
...
Other SSRIs include :
- escitalopram (Lexapro)
- citalopram (Celexa)
- fluvoxamine (Luvox, Luvox CR)
- fluoxetine (Prozac, Sarafem, Symbyax)
- paroxetine (Paxil, Paxil CR, Pexeva)
- vilazodone (Viibryd)
Precautions
What does sertraline mean? Sertraline is an antidepressant in a group of drugs called selective serotonin reuptake inhibitors (SSRIs). Sertraline affects chemicals in the brain that may be unbalanced in people with depression, panic, anxiety, or obsessive-compulsive symptoms.
What does the name sertraline mean?
Well no! - (as a simple google search can confirm) - Zoloft is Sertraline and Paxil is Paroxetine Both are SSRI’s (Serotonin Specific Re-uptake Inhibitors) which just mean they both interfere with the way naturally occurring Serotonin is reabsorbed by the body - this has the effect of increasing the overall availability of this hormone.
Is sertraline the same thing as Zoloft?
Sertraline oral tablet is a prescription drug that’s available as the brand-name drug Zoloft.It’s also available as a generic drug. Generic drugs usually cost less.
Is sertraline a brand name?
Sertraline is a safe and effective treatment for depression, and it holds a far lesser potential for drowsiness than other antidepressants. It is prescribed for major depressive disorder, panic disorder, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), premenstrual dysphoric disorder, postpartum depression, and social ...
Is sertraline a strong antidepressant?
See more
What is the generic name for sertraline?
They're both brand-name drugs. The generic version of Prozac is fluoxetine, while the generic version of Zoloft is sertraline hydrochloride. Both drugs are selective serotonin reuptake inhibitors (SSRIs).
What does sertraline do to the body?
Sertraline works by increasing the levels of a mood-enhancing chemical called serotonin in your brain. It helps many people recover from depression, and has fewer unwanted side effects than older antidepressants. Sertraline comes as tablets, which are available only on prescription.
What is equivalent to sertraline?
Lexapro, Prozac, Effexor, Cymbalta, and Wellbutrin are some Zoloft alternatives. Get the full list here. Individuals with depression or anxiety may be prescribed a medication called Zoloft (sertraline).
What is 50mg of sertraline used for?
Sertraline is one of a group of medicines called Selective Serotonin Re-uptake Inhibitors (SSRIs); these medicines are used to treat depression and/or anxiety disorders. Sertraline can be used to treat: Depression and prevention of recurrence of depression (in adults).
How long can you stay on sertraline?
For depression it might be six months, for OCD it might be 12 months and for other anxiety related conditions such as PTSD and panic disorder it might be up to 18 months. If you stop taking the sertraline too soon, there is more chance that your symptoms will come back.
What should you avoid when taking sertraline?
Generally, individuals taking sertraline will need to avoid nonsteroidal anti-inflammatory drugs (NSAIDs) like naproxen, aspirin, ibuprofen; blood thinners; and other medications that increase serotonin levels. Too much serotonin can cause serotonin syndrome.
Does sertraline cause weight gain?
For some people who take an SSRI such as Prozac (fluoxetine) or Zoloft (sertraline), one of these possible side effects is weight gain. Research suggests that the amount of weight typically gained while on an SSRI is modest.
What are the top 3 antidepressants?
The most effective antidepressants for adults revealed in major...escitalopram.paroxetine.sertraline.agomelatine.mirtazapine.
What is the safest antidepressant?
Among the newer antidepressants, bupropion and venlafaxine were associated with the highest case fatality rates. In addition, among SSRIs, citalopram and fluvoxamine appeared to be related to higher mortality rates in overdose, whereas fluoxetine and sertraline were the safest [188].
What is the most common side effect of sertraline?
Commonly reported side effects of sertraline include: diarrhea, dizziness, drowsiness, dyspepsia, fatigue, insomnia, loose stools, nausea, tremor, headache, paresthesia, anorexia, decreased libido, delayed ejaculation, diaphoresis, ejaculation failure, and xerostomia.
Does sertraline 50 mg make you gain weight?
Antipsychotic drugs, antidepressants , and mood stabilizers are common drugs that have the most potential to increase weight gain. All 12 of the leading antidepressants, including fluoxetine (Prozac), sertraline (Zoloft), and escitalopram (Lexapro), make gaining weight more likely.
Why should I take sertraline at night?
Your doctor will most likely recommend a once-a-day dosage of sertraline (Zoloft). You can take it either in the morning or evening, depending on your lifestyle and any side effects you experience. For example, if sertraline makes you drowsy, taking it at night might be your best choice.
What is the most common side effect of sertraline?
Commonly reported side effects of sertraline include: diarrhea, dizziness, drowsiness, dyspepsia, fatigue, insomnia, loose stools, nausea, tremor, headache, paresthesia, anorexia, decreased libido, delayed ejaculation, diaphoresis, ejaculation failure, and xerostomia.
Are there any long term side effects of sertraline?
Two recent reviews of research in this area concluded that discontinuation effects, sexual dysfunction, weight gain, and sleep disturbance (multiple long-wake periods) are adverse effects of long-term SSRI use.
How long do sertraline take to start working?
by Drugs.com Zoloft (sertraline), a common selective serotonin reuptake inhibitor (SSRI) antidepressant, can take about 4 to 6 weeks of regular dosing to reach its full therapeutic effect for depression. The initial effects may begin within the first 1 to 2 weeks of treatment.
Does your brain go back to normal after antidepressants?
"The fact that antidepressant withdrawal can be so prolonged suggests that the drug has changed the brain and that those changes are taking a very long time to return to normal and it may be the case that sometimes they don't go back to normal."
Before Taking This Medicine
You should not use sertraline if you are allergic to it, or if you also take pimozide. Do not use the liquid form of sertraline if you are taking d...
How Should I Take Sertraline?
Take sertraline exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your do...
What Happens If I Miss A Dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to...
What Should I Avoid While Taking Sertraline?
Do not drink alcohol.See also: Sertraline and alcohol (in more detail)Ask your doctor before taking a nonsteroidal anti-inflammatory drug (NSAID) f...
sertraline Dosing Information
Usual Adult Dose of Sertraline for Depression:Initial dose: 50 mg orally once a dayMaintenance Dose: 50 to 200 mg orally once a dayComments:-Dose a...
What Other Drugs Will Affect Sertraline?
Taking sertraline with other drugs that make you sleepy can worsen this effect. Ask your doctor before taking a sleeping pill, narcotic medication,...
What is sertraline?
Sertraline is an antidepressant that belongs to a group of drugs called selective serotonin reuptake inhibitors (SSRIs). Sertraline affects chemicals in the brain that may be unbalanced in people with depression, panic, anxiety, or obsessive-compulsive symptoms.
What other drugs will affect sertraline?
Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV.
What are the symptoms of serotonin syndrome?
Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.
What happens if you are allergic to sertraline?
Get emergency medical help if you have signs of an allergic reaction to sertraline: skin rash or hives (with or without fever or joint pain); difficulty breathing; swelling of your face, lips, tongue, or throat.
Can you take sertraline with pimozide?
You should not use sertraline if you also take pimozide, or if you are being treated with methylene blue injection.
Can you share Sertraline with children?
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use sertraline only for the indication prescribed.
Can sertraline cause false results?
Sertraline may cause false results on a drug-screening urine test . Tell the laboratory staff that you use this medicine.
When was sertraline first used?
Sertraline was invented and developed by scientists at Pfizer and approved for medical use in the United States in 1991. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication. In 2016, sertraline was the most commonly prescribed psychiatric medication in the United States and in 2019, it was the twelfth most commonly prescribed medication in the United States, with over 37 million prescriptions.
How much weight did Sertraline cause?
Over more than six months of sertraline therapy for depression, people showed a nonsignificant weight increase of 0.1%. Similarly, a 30-month-long treatment with sertraline for OCD resulted in a mean weight gain of 1.5% (1 kg). Although the difference did not reach statistical significance, the average weight gain was lower for fluoxetine (1%) but higher for citalopram, fluvoxamine and paroxetine (2.5%). Of the sertraline group, 4.5% gained a large amount of weight (defined as more than 7% gain). This result compares favorably with placebo, where, according to the literature, 3–6% of patients gained more than 7% of their initial weight. The large weight gain was observed only among female members of the sertraline group; the significance of this finding is unclear because of the small size of the group.
How long does sertraline stay in your system?
In the blood, it is 98.5% bound to plasma proteins. Its half-life in the body is 13–45 hours and, on average, is about 1.5 times longer in women (32 hours) than in men (22 hours), leading to a 1.5-times-higher exposure in women. According to in vitro studies, sertraline is metabolized by multiple cytochrome 450 isoforms; however, it appears that in the human body CYP2C19 plays the most important role, followed by CYP2B6. Poor CYP2C19 metabolizers have 2.7-fold higher levels of sertraline, and intermediate metabolizers - 1.4-fold higher levels, than normal (extensive) metabolizers. In contrast, poor CYP2B6 metabolizers have 1.6-fold higher levels of sertraline and intermediate metabolizers - 1.2-fold higher levels.
How long does it take for sertraline to go away?
It typically occurs within a few days from drug discontinuation and lasts a few weeks. The withdrawal symptoms for sertraline are less severe and frequent than for paroxetine, and more frequent than for fluoxetine. In most cases symptoms are mild, short-lived, and resolve without treatment.
How effective is sertraline for OCD?
Sertraline is effective for the treatment of O CD in adults and children. It was better tolerated and, based on intention-to-treat analysis, performed better than the gold standard of OCD treatment clomipramine. Continuing sertraline treatment helps prevent relapses of OCD with long-term data supporting its use for up to 24 months. It is generally accepted that the sertraline dosages necessary for the effective treatment of OCD are higher than the usual dosage for depression. The onset of action is also slower for OCD than for depression. The treatment recommendation is to start treatment with a half of maximal recommended dose for at least two months. After that, the dose can be raised to the maximal recommended in the cases of unsatisfactory response.
When did Zoloft expire?
The US patent for Zoloft expired in 2006, and sertraline is available in generic form and is marketed under many brand names worldwide.
Is sertraline the same as escitalopram?
In general, sertraline efficacy is similar to that of other antidepressants. For example, a meta-analysis of 12 new-generation antidepressants showed that sertraline and escitalopram are the best in terms of efficacy and acceptability in the acute-phase treatment of adults with depression. Comparative clinical trials demonstrated that sertraline is similar in efficacy against depression to moclobemide, nefazodone, escitalopram, bupropion, citalopram, fluvoxamine, paroxetine, venlafaxine and mirtazapine. Sertraline may be more efficacious for the treatment of depression in the acute phase (first 4 weeks) than fluoxetine.
What is citalopram used for?
more. Citalopram may be used to treat depression and off-label to treat other conditions such as anxiety and OCD . Side effects such as insomnia, drowsiness, dry mouth, nausea, and increased sweating may... View.
What is the half life of a drug?
The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.
Is Sertraline a good antidepressant?
Sertraline is an effective antidepressant with less potential for drowsiness than other antidepressants. Prescribed for Obsessive Compulsive Disorder, Major Depressive Disorder, Panic Disorder... Celexa is an effective antidepressant but it may cause more side effects than other SSRIs, such as escitalopram.
How to see the price of Sertraline?
To view the price of the drug, click on the brand name . The generic Sertraline is manufactured by one company. Medindia's drug directory has currently 115 Brands of Sertraline listed. New generics and brands are constantly being updated as and when they are approved by drug controller and available in the pharmacies.
What is PTSD treatment?
Post Traumatic Stress Disorder (PTSD), is a mental condition triggered by a traumatic event. PTSD treatment includes pyschotherapy , behavior therapy and medications. Vulvodynia. Vulvodynia is chronic pain near the vaginal opening that can affect women of any age group. Burning Mouth Syndrome.
Is Spinocerebellar Ataxia a genetic disease?
Spinocerebellar ataxia (SCA) is a progressive, neurodegenerative, genetic disease, which has no cure and treated only symptomatically.
What are some alternatives to sertraline?
Natural alternatives to sertraline include targeted supplements therapy, St. John’s wort and herbal remedies, and alternative medicines such as valerian, kava, and vitamin B6 for the treatment of depression and anxiety in certain patients .
What can I take instead of sertraline?
There are a number of alternative selective serotonin reuptake inhibitors (SSRIs), such as:
What is the best antidepressant with the least side effects?
Recent research shows that seven antidepressants are more effective than other antidepressants are. These seven antidepressants include:
What antidepressants can I take?
Consumers can take other antidepressants in different drug classes, such as: Bupropion (Wellbutrin), an aminoketone. Duloxetine (Cymbalta), a serotonin-norepinephrine reuptake inhibitor (SNRI) Venlafaxine (Effexor XR), another SNRI.
Is escitalopram better than sertraline?
Research suggests Lexapro® is more effective and better tolerated than sertraline, but another study shows sertraline led to outcomes that were as good or better than Lexapro®.
Does fluoxetine help with depression?
In one study, both fluoxetine and sertraline improved depression, but sertraline was associated with fewer side effects so more patients remained on the medication longer. In another study, the two medications showed similar effectiveness in patients with depression and anxiety.
Does sertraline cause weight gain?
Many antidepressants, such as sertraline, are associated with weight gain . Bupropion, sold under the brand name Wellbutrin, is the only antidepressant that leads to long-term weight loss.
What is the half life of a drug?
The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.
Can bupropion cause seizures?
Using buPROPion with alcohol may increase the risk of uncommon side effects such as seizures...
Is Zoloft an antidepressant?
Zoloft is an effective antidepressant with less potential for drowsiness than many other antidepressants. Prescribed for Obsessive Compulsive Disorder, Major Depressive Disorder, Panic Disorder... Cymbalta has antidepressant, anti-anxiety, and pain-relieving properties; however, it has been associated with a discontinuation syndrome on withdrawal ...

Overview
Sertraline is used to treat depression, panic attacks, obsessive compulsive disorder, post-traumatic stress disorder, social anxiety disorder (social phobia), and a severe form of premenstrual syndrome (premenstrual dysphoric disorder).
May Treat: Major depressive disorder · Panic disorder · Premenstrual dysphoric disorder · Obsessive-compulsive disorder · Post traumatic stress disorder and more
Brand Names: Zoloft
Drug Class: Antidepressant - Selective Serotonin Reuptake Inhibitors (SSRIs)
Availability: Prescription Required
Pregnancy: Consult a doctor before using
May Treat: Major depressive disorder · Panic disorder · Premenstrual dysphoric disorder · Obsessive-compulsive disorder · Post traumatic stress disorder and more
Brand Names: Zoloft
Drug Class: Antidepressant - Selective Serotonin Reuptake Inhibitors (SSRIs)
Availability: Prescription Required
Pregnancy: Consult a doctor before using
Lactation: Consult a doctor before using
Alcohol: Limit intake while taking this medication
Driving: May cause drowsiness or dizziness. Use caution
Society and culture
Medical uses
Contraindications
Side effects
Overdose
The US patent for Zoloft expired in 2006, and sertraline is available in generic form and is marketed under many brand names worldwide.
In May 2020, the FDA placed Zoloft on the list of drugs currently facing a shortage.
Interactions
Sertraline has been approved for major depressive disorder (MDD), obsessive–compulsive disorder (OCD), posttraumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), panic disorder, and social anxiety disorder (SAD). Sertraline is not approved for use in children except for those with OCD.
Multiple controlled clinical trials established efficacy of sertraline for the treatment of depression. …
Pharmacology
Sertraline is contraindicated in individuals taking monoamine oxidase inhibitors or the antipsychotic pimozide. Sertraline concentrate contains alcohol and is therefore contraindicated with disulfiram. The prescribing information recommends that treatment of the elderly and patients with liver impairment "must be approached with caution". Due to the slower elimination of sertraline in these groups, their exposure to sertraline may be as high as three times the average exposure for the …