Today, most women with diabetes can have a safe pregnancy and delivery, similar to that of women without diabetes. This improvement is largely due to good blood glucose (sugar) control, which requires adherence to diet, frequent daily blood glucose monitoring, and frequent insulin adjustment. This topic review discusses care of women with type 1 or 2 diabetes during pregnancy, as well as fetal and newborn issues. It does not address gestational diabetes, which is diabetes that is first diagnosed during pregnancy. (See "Patient education: Gestational diabetes mellitus (Beyond the Basics)".) IMPORTANCE OF BLOOD GLUCOSE CONTROL Glucose in the mother's blood crosses the placenta to provide energy for the baby; thus, high blood glucose levels in the mother lead to high blood glucose levels in the developing baby as well. High blood glucose levels can cause several problems: Early in pregnancy, high glucose levels increase the risk of miscarriage and birth defects. These risks are highest when glycated hemoglobin (hemoglobin A1C or A1C) is >8 percent or the average blood glucose is >180 mg/dL (10 mmol/L). In the last half of pregnancy and near delivery, high blood glucose levels can cause the baby's size and weight to be larger than average and increase the risk of complications during and after delivery (see 'Newborn issues' below). In particular, women with large babies are more likely to have difficulty with a vaginal birth and have a higher chance of needing a cesarean delivery. In the last half of pregnancy, women with diabetes are more prone to developing pregnancy-induced hypertension (preeclampsia) and an excessive amount of amniotic Continue reading >>

Is Insulin Safe For Pregnant Or Breastfeeding Women?

However, they have not had enough testing in pregnant women to prove that they are safe, so there may be some risk. Other, often newer, forms of insulin are classified as category C drugs, which means they have been shown to cause some harm in animal studies and may not be safe for use during pregnancy. Insulin is widely considered safe for women who are breastfeeding. However, it is always best to ask your doctor about the possible risks if you are breastfeeding, and about how breastfeeding will affect the amount and type of insulin you need. Continue reading >>

How long does insulin last?

Your doctor will probably prescribe this type, along with one that lasts about 12 hours or overnight.

What to watch for after pregnancy?

What to Watch For. After Your Pregnancy. Other Medicines. Eating healthy foods and getting plenty of exercise may be all you need to control your blood sugar levels during your pregnancy. But when that's not enough, you may need to take insulin, too. Insulin is a hormone that helps your cells take in and use glucose.

What are the symptoms of insulin resistance?

You're more likely to have this if you skip a meal or use too much insulin. Be sure you know the warning signs: dizziness, sweating, shaking, and blurry vision. The best treatment is a quick- sugar food like raisins, honey, or glucose tablets or gel.

Can insulin injections cause lumps?

You might get sore and have hard lumps where you inject the insulin. To prevent this, try not to give yourself the shot in the same place every time.

Does the pancreas make insulin?

Your pancreas makes insulin, but the kind you take is made in a lab. Your doctor may prescribe it when your body doesn't make enough on its own to keep your blood sugar levels in a normal range. That will help prevent problems for you and your baby.

Can you stop taking insulin while pregnant?

After Your Pregnancy. The hospital will check your blood sugar before you leave. If it's normal, you can stop taking insulin. But because you've had gestational diabetes, you're more likely to get type 2 diabetes later.

How to manage diabetes during pregnancy?

Much of the business of managing your diabetes in pregnancy involves checking your blood glucose levels and adjusting your treatment regime accordingly. For some women with diabetes, the need to change treatment during pregnancy can be frustrating, especially if you have maintained good control and are settled into the treatment you were using. Learning to inject or use a pump can feel like just another thing to do. But try to stay positive. Focus on the fact that this technology is available to help you keep your glucose at safe levels for your baby. Each day that passes takes you one day closer to your baby being born. After your baby is born, your diabetes will probably return to its original patterns. 'I think it is one of the hardest things I have had to do, both times, but you just kind of keep going. It’s like running a marathon. You know that you will eventually get to the end, and it does seem really tough at the beginning but you just get through it.' Prisha, mum of two If you were already using insulin Your team may change your doses or suggest that you try a regimen that is more effective. You may be using a syringe, a pen or a pump. If you are new to insulin Insulin only works if it is injected – so if you need to take it, then this will mean injecting. If you need to start giving yourself insulin injections, your diabetes team will show you how to inject yourself, what times you need to do it, how to keep your insulin and where to put the used needles. Many people do not like the idea of injecting, but try not to worry – injecting insulin is not like injections you may have had in the past. You will be using either a syringe or a pen, with a very fine needle. These are not usually painful, though they may feel worse if you are anxious. Once people le Continue reading >>

How to control blood sugar during pregnancy?

Eating healthy foods and getting plenty of exercise may be all you need to control your blood sugar levels during your pregnancy. But when that's not enough, you may need to take insulin, too. Insulin is a hormone that helps your cells take in and use glucose. Your pancreas makes insulin, but the kind you take is made in a lab. Your doctor may prescribe it when your body doesn't make enough on its own to keep your blood sugar levels in a normal range. That will help prevent problems for you and your baby. Insulin doesn't cross the placenta, which means it can't get to your baby, so it's safe to use as prescribed. Taking Insulin You inject it under your skin with a syringe or insulin pen. You can't take insulin as a pill or drink it. How much you'll need and how often you'll need it will probably change during your pregnancy. Some kinds of insulin work in just a few minutes; others work more slowly but last longer. You take fast-acting insulin with a meal, so it goes to work right away to help your body use the glucose from the food you ate. Your doctor will probably prescribe this type, along with one that lasts about 12 hours or overnight. Longer-acting (24-hour) insulin hasn't been studied with pregnant women. What to Watch For You might get sore and have hard lumps where you inject the insulin. To prevent this, try not to give yourself the shot in the same place every time. Insulin can also cause low blood sugar (hypoglycemia) when there's not enough glucose in your blood for your body to work right. You're more likely to have this if you skip a meal or use too much insulin. Be sure you know the warning signs: dizziness, sweating, shaking, and blurry vision. The best treatment is a quick-sugar food like raisins, honey, or glucose tablets or gel. Low blood sugar can b Continue reading >>

Are Insulin Injections Safe During Pregnancy?

Her gynaecologist has advised her insulin injections. Is insulin the only answer to gestational diabetes? Is it safe to take insulin during pregnancy? How to bring down the glucose level? A:Your wife has developed gestational diabetes, which is specific during pregnancy and most often disappears after delivery but she will remain a high risk for diabetes during her life. Although there are few studies which shows good safety of oral medications specially glibenclamide but no large studies available on this issue. Therefore it is best and in interest of both mother and child to use insulin during pregnancy. Go ahead and get her started on diet and insulin. Please note that there needs to be a tighter control of blood glucose levels during pregnancy. Continue reading >>

How many people will have diabetes by 2050?

About 5% of all diagnosed diabetes is type 1 diabetes, and 90–95% is type 2 diabetes. It is projected that, by 2050, one in three people will have some type of diabetes. An estimated 5,000 new cases of type 2 diabetes will be diagnosed annually in American children <20 years of age (2). Gestational diabetes mellitus (GDM) could affect up to 8.7% of all pregnancies in the United States (3). The Centers for Disease Control and Prevention reports that these numbers are still on the rise (2). As the age of diabetes diagnosis decreases in U.S. youth, the prevalence of pregestational diabetes is likely to increase in the pregnant population. Maternal diabetes causes complications in the embryo/fetus that start in the uterus, are present immediately after birth, and could potentially last a lifetime. Women with type 1 diabetes or type 2 diabetes diagnosed before or during the first trimester of pregnancy are at the greatest risk for fetal congenital anomalies and spontaneous abortions. This risk is associated with both frequent and severe hyperglycemia before conception and during organogenesis (5–8 weeks after the last menstrual period) (4,5). The more severe the maternal hyperglycemia, the greater is the risk for fetal abnormalities. Structural anomalies are a common result, with ∼37% of these affecting the cardiovascular system, 20% affecting the central nervous system, and 14% affecting the urogenital system (6). GDM develops and is diagnosed later in pregnancy, at 24–28 weeks’ gestation, when impaired glucose tolerance is detectable. Therefore, women with GDM are most likely euglycemic during organogenesis and have a decreased risk Continue reading >>

How does diabetes affect pregnancy?

Diabetes can cause problems during pregnancy for women and their developing babies. Poor control of diabetes during pregnancy increases the chances for birth defects and other problems for the pregnancy. It can also cause serious complications for the woman. Proper health care before and during pregnancy can help prevent birth defects and other health problems. About Diabetes Diabetes is a condition in which the body cannot use the sugars and starches (carbohydrates) it takes in as food to make energy. The body either makes no insulin or too little insulin or cannot use the insulin it makes to change those sugars and starches into energy. As a result, extra sugar builds up in the blood. The three most common types of diabetes are: Type 1 The pancreas makes no insulin or so little insulin that the body can’t use blood sugar for energy. Type 1 diabetes must be controlled with daily insulin. Type 2 The body either makes too little insulin or can’t use the insulin it makes to use blood sugar for energy. Sometimes type 2 diabetes can be controlled through eating a proper diet and exercising regularly. Many people with type 2 diabetes have to take diabetes pills, insulin, or both. Gestational This is a type of diabetes that is first seen in a pregnant woman who did not have diabetes before she was pregnant. Often gestational diabetes can be controlled through eating a healthy diet and exercising regularly. Sometimes a woman with gestational diabetes must also take insulin. For most women with gestational diabetes, the diabetes goes away soon after delivery. When it does not go away, the diabetes is called type 2 diabetes. Even if the diabetes does go away after the baby is born, half of all women who had gestational diabetes develop type 2 diabetes later. It’s important Continue reading >>

Does insulin affect pregnancy?

Insulin Pregnancy Warnings Insulin crosses the human placenta in small amounts. In one study, in which 28 cord-serum samples from pregnant women who were receiving animal insulin were evaluated, animal insulin constituted 27% of the total insulin measured from cord serum. The rate of congenital malformations appears to be associated with the severity of maternal diabetes rather than the use of insulin, a naturally-occurring hormone. The question of whether exogenous insulin itself or insulin-induced hypoglycemia causes the significantly elevated incidence of congenital malformations in infants of diabetic mothers has been evaluated. A significantly higher percentage of major malformations has been associated with elevated hemoglobin A1C levels, suggesting that hyperglycemia, or poor control of diabetes, and not insulin, is the causal factor. Diabetes portends risk during pregnancy. In a nationwide, four-year retrospective review of 491 insulin-dependent diabetic pregnancies in Sweden, the rates of pregnancy-induced hypertension or preeclampsia, premature delivery, Cesarean section, large-for-age offspring, and perinatal mortality in the diabetic group were more than four times higher than normal. Insufficient maternal insulin secretion or action may result in increased insulin secretion by the fetus, increased fetal growth and fat deposition, and neonatal hypoglycemia. Maternal diabetes mellitus may be complicated by fetal macrosomia, relatively large-for-age offspring, and predisposes the offspring to diabetes. Gestational age appears to be a determinant of neonatal morbidity. Many experts recommend delivery at 38 weeks, if possible. There is an impaired counterregulatory response to hypoglycemia in pregnant diabetic women. Relative to nonpregnant diabetic women or nor Continue reading >>

Has Anyone Refused Insulin For Gestational Diabetes?

Diabetes Forum The Global Diabetes Community Find support, ask questions and share your experiences. Join the community Has anyone refused insulin for gestational diabetes? After not having diabetes pre-pregnancy, I was diagnosed with gestational diabetes on Tuesday and tried to control by diet, but most of the readings in the two days I have tested blood glucose were higher than the NICE guidelines (over 7.7 mmol/l one hour after meals and over 5.8mmol/l before breakfast): Now considering that according to the NHS the normal type 2 diabetic acceptable readings are that "a normal blood glucose level is between 4.0-6.0 mmol/l before meals (preprandial), and less than 10.0 mmol/l two hours after meals (postprandial)": I am under the normal type 2 limits, but over the NICE guidelines. Also notice that the NICE guidelines say ONE hour after meals and the normal guidelines say TWO hours after meals. This seems grossly unfair and I have not been able to find any reason why the goalposts have been moved, either on the interenet or by asking people. The diabetic nurse couldn't answer the question either and said "but these are national guidelines" (for anyone who has seen the film This is Spinal Tap, she may as well have said "these go up to 11 I'm not doing anything "wrong" with my diet as I confirmed with the dietician today, so the diabetic nurse/midwife wanted me to go on insulin. I asked if they did tablets and they said no, only insulin. This to me seems very extreme. The nurse got out the insulin pen to show me, I saw the needle and completely freaked out. I burst into uncontrollable sobbing and my eyes glazed over when she asked me if I was going to try it in my stomach or my thigh. When I didn't respond, she offered to inject it into my stomach or thigh. I still wasn' Continue reading >>

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8.Is It Safe To Use Insulin During Pregnancy?

Url:https://diabetestalk.net/insulin/is-it-safe-to-use-insulin-during-pregnancy

19 hours ago Insulin doesn't cross the placenta, which means it can't get to your baby, so it's safe to use as prescribed. Taking Insulin You inject it under your skin with a syringe or insulin pen .

9.Insulin for Gestational Diabetes: Is It Safe For Your Baby?

Url:https://www.webmd.com/diabetes/gestational-diabetes-insulin-safe

18 hours ago  · Effects on Pregnancy: Insulin is the drug of choice for treatment of diabetes during pregnancy. Insulin does not cross the placenta, and it does not go to the fetus. …

10.Is It Safe To Take Insulin During Pregnancy?

Url:https://diabetestalk.net/insulin/is-it-safe-to-take-insulin-during-pregnancy

35 hours ago  · Adjust the units and dosage in the pen and push the injection button. The pen is ready to use when you notice the insulin moving outwards. Clean the injection site with an …

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