
- Gastric acidifiers, these are the drugs which are use to restore temporarily the acidity of stomach in patient suffering from hypochlorhydria
- Urinary acidifiers, used to control pH in urine
- Systemic acidifiers, used to control pH in the overall body
- Acids, mostly used in laboratory experiments
What are acidifiers?
Acidifiers are inorganic chemicals that, put into a human (or other mammalian) body, either produce or become acid . These chemicals increase the level of gastric acid in the stomach when ingested, thus decreasing the stomach pH . Out of many types of acidifiers, the main four are:
What are gastric acidifiers used to treat?
Gastric acidifiers, these are the drugs which are used to restore temporarily the acidity of stomach in patient suffering from hypochlorhydria Patients who suffer from achlorhydria have deficient secretion of hydrochloric acid in their stomach. In such cases, acidifiers may provide sufficient acidity for proper digestion of food.
What is the role of acidifiers in animal gut health?
Among these alternatives, the organic acids or simply acidifiers play an important role in gut health in animals. The acidifiers could be used to favourably manipulate the intestinal microbial populations and improve the immune response, hence perform an activity similar to antibiotics in food animals in countering pathogenic bacteria.
Why do formulators use acidifiers to control microbes?
In these products, as in many others, formulators long have relied on acidifiers to control microbes. As a product's pH is lowered, the amount of an organic acid in its undissociated form increases. The undissociated forms have the greatest ability to keep microbial growth under control.

What are urinary acidifiers and for what purpose are they used?
Ammonium chloride (brand names: UriKare®, Uroeze®, Acidax®) is a urine acidifier used to treat metabolic alkalosis, dissolve certain types or urinary stones (struvite stones), treat certain toxicities, or increase the effectiveness of certain antimicrobials.
What are acidifiers with example?
Acidifiers are compounds classified as organic or inorganic acids. Organic acids include formic, fumaric, lactic, benzoic, propionic, and citric acids. Inorganic acids include hydrochloric, sulfuric, and phosphoric acids.
What is the difference between acidifiers and antacids?
Acidifiers are used antibacterial agent such as formic acid, acetic acid, lactic acid etc. Dilute HCL is used as acidifying agent. Antacids: Definition: An antacid is a substance which neutralizes stomach acidity which in turn relieves heart burn in digestion or stomach upset.
Which drug is used as acidifier?
The ammonium ion (NH4+) in the body plays an important role in the maintenance of acid-base balance. The kidney uses ammonium (NH4+) in place of sodium......Acidifying Agents.DrugTargetTypeCalcium chlorideProtein S100-A13target
What is acidifier in poultry?
Organic acids as feed and drinking water acidifiers for poultry. Organic acids are organic compounds that contain a carboxyl group (-COOH). The carboxyl group dissociates in solution releasing a proton, thus giving the compound acidic properties (Voet and Voet, 1995).
What is meant by acidifier?
Definition of acidifier : one that acidifies especially : a substance used to increase soil acidity.
How many types of acidifiers are there?
These are many types of acidifiers but the main four types are: Gastric Acidifiers. Urinary Acidifiers. Systemic Acidifiers.
What are acidifying agent in pharmacy?
Urinary acidifying agents are medications used to dissolve certain types of stones in the kidney and bladder and to maintain acid-base balance in blood and urine. Urinary acidifying agents chemically make the stones more soluble and facilitate their excretion or removal.
Is calcium an Acidifier?
An alternative acidifying agent is calcium chloride (2 mEq/kg of body weight orally), which gives results similar to ammonium chloride. It can be used in patients who cannot tolerate ammonium chloride due to nausea and vomiting or in patients with liver disease in whom ammonium chloride is contraindicated.
What is example of acidifying agent?
GI acidifying agents (e.g., guanethidine, reserpine, ascorbic acid, fruit juices) lower absorption of amphetamines.
Acidifier Definition & Meaning - Merriam-Webster
Overview of acid-base and electrolyte disorders - Summary of relevant ...
Acidifiers - Therapeutic Classification - Medindia
Acidifier - an overview | ScienceDirect Topics
Why are acidifiers used in pigs?
Acidifiers are believed to enhance growth performance via pH reduction in the digestive tract, which improves nutrient digestibility and promotes growth of beneficial bacterial while inhibiting pathogenic bacteria (Jacela et al., 2009a). Acidifiers have been commonly targeted for weanling pigs.
Why do sows need acidifiers?
In sows, use of acidifiers in the diet improves nutrient digestibility and reduces urinary pH, which aids in controlling the incidence of urinary tract infections (Kluge et al., 2010).
What are the different types of acids?
Organic acids include formic, fumaric, lactic, benzoic, propionic, and citric acids. Inorganic acids include hydrochloric, sulfuric, and phosphoric acids. Salts of acids also have been used as acidifiers, including calcium-formate, potassium-diformate, sodium-diformate, and sodium-fumarate.
Do acidifiers contain fatty acids?
In addition, some commercial acidifiers contain protected acids that are coated with fatty acids or other molecules, mainly to allow the release of the acid in a targeted location in the gut with the goal to improve effectiveness (Upadhaya et al., 2014).
Can inorganic acids be used as an alternative to organic acids?
However, inorganic acids have been often considered as an alternative to organic acids because of lower cost. Acidifiers may also benefit grow-finish pigs (Tung and Pettigrew, 2006), particularly under transition or stressful conditions.
What are the functions of acidifiers?
Depending on the ingredient and the product matrix into which it is placed, acidifiers have the ability to enhance, mask and contribute to flavor profiles. Balancing a product's sweetness and sourness throughout a taste experience is important. (See chart.) Acids differ in terms of how long sourness lingers.
Which acid is best for sourness?
“In applications with aspartame, sucralose, and neotame, all of which have prolonged sweetness, malic or lactic acid is best since they also have a more persistent sourness,” says Sortwell.
What happens to an organic acid when its pH is lowered?
As a product's pH is lowered, the amount of an organic acid in its undissociated form increases. The undissociated forms have the greatest ability to keep microbial growth under control. Some organic acids, such as benzoic and sorbic acid, are extremely effective microbial inhibitors and are considered “preservatives.”.
Molecularly Imprinted Polymers
Håkan S. Andersson, Ian A. Nicholls, in Techniques and Instrumentation in Analytical Chemistry, 2001
Citric Acid
Hadi Poerwono, ... Harry G. Brittain, in Analytical Profiles of Drug Substances and Excipients, 2001
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Justin Salminen, ... Anne Ojala, in Thermodynamics, Solubility and Environmental Issues, 2007
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Enzyme-based amperometric biosensors for malic acid – A review
Christopher J. Matthews, ... Wayne M. Patrick, in Analytica Chimica Acta, 2021
Drugs used to treat Urinary Acidification
The following list of medications are in some way related to, or used in the treatment of this condition.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
