what are examples of monoamine oxidase inhibitors

Full Answer

What are MAOI drugs list?

• Harmala alkaloids (found in Coffee, Syrian rue, Passion flower, Ayahuasca, Tribulus terrestris and Tobacco) Harmine, Harmaline, Tetrahydroharmine, Harmalol, Harman, Norharman, etc.
• Piperine (found in Pepper has a 1.85 fold selectivity for MAOA over MAOB)
• Resveratrol (found in Japanese knotweed and skin of red grapes)

What drugs contain MAOI inhibitors?

MAOI inactivation of this enzyme results in a greater amount of active neurotransmitters throughout the brain, which, over time, can lead to functional brain changes and a subsequent improvement in depression symptoms. 1. Examples of MAOIs include: 2. Isocarboxazid (Marplan). Phenelzine (Nardil). Selegiline (Emsam). Tranylcypromine (Parnate).

What is MAOI inhibitor list?

• Iproniazid (Marsilid, Iprozid, Ipronid, Rivivol, Propilniazida) (available in France)
• Isocarboxazid (Marplan)
• Hydracarbazine
• Phenelzine (Nardil, Nardelzine)

What are the side effects of MAOI inhibitors?

The most common side effects of MAOIs include:

• Dry mouth
• Nausea, diarrhea or constipation
• Headache
• Drowsiness
• Insomnia
• Dizziness or lightheadedness
• Skin reaction at the patch site

What is most commonly prescribed MAOI?

The four most commonly prescribed MAOIs are selegiline, isocarboxazid, phenelzine, and tranylcypromine.

What do monoamine oxidase inhibitors do?

Monoamine oxidase inhibitors (MAOIs) are a class of drugs that were developed in the 1950s. They're quite effective in treating depression, panic disorder, and other anxiety disorders.

What are examples of monoamine?

The monoamine neurotransmitters include serotonin, dopamine, and norepinephrine.

What are natural MAO inhibitors?

The findings in this study yield evidence to suggest there are a number of natural products commonly used worldwide which have capacity to inhibit human MAO-B enzyme. However, in the therapeutic range, the most likely candidates were Amur Cork tree, Licorice, Psoralea Fruit and Bakuchi.

Is Xanax an MAO inhibitor?

But they are not be taken with maois work by maois were the united states. Xanax and. Lexapro is inhibited by sudafed, norepinephrine, so xanax is unknown, must be used to the central nervous system, it is unknown, heart, please help.

What are the 4 monoamines?

The monoamines are neuromodulators derived from single amino acids (figure 1). The major representatives of the monoamines that are known to modulate well-defined behaviors are dopamine, noradrenaline, octopamine, and serotonin.

Is Zoloft an SSRI or MAOI?

Zoloft comes from a class of antidepressant drugs known as SSRIs (selective serotonin reuptake inhibitors). Other SSRIs include Paxil, Prozac, Symbyax, Lexapro and Celexa. SSRIs control depression and other mental illnesses and have been around since the early 1980s.

Is Prozac a MAO inhibitor?

Prozac is the brand name of the drug fluoxetine, a selective serotonin reuptake inhibitor (SSRI). SSRIs are second-generation antidepressants, which means they are newer than first-generation medications such as monoamine oxidase inhibitors (MAOIs) or tricyclic antidepressants (TCAs).

What does a MAO inhibitor inhibit quizlet?

MAO degradation of monoamines helps regulate neurotransmitter stores at the nerve terminal, therefore MAO inhibition results in elevated synaptic neurotransmitter levels.

What is the difference between an SSRI and an MAOI?

Although SSRIs are the current frontline treatment for depression, monoamine oxidase inhibitors (MAOIs) were the first antidepressants developed. They are typically more potent than SSRIs because they affect more neurotransmitters, and they can cause more side effects.

What is the function of monoamine oxidase in neurons?

The main role for the monoamine oxidase (MAOA) enzyme is thought to be in degrading serotonin following its reuptake from the synaptic cleft, although it is also capable of degrading both norepinephrine and dopamine.

Does MAO break down dopamine?

Monoamine Oxidase (MAO) regulates levels of monoamines (such as dopamine and norepinephrine) by breaking them down — either after reuptake, or in the synaptic cleft (Nolte 1993).

What Are Monoamine Oxidase Inhibitors Used for?

MAOIs may be used to treat the symptoms of depression, such as sadness, anxiety, or worry, that have not responded to other antidepressants. They s...

What Are The Differences Between Monoamine Oxidase Inhibitors?

All three MAOIs (isocarboxazid, phenelzine and tranylcypromine), available in the U.S. and used for the treatment of depression, are irreversible i...

Are Monoamine Oxidase Inhibitors Safe?

When taken at the recommended dosage, MAOIs are considered safe. However, they are potentially fatal in overdose and have also been associated with...

What Are The Side Effects of Monoamine Oxidase Inhibitors?

One of the more common side effects associated with MAOIs on drug initiation is low blood pressure when going from a standing to a sitting position...

MAOIs Approved to Treat Depression

The Food and Drug Administration (FDA) has approved these MAOIs to treat depression: 1. Isocarboxazid (Marplan) 2. Phenelzine (Nardil) 3. Selegilin...

Safety Concerns With MAOIs

Consider these issues and discuss them with your doctor before taking an MAOI: 1. Antidepressants and pregnancy. Some antidepressants may harm your...

Suicide Risk and Antidepressants

Most antidepressants are generally safe, but the FDA requires that all antidepressants carry black box warnings, the strictest warnings for prescri...

Stopping Treatment With MAOIs

Talk to your doctor before you stop taking an MAOI. Stopping treatment with MAOIs has been associated with flu-like symptoms, including anxiety, ag...

Finding The Right Antidepressant

Each person reacts differently to a particular antidepressant and may be more likely to have certain side effects. Because of this, one antidepress...

Why are MAOIs used when other antidepressants don't work?

Because of side effects and safety concerns, MAOIs are most often tried when other antidepressants don't work.

What are MAOIs used for?

MAOIs are sometimes used to treat conditions other than depression, such as Parkinson's disease.

What enzyme is responsible for removing dopamine from the brain?

An enzyme called monoamine oxidase is involved in removing the neurotransmitters norepinephrine, serotonin and dopamine from the brain. MAOIs prevent this from happening, which makes more of these brain chemicals available to effect changes in both cells and circuits that have been impacted by depression.

What happens if you stop MAOI?

If you stop an MAOI suddenly, you're more likely to experience a withdrawal-type reaction, sometimes called discontinuation syndrome. Rarely, uncommon withdrawal symptoms such as confusion, detachment from reality (psychosis) and convulsions can occur.

Can MAOIs be taken with food?

Use of MAOIs typically requires diet restriction s and avoid ing certain other medications because MAOIs can cause dangerously high blood pressure when taken with certain foods or medications.

Can MAOIs cause allergic reactions?

Drug interactions. MAOIs can cause serious reactions when you take them with certain medications, such as other antidepressants, certain pain drugs, certain cold and allergy medications, and some herbal supplements.

Can MAOI cause high serotonin levels?

Rarely, an MAOI can cause dangerously high levels of serotonin, known as serotonin syndrome. It most often occurs when two medications that raise serotonin are combined. These include, for example, other antidepressants, certain pain or headache medications, and the herbal supplement St. John's wort.

What is the role of monoamine oxidase inhibitors?

Monoamine oxidase inhibitors are responsible for blocking the monoamine oxidase enzyme. The monoamine oxidase enzyme breaks down different types of neurotransmitters from the brain: norepinephrine, serotonin, dopamine, and tyramine. MAOIs inhibit the breakdown of these neurotransmitters thus, increasing their levels and allowing them to continue to influence the cells that have been affected by depression. [6]

When were monoamine oxidase inhibitors first introduced?

Monoamine oxidase inhibitors (MAOIs) were first introduced in the 1950s. [1][2]They are a separate class from other antidepressants, treating different forms of depression as well as other nervous system disorders such as panic disorder, social phobia, and depression with atypical features.[3] Examples of atypical features are oversleeping and overeating. Even though MAOIs were the first antidepressants introduced, they are not the first choice in treating mental health disorders due to several dietary restrictions, side effects, and safety concerns. MAOIs are only a treatment option when all other medications are unsuccessful.

Why should MAOI be avoided?

Safety and optimal treatment are vital to patient health. Patients with a history of seizures or epilepsy should avoid MAOIs; these medications can increase the occurrence of seizures. Also, people with a history of alcoholism, angina, severe headaches, blood vessel disease, diabetes, kidney or liver disease, history of a recent heart attack or stroke, overactive thyroid, and pheochromocytoma should not receive MAOI therapy; since this may cause a hypertensive crisis.[2] This caution is also necessary for patients with a family history of depression, any neurological disorders, or even if any family members have attempted suicide. Due to the high risks, patients must provide a complete family history. Educating the patient on the importance of possible risks and side effects of the drug is critical for their well-being. It provides them an opportunity for a better outcome.

What foods can cause tyramine?

Examples of high levels of tyramine in food are types of fish and types of meat, including sausage, turkey, liver, and salami. [15][16]Also, certain fruits can contain tyramine, like overripe fruits, avocados , bananas, raisins , or figs. Further examples are cheeses, alcohol, and fava beans; all of these should be avoided even after two weeks of stopping MAOIs.[16] Anyone taking MAOIs is at risk for an adverse hypertensive reaction, with accompanying morbidity.

Where is monoamine oxidase found?

There are two types of monoamine oxidase, A and B. The MAO A is mostly distributed in the placenta, gut, and liver, but MAO B is present in the brain, liver, and platelets.  Serotonin and noradrenaline are substrates of MAO A, but phenylethylamine, methylhistamine, and tryptamine are substrates of MAO B. Dopamine and tyramine are metabolized by both MAO A and B. Selegiline and rasagiline are irreversible and selective inhibitors of MAO type B, but safinamide is a reversible and selective MAO B inhibitor. [7]

Can MAOIs cause lightheadedness?

Furthermore, if applied via patch, a skin reaction may occur at the patch site.[9] Recommendations are that any patient scheduled for an elective surgery that requires general anesthesia should not take MAOIs for at least ten days before the surgery to avoid any drug interaction. [10][11]

Can MAOIs cause serotonin?

MAOIs can potentially cause drug-to-drug interactions, drug-food interaction, and overdoses, of which the patient should be aware.[9] For example, patients should not be mixing MAOIs with other antidepressants like selective serotonin reuptake inhibitors (SSRIs).[12] These two drugs combined can cause serotonin syndrome, which is potentially fatal. The first cases of serotonin syndrome were reported during the 1960s when patients were on MAOIs and tryptophan. Patients showed signs and symptoms of fever, confusion, increased perspiration, muscle rigidity, seizures, liver or kidney problems, fluctuation of heart rhythms, and blood pressure. Furthermore, when changing MAOIs to another antidepressant, patients should give themselves 14 days to pass before initiating the new treatment, to prevent any drug interaction.

What is a reversible inhibitor of monoamine oxidase A?

Reversible inhibitors of monoamine oxidase A ( RIMAs) are a subclass of MAOIs that selectively and reversibly inhibit the MAO-A enzyme. RIMAs are used clinically in the treatment of depression and dysthymia.

What is MAO inhibitor?

Monoamine oxidase inhibitors ( MAOIs) are a class of drugs that inhibit the activity of one or both monoamine oxidase enzymes: monoamine oxidase A (MAO-A) and monoamine oxidase B (MAO-B). They are best known as highly efficacious anti-depressants, as well as effective therapeutic agents for panic disorder and social phobia. They are particularly effective in treatment-resistant depression and atypical depression. They are also used in the treatment of Parkinson's disease and several other disorders.

What is the best treatment for Parkinson's disease?

Newer MAOIs such as selegiline (typically used in the treatment of Parkinson's disease) and the reversible MAOI moclobemide provide a safer alternative and are now sometimes used as first-line therapy.

What is the function of MAOIs?

MAOIs act by inhibiting the activity of monoamine oxidase, thus preventing the breakdown of monoamine neurotransmitters and thereby increasing their availability. There are two isoforms of monoamine oxidase, MAO-A and MAO-B. MAO-A preferentially deaminates serotonin, melatonin, epinephrine, and norepinephrine.

When did MAO inhibitors become popular?

The older MAOIs' heyday was mostly between the years 1957 and 1970. The initial popularity of the 'classic' non-selective irreversible MAO inhibitors began to wane due to their serious interactions with sympathomimetic drugs and tyramine -containing foods that could lead to dangerous hypertensive emergencies. As a result, the use by medical practitioners of these older MAOIs declined. When scientists discovered that there are two different MAO enzymes (MAO-A and MAO-B), they developed selective compounds for MAO-B, (for example, selegiline, which is used for Parkinson's disease), to reduce the side-effects and serious interactions. Further improvement occurred with the development of compounds ( moclobemide and toloxatone) that not only are selective but cause reversible MAO-A inhibition and a reduction in dietary and drug interactions. Moclobemide, was the first reversible inhibitor of MAO-A to enter widespread clinical practice.

What is MAO-B used for?

Inhibition of both MAO-A and MAO-B is used in the treatment of clinical depression and anxiety .

Why do people carry MAOI cards?

For this reason, many users carry an MAOI-card, which lets emergency medical personnel know what drugs to avoid (e.g. adrenaline (epinephrine) dosage should be reduced by 75%, and duration is extended.)

What are the two subtypes of monoamine oxidase inhibitors?

There are two common subtypes of monoamine oxidase inhibitors, MAO-A inhibitors and MAO-B inhibitors.

What are MAOI drugs?

Hydracarbazine: This is a compound with MAOI properties that is utilized primarily to lower blood pressure.

Why are MAOIs discontinued?

There are other MAOI drugs that have been withdrawn from the market due to adverse side effects. The majority of discontinued and problematic MAOIs are classified as “hydrazines.” The hydrazines are a group of non-selective MAOIs with irreversible inhibition properties. Most hydrazines were marketed throughout the 1950s and 1960s, but were withdrawn due to causing liver damage.

How does MAOI work?

Scientists eventually developed more selective MAOI drugs to reduce side effects and improve upon existing treatments. Monoamine oxidase inhibitors work by inhibiting activity of monoamine oxidase , which results in increased levels of various neurotransmitters (serotonin, norepinephrine, dopamine). These drugs have been proven effective ...

What is a MAOI?

MAOI List: Monoamine Oxidase Inhibitors. MAOIs (Monoamine Oxidase Inhibitors) are drugs that are considered “first-generation” antidepressants. This class of drugs was originally developed for the treatment of tuberculosis, but were found to have antidepressant properties when given to depressed patients. In the 1950s, they became very popular as ...

What is MAOI in depression?

This drug is an MAOI that acts as a reverse inhibitor on MAO-A. It was introduced to France in 1984 for depression. This drug tends to have activating properties and in many cases can increase levels of anxiety. Compared to the MAOI Moclobemide, this drug was found to have more side effects and be less effective.

When was Benmoxin created?

Benmoxin: This was an irreversible non-selective MAOI that was created in 1967 and was utilized as an antidepressant throughout Europe. It belonged in the hydrazine class of drugs and was eventually discontinued from the market.

How long do you have to be off MAOI before taking another medication?

MAOIs can interact with a lot of other medications, which makes them hard to use alongside other medications. (You generally need to be off an MAOI for about 2 weeks before starting another antidepressant.) They can also trigger allergic reactions to certain foods, so being on them often involves dietary restrictions.

Can MAOIs be used for Parkinson's?

Still, MAOIs can be helpful if other types of antidepressants haven’t worked. They are sometimes used to treat bipolar disorder, or to treat neurological conditions such as Parkinson’s disease.

What is monoamine oxidase inhibitor?

Monoamine oxidase inhibitors are a class of drugs primarily used as antidepressants. Their use has waned over the last several decades due to the availability of other medications for depression, their side effects, and their interactions with food and drugs (which may require a special diet by those who take them). 1.

What is the name of the opioid that blocks norepinephrine?

Tramadol (an atypical opioid painkiller with norepinephrine reuptake blocking effects).

What Are MAOIs?

Monoamine oxidase inhibitors are a class of drugs primarily used as antidepressants. Their use has waned over the last several decades due to the availability of other medications for depression, their side effects, and their interactions with food and drugs (which may require a special diet by those who take them). 1

How does MAOI work?

MAOIs work by inhibiting the action of monoamine oxidase (MAO)—an enzyme involved in the metabolism and inactivation of a number of neurotransmitters in the brain, including norepinephrine, serotonin, and dopamine. MAOI inactivation of this enzyme results in a greater amount of active neurotransmitters throughout the brain, which, over time, ...

Can MAOIs cause tyramine to build up?

A dangerous interaction can occur when a patient on MAOIs eats foods rich in the amino acid tyramine. Normally, the monoamine oxidase enzyme keeps tyramine at safe levels in the body. But when the enzyme is inhibited by MAOIs, tyramine metabolism is inhibited, and the amino acid may build up to excessive levels.

Can MAOIs cause high blood pressure?

A dangerous interaction can occur when a patient on MAOIs eats foods rich in the amino acid tyramine. Normally, the monoamine oxidase enzyme keeps tyramine at safe levels in the body. But when the enzyme is inhibited by MAOIs, tyramine metabolism is inhibited, and the amino acid may build up to excessive levels. As levels of tyramine rise, a person can experience high blood pressure, headaches, heart problems, nausea, vomiting, visual problems, and confusion. 3

Is isocarboxazid a MAO inhibitor?

Iproniazid’s initial success ushered in an era of treatment with more powerful MAO inhibitors, such as isocarboxazid, tranylcypromine, and phenelzine. 8

What drugs inhibit MAOI?

Finally we come to the question as to what drugs act as specific antagonists to the syndromes. As stated earlier, neuroleptics inhibit the MAOI/L-dopa syndrome. In contrast the putative 5-HT antagonists are remarkably ineffective in inhibiting the MAOI/L-tryptophan responses. While methysergide and metergoline inhibit the hind-brain or spinally mediated behavioural changes (forepaw padding, head weaving, Straub tail hind-limb abduction) the hyperactivity and hyper-reactivity are not inhibited and indeed are enhanced with the animals showing bursts of locomotor activity ( Fig. 3, Deakin and Green, 1978 ). (-)-Propranolol on the other hand is able to inhibit all the behavioural changes seen while (+)-Propranolol is ineffective in inhibiting the syndrome ( Costain and Green, 1978; Deakin and Green, 1978; Green and Grahame-Smith, 1976b ).

What is the MAO in pargyline?

MAO represents monoamine oxidase.

Does methysergide block DA?

What complicated these observations considerably was the finding that methysergide and metergoline inhibit those components of the DA-syndrome which they block in the 5-HT-syndrome, namely, head weaving, hind limb abduction and forepaw treading ( Deakin and Green, 1978 ). Since we cannot demonstrate the involvement of 5-HT in the DA-syndrome, we must perhaps speculate that these drugs have effects not only on some 5-HT systems but also on DA-receptors.

Is racemic deprenyl a monoamine?

Racemic deprenyl, a monoamine–oxidase inhibitor used in the treatment of depression, is metabolized to (+)- and (−)-metamphetamine [96], the former being much more active than its (−)-isomer as central stimulant, leading to drug abuse ( Table 18.7 ).

Is MAOI a hind brain syndrome?

Jacobs and Klemfuss (1975) have suggested that many of the behaviour al components of the MAOI/L-tryptophan syndrome are hind-brain or spinally mediated and we would agree with this. Lesioning of the descending 5-HT pathways to the hind-brain and spinal cord with 5,7-dihydroxytryptamine results in degeneration of these tracts followed by post-synaptic receptor “supersensitivity” as first reported by Trulson and colleagues (1976). When these denervated animals are given the 5-HT agonist 5-MeODMT, many of the behavioural changes are enhanced ( Table 2) indicating the responses are produced by the “supersensitive” spinal receptors.

Does MAO inhibition matter?

It does not appear to matter which MAO inhibitor is used provided over 85% inhibition of both Type A and Type B MAO is produced. If only one form of the enzyme is inhibited the other form can apparently continue to metabolise the amine being formed. Without almost total MAO inhibition there is presumably still a large degree of intraneuronal metabolism by MAO and the amine does not “spill-over” from the nerve ending and produce a functional response; that is, the behavioural change ( Green and Youdim, 1975; Green and colleagues, 1977 ). This is presumably also why no behavioural changes are seen following administration of L-tryptophan or L-dopa alone, in doses up to 100 mg/Kg ( Grahame-Smith, 1971a ).

Is deprenyl a MAO inhibitor?

On the other hand, the (−)-isomer of deprenyl is a much more potent MAO-B inhibitor than the (+)-isomer. For these reasons, racemic deprenyl has been replaced by (−)-deprenyl in clinical practice. In the racemic local anesthetic prilocaïne ( Figure 18.8 ), only the R- (−)-isomer is metabolized to an aniline derivative (ortho-toluidine) and to the corresponding para- and ortho-aminophenols that are highly toxic and responsible for methemoglobinemia [97].

What is monoamine oxidase?

Understanding monoamine oxidase. Monoamine oxidase is a type of enzyme that helps neurons fire throughout your body. It’s formed in your liver and cleans up neurotransmitters in your brain once they’ve done their jobs. Besides neurotransmitters, monoamine oxidase cleans out tyramine, a chemical that helps regulate blood pressure.

What is the effect of monoamine oxidase on mood?

By inhibiting monoamine oxidase, MAOIs allow more of these neurotransmitters to remain in the brain, thus elevating mood through improved brain cell communication.

Why do people take MAOIs?

Because MAOIs inhibit monoamine oxidase from doing its job, they adversely affect blood pressure in addition to keeping neurotransmitters at optimal levels. People taking MAOIs have to pay special attention to their blood pressure, including avoiding certain foods.

What are MAOIs in the brain?

MAOIs work with the chemicals in your brain called neurotransmitters that allow brain cells to communicate with each other. Depression is thought to be caused by low levels of the neurotransmitters dopamine, serotonin, and norepinephrine, which collectively are called monoamines. A chemical found naturally in the body, monoamine oxidase, ...

How does MAO B work?

It works by selectively blocking monoamine oxidase B (MAO-B). This reduces the breakdown of dopamine and phenethylamine and means there are no dietary restrictions. It’s available in patch form. Learn about other medications used to treat depression.

What foods contain tyramine?

salami and other aged or cured meats. Other foods that contain high levels of tyramine are: aged cheeses, such as Brie, cheddar, Gouda, Parmesan, Swiss, and blue cheese. alcohol, especially chianti, vermouth, and beers. fava beans. raisins, dates, and other dried fruits. tofu.

What foods have high tyramine levels?

Foods with dangerously high levels of tyramine include: soy sauce and other fermented soy products. sauerkraut.

What Are Monoamine Oxidase Inhibitors?

Monoamine oxidase inhibitors (MAOIs) are an extremely strong class of antidepressants that treat depression by preventing the breakdown of the brain chemicals serotonin, dopamine, and norepinephrine . This helps them do their work of regulating your mood.

What are the side effects of MAOI?

Common side effects of MAOIs may include: Sleepiness, or trouble getting to sleep. Dizziness, lightheadedness, and fainting. Dry mouth, blurred vision, and appetite changes. High or low blood pressure. Changes in heart rate and rhythm.

What enzymes help remove neurotransmitters from the brain?

An enzyme called monoamine oxidase helps to remove them from your brain. MAOIs stop that enzyme from being able to work as it usually does, which leaves higher levels of neurotransmitters in your brain where they can work on cells that are affected by depression.

What is the best medication for bipolar depression?

MAOIs approved by the FDA to treat bipolar depression include: Isocarboxazid ( Marplan) Phenelzine ( Nardil) Selegiline ( Emsam) Tranylcypromine ( Parnate) Like other classes of antidepressants, MAOIs take several weeks to begin working.

Can MAOI cause high blood pressure?

Drug interactions. As with eating certain foods, taking certain medications can also cause dangerous and sudden high blood pressure when they are taken at the same time as MAOIs. This includes other antidepressants, pain medications, and cold and allergy medications. It’s important to tell your doctor or pharmacist about any medications you are taking, including herbal supplements, if you are prescribed an MAOI.

Can you take MAOI while pregnant?

This risk is highest when you’ve just started taking MAOIs or the doctor recently changed your dosage. The longer you’ve been taking an MAOI, the more likely you are to have these symptoms. If you are pregnant. There’s little information on the safety of MAOIs during pregnancy.

Can MAOI be stopped?

It’s important that you talk to your doctor before you decide to stop taking an MAOI. Stopping suddenly can cause withdrawal symptoms, which can be dangerous to your health, including:

Overview

Side effects

People taking MAOIs generally need to change their diets to limit or avoid foods and beverages containing tyramine, which is found in products such as cheese, soy sauce, and salami. If large amounts of tyramine are consumed, they may develop a hypertensive crisis, which can be fatal. Examples of foods and beverages with potentially high levels of tyramine include animal liver and fermented substances, such as alcoholic beverages and aged cheeses. Excessive concentration…

Medical uses

Mechanism of action

History

List of MAO inhibiting drugs

Overview

Mechanism of action

Interactions

Classification

Toxicity

Side effects

Medical uses

Treatment

Research

• Hydracarbazine: This is a compound with MAOI properties that is utilized primarily to lower blood pressure. There isnt much formal research that has been conducted utilizing just this compound. Isoniazid (Nydrazid): Isoniazid is significant and important to note because it lead researchers to investigate biological causes of major depression. This ...

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