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what are the long term side effects of protonix

by Wilfrid Wintheiser Sr. Published 3 years ago Updated 2 years ago
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COMMON side effects. If experienced, these tend to have a Less Severe expression. Diarrhea. Dizzy. Gas. Head Pain. Joint Pain. Stomach Cramps.

Taking pantoprazole long-term may cause you to develop stomach growths called fundic gland polyps. Talk with your doctor about this risk.
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Common side effects may include:
  • headache, dizziness;
  • stomach pain, gas, nausea, vomiting, diarrhea;
  • joint pain; or.
  • fever, rash, or cold symptoms (most common in children).

Full Answer

How long should I wait to eat after taking Protonix?

The Protonix helps my stomach pain and I'm OK if I eat 30 minutes or so after taking it. But a couple of times I didn't eat for several hours and got the worst gas and bloating!

Is Protonix a safe medication?

Protonix may not be suitable for some people including those with severe liver disease, osteoporosis or low bone mineral density, or low levels of magnesium in their blood. May increase the risk of osteoporosis-related fracture of the hip, wrist, or spine. Not suitable for children under five.

Does Protonix cause weight gain?

Weight gain is found among people who take Protonix, especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years. The phase IV clinical study analyzes which people take Protonix and have Weight gain.

What are the side effects of taking Flexeril long term?

The common side effects of Flexeril are:

  • Blurry vision
  • Mouth or throat dryness
  • Constipation
  • Dizziness
  • Constantly feeling tired
  • Stomach pain
  • Nausea
  • Muscle weakness
  • Gas
  • Diarrhea

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Is it safe to take Protonix long-term?

Do not take pantoprazole for more than 4 weeks without speaking to your doctor first. If your symptoms have not improved, you may need some tests to find out what's causing them.

What are the dangers of Protonix?

The most common side effects of PROTONIX in adults include: headache, diarrhea, nausea, stomach-area (abdominal) pain, vomiting, gas, dizziness, and joint pain.

Why you shouldn't take Protonix long-term?

Recent studies, however, have cited dangers thought to be associated with the long-term use of PPIs. Among them: an increased risk of kidney disease, osteoporosis, low magnesium or vitamin B12 in the blood, pneumonia, stroke, and contracting the Clostridium difficile (C. diff) bacterium.

What happens if you take pantoprazole for too long?

Fundic gland polyps warning: Long-term use (especially over 1 year) of pantoprazole can cause fundic gland polyps. These polyps are growths on the lining of your stomach that can become cancerous. To help prevent these polyps, you should use this drug for as short a time as possible.

What is a good substitute for Protonix?

Protonix.Dexilant.Prilosec.Famotidine.Prevacid.Esomeprazole.

Can you stop Protonix cold turkey?

Folks taking PPIs for treatment of stomach or duodenal ulcers for four to eight weeks do not require tapering down, and you can attempt to just stop them. Don't forget that relapse symptoms may occur.

How long can you stay on pantoprazole?

Adults—40 milligrams (mg) once a day for up to 8 weeks. Your doctor may want you to take pantoprazole for more than 8 weeks for certain conditions. Children 5 years of age and older weighing 40 kilograms (kg) or more—40 mg once a day for up to 8 weeks.

What is the safest antacid to take long term?

Proton pump inhibitors are accepted as the most effective initial and maintenance treatment for GERD. Oral pantoprazole is a safe, well tolerated and effective initial and maintenance treatment for patients with nonerosive GERD or erosive esophagitis.

How long can you take Protonix?

PROTONIX is used in adults: for up to 8 weeks to heal acid-related damage to the lining of the esophagus (erosive esophagitis or EE) and to relieve symptoms caused by gastroesophageal reflux disease (GERD). If needed, your doctor may decide to prescribe another 8 weeks of PROTONIX.

Why does pantoprazole cause weight gain?

You may gain weight as you start eating like usual again. The weight gain may not be caused by pantoprazole itself. Instead, it could be a sign that your appetite is returning as your condition is treated. If you're concerned about gaining weight while you're taking pantoprazole, talk with your doctor.

How do I wean off Protonix?

Slowly taper off the PPI over 2-4 weeks (the higher the dose, the longer the taper). While the taper is being completed, use the following for bridge therapy to reduce the symptoms of rebound hyperacidity. Encourage regular aerobic exercise. Encourage a relaxation technique such as deep breathing.

What should you not take with pantoprazole?

Do not use pantoprazole together with medicines containing rilpivirine (eg, Complera®, Edurant®, Odefsey®). Using these medicines together may cause unwanted side effects.

Why does everyone in the hospital get Protonix?

Many patients who are admitted into hospitals are put on proton pump inhibitors (PPIs) both to prevent gastrointestinal bleeding and as heartburn/gastroesophageal reflux disease relief after discharge.

How long can you take Protonix 40 mg?

Adults—40 milligrams (mg) once a day for up to 8 weeks. Your doctor may want you to take pantoprazole for more than 8 weeks for certain conditions.

What does Protonix do for your stomach?

It works by decreasing the amount of acid your stomach makes. This medication relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. It helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus.

What medications should not be taken with pantoprazole?

Do not use pantoprazole together with medicines containing rilpivirine (eg, Complera®, Edurant®, Odefsey®). Using these medicines together may cause unwanted side effects.

What are the side effects of pantoprazole?

Check with your doctor immediately if any of the following side effects occur while taking pantoprazole: Less common. Blurred vision. dry mouth. flushed, dry skin. fruit-like breath odor. increased hunger. increased thirst.

What are the symptoms of predisposed patients?

Confusion, depression, hallucinations, and disorientation, especially in predisposed patients, occurred with use, and was aggravated in patients with preexisting conditions. [ Ref]

Does pantoprazole need immediate medical attention?

Side effects not requiring immediate medical attention. Some side effects of pantoprazole may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine.

Is headache a side effect of tetracycline?

Headache was a very commonly reported side effect in pediatric patients 2 to 16 years of age. In adults, headache occurred most frequently in patients given quadruple therapy (pantoprazole, bismuth, metronidazole, tetracycline) for H pylori infections, but was also very common in triple therapy (pantoprazole, amoxicillin, clarithromycin ).

Does H pylori cause anorexia?

Anorexia commonly occurred in patients with H pylori. [ Ref]

Does Protonix IV cause diarrhea?

Diarrhea occurred most frequently in patients given quadruple therapy (pantoprazole (the active ingredient contained in Protonix IV) bismuth, metronidazole, tetracycline) for Helicobacter pylori infections, but was also very common in triple therapy (pantoprazole, amoxicillin, clarithromycin).

If experienced, these tend to have a Severe expression i

Sorry, we have no data available. Please contact your doctor or pharmacist.

If experienced, these tend to have a Severe expression i

Sorry, we have no data available. Please contact your doctor or pharmacist.

Are you currently using Protonix?

This survey is being conducted by the WebMD marketing sciences department.

What is delayed release protonix?

What Is Protonix? Protonix Delayed-Release Oral Suspension and Delayed-Release Tablets (pantoprazole sodium) is a proton pump inhibitor (PPI) used for short-term treatment (less than 10 days) of gastroesophageal reflux disease ( GERD) and a history of erosive esophagitis in adult patients.

What are the side effects of pantoprazole?

sudden pain or trouble moving your hip, wrist, or back; bruising or swelling where intravenous pantoprazole was injected; kidney problems -- fever, rash, nausea, loss of appetite, joint pain, urinating less than usual, blood in your urine, weight gain;

How long does pantoprazole cause nausea?

If you use pantoprazole for longer than 3 years, you could develop a vitamin B-12 deficiency. Talk to your doctor about how to manage this condition if you develop it. Common side effects may include: headache, dizziness; stomach pain, gas, nausea, vomiting, diarrhea; joint pain; or.

Can you take Protonix while pregnant?

Protonix During Pregnancy and Breastfeeding. Protonix is not expected to be harmful to a fetus. Tell your doctor if you are pregnant or plan to become pregnant during treatment with Protonix. Protonix passes into breast milk and may harm a nursing baby. Consult your doctor before breastfeeding.

Does Protonix interact with other medications?

Protonix may interact with atazanavir, nelfinavir, ampicillin, blood thinners, digoxin, diuretics (water pills), ketoconazole, iron, or methotrexate. Tell your doctor all medications and supplements you use.

Can you estimate the frequency of adverse reactions to protonix?

Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

Is Protonix safe for GERD?

Safety of PROTONIX in the treatment of EE associated with GERD was evaluated in pediatric patients ages 1 year through 16 years in three clinical trials. Safety trials involved pediatric patients with EE; however, as EE is uncommon in the pediatric population, 249 pediatric patients with endoscopically-proven or symptomatic GERD were also evaluated. All adult adverse reactions to PROTONIX are considered relevant to pediatric patients. In patients ages 1 year through 16 years, the most commonly reported (>4%) adverse reactions include: URI, headache, fever, diarrhea, vomiting, rash, and abdominal pain.

What are the side effects of Protonix?

Less Serious Side Effects of Protonix. Headache. Diarrhea.

How long does Protonix last?

Doctors may also prescribe Protonix for long-term use to treat excess stomach acid. Long-term treatment is anything lasting more than eight weeks. There is no research on the effects of taking Protonix for more than 12 months.

What is protonix used for?

Protonix (pantoprazole sodium) is a drug in a class of powerful acid-suppressing medications called proton pump inhibitors (PPIs). These medicines can cause rare but life-threatening side effects. Protonix is one of several PPIs named in lawsuits over serious kidney conditions. By Terry Turner. Edited By Emily Miller.

What is the generic name for Protonix?

The generic name for Protonix is pantoprazole. Pfizer’s patent on pantoprazole ran out in 2010. The FDA approved the first generic versions of pantoprazole that same year. The agency has approved several generic pantoprazole applications since then. All generic versions require a prescription.

Is Protonix still taking cases?

Protonix lawyers are still taking new cases. They expect to file thousands more PPI lawsuits before the first case goes to trial.

Does Protonix cause kidney problems?

Studies dating back to the 1990s have linked PPIs like Protonix to kidney problems. Protonix kidney side effects may include kidney damage or injury.

Can Protonix cause side effects?

Protonix side effects include rare but serious conditions. Serious PPI side effects most often result from long-term use.

How long can you take Protonix IV?

Protonix IV injection should only be given by intravenous infusion for a maximum of 7 to 10 days. Discontinue the IV infusion as soon as the patient can swallow the tablets or receive the oral suspension. Protonix is available as a generic under the name pantoprazole. 3.

What medications interact with Protonix?

Common medications that may interact with Protonix include: aminophylline or theophylline. ampicillin.

What is Protonix 2021?

Medically reviewed by Carmen Fookes, BPharm. Last updated on March 29, 2021. 1. How it works. Protonix is a brand (trade) name for pantoprazole. Pantoprazole works by reducing the production of stomach acid by irreversibly blocking the actions of an enzyme responsible for acid production, ...

How does pantoprazole work?

Pantoprazole works by reducing the production of stomach acid by irreversibly blocking the actions of an enzyme responsible for acid production, called H+/K+ ATPase (also known as the gastric proton pump). The proton pump is located in the parietal cells of the stomach wall.

What class is Protonix?

Protonix belongs to the class of medicines known as proton pump inhibitors (PPIs).

Can Protonix cause nephritis?

Administration of PPIs (such as Protonix), has been associated with acute interstitial nephritis, a severe inflammation of the kidneys. May occur on medication initiation or at any point of therapy. Symptoms include fever, rash, and generalized aches and pains. Discontinue Protonix and seek medical advice.

Where is the proton pump located?

The proton pump is located in the parietal cells of the stomach wall. Both baseline gastric acid secretion and stimulated gastric acid secretion are affected; the degree that they are affected depends upon the dose of pantoprazole. This allows damaged tissue in the esophagus, stomach, and duodenum to heal.

What are the side effects of pantoprazole?

Check with your doctor immediately if any of the following side effects occur while taking pantoprazole: Less common. Blurred vision. dry mouth. flushed, dry skin. fruit-like breath odor. increased hunger. increased thirst.

What are the side effects of a syringe?

Side effects not requiring immediate medical attention 1 Belching 2 bloated or full feeling 3 excess air or gas in the stomach or bowels 4 passing gas 5 trouble sleeping

What are the symptoms of predisposed patients?

Confusion, depression, hallucinations, and disorientation, especially in predisposed patients, occurred with use, and was aggravated in patients with preexisting conditions. [ Ref]

Does pantoprazole cause diarrhea?

Diarrhea occurred most frequently in patients given quadruple therapy (pantoprazole, bismuth, metronidazole, tetracycline) for Helicobacter pylori infections, but was also very common in triple therapy (pantoprazole, amoxicillin, clarithromycin).

Is headache a side effect of tetracycline?

Headache was a very commonly reported side effect in pediatric patients 2 to 16 years of age. In adults, headache occurred most frequently in patients given quadruple therapy (pantoprazole, bismuth, metronidazole, tetracycline) for H pylori infections, but was also very common in triple therapy (pantoprazole, amoxicillin, clarithromycin ).

Does H pylori cause anorexia?

Anorexia commonly occurred in patients with H pylori. [ Ref]

Does pantoprazole need immediate medical attention?

Side effects not requiring immediate medical attention. Some side effects of pantoprazole may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine.

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For The Consumer

  • Applies to pantoprazole: oral packet, oral tablet delayed release, oral tablet enteric coated Other dosage forms: 1. intravenous powder for solution
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For Healthcare Professionals

  • Applies to pantoprazole: intravenous powder for injection, oral delayed release tablet, oral granule enteric coated
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Frequently Asked Questions

Further Information

  • Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Some side effects may not be reported. You may report them to the FDA. Medical Disclaimer
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