Precautions
Talk with the doctor. The Stadol brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available. It is used to ease pain. This medicine is only for use when other pain drugs do not treat your pain well enough or you cannot take them.
Is there a generic for Stadol?
blurred vision. What is Stadol? Stadol (butorphanol tartrate) is a narcotic pain reliever, similar to morphine used to treat moderate to severe pain. Stadol is also used as part of anesthesia for surgery, or during early labor (if childbirth is expected to be more than 4 hours away).
What is Stadol used to treat?
Talk with your doctor and pharmacist to make sure it is safe to use Stadol (butorphanol injection solution) with all of your drugs. Do not take with alcohol or products that have alcohol. Unsafe and sometimes deadly effects may happen. Get medical help right away if you feel very sleepy, very dizzy, or if you pass out.
Is it safe to take Stadol with other medications?
Migraine headache pain: The analgesic efficacy of two 1-mg doses 1 hour apart of Stadol NS in migraine headache pain was compared with a single dose of 10 mg IM methadone (31 and 32 patients, respectively). Significant onset of analgesia occurred within 15 minutes for both Stadol NS and IM methadone.
How long does it take for Stadol NS to kick in?
Is butorphanol nasal spray still available?
This medicine is available only under a restricted distribution program called the Opioid Analgesic REMS (Risk Evaluation and Mitigation Strategy) program. This product is available in the following dosage forms: Spray.
Is Stadol still used for migraines?
BRAND NAME(S): Stadol NS. USES: This medication is used to treat moderate to severe pain, including pain from surgery, muscle pain, and migraine headaches.
Is butorphanol available?
Butorphanol is an opioid medication reserved for pain that has not responded well to other non-opioid pain medications. It usually comes as a nose spray, but it's also available as an intravenous (IV) injection. It has a lower risk of abuse than other opioids.
Is Stadol and Demerol the same?
Stadol: Stadol has been found to relieve pain when given in the first stage of labor. This narcotic is considered more potent than Demerol. It is usually given intravenously in small doses, usually 1 to 2 mg.
What is the strongest medication for migraines?
Dihydroergotamine (D.H.E. Available as a nasal spray or injection, this drug is most effective when taken shortly after the start of migraine symptoms for migraines that tend to last longer than 24 hours. Side effects can include worsening of migraine-related vomiting and nausea.
How does Stadol make you feel?
The most frequently reported adverse experiences across all clinical trials with butorphanol tartrate injection and butorphanol tartrate nasal spray were somnolence (43%), dizziness (19%), nausea and/or vomiting (13%).
How strong is stadol?
The usual dose of STADOL Injection is 2 mg IV shortly before induction and/or 0.5 to 1.0 mg IV in increments during anesthesia. The increment may be higher, up to 0.06 mg/kg (4 mg/70 kg), depending on previous sedative, analgesic, and hypnotic drugs administered.
Can butorphanol make you high?
Symptoms Of Butorphanol Abuse As with other opioids, butorphanol can cause a euphoric high in patients, which is something people may find desirable with this medication. Physicians are instructed to assess patients for misuse potential before prescribing this medication.
What is the brand name for butorphanol?
Butorphanol (brand names: Stadol®, Torbutrol®, Torbugesic®, Dolorex®) is a systemic partial opiate agonist/antagonist used as an analgesic (pain control medication), pre-anesthetic, antitussive (cough suppressant), or antiemetic (prevents vomiting).
Is Dilaudid stronger than morphine?
Prescribed at Dilaudid®, it is used as a pain reliever. Hydromorphone is 2-8x more potent than morphine but shorter duration and greater sedation.
What does Stadol show up on drug test?
Does Stadol Show Up On a Drug Test? Yes, butorphanol or Stadol can be detected in a drug test. However, the type of test may be a factor in whether or not it will show up. The test that you select must specifically include this drug as part of the panel of drugs being tested.
What do they give you for a migraine at the ER?
If you have an intractable migraine, or status migrainosus: Your ER doctor may give you a drug called dihydroergotamine (DHE-45) as an injection or through an IV, along with metoclopramide. They may also give you valproate in an IV. You may need to check into the hospital for a few days of these treatments.
How strong is stadol?
The usual dose of STADOL Injection is 2 mg IV shortly before induction and/or 0.5 to 1.0 mg IV in increments during anesthesia. The increment may be higher, up to 0.06 mg/kg (4 mg/70 kg), depending on previous sedative, analgesic, and hypnotic drugs administered.
What is a cocktail for migraine?
A migraine cocktail is a combination of medications that's given to treat severe migraine symptoms. The exact medications used in a migraine cocktail can vary, but it typically includes triptans, NSAIDs, and antiemetics. A migraine cocktail is also available in OTC medication.
How often can you have stadol?
If instructed by your doctor, this dose of butorphanol tartrate nasal spray may be repeated every 3 to 4 hours as needed for pain relief.
What is a stadol nasal spray?
Stadol (butorphanol tartrate) Injection and Stadol NS (butorphanol tartrate) Nasal Spray are indicated for the management of pain when the use of an opioid analgesic is appropriate.
Why is butorphanol not recommended for use in patients below 18 years of age?
Butorphanol is not recommended for use in patients below 18 years of age because safety and efficacy have not been established in this population.
How long does it take for butorphanol to work?
Onset of analgesia is within a few minutes for intravenous administration, within 15 minutes for intramuscular injection, and within 15 minutes for the nasal spray doses.
How is butorphanol eliminated?
Elimination occurs by urine and fecal excretion. When 3 H labelled butorphanol is administered to normal subjects, most (70–80%) of the dose is recovered in the urine, while approximately 15% is recovered in the feces. About 5% of the dose is recovered in the urine as butorphanol.
Why is it important to monitor butorphanol?
Proper patient selection, dose and prescribing limitations, appropriate directions for use, and frequent monitoring are important to minimize the risk of abuse and physical dependence with butorphanol tartrate. Special care should be exercised in administering butorphanol to patients with a history of drug abuse or to patients receiving the drug on a continuous basis for an extended period.
How long does butorphanol affect you?
Effects such as drowsiness or dizziness can appear, usually within the first hour after dosing. These effects may persist for varying periods of time after dosing. Patients who have taken butorphanol should not drive or operate dangerous machinery for at least 1 hour and until the effects of the drug are no longer present.
What are the symptoms of butorphanol overdose?
The most serious symptoms are hypoventilation, cardiovascular insufficiency, coma, and death. Butorphanol overdose may be associated with ingestion of multiple drugs (see ADVERSE REACTIONS: Postmarketing Experience ).
How is this medicine (Stadol) best taken?
Use Stadol (butorphanol injection solution) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
What are some other side effects of Stadol?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
What do I need to tell my doctor BEFORE I take Stadol?
Tell your doctor about the allergy and what signs you had.
How do I store and/or throw out Stadol?
If you need to store Stadol (butorphanol injection solution) at home, talk with your doctor, nurse, or pharmacist about how to store it.
How to avoid passing out from stadol?
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Be careful going up and down stairs.
Can you overdose on stadol?
This medicine is a strong pain drug that can put you at risk for addiction, abuse, and misuse. Misuse or abuse of Stadol ( butorphanol injection solution) can lead to overdose and death. Talk with your doctor.
Can you take stadol if you are 65?
If you are 65 or older, use Stadol (butorphanol injection solution) with care. You could have more side effects.
What medications can affect butorphanol?
Examples include azole antifungals (such as ketoconazole), macrolide antibiotics (such as erythromycin), HIV medications (such as ritonavir), rifamycins (such as rifabutin, rifampin), certain drugs used to treat seizures (such as carbamazepine, phenytoin), among others.
What is butorphanol used for?
This medication is used to treat moderate to severe pain, including pain from surgery, muscle pain, and migraine headaches. Butorphanol is an opioid pain reliever similar to morphine. It acts on certain centers in the brain to give you pain relief.
Can butorphanol cause withdrawal?
Butorphanol can cause withdrawal reactions in people who are physically dependent on opioids. The seriousness of the withdrawal symptoms depends on the level of dependence and the dose of butorphanol. Tell your doctor right away if you develop symptoms such as anxiety, agitation, trouble sleeping, sweating, stomach cramps, and diarrhea.
Can butorphanol block opioids?
Butorphanol can also block the effects of opioids and can cause withdrawal symptoms in people dependent on opioids. If possible, people who have recently used opioids in high doses or for a long time should not use butorphanol. (See also Side Effects section.)
How Should Stadol Be Taken?
Butorphanol is given as an injection into a muscle or a vein. It is also available as a nasal spray.
What is Stadol?
Stadol (butorphanol tartrate) is a narcotic pain reliever, similar to morphine used to treat moderate to severe pain. Stadol is also used as part of anesthesia for surgery, or during early labor (if childbirth is expected to be more than 4 hours away). The brand name Stadol is no longer manufactured and can only be found in generic form.
How to report a drug side effect?
You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.
Where does RXList come from?
All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA). Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug ...
Can you take stadol with other narcotics?
Dangerous side effects or death can occur when alcohol is combined with Stadol. Do not use Stadol with other narcotic pain medications, sedatives, tranquilizers, muscle relaxers, or other medicines that can cause sleepiness or slow your breathing.
Does RXList cover drug interactions?
The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.
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As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.
What It Is
This medication is used to treat moderate to severe pain, including pain from surgery, muscle pain, and migraine headaches.
Status: Discontinued
May Treat: General anesthesia adjunct · Labor pain · Pain · Sedation as adjunct to anesthesia
Alternate Brand Names: Stadol NS
Drug Class: Analgesic Opioid Partial-Mixed Agonists
Availability: Prescription Required
Status: Discontinued
May Treat: General anesthesia adjunct · Labor pain · Pain · Sedation as adjunct to anesthesia
Alternate Brand Names: Stadol NS
Drug Class: Analgesic Opioid Partial-Mixed Agonists
Availability: Prescription Required
Pregnancy: Consult a doctor before using
Lactation: Consult a doctor before using
Alcohol: Avoid intake while taking this medication
Driving: May cause drowsiness or dizziness. Use caution
Addiction: Risk of abuse and addiction. Use only as directed
- Important to read patient package insert& med guide
- Discuss risks/benefits if woman of childbearing age
- Know how to use before taking.
- Important to read patient package insert& med guide
- Discuss risks/benefits if woman of childbearing age
- Know how to use before taking.
- May make you drowsy or dizzy. Drive with caution
- Avoid alcohol/other drugs that make you sleepy
- Call Dr before increasing dose or frequency.
- Taking a larger dose may cause breathing problems.
- May be habit forming
How It Works
Side Effects
Safety
Complications
- Stadol is the brand name of a pain reliever developed and sold by the Bristol Myers Squibb pharmaceutical company. It is now discontinued. However, the drug is still available in the US under the generic name of butorphanol as well as in other countries under different brand names. Butorphanol is a narcotic analgesic medication and an opioid agonis...
Choosing to Use Pain Medication
- A narcotic analgesic can relieve moderate to severe pain during labor. It can make you feel more comfortable by: 1. Calming anxiety. 2. Helping the body relax. 3. Relieving the intense pain of contractions. 4. Making you sleepy so you can rest between contractions. This type of pain reliever can help to lessen the pain, but it does not block it completely. So, it allows you to feel e…
Breastfeeding
- During labor, the goal is to relieve the pain without putting you at risk for harm or severe side effects. Studies show that butorphanol is a safe, low cost, and effective medication for pain relief during labor.3 However, like all medications, side effects are possible. They can affect both you and your baby.
Stadol Description
- While you are taking this medication, you may have to follow some safety precautions. 1. You may not be allowed to walk around if you are drowsy or dizzy. 2. You may not be allowed to eat or drink. 3. You may need IV fluids. 4. You may need oxygen. 5. You and your baby may need more monitoring.
Stadol - Clinical Pharmacology
- There are benefits to taking medication during labor, but there are also risks. Complications can develop from the use of an opioid pain reliever during labor.8 Butorphanol can cause: Allergy.An allergic reaction such as hives, itching, difficulty breathing, or swelling in the face, neck, tongue, or throat. Respiratory depression.Too much of this medicine can lead to an overdose wit…
Indications and Usage For Stadol
- At some point, most expecting mothers give at least a little thought to how they want to get through labor. Some moms wish to as natural a birth as possible without any medications, and others know they want medicine at the first sign of labor. Many things can influence your choice.10 These include: 1. Concern about the dangers of pain medicine 2. Fear of pain 3. Ho…
Contraindications
- When butorphanol is given at least four hours before delivery, the chances of it interfering with breastfeeding are low. But, when used close to birth, narcotic medication can cause drowsiness in both the mom and baby. The effects could lead to difficulty with feeding and breastfeedingafter the baby is born. If a mom is using butorphanol after birth, it can pass in the breast milk and cause d…
Warnings
Precautions
- General Pharmacology and Mechanism of Action
Butorphanol is a mixed agonist-antagonist with low intrinsic activity at receptors of the µ-opioid type (morphine-like). It is also an agonist at κ-opioid receptors. Its interactions with these receptors in the central nervous system apparently mediate most of its pharmacologic effects, in… - Pharmacodynamics
The analgesic effect of butorphanol is influenced by the route of administration. Onset of analgesia is within a few minutes for intravenous administration, within 15 minutes for intramuscular injection, and within 15 minutes for the nasal spray doses. Peak analgesic activity …
Adverse Reactions
- Stadol (butorphanol tartrate) Injection and Stadol NS (butorphanol tartrate) Nasal Spray are indicated for the management of pain when the use of an opioid analgesic is appropriate. Stadol Injection is also indicated as a preoperative or preanesthetic medication, as a supplement to balanced anesthesia, and for the relief of pain during labor.
Drug Abuse and Dependence
- Stadol Injection and Stadol NS are contraindicated in patients hypersensitive to butorphanol tartrate or the preservative benzethonium chloride in Stadol NS or Stadol Injection in the multi-dose vial.
Overdosage
- Patients Dependent on Narcotics
Because of its opioid antagonist properties, butorphanol is not recommended for use in patients dependent on narcotics. Such patients should have an adequate period of withdrawal from opioid drugs prior to beginning butorphanol therapy. In patients taking opioid analgesics chronically, bu… - Drug Abuse and Dependence
Drug Abuse—Butorphanol tartrate, by all routes of administration, has been associated with episodes of abuse. Of the cases received, there were more reports of abuse with the nasal spray formulation than with the injectable formulation. Physical Dependence, Tolerance, and Withdraw…
Stadol Dosage and Administration
- General
Hypotension associated with syncope during the first hour of dosing with Stadol NS has been reported rarely, particularly in patients with past history of similar reactions to opioid analgesics. Therefore, patients should be advised to avoid activities with potential risks. - Head Injury and Increased Intracranial Pressure
As with other opioids, the use of butorphanol in patients with head injury may be associated with carbon dioxide retention and secondary elevation of cerebrospinal fluid pressure, drug-induced miosis, and alterations in mental state that would obscure the interpretation of the clinical cours…