what are side effects of thiamine

Call your doctor at once if you have a serious side effect such as:

• blue colored lips;
• chest pain, feeling short of breath;
• black, bloody, or tarry stools; or
• coughing up blood or vomit that looks like coffee grounds.

Full Answer

What are the side effects of too much thiamine?

Side effects requiring immediate medical attention

• Coughing
• difficulty in swallowing
• hives
• itching of skin
• swelling of face, lips, or eyelids
• wheezing or difficulty in breathing

What happens if you have too much thiamin?

You can get recommended amounts of thiamin by eating a variety of foods, including the following:

• Whole grains and fortified bread, cereal, pasta, and rice
• Meat (especially pork) and fish
• Legumes (such as black beans and soybeans ), seeds, and nuts

Is thiamine bad for You?

Thiamine is generally a very safe medicine. Taking too much is unlikely to harm you or your child. If you're worried, speak to a pharmacist or doctor. 5. Side effects Like all medicines, thiamine can cause side effects in some people. But most people have no side effects or only minor ones. Common side effects

What does thiamine do to your body?

Thiamine or vitamin B1 is a crucial nutrient for taking energy from food and for turning it into energy for the brain, heart and the nerves. Thiamine is required to make ATP or Adenosine triphosphate, which is the main energy-carrying molecule of the body.

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Are there side effects to taking thiamine?

Side effects of thiamine include: warmth. severe allergic reaction (anaphylaxis) skin discoloration.

Who should not take thiamine?

You should not use thiamine if you have ever had an allergic reaction to it. Ask a doctor or pharmacist if it is safe for you to take this medicine if: you have any other medical conditions; you take other medications or herbal products; or.

What are the symptoms of too much thiamine?

Symptoms include: Awakening at night short of breath. Increased heart rate. Shortness of breath with activity.

What does thiamine do to your body?

Overview. Thiamin (vitamin B-1) helps the body generate energy from nutrients. Also known as thiamine, thiamin is necessary for the growth, development and function of cells. Most people get enough thiamin from the food they eat.

Why would a doctor prescribe thiamine?

Thiamine is used to treat or prevent vitamin B1 deficiency. Thiamine injection is used to treat beriberi, a serious condition caused by prolonged lack of vitamin B1. Thiamine taken by mouth (oral) is available without a prescription. Injectable thiamine must be given by a healthcare professional.

Does thiamine raise blood pressure?

also showed that thiamine has beneficial effects on the blood pressure of individuals with hyperglycemia, as it lowers diastolic blood pressure and mean arterial pressure.

Can too much thiamine be harmful?

Thiamine is generally a very safe medicine. Taking too much is unlikely to harm you or your child.

Is it safe to take thiamine supplement?

Thiamine is generally safe. Very high doses may cause stomach upset. Taking any one of the B vitamins for a long period of time can result in an imbalance of other important B vitamins. For this reason, you may want to take a B-complex vitamin, which includes all the B vitamins.

Does thiamine make you sleepy?

Being deficient in thiamine can show up as fatigue (tiredness), which may come on quickly or over time, depending on the severity of the deficiency. Some sources suggest fatigue can occur within just a few weeks of deficiency ( 2 ). This symptom makes sense, given the role of thiamine in converting food into energy.

When is the best time to take thiamine?

Thiamine tablets are usually taken once a day. Doses of 25-100 mg are sufficient to prevent mild deficiency. You can take the tablets at whatever time of day you find easiest to remember, either before or after meals.

Is thiamine good for the liver?

This discovery of the potent anti-steatotic effect of thiamine may prove clinically useful in managing fatty liver-related disorders.

Does thiamine give you energy?

Also known as thiamine, B1 helps your body turn food into energy.

What to know before taking thiamine?

Before you receive injectable thiamine, tell your doctor if you have kidney disease.

What is thiamine?

Thiamine is vitamin B1. Thiamine is found in foods such as cereals, whole grains, meat, nuts, beans, and peas. Thiamine is important in the breakdown of carbohydrates from foods into products needed by the body.

How should I take thiamine?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

What should I avoid while taking thiamine?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Can you take thiamine if you are allergic to it?

You should not use thiamine if you have ever had an allergic reaction to it. Ask a doctor or pharmacist before taking thiamine if you have any medical conditions, if you take other medications or herbal products, or if you are allergic to any drugs or foods.

Can you take thiamine without a prescription?

Thiamine injection is used to treat beriberi, a serious condition caused by prolonged lack of vitamin B1. Thiamine taken by mouth (oral) is available without a prescription. Injectable thiamine must be given by a healthcare professional. Thiamine may also be used for purposes not listed in this medication guide.

Does thiamine increase with age?

The recommended dietary allowance of thiamine increases with age . Follow your healthcare provider's instructions. You may also consult the National Academy of Sciences "Dietary Reference Intake" or the U.S. Department of Agriculture's "Dietary Reference Intake" (formerly "Recommended Daily Allowances" or RDA) listings for more information.

How long does it take for thiamine to work?

People taking thiamine showed more improvements after 6 weeks. But after 12 weeks, symptoms were the same for those taking thiamine or placebo. Dementia. Taking thiamine is linked to a reduced risk of dementia in people with alcohol use disorder.

What is thiamine in food?

Thiamine is a vitamin, also called vitamin B 1. Vitamin B1 is found in many foods including yeast, cereal grains, beans, nuts, and meat. It is often used in combination with other B vitamins, and found in many vitamin B complex products. Vitamin B complexes generally include vitamin B1 (thiamine), vitamin B 2 (riboflavin), vitamin B3 ( niacin / niacinamide ), vitamin B5 (pantothenic acid), vitamin B6 (pyridoxine), vitamin B12 ( cyanocobalamin ), and folic acid. However, some products do not contain all of these ingredients and some may include others, such as biotin, para- aminobenzoic acid (PABA), choline bitartrate, and inositol.

Why do we take thiamine by mouth?

Taking thiamine by mouth helps prevent and treat thiamine deficiency. A brain disorder caused by low levels of thiamine (Wernicke-Korsakoff syndrome). Thiamine helps decrease the risk and symptoms of a specific brain disorder called Wernicke-Korsakoff syndrome (WKS). This brain disorder is related to low levels of thiamine.

Does thiamine help with heart failure?

Some research shows that taking extra thiamine might slightly improve the function of the heart. But thiamine doesn't seem to help people who suddenly develop heart failure and don' t have thiamine deficiency.

Does thiamine help with menstrual pain?

Taking thiamine seems to reduce menstrual pain in teenage girls and young women. Possibly Ineffective for. Surgery to improve blood flow to the heart (CABG surgery). Some research shows that giving thiamine into the vein before and after CABG surgery does not lead to better outcomes than placebo.

Does thiamine cause cataracts?

High thiamine intake as part of the diet is associated with reduced odds of developing cataracts. Kidney damage in people with diabetes ( diabetic nephropathy ). Early research shows that taking high-dose thiamine (300 mg daily) decreases the amount of albumin in the urine in people with type 2 diabetes.

Is thiamine safe to take by mouth?

Side Effects. When taken by mouth: Thiamine is LIKELY SAFE when taken by mouth in appropriate amounts, although rare allergic reactions and skin irritation have occurred. When given by IV: Thiamine is LIKELY SAFE when given appropriately by a healthcare provider.

Who determines the need for thiamine?

Increased need for thiamine should be determined by your health care professional.

Can older adults take thiamine?

Studies have shown that older adults may have lower blood levels of thiamine than younger adults. Your health care professional may recommend that you take a vitamin supplement that contains thiamine.

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Sorry, we have no data available. Please contact your doctor or pharmacist.

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Sorry, we have no data available. Please contact your doctor or pharmacist.

If experienced, these tend to have a Severe expression i

Sorry, we have no data available. Please contact your doctor or pharmacist.

If experienced, these tend to have a Less Severe expression i

Sorry, we have no data available. Please contact your doctor or pharmacist.

Are you currently using thiamine HCl vial?

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Why do people take thiamine?

Some people use thiamine for maintaining a positive mental attitude; enhancing learning abilities; increasing energy; fighting stress; and preventing memory loss, including Alzheimer's disease .

What Other Drugs Interact with Thiamine?

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider, or pharmacist first.

What is thiamine in food?

Thiamine is a prescription and over-the-counter ( OTC) vitamin, also called vitamin B1. Vitamin B1 is found in many foods including yeast, cereal grains, beans, nuts, and meat. It is often used in combination with other B vitamins.

Can you take vitamin B1 if you are allergic to thiamine?

This medication contains thiamine. Do not take vitamin B1 if you are allergic to thiamine or any ingredients contained in this drug.

Can pregnant women take thiamine?

Controlled studies in pregnant women show no evidence of fetal risk. Only use thiamine in doses exceeding the recommended daily average during pregnancy with caution if benefits outweigh risks. Animal studies show risk and human studies are not available, or neither animal nor human studies were done.

Does thiamine have any interactions with other drugs?

Thiamine has no known severe interactions with other drugs. Thiamine has no known serious interactions with other drugs. Thiamine has mild interactions with at least 69 different drugs. This information does not contain all possible interactions or adverse effects.

How do you know if you have a thiamine deficiency?

1. Loss of Appetite. Share on Pinterest. One common early symptom of thiamine deficiency is a loss of appetite, or anorexia.

How long does it take for thiamine to cause irritable mood?

An irritable mood is noted to be one of the first symptoms of thiamine deficiency. It may occur within days or weeks of deficiency ( 9 ).

What is the role of thiamine in satiety?

Scientists believe that thiamine plays an important role in the regulation of satiety. It helps control the “satiety center” located in the hypothalamus of the brain.

Can thiamine deficiency affect motor nerves?

Thiamine deficiency can affect the motor nerves.

What foods are thiamines made of?

Since the human body is unable to produce thiamine, it must be consumed through various thiamine-rich foods, such as meat, nuts and whole grains.

Is fatigue a sign of thiamine deficiency?

Since fatigue is such a vague symptom with numerous possible causes, it can be commonly overlooked as a sign of thiamine deficiency. However, considering the vital role thiamine plays in converting food into fuel, it’s no surprise that fatigue and lack of energy is a common symptom of deficiency. ).

Can thiamine cause paresthesia?

The peripheral nerves that reach your arms and legs rely heavily on the action of thiamine. In cases of deficiency, peripheral nerve damage and paresthesia can occur. In fact, patients have experienced paresthesia in the beginning phases of thiamine deficiency ( 14. Trusted Source. , 15.

How long does thiamine stay in your body?

Some of it is stored in the liver for up to 18 days. Your body's ability to store it is limited, so make sure you eat foods rich in this nutrient regularly. Some foods, such as grains and breakfast cereals, are fortified with thiamine mononitrate. This water-soluble vitamin supports energy production. Your body's ability to store it is limited, so ...

What is the role of thiamine mononitrate?

The Role of Thiamine Mononitrate. Over time, thiamine deficiency can lead to more serious disorders, such as Wernicke-Korsakoff syndrome and beriberi. The latter, for instance, causes pain, tingling, mental confusion, loss of muscle function, shortness of breath and other symptoms.cause:

Can you take too much thiamine?

If you consume too much thiamine, the excess will be eliminated in urine. Therefore, whether you're getting vitamin B-1 from food or supplements, it's unlikely to cause any side effects unless you take extremely high doses.

How to measure thiamin levels?

Thiamin status is often measured indirectly by assaying the activity of the transketolase enzyme , which depends on TDP, in erythrocyte hemolysates in the presence and absence of added TDP [3]. The result, known as the "TDP effect," reflects the extent of unsaturation of transketolase with TDP. The result is typically 0%–15% in healthy people, 15%–25% in those with marginal deficiency, and higher than 25% in people with deficiency. Another commonly used measure of thiamin status is urinary thiamin excretion, which provides data on dietary intakes but not tissue stores [5]. For adults, excretion of less than 100 mcg/day thiamin in urine suggests insufficient thiamin intake, and less than 40 mcg/day indicates an extremely low intake [6].

How much thiamin is in the human body?

About 80% of the approximately 25–30 mg of thiamin in the adult human body is in the form of thiamin diphosphate (TDP; also known as thiamin pyrophosphate), the main metabolically active form of thiamin.

Why does thiamin dissolve in water?

Because thiamin dissolves in water, a significant amount of the vitamin is lost when cooking water is thrown out [ 3 ]. Processing also alters thiamin levels in foods; for example, unless white rice is enriched with thiamin, it has one tenth the amount of thiamin in unenriched brown rice [ 10 ].

What is the most common source of thiamin?

Food sources of thiamin include whole grains, meat, and fish [ 2 ]. Breads, cereals, and infant formulas in the United States and many other countries are fortified with thiamin [ 2 ].The most common sources of thiamin in the U.S. diet are cereals and bread [ 8 ]. Pork is another major source of the vitamin.

What is a DRI for thiamin?

DRI is the general term for a set of reference values used for planning and assessing nutrient intakes of healthy people . These values, which vary by age and sex, include:

Where is thiamin absorbed?

Ingested thiamin from food and dietary supplements is absorbed by the small intestine through active transport at nutritional doses and by passive diffusion at pharmacologic doses [1]. Most dietary thiamin is in phosphorylated forms, and intestinal phosphatases hydrolyze them to free thiamin before the vitamin is absorbed [1]. The remaining dietary thiamin is in free (absorbable) form [1,2]. Humans store thiamin primarily in the liver, but in very small amounts [3]. The vitamin has a short half-life, so people require a continuous supply of it from the diet.

Is thiamine a water soluble vitamin?

Thiamin (or thiamine) is one of the water-solu ble B vitamins. It is also known as vitamin B1. Thiamin is naturally present in some foods, added to some food products, and available as a dietary supplement. This vitamin plays a critical role in energy metabolism and, therefore, in the growth, development, and function of cells [ 1 ].