Applications of Suspensions:
- 1. It is usually applicable for a drug that is insoluble or poorly soluble e.g. Prednisolone syrup.
- 2. To prevent degradation of drug or to remove stability of drug e.g. Oxytetracycline suspension.
- 3. To mask the bitter drug. e.g. Chloramphenicol palmitate.
- 4. Topical application e.g. Calamine lotion is used.
- 5. Parenteral applications for control rate of drug absorption e.g. Penicillin procaine.
What are the examples of pharmaceutical suspension?
Examples of Pharmaceutical SuspensionsAntacid oral suspensions Antibacterial oral suspension.Dry powders for oral suspension (antibiotic)Analgesic oral suspension.Anthelmentic oral suspension.Anticonvulsant oral suspension.Antifungal oral suspension.
What is suspension in pharmaceutical chemistry?
Definition. ➢ A Pharmaceutical suspension is a coarse dispersion in which internal phase (therapeutically active ingredient)is dispersed uniformly throughout the external phase.
What are 3 types of suspension in pharmacy?
Based on the route of administration, suspensions can be classified as oral, topical, ophthalmic, otic, or nasal suspensions.
Why are suspensions important in medicine?
Pharmaceutical suspensions may serve as an alternative means used to administer drugs to children including paediatric and geriatric patients and older patients who have difficulty swallowing solid dosage forms. 4. Drug in suspension exhibits higher rate of bioavailability than other dosage forms.
What are the applications of suspensions give example?
Ans: Common examples of suspension include the mixture of chalk and water, muddy water, the mixture of flour and water, a mixture of dust particles and air, fog, milk of magnesia, etc.
What are the 10 examples of suspension?
Examples of SuspensionsMud in Water.Turpentine oil in paint dyes.Chalk in water.Slaked lime for whitewashing.Milk of magnesia.Sand particles suspended in the water.Kimchi suspended on vinegar.
What are the two types of suspension in pharmacy?
Suspensions can be classified into flocculated and deflocculated suspension based on the electrokinetic nature of the dispersed phase.
What are the advantages of suspension system?
Specifically, the suspension system maximizes the friction between the tires and the road to provide steering stability and good handling. The suspension system also provides comfort for passengers to limiting the impact of particular road conditions to not only the car, but the passengers riding inside.
What is suspension and its advantages?
A suspension is a dosage form that can improve the chemical stability of certain drugs. Like Procaine penicillin G. Suspension can improve the taste of various unpleasant/bitter tastes of the drug by masking them.
What is better for a pharmaceutical a solution or suspension?
A suspension could be a means to provide a higher dose of a medication than could be completely dissolved into solution.
What are advantages and disadvantages of suspension?
Comparison Table of Advantages and Disadvantages of SuspensionAdvantages of suspensionDisadvantages of suspensionHigher concentration of drugThe accurateness of the dose is not possibleIt can improve the taste or odour of the drugsIt is bulkySpan and the onset of action of dose can be controlled2 more rows•May 9, 2022
What is a suspension formulation?
The suspension is a biphasic liquid or semi-solid dosage form where the finely divided insoluble solid drug particles are homogeneously dispersed in a liquid or semi-solid medium. The solid drug particles act here as the dispersed phase and the liquid or the semi-solid as the dispersion medium.
What do u mean by suspension?
Definition of suspension 1 : the act of suspending : the state or period of being suspended: such as. a : temporary removal (as from office or privileges) b : temporary withholding (as of belief or decision) c : temporary abrogation of a law or rule.
What is suspension mixture example?
Suspension is commonly represented by a mixture of chalk and water, muddy water, a mixture of flour and water, a mixture of dust particles and air, fog, milk of magnesia, and so on.
What is suspension formulation?
The suspension is a biphasic liquid or semi-solid dosage form where the finely divided insoluble solid drug particles are homogeneously dispersed in a liquid or semi-solid medium. The solid drug particles act here as the dispersed phase and the liquid or the semi-solid as the dispersion medium.
What is suspension classification?
Most suspensions are classified as a coarse suspension which is a dispersion of particles with a mean diameter greater than 1µm (1 to 100 µm. A colloidal suspension is a dispersion of particles with a mean diameter of less than 1µm (0.5µm to 1µm).
What is a pharmaceutical suspension?
A pharmaceutical suspension is a coarse dispersion in which the internal phase (the active ingredient) is placed/distributed uniformly throughout the external phase/continuous phase.
Why is suspension used in parentral application?
Suspension can be formulated for parentral application in order to control rate of drug absorption.E .g. penicillin procaine
What are the two groups of suspensions?
Suspensions can be divided into two groups as flocculated suspensions and deflocculated suspensions based on the electro-kinetic nature of solid particles that are suspended in the suspension.
What is flocculated suspension?
A flocculated suspension is a suspension in which particles of the suspension has undergone flocculation. A flocculated suspension is composed of large aggregates (flocks) and this type of suspension will lead to a rapid rate of sedimentation.
What is the purpose of oxy tetracycline suspension?
To prevent degradation of drug or to improve stability of drug; E.g. Oxy tetracycline suspension
What is a suspension in medical terms?
Suspensions are a class of dispersed systems (Heterogenous systems) in which a finely divided solid is dispersed uniformly in a liquid dispersion medium. or A pharmaceutical suspension may be defined as a coarse dispersion of biphasic liquid dosage form containing finely divided insoluble material suspended in a liquid medium.
Where is suspension given?
Suspension dosage forms are given by the oral route, injected intramuscularly or subcutaneously, instilled intranasally, inhaled into the lungs, applied to the skin as topical preparations, or used for ophthalmic or otic purposes in the eye or ear, respectively.
What is a suspension in pharmaceuticals?
Pharmaceutical suspension is a liquid dosage form containing finely divided, undissolved drug particles dispersed throughout a liquid vehicle in which the drug exhibits a minimum degree of solubility. This dosage form is used for providing a liquid dosage form for insoluble drugs. In an ideal suspension, particles are uniformly dispersed ...
Which order is the drug in suspension?
Bioavailability is in following order, Solution > Suspension > Capsule > Compressed Tablet > Coated tablet.
Why is suspension so unstable?
Pharmaceutical suspensions are fundamentally unstable and for this reason, it requires formulation skill to ensure that the physical stability of the formulation is retained over the period of the shelf-life. 2. Aesthetic pharmaceutical suspension is difficult to formulate that is they lack elegance. 3.
Is aesthetic suspension difficult to formulate?
2. Aesthetic pharmaceutical suspension is difficult to formulate that is they lack elegance.
Do particles disperse after sedimentation?
In an ideal suspension, particles are uniformly dispersed and remain so even after prolonged periods of time. Even if sedimentation occurs, particles should readily redisperse upon mild agitation of the container.
Can penicillin be improved?
6. Chemical stability of certain drugs e.g., Procaine penicillin G can be improved when formulated as suspensions.
Is suspension a ready to use medication?
Most suspensions are available in ready-to-use form from the manufacturer. In cases of physical or chemical incompatibility, they are marketed as reconstitutable medications in unit-dose sachet or multidose bottles. This article focuses on the advantages and disadvantages of pharmaceutical suspensions.
