Versed. This prescription medication works to reduce anxiety, cause sleepiness, relax the muscles, and impair short-term memory by enhancing the effects of a certain brain chemical. Versed comes in the form of an injection or a syrup and is very fast acting. Side effects can include breathing problems, tenderness at the injection site, and nausea.
What is versed used to treat?
For the book of poetry, see Versed. Midazolam, sold under the brand name Versed, among others, is a benzodiazepine medication used for anesthesia, procedural sedation, trouble sleeping, and severe agitation. It works by inducing sleepiness, decreasing anxiety, and causing a loss of ability to create new memories.
What is midazolam (Versed)?
What is Midazolam? What is Midazolam? Midazolam (the brand name for the drug "versed") is an FDA approved benzodiazepine, which is a class of drugs that produce sedative effects on the body and central nervous system (CNS). It works by increasing the effect of GABA (a natural chemical) in the brain.
Does versed affect the autonomic nervous system?
However, the effects of Versed on the cardiac autonomic nervous system, which has a vital role in neural control for maintaining cardio- vascular stability, have not been well studied. Is Versed bad for kidneys? Versed has delayed metabolism and elimination in renal impairment and should be avoided.
Is it possible to miss a dose of versed?
In a medical setting you are not likely to miss a dose. What happens if I overdose? In a medical setting an overdose would be treated quickly. What happen If I stop taking Versed?
How long does it take for Versed to wear off?
Effects last from one to six hours. Midazolam has an amnesia effect, which lasts anywhere from 20 minutes to an hour. Most of a dose of midazolam is eliminated via urine, although some are eliminated via feces as well. For most adults, an entire dose of midazolam is eliminated within a day.
What type of drug is Versed?
It belongs to a class of drugs known as benzodiazepines.
What is Versed mechanism of action?
The mechanism of action of midazolam indirect and is related to GABA accumulation and its affinity to the benzodiazepine receptors. Two separate receptors for GABA and benzodiazepine couple to a common chloride channel. It increases the frequency of chloride channel opening.
Does Versed knock you out?
Versed may be a wonderful sedative (a drug that treats anxiety) and hypnotic (a drug that induces sleep), but it is NOT a general anesthetic (induces unconsciousness)—something that the idiots in an Oklahoma prison learned at the expense of a convicted murderer, who they were trying to execute with the wrong drugs.
Is midazolam short or long acting?
Midazolam is a new ultra short-acting benzodiazepine whose physical dependence properties have not been well characterized.
What is the difference between Ativan and Versed?
Ativan and other benzodiazepines may act by enhancing the effects of gamma-aminobutyric acid (GABA), a neurotransmitter, in the brain to reduce activity. Versed (midazolam) belongs to a class of medications called benzodiazepines, which produce a calming effect on the central nervous system.
Which is the longest acting benzodiazepine?
Comparing benzodiazepines mainly used for anxietyLong-acting drugsGeneric nameTrade namesHalf-lifealprazolamXanax12 to 15 hourslorazepamAtivan10 to 20 hoursoxazepamnone6 to 20 hours3 more rows
Is midazolam stronger than diazepam?
Abstract. Midazolam is a new imidazobenzodiazepine. It is more potent and has a shorter duration of action than diazepam. Forty patients undergoing upper gastrointestinal endoscopy for the first time were randomized to receive either diazepam or midazolam as the preendoscopic sedative agent.
What is the half-life of midazolam?
Distribution half-life was 18.7 minutes (13 to 47 minutes) after IV administration and 41 minutes (30 to 80 minutes) after IM administration. Elimination half-life was 98 minutes (67 to 373 minutes) and 234 minutes (103 to 320 minutes) after IV and IM administration, respectively.
What drug puts you to sleep instantly?
About zolpidem Zolpidem is a sleeping pill. It's used to treat insomnia (when you might have trouble getting to sleep and staying asleep). It helps you fall asleep more quickly and makes you less likely to wake up during the night. Zolpidem comes as tablets.
What medication reverses Versed?
Romazicon (Flumazenil) is a benzodiazepine antogonist used to reverse Versed (Midazolam) and Valium (Diazepam). It also has a rapid onset of action, producing a reversal in less than one minute.
What are side effects of Versed?
Common side effects may include:amnesia;headache, drowsiness;hiccups;nausea, vomiting; or.pain, redness, or a hard lump where the medicine was injected.
Is Versed considered a narcotic?
In the United States, midazolam (DEA number 2884) is on the Schedule IV list of the Controlled Substances Act as a non-narcotic agent with low potential for abuse.
What type of anesthesia is Versed?
Since Versed is a surgical anesthetic, it is not a drug that is continuously used and risks building up in your system.
Is Versed A benzodiazepines?
Versed is a benzodiazepine (ben-zoe-dye-AZE-eh-peen) that is used to help you relax before having a minor surgery, dental work, or other medical procedure. Versed may also be used for purposes not listed in this medication guide.
Is Versed like Xanax?
Midazolam Injection is used as a sedative before surgery or other medical procedures. Midazolam hydrochloride syrup is used in pediatric patients. Brand names for midazolam include Versed. Xanax is used as an anti-anxiety medication prescribed to treat panic attacks and anxiety disorders.
What is Versed used for?
Versed is a benzodiazepine medication used for anesthesia, procedural sedation, trouble sleeping, and severe agitation. Versed injection is used to...
How safe is Versed?
Versed is an extremely useful and safe medication for both inpatients and outpatients.
How does Versed work?
Versed work by increasing the effect of a certain natural chemical (GABA) in the brain.
What are the common side effects of Versed?
Common side effects of Versed are Nausea, vomiting, dizziness, or drowsiness may occur. If any of these effects persist or worsen, notify the docto...
Is Versed safe during pregnancy?
Versed be avoided for use as general anesthesia and sedation during the third trimester of pregnancy for surgeries not related to delivery of the b...
Is Versed safe during breastfeeding?
The small amounts of Versed excreted into breastmilk would not be expected to cause adverse effects in most breastfed infants. A safety scoring sys...
Can I drink alcohol with Versed?
Do not drink alcohol while taking Versed. This medication can increase the effects of alcohol. You may feel more drowsy, dizzy, or tired if you tak...
Can I drive after taking Versed?
Avoid driving or hazardous activity until the effects of Versed have worn off completely. Dizziness or drowsiness can cause falls, accidents, or se...
How do I take Versed?
Take this medication by mouth as directed by your doctor. It is usually given as a single dose before a procedure or anesthesia.
Adverse Reactions
Cardiovascular effects – Cardiac arrest, hypotension, bradycardia, PVC's, Tachycardia
Reversal
Flumazenil (Romazicon) will reverse the respiratory effects of midazolam overdose.
What is Midazolam?
Midazolam (the brand name for the drug "versed") is an FDA approved benzodiazepine, which is a class of drugs that produce sedative effects on the body and central nervous system (CNS). It works by increasing the effect of GABA (a natural chemical) in the brain.
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Medical uses
Midazolam is sometimes used for the acute management of seizures. Long-term use for the management of epilepsy is not recommended due to the significant risk of tolerance (which renders midazolam and other benzodiazepines ineffective) and the significant side effect of sedation.
Contraindications
Benzodiazepines require special precaution if used in the elderly, during pregnancy, in children, in alcohol- or other drug-dependent individuals or those with comorbid psychiatric disorders. Additional caution is required in critically ill patients, as accumulation of midazolam and its active metabolites may occur.
Side effects
Side effects of midazolam in the elderly are listed above. People experiencing amnesia as a side effect of midazolam are generally unaware their memory is impaired, unless they had previously known it as a side effect.
Pharmacology
Midazolam is a short-acting benzodiazepine in adults with an elimination half-life of 1.5–2.5 hours. In the elderly, as well as young children and adolescents, the elimination half-life is longer. Midazolam is metabolised into an active metabolite alpha1-hydroxymidazolam.
History
Midazolam is among about 35 benzodiazepines currently used medically, and was synthesized in 1975 by Walser and Fryer at Hoffmann-LaRoche, Inc in the United States. Owing to its water solubility, it was found to be less likely to cause thrombophlebitis than similar drugs.
External links
"Midazolam". Drug Information Portal. U.S. National Library of Medicine.
Short-Acting Stimulants vs. Long-Acting Stimulants
The effects of stimulant medications last for different lengths of time, though they are typically classified as one of the following:
How Long Does ADHD Medication Last?
The exact length of time a stimulant lasts depends on the patient’s metabolism. For example, a long-acting stimulant medication may say it lasts for 8 to 12 hours. Some patients may feel its effects for 10 hours. Others may experience just 6 hours of symptom control.
When do long acting meds release into the bloodstream?
Part of them release into your bloodstream shortly after you take them (typically in the morning) and the rest throughout the day. These meds are a good choice if you need symptom relief all day but want to take just one pill.
What is it called when a med peaks and falls in your bloodstream?
A short-acting med peaks and falls in your bloodstream quickly. You might feel irritable when it wears off. That’s called a rebound effect .
How long do stimulants work?
They work as long as they’re active in the body. Some are good for a few hours, while others can last most of the day. Stimulants are the medications that most people use for ADHD symptoms. They don’t cure it, but they boost levels of chemicals in your brain that help you focus and pay attention.
Dangerous Versions
One of the most dangerous benzodiazepines is flunitrazepam, known by the brand name Rohypnol. This benzodiazepine is still prescribed for limited uses, such as part of a larger narcolepsy treatment plan. However, it is more notorious as a date rape drug.
What Are Benzodiazepines?
Benzodiazepines are some of the most widely prescribed sedative drugs in the United States. Thislass of drugs works on the gamma-aminobutyric acid (GABA) receptors in the brain to slow down how fast neurons fire.
How Benzodiazepines Work in the Brain
GABA is an important neurotransmitter that regulates communication between brain cells. Without enough GABA in the brain, you may feel anxious, experience a panic attack, or have a seizure in the most extreme cases.
Intended for Short-Term Use
No benzodiazepines are intended to be taken for more than two weeks except in some instances of seizure disorders. Many chronic seizure conditions like epilepsy have more targeted medications for treatment, and benzodiazepines are still intended for short-term use for these conditions.
Benzodiazepine Abuse
Unfortunately, because benzodiazepines are widely prescribed, they are also widely abused. This has led to an epidemic alongside opioid abuse in the U.S.
Overcoming Abuse and Addiction
If you take benzodiazepines as prescribed by your doctor and want to stop, you should work with them to safely taper your prescription down until your body is no longer dependent on the drug. Benzodiazepines quickly lead to physical dependence if you take them consistently, even if you do so as prescribed.
Short- vs. Long-Acting: What’s The difference?
- While there are a number of differences between different benzodiazepine drugs, the key difference has to do with their half-life, or the time it takes for the body to process and remove one half of a new dose. If a benzodiazepine has a longer half-life, it will remain active in the body for …
List of Short-Acting Benzodiazepines
- Currently, there are only two short-acting benzodiazepine drugs approved for use in the United States.
Other Risks Associated with Short-Acting Benzodiazepines
- Use of benzodiazepines is associated with a variety of potential adverse effects and side-effectswhether they are used long-term, short-term, or as needed. These effects include: 1. birth defects if taken during the first three months of pregnancy 2. other pregnancy and breastfeeding complications 3. dizziness 4. fatigue 5. poor coordination 6. headache 7. depression 8. memory …
Treating Benzodiazepine Use Disorder
- Benzodiazepine drugs can be severely habit-forming and harmful with long term use. If you or a loved one has developed any level of dependence on a benzodiazepine drug, please contact Ark Behavioral Healthtoday to learn more about our qualified and compassionate detox and rehabilitation services.