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is nifedipine and procardia the same

by Jayson Morissette DDS Published 2 years ago Updated 2 years ago
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Nifedipine immediate-release capsules are available as the brand-name drug Procardia. The capsules are used to treat angina (chest pain). The tablets are used to treat either high blood pressure or angina.

Precautions

Nifedipine tablets are an extended-release form of the drug. Nifedipine is also available in immediate-release oral capsules. The capsules are available as the brand-name drug Procardia. They are also available in a generic drug.

What is the difference between Nifedipine tablets and capsules?

History. This study was a meta-analysis, and demonstrated harm mainly in short-acting forms of nifedipine (that could cause large fluctations in blood pressure) and at high doses of 80 mg a day and more.

Does nifedipine cause high blood pressure?

By dilating coronary arteries, nifedipine increases the flow of blood to the heart. This treats and prevents angina which occurs when the flow of blood to the heart is not adequate to supply the heart with enough oxygen necessary to pump blood.

How does nifedipine work to treat angina?

Other drugs in the same class as nifedipine include: 1 amlodipine ( Norvasc ), 2 diltiazem ( Cardizem LA, Tiazac ), 3 felodipine ( Plendil ), 4 isradipine ( Dynacirc ), 5 nicardipine ( Cardene ), 6 ... (2 more items)

What are other drugs in the same class as nifedipine?

What are the side effects of nifedipine (Procardia XL)?

How much does nifedipine (Procardia XL) cost?

What is the generic name for Procardia XL?

How long does it take for Procardia XL to work?

How does nifedipine work?

How many milligrams of a sulfate can you take?

How to store a syringe?

See 4 more

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What is the difference between Procardia and nifedipine?

The primary difference between the drugs is the manner in which they release nifedipine. Procardia XL leaches nifedipine through an osmotic pump delivery system.

What is a good substitute for nifedipine?

Nisoldipine: a replacement therapy for nifedipine in the treatment of severe hypertension.

Why is nifedipine no longer used?

Nifedipine, a dihydropyridine calcium channel blocker, was once one of the most widely used medications for hypertension, but safety and tolerability concerns along with the introduction of new classes of antihypertensive medications and an increasing pool of data showing mortality benefit of other classes caused ...

Are there different types of nifedipine?

Nifedipine is available under the following different brand names: Procardia, Procardia XL, Adalat CC, Nifedical XL, Adalat, Afeditab CR, and Nifediac CC.

What is the first drug of choice for hypertension?

The first choice is usually a thiazide diuretic.

What foods should be avoided when taking nifedipine?

Grapefruits and grapefruit juice may increase the effects of nifedipine by increasing the amount of this medicine in your body. You should not eat grapefruit or drink grapefruit juice while you taking this medicine.

When should you not take nifedipine?

For people with severe heart disease: There have been rare reports of worsening chest pain and heart attack in people who have severe heart disease. Nifedipine capsules (Procardia) should not be taken within the first week or two after a heart attack.

What are the most common side effects of nifedipine?

Side EffectsBloating or swelling of the face, arms, hands, lower legs, or feet.difficult or labored breathing.dizziness or lightheadedness.fast, irregular, pounding, or racing heartbeat or pulse.feeling of warmth.headache.muscle cramps.shakiness in the legs, arms, hands, or feet.More items...•

What is the best time of day to take nifedipine?

You can take nifedipine at any time of day, but try to make sure it's around the same time (or times) every day. Swallow the capsules or tablets whole with a drink of water. Do not break, crush, chew or open up the capsules unless your doctor or pharmacist has said you can.

What is the generic name for nifedipine?

Nifedipine (Procardia XL) is a calcium channel blocker (CCB). It mainly works by relaxing your blood vessels, which lowers blood pressure and gets more oxygen to your heart to help with chest pain.

What are the negative effects of nifedipine?

Dizziness, flushing, weakness, swelling ankles/feet, constipation, and headache may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. To reduce dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.

Is 60 mg of nifedipine a lot?

For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day.

Which is better nifedipine or amlodipine?

In conclusion, amlodipine given once daily is at least as effective as nifedipine tablets given twice daily in patients with essential hypertension.

Can amlodipine replace nifedipine?

While these medications are both effective, they are not without limitations. Amlodipine is a medication in the same class as nifedipine ER. It is a first-line antihypertensive in the general population. It tends to have less side effects than nifedipine ER.

Is there a generic drug for nifedipine?

Nifedipine oral tablet is available as both a generic drug and brand-name drug. Brand name: Procardia XL. Nifedipine tablets are an extended-release form of the drug. Nifedipine is also available in immediate-release oral capsules.

Is nifedipine a good blood pressure medicine?

Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly.

What is nifedipine (Procardia XL) used for?

Nifedipine (Procardia XL) is FDA-approved for the treatment of chest pain (angina) and high blood pressure (hypertension).

How quickly does nifedipine work?

Nifedipine (Procardia XL) tablets have extended-release properties, so they absorb in the body slowly over time and can take up to 6 hours to reach...

Why is the immediate-release capsule form of nifedipine not used as often anymore?

The immediate-release capsule form of nifedipine (Procardia) isn't used as much these days, because it works very quickly and can drop your blood p...

Is nifedipine (Procardia XL) bad for the kidneys?

Nifedipine (Procardia XL) is usually not harmful to the kidneys. In fact, it can actually be good for the kidneys, especially if you are using it t...

Why is nifedipine sometimes used in pregnancy?

Nifedipine is one of the first-choice medications for treating high blood pressure in pregnant women. It works well to lower high blood pressure (w...

Nifedical XL 30mg vs. Nifedipine ER Osmotic 90? - Drugs.com

I originally was prescribed Nifedical XL 30mg it seemed to work. When I picked up my prescription renewal I failed to notice the different name (Nifedipine ER) but when i began taking it a few days later i noticed the size, shape, and possibly dosage difference.

Nifedipine ER: Is it same as nifedipine xl - Medications.com

I am currently taking Nifedipine XL 30 mg. Is this the same as Nifedipine ER. If not, what's the difference?

Nifedipine Side Effects: Common, Severe, Long Term - Drugs.com

Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex (updated 12 Oct 2022), Cerner Multum™ (updated 25 Oct 2022), ASHP (updated 12 Oct 2022 ...

Comparison of two formulations of nifedipine during 24-hour ... - PubMed

Study objective: To determine if one commercial extended-release formulation of nifedipine (Adalat CC) is as effective as another (procardia XL) in controlling blood pressure over 24 hours. Design: Open-label, randomized, crossover study. Setting: University-affiliated family medicine clinic. Patients: Fifteen patients with stage 1-4 primary hypertension.

Nifedipine ER Oral: Uses, Side Effects, Interactions, Pictures ... - WebMD

Find patient medical information for Nifedipine ER oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.

Why is nifedipine high in blood?

If you have liver disease, your body may have trouble clearing nifedipine from your blood. This may cause the amount of nifedipine in your blood to be too high. Your doctor may adjust your dose to keep the amount of nifedipine in your body at a safe level.

Why is nifedipine used for chest pain?

Why it’s used. Nifedipine is used to lower blood pressure in people with hypertension . It’s also used to treat vasospastic angina (chest pain due to a spasm in arteries around the heart) or chronic stable angina (chest pain that occurs with activity or stress).

How does nifedipine work?

A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions. Calcium channel blockers help lower blood pressure by relaxing the blood vessels throughout your body.

What is the name of the drug that is extended release?

Brand names: Adalat CC, Afeditab CR, and Procardia XL. Nifedipine tablets are an extended-release form of the drug. Nifedipine is also available in immediate-release oral capsules. The capsules are available as the brand-name drug Procardia. They are also available in a generic drug.

How do calcium channel blockers help with angina?

Calcium channel blockers help to prevent angina in two ways. First, they lower pressure in the coronary arteries ( the arteries that supply blood to your heart). As a result, your heart receives more blood and oxygen. Second, they help prevent spasm of the coronary arteries.

Why do older people have kidney problems?

The kidneys of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time . This increases your risk of side effects. Your doctor may start you on a lowered dose or a different medication schedule. This can help keep levels of this drug from building up too much in your body.

Can you take rifampin and nifedipine together?

This could make nifedipine less effective. You shouldn’t take rifampin and nifedipine together.

What is the best treatment for high blood pressure?

High blood pressure. The approved uses are for the long-term treatment of hypertension and angina pectoris. In hypertension, recent clinical guidelines generally favour diuretics and ACE inhibitors, although calcium channel antagonists, along with thiazide diuretics, are still favoured as primary treatment for patients over 55 and black patients.

What are the side effects of taking nifedipine?

Common side effects include lightheadedness, headache, feeling tired, leg swelling, cough, and shortness of breath.

When was nifedipine first used?

Nifedipine was patented in 1967, and approved for use in the United States in 1981. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication. In 2018, it was the 121st most commonly prescribed medication in the United States, with more than 5 million prescriptions.

Can Prinzmetal be used in pregnancy?

It is one of the treatments of choice for Prinzmetal angina. It may be used to treat severe high blood pressure in pregnancy. Its use in preterm labor may allow more time for steroids to improve the baby's lung function and provide time for transfer of the mother to a well qualified medical facility before delivery.

Is nifedipine a calcium channel blocker?

Nifedipine is a calcium channel blocker . Although nifedipine and other dihydropyridines are commonly regarded as specific to the L-type calcium channel, they also possess nonspecific activity towards other voltage-dependent calcium channels.

Is nifedipine toxic to humans?

A number of persons have developed toxicity due to acute overdosage with nifedipine, either accidentally or intentionally, and via either oral or parenteral administration. The adverse effects include lethargy, bradycardia, marked hypotension and loss of consciousness. The drug may be quantified in blood or plasma to confirm a diagnosis of poisoning, or to assist in a medicolegal investigation following death. Analytical methods usually involve gas or liquid chromatography and specimen concentrations are usually in the 100-1000 μg/L range. [1]

Can you take nifedipine on an empty stomach?

Extended release formulations of nifedipine should be taken on an empty stomach, and patients are warned not to consume anything containing grapefruit or grapefruit juice, as they raise blood nifedipine levels. There are several possible mechanisms, including the inhibition of CYP3A4 -mediated metabolism.

What is Nifedipine?

Nifedipine has active ingredients of nifedipine. It is often used in high blood pressure. eHealthMe is studying from 42,601 Nifedipine users for its effectiveness, alternative drugs and more.

What is Hydrochlorothiazide?

Hydrochlorothiazide has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 148,324 Hydrochlorothiazide users for its effectiveness, alternative drugs and more.

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

How the study uses the data?

The study uses data from the FDA. It is based on nifedipine and hydrochlorothiazide (the active ingredients of Nifedipine and Hydrochlorothiazide, respectively), and Nifedipine and Hydrochlorothiazide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature.

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

Can you drink alcohol while taking diltiazem?

Some brands of Diltiazem have to be taken with food, so listen carefully for instructions from your doctor or pharmacist. Not a good medication for you if you drink alcohol. Calcium channel blockers can cause swelling in your limbs. If this happens for you, it probably won't get better over time, so talk to your doctor about alternatives ...

Does calcium channel blocker cause chest pain?

Prevents heart-related chest pain (angina) if you take it regularly. Treats certain abnormal heart rhythms. Downsides. Calcium channel blockers can cause swelling in your limbs. If this happens for you, it probably won't get better over time, so talk to your doctor about alternatives if it bothers you. Women are more likely to have side effects ...

Does calcium channel blocker lower blood pressure?

Treats certain abnormal heart rhythms. A first-choice blood pressure treatment for many people. Calcium channel blockers work especially well for African Americans to lower blood pressure.

Does diltiazem lower blood pressure?

Lowers blood pressure and controls heart rate. Diltiazem works well to lower blood pressure and prevent chest pain, but you have to be okay with avoiding alcohol. You can't miss doses, and you might get persistent swelling. Lowers blood pressure and controls heart rate.

Does nifedipine cause heart attacks?

Stopping Nifedipine suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke. Not a good medication for you if you love grapefruit. It can make Nifedipine have a stronger effect on your blood pressure. ADVERTISEMENT.

Can you take nifedipine with grapefruit?

Nifedipine works well to lower blood pressure and prevent chest pain, but you have to be okay with avoiding grapefruit. You can't miss doses, and you might get persistent swelling.

Is diltiazem bad for women?

Women are more likely to have side effects (especially swelling) from Diltiazem than men.

Can amlodipine cause edema?

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions. Amlodipine may be used for the treatment of angina or to lower blood pressure but can cause edema in the feet. Prescribed for Raynaud's Syndrome, High Blood Pressure, Angina, Heart Failure, Coronary...

What is the half life of a drug?

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

Is nifedipine used for high blood pressure?

Prescribed for Raynaud's Syndrome, High Blood Pressure, Angina, Heart Failure, Coronary... Nifedipine is used in the treatment of vasospastic angina and occasionally for chronic unstable angina as an add-on to other treatments. Nifedipine should not be used to rapidly drop blood pressure...

What is nifedipine used for?

Nifedipine belongs to a class of medications called calcium channel blockers ( CCBs) that are used to treat angina ( heart pain ), high blood pressure, and abnormal heart rhythms.

How does verapamil work?

Like other CCBs, nifedipine works by blocking the flow of calcium into the muscle cells surrounding the arteries that supply blood to the heart (coronary arteries) as well as other arteries of the body.

What are the side effects of nifedipine?

Side effects of nifedipine are generally mild, and reversible. Most side effects are expected consequences of the dilation of the arteries. The most common side effects include: Headache. Dizziness.

What is a non-FDA approved use for a fissure?

Non-FDA approved uses include: anal fissures (applied to the fissures), prevention of migraine headaches in adults,

What is a syringe used for?

It is used in the treatment of high blood pressure, to treat abnormally fast heart rhythms such as atrial fibrillation, and in the prevention of episodes of rapid heart rhythm originating from the atria of the heart. It also is used to dilate blood vessels that go into spasm such as those causing Raynaud's phenomenon, ...

When was nifedipine approved?

The FDA approved nifedipine in December 1981.

What is anal fissure?

anal fissures (applied to the fissures), prevention of migraine headaches in adults, ureteral stones (as secondary therapy) and. wound healing (applied to the skin).

What are the side effects of nifedipine (Procardia XL)?

With any medication, there are risks and benefits. Even if the medication is working, you may experience some unwanted side effects.

How much does nifedipine (Procardia XL) cost?

Nifedipine (Procardia XL) is available as a generic medication and may be significantly cheaper compared to the brand version. Unless there is a specific reason you need the brand, the generic medication will be a better value. For even more savings, use a GoodRx coupon and pay just a fraction of the retail price.

What is the generic name for Procardia XL?

Generic Procardia XL. NIFEDIPINE is a calcium channel blocker. It relaxes your blood vessels and decreases the amount of work the heart has to do. It treats high blood pressure and/or prevents chest pain (also called angina ).

How long does it take for Procardia XL to work?

It takes 1 to 2 weeks to see the full effects of nifedipine (Procardia XL). Let your provider know if you don't see an improvement in your chest pain symptoms or blood pressure after a week.

How does nifedipine work?

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

How many milligrams of a sulfate can you take?

Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.

How to store a syringe?

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed.

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Overview

This medication is used to prevent certain types of chest pain (angina).

May Treat: Hypertension · Anginal pain from vasospastic angina · Anginal pain in coronary artery disease

Brand Names: Procardia · Adalat CC · Procardia XL · Nifediac CC · Nifedical XL and more

Drug Class: Calcium Channel Blockers - Dihydropyridines

Availability: Prescription Required

Pregnancy: Consult a doctor before using

May Treat: Hypertension · Anginal pain from vasospastic angina · Anginal pain in coronary artery disease

Brand Names: Procardia · Adalat CC · Procardia XL · Nifediac CC · Nifedical XL and more

Drug Class: Calcium Channel Blockers - Dihydropyridines

Availability: Prescription Required

Pregnancy: Consult a doctor before using

Lactation: Does not adversely affect lactation

Driving: May cause drowsiness or dizziness. Use caution

Precautions

  • Avoid taking grapefruit juice/grapefruit with med
  • May make you dizzy. Use caution when driving.
  • Tell doctor your complete medical history

  • Avoid taking grapefruit juice/grapefruit with med
  • May make you dizzy. Use caution when driving.
  • Tell doctor your complete medical history
  • Review all drugs you are taking with your doctor
  • Be careful not to stand up too quickly
  • For capsule products : Swallow whole. Do not break/chew/crush/dissolve. Important to try not to skip doses. Do not use to stop angina attack. Use regularly. Caution.
  • For tablet, extended release products : Do not chew or crush. OK to split tablet if scored. Take on an empty stomach. Take doses regularly, even when feeling well. It is important to check blood pressure regularly.
  • For tablet, extended release 24 hr products : Empty tablet shell may appear in stool.

Medical uses

Side effects

Overdose

Mechanism of action

Nifedipine (3,5-dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate ), sold under the brand name Adalat and Procardia, among others, is a calcium channel blocker medication used to manage angina, high blood pressure, Raynaud's phenomenon, and premature labor. It is one of the treatments of choice for Prinzmetal angina. It may be used to treat severe high …

History

The approved uses are for the long-term treatment of hypertension and angina pectoris. In hypertension, recent clinical guidelines generally favour diuretics and ACE inhibitors, although calcium channel antagonists, along with thiazide diuretics, are still favoured as primary treatment for patients over 55 and black patients.
Nifedipine given as sublingual administration has previously been used in hypertensive emergenci…

Society and culture

Nifedipine rapidly lowers blood pressure, and patients are commonly warned they may feel dizzy or faint after taking the first few doses. Tachycardia (fast heart rate) may occur as a reaction. These problems are much less frequent in the sustained-release preparations of nifedipine.
Extended release formulations of nifedipine should be taken on an empty stomach, and patients are warned not to consume anything containing grapefruit or grapefruit juice, as they raise blood …

See also

A number of persons have developed toxicity due to acute overdosage with nifedipine, either accidentally or intentionally, and via either oral or parenteral administration. The adverse effects include lethargy, bradycardia, marked hypotension and loss of consciousness. The drug may be quantified in blood or plasma to confirm a diagnosis of poisoning, or to assist in a medicolegal investigation following death. Analytical methods usually involve gas or liquid chromatography a…

1.Nifedipine (Procardia XL): Basics, Side Effects & Reviews

Url:https://www.goodrx.com/nifedipine-er-procardia-xl/what-is

26 hours ago  · Nifedipine (Procardia XL) tablets have extended-release properties, so they absorb in the body slowly over time and can take up to 6 hours to reach its "peak" effect. The immediate …

2.Nifedipine: Side Effects, Dosage, Uses, and More

Url:https://www.healthline.com/health/nifedipine-oral-tablet

28 hours ago The information provided in Name of the medicinal product of Procardia (Nifedipine) is based on data of another medicine with exactly the same composition as the Procardia (Nifedipine). . Be …

3.Nifedipine - Wikipedia

Url:https://en.wikipedia.org/wiki/Nifedipine

11 hours ago  · Nifedipine tablets are an extended-release form of the drug. Nifedipine is also available in immediate-release oral capsules. The capsules are available as the brand-name …

4.Comparison of two formulations of nifedipine during 24 …

Url:https://pubmed.ncbi.nlm.nih.gov/8888089/

10 hours ago Study objective: To determine if one commercial extended-release formulation of nifedipine (Adalat CC) is as effective as another (procardia XL) in controlling blood pressure over 24 …

5.Effects of treatment with nifedipine and metoprolol in …

Url:https://pubmed.ncbi.nlm.nih.gov/7075644/

13 hours ago Both nifedipine and metoprolol used as mono-therapy caused statistically significant reductions of arterial pressure. The addition of metoprolol to nifedipine tended to reduce blood pressure …

6.Nifedipine and Hydrochlorothiazide drug interactions

Url:https://www.ehealthme.com/drug-interaction/nifedipine/hydrochlorothiazide/

11 hours ago The study uses data from the FDA. It is based on nifedipine and hydrochlorothiazide (the active ingredients of Nifedipine and Hydrochlorothiazide, respectively), and Nifedipine and …

7.Compare Diltiazem vs Nifedipine - Iodine.com

Url:https://www.iodine.com/compare/diltiazem-vs-nifedipine

31 hours ago Procardia (Nifedipine) Lowers blood pressure and controls heart rate. Diltiazem works well to lower blood pressure and prevent chest pain, but you have to be okay with avoiding alcohol. …

8.Amlodipine vs Nifedipine Comparison - Drugs.com

Url:https://www.drugs.com/compare/amlodipine-vs-nifedipine

15 hours ago Amlodipine has an average rating of 4.2 out of 10 from a total of 730 ratings on Drugs.com. 26% of reviewers reported a positive effect, while 57% reported a negative effect. Nifedipine has an …

9.nifedipine (Adalat, Procardia) Uses, Side Effects

Url:https://www.medicinenet.com/nifedipine/article.htm

7 hours ago Nifedipine (Adalat, Procardia, Afeditab, Nifediac) is in the drug class of calcium channel blockers ( CCBs ). Nifedipine (Adalat, Procardia, Afeditab, Nifediac) is prescribed for the treatment of …

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