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what are late effects of radiation

by Bert Walker PhD Published 3 years ago Updated 2 years ago
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Radiation to the brain can also have side effects that show up later – usually from 6 months to many years after treatment ends. These delayed effects can include serious problems such as memory loss, stroke-like symptoms, and poor brain function.Dec 10, 2020

When do late side effects from radiation therapy happen?

The side effects of radiation therapy depend on the area of the body that receives radiation. Early side effects happen shortly after you receive radiation therapy. Late side effects can happen months to years after you receive radiation therapy. Late side effects of radiation therapy may be permanent.

What are the bad and good effects of radiation?

Radiation treatment to the chest may cause side effects such as:

  • Sore throat
  • Swallowing problems
  • Loss of appetite
  • Cough
  • Shortness of breath

How long do late side effects from radiation therapy last?

What are the most common long-term side effects of radiation? "Generally, the side effects of radiotherapy are related only to the area of the body that was treated," says Dr. Nowlan. "The only long-term side effect of radiation that occurs outside the area that was treated is some lingering mild fatigue, which typically fades within three to six months."

How long does it take to recover from radiation treatment?

The general effects of radiation therapy like fatigue, nausea, and headaches resolve fairly quickly after treatment. Your body just needs time to process the radiation but can recover within a few weeks. Delayed side effects of radiation therapy, on the other hand, may require further treatment to alleviate.

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What are the long-term problems of radiation?

you might have permanent hair loss within the treated area. you might develop red spidery marks on your skin (telangiectasia) caused by small broken blood vessels. drainage channels to the arms or legs can become partly blocked resulting in swelling called lymphoedema.

Does radiation cause pain years later?

It tends to develop in the years following treatment and slowly worsens over time. Symptoms can include pain, loss of strength, decreased feeling (sensation), loss of coordination, or loss of movement or function of the muscle. The area affected will depend on the area that was in the radiation field.

What are late effects of cancer?

What cancer treatments cause late effects?TreatmentLate effectsChemotherapyDental problems Early menopause Hearing loss Heart problems Increased risk of other cancers Infertility Loss of taste Lung disease Nerve damage Osteoporosis Reduced lung capacity5 more rows

Does radiation ever leave your body?

The radiation stays in the body for anywhere from a few minutes to a few days. Most people receive internal radiation therapy for just a few minutes. Sometimes, internal radiation therapy can be given for more time. If so, they stay in a private room to limit other people's exposure to radiation.

When do radiation side effects peak?

The side effects of radiotherapy usually peak up to two weeks after treatment has finished. The effects of radiotherapy continue developing, and it may take a further couple of weeks to several months for you to feel normal, depending on the area of the body that has been treated.

How long does it take to recover from radiation?

Even though most radiation treatments only target specific collections of cancer cells, the effects of radiation can easily spread to nearby cells. Most recover within a few weeks, but some injuries develop later or require a longer recovery process.

What are the most common side effects of radiation therapy?

Common Side Effects from Radiation TherapyHair loss.Appetite changes.Mouth and throat changes.Trouble swallowing.Swelling.Coughing.Diarrhea.Nausea and vomiting.More items...

How long does radiation stay in your body after cancer treatment?

For most people, the cancer experience doesn't end on the last day of radiation therapy. Radiation therapy usually does not have an immediate effect, and it could take days, weeks or months to see any change in the cancer. The cancer cells may keep dying for weeks or months after the end of treatment.

What are the effects of radiation on the body?

Radiation induced inflammation leading to fibrosis, poor vascularity, and scarring

What are the side effects of radiation therapy for head and neck cancer?

Late side effects include: permanent loss of saliva; osteoradionecrosis; radiation recall myositis, pharyngoesophageal stenosis; dental caries; oral cavity necrosis; fibrosis; impaired wo und healing ; skin changes and skin cancer; lymphedema; hypothyroidism, hyperparathyroidism, lightheadedness, dizziness and headaches; secondary cancer; and eye, ear, neurological and neck structures damage. Patients who undergo radiotherapy for nasopharyngeal carcinoma tend to suffer from chronic sinusitis. These side effects present difficult challenges to the patients and their caregivers and require life-long strategies to alleviate their deleterious effect on basic life functions and on the quality of life. This review presents these side effects and their management.

What causes caries after RT?

Factors enhancing the occurrence of caries after RT include the increase in the number of oral caries producing bacteria (Streptococcus mutansand Lactobacillusspecies), reduced concentrations of salivary antimicrobial proteins, and loss of saliva’s mineralizing components [14].

What are the side effects of RT?

Late side effects include permanent loss of saliva; osteoradionecrosis; pharyngoesophageal stenosis; dental caries; oral cavity necrosis; fibrosis; radiation recall myositis, impaired wound healing; skin changes and skin cancer; lymphedema; hypothyroidism, hyperparathyroidism, lightheadedness, dizziness and headaches; secondary cancer; and eye, ear, neurological and neck structures damage. This manuscript reviews the major late side effects of RT and their management (Table 1).

Does radiation damage thyroid glands?

Radiation induced damage to the thyroid gland

What is a late effect?

A late effect is as a side effect related to a cancer diagnosis or treatment that happens months to years after treatment. Some side effects that you develop during treatment can last for months to years after treatment is completed (for example, fatigue or neuropathy). These are often called long term side effects.

What are the effects of radiation on the head and neck?

Late Effects After Radiation for Head and Neck Cancer. Side effects from radiation treatment are directly related to the area of the body being treated. Any area in the treatment field has a risk of being damaged, causing side effects. As radiation techniques have improved over the years, the risk of late effects has decreased.

What happens if you have radiation in your ears?

Hearing and Ear Changes. Radiation to the head can damage the cochlea (a part of the inner ear), and/or the ear canal. This can lead to hearing loss, dryness of the ear canal and fluid collection in the inner ear. These problems could result in: A full or clogged ear feeling. Dizziness.

What happens when you have a scar on your skin?

The soft tissue and muscles under the skin can develop scarring and/or shrinkage, which can lead to a loss of flexibility and movement or chronic swelling in this area .

Can radiation damage the salivary glands?

Radiation to the head and neck can damage the salivary (parotid) glands. This can lead to:

Can you smoke while on radiation?

You should avoid smoking, secondhand smoke, vaping, hookah, and using oral tobacco products, which can make long-term and late effects from radiation worse. Because the head & neck treatment field can encompass several other structures and organs, the risks to these areas are discussed below.

Can radiation cause fractures?

Radiation can cause small cracks (fractures) in the bones that are in the treatment field. Try to avoid trauma including falls or accidents. If you do get hurt, ask your provider if you need any imaging tests to check for bone damage.

How to manage radiation side effects?

Chronic diarrhea or poor absorption of food is one of the common late side effects of radiation. It can usually be managed with diet changes that include going to foods that don't induce diarrhea, including low fiber, low fat, and high protein foods. And an example would be reducing the amount of salads the patient eats. Daily psyllium is used with only half the prescribed amount of water to help bulk stools in certain cases. And over-the-counter loperamide either is needed or prophylactically. For example, one tablet daily or twice daily can be used to help produce the amount of bowel movements per day.

How long does it take for radiation to go away?

In summary, acute reactions from radiation therapy can usually be managed conservatively and will resolve in two to three weeks after treatment. The late side effects of radiation therapy are not common, but they do occur in a small percentage of patients. However, there are effective treatments for most of these late side effects. And remember, recurrent cancer or a second primary can mimic the less common side effects of radiation therapy, so should be given more attention. Thank you. That's the end of my talk for today. I appreciate your attention, and if you have any feedback, that would be appreciated.

What is radiation proctitis?

Radiation proctitis, which includes bowel urgency, bleeding, and --- and/or incontinence, is caused by radiation damage to the distal rectum, the anal canal, and sphincter muscles and nerves. Now, there are some uncommon late effects of radiation therapy.

What is the best treatment for radiation induced proctitis?

For radiation-induced proctitis, barrier creams are used, such as hydrocortisone cream ointment or suppositories, or pra --- pramoxine. For skin reactions, emollients are used, as recommended by the radiation oncologist and as needed throughout treatments. Now, the late side effects of radiation therapy: Ten percent or less ...

Why is sterility caused by radiation?

The infertility and sterility is caused by the destruction of immature oocytes in females . Radiation therapy affects any rapidly dividing cells. So, cells that produce sperm are quite sensitive to radiation damage. The vaginal stenosis and dryness is caused by scarring and fibrosis from radiation therapy and loss of hormones from non-functioning ovaries, as mentioned earlier.

How long does radiation therapy last?

Most people suffer some acute side effects. They are self-limiting and usually resolve two to three weeks after treatments. They will occur with both external beam and brachytherapy treatments. And there is no way to determine who will or will not suffer ...

What organs are at risk for pelvic radiation?

The organs at risk when treated with pelvic radiation therapy are the colon, small bowel, the bladder, ureters, urethra, the genital organs and spinal cord, skin, soft tissue, muscles, bones, vasculature, nerves in the radiation field, and the lymph --- lymphatic system. Now, there're two types of effects of radiation therapy, ...

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1.Late (Delayed) Effects of …

Url:https://www.nrc.gov/docs/ML1122/ML11229A694.pdf

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Url:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533405/

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