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is vitamin d good for diabetes

by Jeanie Pfeffer Published 3 years ago Updated 2 years ago
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Vitamin D supplementation may help lower average blood sugar levels in people with type 2 diabetes; and is especially effective in people who also have a vitamin D deficiency
vitamin D deficiency
Vitamin D deficiency or hypovitaminosis D is a vitamin D level that is below normal. It most commonly occurs in people when they have inadequate exposure to sunlight, particularly sunlight with adequate ultraviolet B rays (UVB).
https://en.wikipedia.org › wiki › Vitamin_D_deficiency
, and are non-obese and deficient. Supplementation for more than 12 weeks at ≥ 1000 IU/day may be most beneficial.
Oct 2, 2018

Full Answer

Can vitamin D reverse diabetes?

Vitamin D cannot reverse diabetes. Type I diabetes mellitus is due to the loss of the ability to make insulin, and this is not currently reversible. Treatment requires insulin.

Are there vitamins that are bad for diabetics?

Vitamin C: People with type 2 diabetes have high levels of oxidative stress due to high blood sugar levels and therefore require more vitamin C which is a potent antioxidant. Vitamin C concentrations have been found to be low in diabetics. Higher vitamin C concentrations are linked to reduced levels of HbA1C and blood glucose.

What are the best vitamins for a diabetic?

What are the best vitamins and supplements for diabetics?

  1. NOW Supplements, Acetyl-L Carnitine 500 mg. Acetyl-L Carnitine could be a non-essential amino acid, which implies that it's created naturally within the body.
  2. Biotin supplement with Organic Coconut Oil. You need biotin (vitamin B8) to release energy from food. ...
  3. Nutricost Alpha Lipoic Acid. ...
  4. Nature's Bounty Chromium Picolinate. ...

More items...

How does a vitamin D deficiency affect diabetes?

  • Observational studies suggest a link between vitamin D and diabetes
  • The potential effect of vitamin D appears to be more prominent among persons at risk for diabetes.
  • The optimal blood 25-hydroxyvitamin D concentration associated with reduced risk of type 2 diabetes is not clear.

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How much vitamin D should a diabetic take?

“Caution should be taken with vitamin D dosages, for people with or without diabetes,” said Smith. “The standard dosage is 400 IUs per day, but for those with diabetes, the current recommended safe daily dose to maintain optimal vitamin D levels is 1,000 to 2,000 IUs per day.”

Does vitamin D reduce blood sugar?

Intake of vitamin D supplements led to a marginally significant decrease in fasting blood glucose [FBS: −12 (4) in the intervention group compared to − 3 (2) in the control group; P = 0.055].

What is the best vitamin for diabetics?

A B12 supplement can be helpful if you have type 2 diabetes and are deficient in the vitamin. People who take metformin for type 2 diabetes have lower levels of vitamin B12. If you're on metformin, talk to your health care provider about periodically being tested for a B12 deficiency.

Can vitamin D raise blood sugar levels?

Recent studies have concluded that people with healthy vitamin D levels may be less likely to develop type-2 diabetes, and vitamin D may help keep blood glucose levels low.

Can vitamin D lower your A1C?

People with type 2 diabetes who took a vitamin D supplement tended to have lower A1C levels (a measure of long-term blood glucose control) than those who didn't take vitamin D, according to a recent study published in the journal Frontiers in Endocrinology.

What's difference between vitamin D and vitamin D3?

There are quite a few differences between vitamin D and vitamin D3 but the main difference between them is that vitamin D is a fat-soluble vitamin that regulates calcium and phosphorous levels of the body whereas the vitamin D3 is the natural form of vitamin D produced by the body from sunlight.

What vitamin lowers blood sugar fast?

Magnesium supplements have shown to reduce fasting blood sugar levels. Every 50mg increase of magnesium dose produced an increasingly better result on blood sugar. Magnesium is responsible for insulin secretion and activity on body tissues.

What is the miracle food for diabetes?

Jamun is a tried and tested fruit for people with type-2 diabetes. According to a study published in the Journal of Food Science and Technology, jamun has antidiabetic and antioxidant functionality.

How can I lower my A1C quickly?

7 Ways to Improve Your A1CExercise. Physical activity helps your body use insulin more efficiently, so it can better process the glucose in your blood. ... Eat Right. ... Take Medications as Prescribed. ... Manage Your Stress. ... Stick to a Schedule. ... Drink in Moderation. ... Monitor Your Numbers.

Can I take metformin and vitamin D at the same time?

No interactions were found between metformin and Vitamin D3.

What are the signs you need vitamin D?

Symptoms of vitamin D deficiency may include:Fatigue.Not sleeping well.Bone pain or achiness.Depression or feelings of sadness.Hair loss.Muscle weakness.Loss of appetite.Getting sick more easily.More items...•

What supplements can I take to lower my A1C level?

10 Supplements to Help Lower Blood SugarCinnamon. Cinnamon supplements are either made from whole cinnamon powder or an extract. ... American Ginseng. ... Probiotics. ... Aloe Vera. ... Berberine. ... Vitamin D. ... Gymnema. ... Magnesium.More items...•

Does vitamin D Help insulin resistance?

[1,2] Vitamin D increases insulin sensitivity through the effect on its muscle cell receptors by increasing insulin receptor or increasing the sensitivity of insulin receptor to insulin and the effect on peroxisome proliferator-activated receptor (PPAR) δ and the influence on regulation of extracellular calcium.

Why do diabetics have low vitamin D?

Abstract. Vitamin D deficiency is associated with a decreased insulin release, insulin resistance and type 2 diabetes in experimental and epidemiological studies. Animal studies show that 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3) stimulates the pancreatic β-cell to secrete insulin.

How can I lower my glucose level?

How to lower high blood sugar — naturallyLeave sugary beverages on the shelf. Sugar-sweetened beverages are a one-way ticket to high blood sugar. ... Be carb smart. ... Eat balanced meals. ... Get moving. ... Bust your stress. ... Be a glucose detective. ... Quit smoking.

What is the role of vitamin D in the synthesis of insulin?

Vitamin D enters the beta cell and interacts with several types of receptors, which bind together and essentially activate the insulin gene, increasing the synthesis of insulin.

What is the role of beta cells in diabetes?

Beta cells play a central role in insulin secretion. Gradual beta cell dysfunction is the biggest culprit of type 2 diabetes for approximately 60 percent of people diagnosed, according to a 2016 study published in Diabetes Care. Trusted Source. .

Does vitamin D affect insulin production?

If too little vitamin D impairs the body’s ability to manage calcium levels, it inevitably impairs the body’s ability to produce insulin .

Is too much vitamin D bad for you?

Becker also points to a study reported on by Healthline warning of the dangers of consuming too much vitamin D. “And yes, vitamin D helps your body take up calcium, but too much calcium is not good either.”. Smith agrees. “Caution should be taken with vitamin D dosages, for people with or without diabetes,” said Smith.

Is vitamin D good for diabetes?

While experts in diabetes care validate a genuine link between diabetes and vitamin D, there is no clear consensus on the effectiveness of supplements. Getty Images

Does vitamin D increase insulin sensitivity?

Through the same receptors associated with vitamin D’s impact on insulin secretion, vitamin D stimulates receptors that affect insulin sensitivity. Through a complicated physiological process, the interaction and binding with these receptors actually increase the number of total insulin receptors present in the body.

Clinical Understanding of Vitamin D

There are two main forms of vitamin D: ergocalciferol (vitamin D 2) and cholecalciferol (vitamin D 3 ). Vitamin D 2 is synthesized by plants (mainly mushrooms and yeast), whereas vitamin D 3 is synthesized in skin when it is exposed to ultraviolet B rays from sunlight. Vitamin D 3 is also found in a few foods such as fatty fish. 30

Treatment of Vitamin D Deficiency

The two forms of vitamin D supplements are D 2 (ergocalciferol) and D 3 (cholecalciferol). Both increase vitamin D in the blood. Vitamin D supplements are readily available, inexpensive, easy to administer, and safe. At high doses, vitamin D 2 may be less potent than vitamin D 3.

Vitamin D and Diabetes

Vitamin D deficiency and diabetes have one major trait in common: both are pandemic. The International Diabetes Federation estimates the number of people with diabetes worldwide to be nearly 285 million, or 7% of the world's population. 44 This number is expected to exceed 435 million by 2030.

Mechanisms of action

There is growing evidence that vitamin D deficiency could be a contributing factor in the development of both type 1 and type 2 diabetes. First, the β-cell in the pancreas that secretes insulin has been shown to contain VDRs as well as the 1 alpha hydroxylase enzyme.

Vitamin D and type 2 diabetes

After conducting a meta-analysis and review of the impact of vitamin D and calcium on glycemic control in patients with type 2 diabetes, Pittas et al. 50 concluded that insufficient vitamin D and calcium appears to hinder glycemic control and that supplementing both nutrients may be necessary to optimize glucose metabolism.

Vitamin D and type 1 diabetes

Observational studies also suggest that low vitamin D status may be associated with an increased risk of type 1 diabetes. For example, there is a greater incidence of type 1 diabetes related to geographic variation, with locations at higher latitudes having more type 1 diabetes.

Summary and Conclusion

Although the role of vitamin D in helping to regulate blood glucose remains poorly understood, vitamin D status appears to play a role in the development and treatment of diabetes. It is possible that optimal levels of serum vitamin D may be different for people at risk for developing diabetes, those with diabetes, and those without diabetes.

What is vitamin D?

This is due, in part, to the wide-reaching physiological functions of vitamin D; for instance, vitamin D is involved in cell growth, bone maintenance, neuromuscular activity, and the immune system. Also, importantly for this study, it has been implicated in inflammation.

Why is vitamin D called the sunshine vitamin?

Vitamin D is often referred to as the sunshine vitamin because it is created in our skin in response to direct sunlight. Previous studies have found a connection between low vitamin D levels and a higher risk of diabetes, but the mechanisms involved have been challenging to unravel.

Why is type 2 diabetes rising?

The condition is caused by faulty beta cells in the pancreas. These cells manufacture and release insulin, the hormone essential for controlling glucose levels in the blood.

Does vitamin D help with diabetes?

A new study investigates whether vitamin D might provide a new route to treatment. Boosting vitamin D’s activity might, eventually, help to battle diabetes. Currently, there are around 30 million people in the United States living with type 2 diabetes, a lifelong condition that cannot yet be cured. Obesity, one of the major risk factors, is ...

Does iBRD9 bring glucose levels back down?

They demonstrated that, in a mouse model of diabetes, iBRD9 brought glucose levels back down into the normal range.

Does vitamin D protect beta cells?

They identified a way in which vitamin D might protect beta cells. It seems to involve transcription, or how genes are decoded to produce proteins. The introduction of iBRD9 caused genes with a protective effect to be transcribed at higher rates, protecting the beta cells.

How does vitamin D affect insulin sensitivity?

There are several ways in which vitamin D could affect insulin sensitivity. 1,25(OH)2D appears to stimulate the expression of insulin receptors, which in turn will affect insulin sensitivity. [22–25] 1,25(OH)2D enters insulin-responsive cells and interacts with the VDR activating the VDR-retinoic acid X-receptor (RXR) complex which binds to a vitamin D response element found in the human insulin receptor gene promoter region.( Figure 2) The result is an enhanced transcriptional activation of the insulin receptor gene increasing the total number of insulin receptors without altering their affinity. 1,25(OH)2D may also enhance insulin sensitivity by activating peroxisome proliferator-activated receptor delta (PPAR-δ), which is a transcription factor that regulates the metabolism of fatty acids in skeletal muscle and adipose tissue [26]. Vitamin D has also been found to improve muscle oxidative phosphorylation after exercise. Another potential effect of 1,25(OH)2D on insulin sensitivity might be exerted viaits regulatory role in extracellular calcium concentration and flux through cell membranes. Calcium is essential for insulin-mediated intracellular processes in insulin-responsive tissues such as muscle and fat [27, 28], with a narrow range of intracellular calcium needed for optimal insulin-mediated functions [29]. Changes in intracellular calcium in insulin target tissues may contribute to peripheral insulin resistance [29–36] viaan impaired insulin signal transduction [36, 37] leading to a decreased glucose transporter activity. [36–38] Hypovitaminosis D also leads to an increase in the levels of parathyroid hormone (PTH), which has been associated with insulin resistance. [39, 40] Vitamin D may also affect insulin resistance indirectly through the renin-angiotensin-aldosterone system (RAAS), as described below. Finally, vitamin D insufficiency has been associated with increased fat infiltration in skeletal muscle, which appears independent of body mass and is thought to contribute to a decreased insulin action. [41]

Where is vitamin D3 found?

During exposure to solar UVB radiation, 7-dehydrocholesterol in the skin is converted to pre-vitamin D3, which is immediately converted to vitamin D3 in a heat-dependent non-enzymatic process. Excessive exposure to sunlight degrades pre-vitamin D3 and vitamin D3 into inactive phyto-products (photo-degradation), avoiding vitamin D toxicity in the setting of excess sunlight. Vitamin D3 is also found is certain foods, such as fatty fish. Vitamin D2 is synthesized by plants and is found mostly in nutrients supplemented with vitamin D (e.g. milk) or dietary supplements. Whether endogenously synthesized or ingested through diet or supplements, vitamin D in the circulation is bound to the vitamin D-binding protein (DBP), which transports it to the liver, where vitamin D is converted by vitamin 25-hydroxylase to 25-hydroxyvitamin D [25OHD]. This form of vitamin D is biologically inactive and must be converted primarily in the kidneys by 25-hydroxyvitamin D-1alpha-hydroxylase to the biologically active form, 1,25-dihydroxyvitamin D [1,25(OH)2D]. The presence of 1-alpha-hydroxylase in extra-renal tissues suggest that vitamin D may have important role beyond the musculo-skeletal system. 25-hydroxyvitamin D is the major circulating form of vitamin D and is an excellent biomarker of exposure, either from cutaneous synthesis or dietary intake. Blood concentration of 25OHD is used by clinicians as a biomarker to determine vitamin D status.

Is vitamin D inversely associated with diabetes?

There are many cross-sectional observational studies that have examined the association between vitamin D and type 2 diabetes and most have reported an inverse association between vitamin D status (25OHD concentration) and pre valent diabetes. One of the largest such cohorts is the National Health and Nutrition Examination Survey (NHANES) in United States, which reported an inverse association between 25OHD concentration and prevalence of diabetes in non-Hispanic whites and Mexican-Americans, but not African-Americans.[49] Similarly, this inverse association was seen in other large cohorts from the U.S.[40], Europe[50] and China.[51] The major limitation of cross-sectional studies is the potential of reverse causation; therefore, causality cannot be established.

Is vitamin D a risk modifier for diabetes?

Recently, vitamin D has risen as a potential diabetes risk modifier.

Does vitamin D affect beta cells?

Many effects of vitamin D on the pathophysiology of type 1 diabetes have been described, including changes in the immune-mediated destruction , [90] but also the beta-cell itself. The latter effect may , at least in part , be mediated indirectly by the effect of vitamin D on calcium homeostasis.

Is vitamin D a biomarker?

25-hydroxyvitamin D is the major circulating form of vitamin D and is an excellent biomarker of exposure, either from cutaneous synthesis or dietary intake.

Does sunlight degrade vitamin D3?

Excessive exposure to sunlight degrades pre-vitamin D3 and vitamin D3 into inactive phyto-products (photo-degradation), avoiding vitamin D toxicity in the setting of excess sunlight. Vitamin D3 is also found is certain foods, such as fatty fish.

What is the role of vitamin D in diabetes?

Vitamin D maintains the normal resting levels of both Ca2+and ROS that are elevated in the β-cells during diabetes. Vitamin D also has a very significant role in maintaining the epigenome. Epigenetic alterations are a feature of diabetes by which many diabetes-related genes are inactivated by hypermethylation.

How does vitamin D affect insulin?

Vitamin D deficiency has been linked to the onset of diabetes. This review summarizes the role of Vitamin D in maintaining the normal release of insulin by the pancreatic beta cells (β-cells). Diabetes is initiated by the onset of insulin resistance. The β-cells can overcome this resistance by releasing more insulin, thus preventing hyperglycaemia. However, as this hyperactivity increases, the β-cells experience excessive Ca2+and reactive oxygen species (ROS) signalling that results in cell death and the onset of diabetes. Vitamin D deficiency contributes to both the initial insulin resistance and the subsequent onset of diabetes caused by β-cell death. Vitamin D acts to reduce inflammation, which is a major process in inducing insulin resistance. Vitamin D maintains the normal resting levels of both Ca2+and ROS that are elevated in the β-cells during diabetes. Vitamin D also has a very significant role in maintaining the epigenome. Epigenetic alterations are a feature of diabetes by which many diabetes-related genes are inactivated by hypermethylation. Vitamin D acts to prevent such hypermethylation by increasing the expression of the DNA demethylases that prevent hypermethylation of multiple gene promoter regions of many diabetes-related genes. What is remarkable is just how many cellular processes are maintained by Vitamin D. When Vitamin D is deficient, many of these processes begin to decline and this sets the stage for the onset of diseases such as diabetes.

How does vitamin D help with hypermethylation?

Vitamin D acts to prevent such hypermethylation by increasing the expression of the DNA demethylases that prevent hypermethylation of multiple gene promoter regions of many diabetes-related genes. What is remarkable is just how many cellular processes are maintained by Vitamin D.

Does vitamin D cause diabetes?

Vitamin D deficiency has been linked to the onset of diabetes. This review summarizes the role of Vitamin D in maintaining the normal release of insulin by the pancreatic beta cells (β-cells). Diabetes is initiated by the onset of insulin resistance. The β-cells can overcome this resistance by relea …

What vitamins are needed for type 2 diabetes?

Other common supplements. Here’s what you need to know about other common supplements: A B12 supplement can be helpful if you have type 2 diabetes and are deficient in the vitamin. People who take metformin for type 2 diabetes have lower levels of vitamin B12.

Does cinnamon help with neuropathy?

Enjoy a sprinkling of cinnamon on oatmeal instead of taking supplements. Alpha-lipoic acid (ALA) reduces pain from diabetic neuropathy. ALA injections, which are available only in Europe, improve symptoms of neuropathy in the short term. Results are mixed with oral supplements, which are available in the United States.

Can chromium cause high blood sugar?

A chromium deficiency may lead to high blood sugar levels. It may be worth a try if you’re deficient in chromium, but that’s very rare. Steer clear if you’ve been diagnosed with kidney disease. Chromium supplements might further damage the kidneys and worsen the disease. Vitamin E & St. John’s Wort.

Does niacin raise cholesterol?

Niacin. Some people take niacin to raise HDL (“good”) cholesterol, but it can also affect your diabetes management. Niacin raises fasting glucose levels (your blood sugar levels when you are not eating) for people with diabetes, meaning the risks may outweigh the benefits.

Can supplements affect blood sugar?

Supplements that impact blood sugar. Supplement s may cause unwelcome—or dangerous—side effects, especially if they interact with your medications. While some ingredients could intensify the effects of your diabetes meds, causing hypoglycemia (low blood sugar, also called blood glucose), others may have the opposite effect, ...

Do vitamins and minerals have the same effect in the body?

It’s not clear whether vitamins and minerals have the same effect in the body when taken in supplement form. If you have a true vitamin deficiency, however, a supplement may be helpful. Americans are most commonly deficient in vitamins D and B12, calcium, and iron.

Is vitamin D good for diabetes?

The jury’s still out on vitamin D. There is an association between higher concentrations of vitamin D in the blood during childhood and a lower risk of type 1 diabetes. More research is needed to understand the link, but here’s one thing experts can agree on: if you’re deficient in vitamin D, a supplement can help.

What is the best vitamin for diabetes?

Taking a Vitamin E supplement can help prevent premature aging and cell damage, decreasing the likelihood of developing type 2 diabetes, and it helps to maintain good blood sugars in people with existing diabetes. Excellent sources of Vitamin E include almonds, sunflower seeds, nut butter, hazelnuts, avocado, and fresh salmon.

How to get vitamin D levels up?

Many people with diabetes also have low levels of Vitamin D, so make sure to supplement your diet with plenty of egg yolks, liver, fish, and dairy products with the nutrient added. Regular sun exposure (for between 10-30 minutes a day) can also help you achieve higher Vitamin D levels.

Why is B12 important for diabetics?

Vitamin B12 is vital for the health of red blood cells and brain function. People with diabetes who suffer from nerve damage in their hands and feet may see their symptoms worsen if they have a vitamin B12 deficiency. Studies have shown that long-term use of the diabetes drug Metformin can lead to a vitamin B12 deficiency.

Why is it important to take vitamins?

Vitamins simply help people supplement their diets, especially if they struggle to eat enough fruits and vegetables, and vitamins are crucial to living a healthy life if you have a chronic condition, such as diabetes. It’s important to always talk to your doctor, who may order blood work, to see if you have any vitamin deficiencies.

What to do if you have vitamin deficiencies?

It’s important to always talk to your doctor, who may order blood work, to see if you have any vitamin deficiencies. Working together with your care team, you can choose the best supplementation for you and your lifestyle.

Does vitamin C help with diabetes?

Many people with diabetes suffer from low Vitamin C levels. Increasing one’s intake of Vitamin C helps control the levels of sorbitol in the blood, which can be harmful at high levels and may contribute to retinopathy and kidney damage, which are common complications of diabetes.

Can low vitamin D cause diabetes?

Vitamin D. Vitamin D deficiencies are linked to the development of diabetes, and a study from Denmark showed that chronic low levels of Vitamin D in people with diabetes can lead to increased risk of complications and death. Many people with diabetes also have low levels of Vitamin D, so make sure to supplement your diet with plenty of egg yolks, ...

What are the benefits of taking vitamins and minerals for diabetes?

Vitamins and Minerals for diabetes helps in regulating blood sugar and insulin sensitivity. Vitamins and Minerals for diabetes helps in maintaining healthy skin, eyes, teeth, bones, brain, muscles and other things. Multivitamins for diabetes prevent nutrient deficiencies and symptoms associated with it.

Why is vitamin C low in diabetics?

Vitamin C is needed as one of the best vitamins for diabetics’ type 1 because it helps to regulate the blood glucose and lipid levels.

Why is it important to take a multivitamin daily?

Taking a multivitamin daily serves health insurance for us as it gives a daily guarantee of the essential vitamins and minerals needed. Multivitamins give us the whole nutrient in one supplement without having to worry about anything throughout the day. Also, taking the right multivitamin gives us more energy, healthy hair, puts us in a good mood and a clearer mind.

Why are vitamins important?

Vitamins are very essential to our bodies as they contribute to growth, nerve function, digestion, and a whole host of other things. There are studies which prove that multivitamin doesn’t reduce the risk of heart and cardiovascular disease s while some said it does reduce the risk of heart diseases, same also with some vitamin supplements that can help to improve the memory.

What is in a diabetic pack?

The nutrients in this health pack include vitamins, minerals, lutein, green tea, and alpha-lipoic acid, it also includes vitamin E which is the best supplement for energy and a healthy heart. It also keeps the immune system healthy which is very much needed for diabetics as they often suffer from a weak immune system.

What is the cause of Type 1 diabetes?

Type 1 diabetes is a kind of severe condition caused by the inability of the pancreas to produce insulin. Insulin is responsible for controlling the production of energy by regulating the amount of sugar in glucose from entering the body.

Is taking a supplement bad for diabetics?

What makes a supplement bad for diabetics is the side effect and a lot of supplements has helped to curb the danger of diabetes although supplement should not be used to replace the standard diabetes treatment, this is why it is important to talk to your doctor before using any supplements as some of the product can meddle with other treatments or medications being used. Failure to talk to your doctor might lead to you putting your life at risk; natural product most times doesn’t guarantee safety.

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