is topiramate a benzo

Precautions

Topiramate, sold under the brand name Topamax among others, is a medication used to treat epilepsy and prevent migraines. It has also been used in alcohol dependence.

What is topiramate (Topamax)?

Topiramate in benzodiazepine withdrawal There is an increasing interest in anticonvulsants for the treatment of benzodiazepine withdrawal symptoms. The new anticonvulsant compound topiramate seems to be an especially promising drug for this indication. It acts, among others, as an AMPA antagonist, which may be responsible in part for its …

Can topiramate be used to treat benzodiazepine withdrawal?

Alprazolam is successful in reducing anxiety but has a high addictive/misuse potential. Topiramate is a novel anticonvulsant which has been used as a mood stabilizer. Other anticonvulsants, such as carbamazepine and valproate, have been used in alcohol and benzodiazepine withdrawal.

What is the difference between alprazolam and topiramate?

Topiramate can increase body temperature and decrease sweating, leading to life-threatening dehydration (especially in children). Avoid the use of a ketogenic or "ketosis" diet (high in fat, low in carbohydrates) while you are taking topiramate. Topiramate may cause blurred vision or impair your thinking or reactions.

What are the side effects of topiramate?

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What are benzodiazepines?

Benzodiazepines are a type of sedative medication. This means they slow down the body and brain's functions. They can be used to help with anxiety and insomnia (difficult getting to sleep or staying asleep)....This means these drugs can:make you feel relaxed and sleepy (sedation)reduce your anxiety.relax your muscles.

Does Topamax help anxiety?

Topamax for anxiety Topamax isn't approved to treat anxiety. However, the drug may sometimes be used off-label to treat people with certain anxiety disorders, such as obsessive-compulsive disorder (OCD).

Can I take topiramate with Xanax?

ALPRAZolam topiramate Using ALPRAZolam together with topiramate may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination.

Is Gabapentin a benzodiazepine?

Gabapentin is used off-label to treat anxiety. Xanax belongs to a different drug class called benzodiazepines, and is used primarily to treat anxiety disorders and panic attacks. Brand names for gabapentin include Neurontin, Horizant, and Gralise.

What is Topamax used for in mental health?

Topiramate is a medication that works in the brain and is sometimes used in patients with bipolar disorder (also known as manic depression). It is approved for the treatment of seizures (epilepsy) in adults and children in combination with other anticonvulsants and for preventing migraine headaches in adults.

Is Topamax a sedating?

Topamax has a number of common side effects, which its manufacturer states are “mild to moderate.” One common side effect of the drug is somnolence, or sleepiness. Some doctors and patients have dubbed the drug “Sleepomax” because of its heavy sedative effects.

What can you not mix with topiramate?

What not to take with topiramate?Valproic acid (brand name examples: Depakote). ... Zonisamide (brand name example: Zonegran). ... Glaucoma medications, including eye drops.Birth control pills. ... Any medicines that impair or decrease your thinking, concentration, or muscle coordination.

What does Topamax do to the brain?

Topiramate is in a class of medications called anticonvulsants. It works by decreasing abnormal excitement in the brain.

What is the most common side effect of topiramate?

Tiredness, drowsiness, dizziness, loss of coordination, tingling of the hands/feet, loss of appetite, bad taste in your mouth, diarrhea, and weight loss may occur.

Is Wellbutrin a benzodiazepine?

Wellbutrin is not a benzodiazepine. Benzodiazepines work by stimulating receptors in the brain called GABA receptors, causing an effect that depresses normal activity and brain function. Wellbutrin does not act on these receptors and is therefore not considered a benzodiazepine.

What is less addictive than Xanax?

In general, Ativan causes fewer withdrawal symptoms and has less potential for misuse than Xanax.

What will gabapentin test positive for?

Nearly all gabapentin positive postmortem cases were also positive for an opioid, the most significant being fentanyl, suggesting that gabapentin misuse may be due to its potentiating effect of opioid drug action. This study also highlights the limited utility of immunoassay-based urine drug screens.

Does Topamax increase anxiety?

Anticonvulsants like Topamax, can also profoundly affect mood, contributing to mental illnesses like anxiety, depression, or mania. Topamax can have several neurocognitive and neuropsychiatric side effects, including this case of Topamax-induced dissociative disorder.

Is Topamax a mood stabilizer?

Topiramate is a novel anticonvulsant agent with a broad spectrum mechanism of action, and recent clinical reports indicate that it may have mood stabilizing properties in bipolar disorder.

Can Topamax cause panic attacks?

However, it has been hypothesized that topiramate's carbonic anhydrase properties may elevate central CO2 levels, which create a panicogenic effect. Hence, in vulnerable persons this pharmacologic action could trigger panic attacks or worsen a pre-existing disorder.

Is topiramate an antidepressant?

The bottom line. Topamax isn't approved to treat depression or bipolar disorder with depression, but it may be helpful for people who have not found relief with other mood-stabilizing drugs. For this reason, a doctor may decide, after careful evaluation, to prescribe Topamax off label for treating depression.

Does topiramate cause weight loss?

Yes, topiramate (Topamax) has been shown to cause weight loss when used for both seizure control and migraine prevention. Topiramate by itself is n...

Does topiramate cause hair loss?

Yes, topiramate has been shown to cause hair loss in studies, but it is not a common side effect. Hair loss (also called alopecia) has been reporte...

How long do you stay on Topamax for migraines?

You can usually stay on Topamax (topiramate) to help prevent your migraine headaches as long as the treatment is needed and remains safe for you. Y...

How long does it take for Topamax to start working?

It may take 8 to 12 weeks for you to see the full effect of Topamax on your migraine headaches. In clinical studies, some people had fewer headache...

How long does Topamax stay in your system?

Topamax stays in your system for approximately 4 to 5 days after the last dose, but this may vary depending on personal factors, such as your age,...

How does Trokendi XR help with weight loss?

Trokendi (topiramate) XR can lead to weight loss when used for prevention of migraine headaches or seizures, but it is not approved as a weight los...

What is topiramate used for?

Topiramate is a seizure medicine, also called an anticonvulsant. Topiramate is used to treat certain types of seizures in adults and children who are at least 2 years old. Trokendi XR is for use in adults and children who are at least 6 years old. Some brands of topiramate are also used to prevent migraine headaches in adults ...

What other drugs will affect topiramate?

Using topiramate with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or depression.

How should I take topiramate?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

What is the difference between Trokendi XR and Topiramate?

Topiramate is a seizure medicine, also called an anticonvulsant. Topiramate is used to treat certain types of seizures in adults and children who are at least 2 years old. Trokendi XR is for use in adults and children who are at least 6 years old.

What to do if you have seizures while taking topiramate?

Call your doctor if your seizures get worse or you have them more often while taking topiramate.

Can topiramate be changed?

Topiramate doses are sometimes based on weight in children. Your child's dose needs may change if the child gains or loses weight.

Can topiramate be taken with food?

Topiramate can be taken with or without food.

What does Topamax do?

This prevents excessive electrical signals from building up in the nerve cells. As a result, the nerve cells stop firing inappropriate or excessive signals.

What is the active ingredient in Topamax?

Topamax contains the active drug topiramate. Topamax belongs to a class of drugs called anticonvulsants. (A class of drugs is a group of medications that work in a similar way.) Anticonvulsant drugs work in your brain to help prevent seizures. Some of these drugs, including Topamax, can also prevent migraine headaches. Topamax is typically taken every day.

How long does it take to flush Topamax out of your system?

It takes about five half-lives for a drug to be almost completely removed from your body. So for Topamax, most of the drug will be flushed out of your system within about 5 days after you stop taking it.

Is Topamax a controlled substance?

No, it’s not. Topamax is available only by prescription from your doctor, but it’s not a controlled substance.

Is Topamax a mood stabilizer?

Topamax is sometimes used off-label * as a mood stabilizer in people with bipolar disorder. Mood stabilizers are drugs that help prevent extreme changes in mood, such as those that occur with bipolar disorder. People with bipolar disorder typically have episodes of depression and episodes of mania. Mania is a mood disorder that gives you an unnatural feeling of physical and mental energy.

How old do you have to be to take Topamax?

The usual recommended dosage of Topamax in children ages 12 years and older is the same as it is for adults. For details, see the “Dosage for preventing migraine headaches” section above.

How many mg is Topamax?

Topamax comes in two different forms: A tablet that you swallow. It’s available in strengths of 25 milligrams (mg), 50 mg, 100 mg, and 200 mg. A sprinkle capsule. The capsule can be swallowed whole or opened to sprinkle on a spoonful of soft food and swallowed. The capsule is available in strengths of 15 mg and 25 mg.

What is the drug topiramate used for?

Topiramate, sold under the brand name Topamax among others, is a carbonic anhydrase inhibitor medication used to treat epilepsy and prevent migraines. It has also been used in alcohol dependence. For epilepsy this includes treatment for generalized or focal seizures. It is taken by mouth.

How is topiramate metabolized?

Topiramate is quickly absorbed after oral use. Most of the drug (70%) is excreted in the urine unchanged. The remainder is extensively metabolized by hydroxylation, hydrolysis, and glucuronidation. Six metabolites have been identified in humans, none of which constitutes more than 5% of an administered dose.

What are the targets of topiramate?

These include (1) voltage-gated sodium channels; (2) high-voltage-activated calcium channels; (3) GABA-A receptors; (4) AMPA/kainate receptors; and (5) carbonic anhydrase isoenzymes. There is evidence that topiramate may alter the activity of its targets by modifying their phosphorylation state instead of by a direct action. The effect on sodium channels could be of particular relevance for seizure protection. Although topiramate does inhibit high-voltage-activated calcium channels, the relevance to clinical activity is uncertain. Effects on specific GABA-A receptor isoforms could also contribute to the antiseizure activity of the drug. Topiramate selectively inhibits cytosolic (type II) and membrane associated (type IV) forms of carbonic anhydrase. The action on carbonic anhydrase isoenzymes may contribute to the drug's side-effects, including its propensity to cause metabolic acidosis and calcium phosphate kidney stones.

What is the drug used for epilepsy?

Topiramate. Topiramate, sold under the brand name Topamax among others, is a carbonic anhydrase inhibitor medication used to treat epilepsy and prevent migraines. It has also been used in alcohol dependence. For epilepsy this includes treatment for generalized or focal seizures.

When was topiramate approved?

Topiramate was approved for medical use in the United States in 1996. It is available as a generic medication. In 2018, it was the 89th most commonly prescribed medication in the United States, with more than 8 million prescriptions.

What is the use of Phentermine?

Other uses include treatment of obesity and antipsychotic - induced weight gain. It is being studied to treat post traumatic stress disorder. In 2012, the combination phentermine/topiramate was approved in the United States for weight loss.

Can topiramate cause dehydration?

Use caution with activities leading to an increased core temperature, such as strenuous exercise, exposure to extreme heat, or dehydration. Topiramate may cause visual field defects. Topiramate may decrease effectiveness of oestrogen-containing oral contraceptives.

What is Topamax?

Topamax has active ingredients of topiramate. It is often used in migraine. eHealthMe is studying from 52,458 Topamax users for its effectiveness, alternative drugs and more.

What is phase IV of Topamax?

The phase IV clinical study analyzes which people take Topamax and have Drug screen false positive. It is created by eHealthMe based on reports of 46,725 people who have side effects when taking Topamax from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

How many drugs are false positives?

Drug screen false positive is found to be associated with 670 drugs and 365 conditions by eHealthMe.

Is Topamax based on generic drugs?

It is based on topiramate (the active ingredients of Topamax) and Topamax (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

3-Me-PCPy arrived and I immediately tried it because I'm stupid

Received tiny white crystals with light plastic/glue smell or what I would describe 'new laptop' smell. Smell after insufflation is somewhat fruity. Weighted out 5mg (+/-5mg with my scale I'd think).

Fuck Please Pay ATTENTION To Scales

i just weighed up 30mg of a-pihp and was like wtf why does it look like 100mg+ plus turns out I was in OZ!!!!

PSA: Hamilton Morris posted an interview with Dr. Carl Hart on his Patreon this morning

I’m halfway through it right now. I haven’t heard any mentions of any RCs yet, but I still figured this sub would be interested in a serious conversation about drug policy and pharmacology.

My cocaine and pyro fueled psychosis (long post)

All of this is true and im still dealing w the consequences of my actions a month later. Im abstaining from all substances now because of my habit and im seeking treatment. These drugs can definitely be used responsibly, this is just an actual example of the consequences of not using them responsibly.

Have research chemicals PERMANENTLY and negativity impacted your life?

One of the biggest problems with 90% of trip reports on this sub is that they are written within a few days of the trip ending.

Has anyone tried TBG (tabernanthalog), a non-hallucinogenic psychedelic ?

So TBG is a newly synthesized ibogaine analog, so I'm not sure its even available anywhere, but I'm really curious to hear about how a supposedly non-hallucinogenic psychedelic could be like.

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