what are the side effects of cefotaxime

What is cefotaxime for injection?

Cefotaxime for injection is a cephalosporin antibiotic used to treat a variety of bacterial infections. Cefotaxime is available in generic form. What Are Side Effects of Cefotaxime? colitis. Less common side effects of cefotaxime include:

What should I know about Cefpodoxime before taking it?

Check with your doctor immediately if any of the following side effects occur while taking cefpodoxime: Some side effects of cefpodoxime may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine.

What happens if I overdose on cefotaxime (Claforan)?

What happens if I overdose on Cefotaxime (Claforan)? Overdose symptoms may include weakness, cold feeling, pale skin, blue lips, or seizure (convulsions). If you think you or someone else may have overdosed on: Cefotaxime (Claforan), call your doctor or the Poison Control center (800) 222-1222

Does Cefpodoxime cause diarrhea and loose stools?

[ Ref] Diarrhea and loose stools may be dose-related and has been reported in 10.4% of patients taking 800 mg cefpodoxime per day, compared to 5.7% of patients taking 200 mg per day. Ten percent of these patients tested positive Clostridium difficile organisms or toxins.

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How long can cefotaxime be used?

The duration of the treatment depends on the course of the disease. As a general rule Cefotaxime is administered for a further 3 to 4 days after improvement/regression of the symptoms. Adults and children over 12 years in general receive 1 g Cefotaxime every 12 hours.

Is cefotaxime a strong antibiotic?

As a β-lactam antibiotic in the third-generation class of cephalosporins, cefotaxime is active against numerous Gram-positive and Gram-negative bacteria, including several with resistance to classic β-lactams such as penicillin.

What is cefotaxime drug used for?

Cefotaxime is a third generation cephalosporin used to treat susceptible Gram negative and Gram positive bacterial infections. Cefotaxime is a third-generation cephalosporin antibiotic.

What are the contraindications of cefotaxime?

Hypersensitivity to cefotaxime is an absolute contraindication to its use. Patients who have known allergies to penicillin or other cephalosporins should also avoid cefotaxime.

What is the strongest antibiotic for bacterial infection?

Vancomycin, long considered a "drug of last resort," kills by preventing bacteria from building cell walls. It binds to wall-building protein fragments called peptides, in particular those that end with two copies of the amino acid D-alanine (D-ala).

What is the other name for cefotaxime?

Sterile CLAFORAN (cefotaxime sodium) is a semisynthetic, broad spectrum cephalosporin antibiotic for parenteral administration.

How often should you take cefotaxime?

The usual dosage range is 100-150mg/kg/day in two to four divided doses. However, in very severe infection doses of up to 200mg/kg/day may be required. Neonates: The recommended dosage is 50mg/kg/day in two to four divided doses. In severe infections 150-200mg/kg/day, in divided doses, have been given.

Is cefotaxime still available?

Cefotaxime for Injection is available only by prescription in the U.S. Please refer to the package insert for the FDA-approved Cefotaxime for Injection drug product for full prescribing information.

Which is better cefotaxime or ceftriaxone?

Both ceftriaxone and cefotaxime are effective in the treatment of bacterial meningitis, but ceftriaxone has the advantage of being administered as a single daily dose6.

What drugs interact with cefotaxime?

Most frequently checked interactionsAcetylsalicylic Acid (aspirin)Adrenalin (epinephrine)Augmentin (amoxicillin / clavulanate)B Complex 100 (multivitamin)Calcium 600 D (calcium / vitamin d)Chlorpheniramine (Allergy) (chlorpheniramine)Cipro (ciprofloxacin)Co-trimoxazole (sulfamethoxazole / trimethoprim)More items...

What is the meaning of cefotaxime?

A third generation semisynthetic cephalosporin antibiotic with bactericidal activity.

What is sepsis infection caused by?

Bacterial infections cause most cases of sepsis. Sepsis can also be a result of other infections, including viral infections, such as COVID-19 or influenza, or fungal infections.

How often should you take cefotaxime?

The usual dosage range is 100-150mg/kg/day in two to four divided doses. However, in very severe infection doses of up to 200mg/kg/day may be required. Neonates: The recommended dosage is 50mg/kg/day in two to four divided doses. In severe infections 150-200mg/kg/day, in divided doses, have been given.

Which is better cefotaxime or ceftriaxone?

Both ceftriaxone and cefotaxime are effective in the treatment of bacterial meningitis, but ceftriaxone has the advantage of being administered as a single daily dose6.

Why is cefotaxime favored over ceftriaxone?

Cefotaxime is recommended over ceftriaxone because ceftriaxone may cause bilirubin displacement, potentially leading to serious adverse events associated with unconjugated hyperbilirubinemia such as kernicterus.

Which organism is resistant to cefotaxime?

Microbiology. The predominant cefotaxime-resistant organism was Pseudomonas aeruginosa. Escherichia coli and Enterobacter spp. were the next most-common isolates resistant to cefotaxime.

What are the side effects of cephalosporins?

Hepatic side effects have included increased AST, ALT, GGT, alkaline phosphatase, bilirubin, and LDH. These changes have generally been transient and clinically insignificant. Acute liver injury has been reported during postmarketing experience. Cephalosporins as a class have been associated with hepatic dysfunction including cholestasis. [ Ref]

What are the side effects of a hematocrit test?

Hematologic side effects have included anemia (less than 1%), leukocytosis, lymphocytosis, granulocytosis, basophilia, monocytosis, thrombocytosis, decreased hemoglobin, decreased hematocrit, leukopenia, lymphocytopenia, thrombocythemia, neutropenia, thrombocytopenia and eosinophilia, positive Coombs' test, and prolonged PT and PTT. Most of these effects were transient and clinically insignificant. Easy bleeding or bruising has been reported. Cephalosporins as a class have been associated with aplastic anemia, hemolytic anemia, prolonged prothrombin time, hemorrhage, neutropenia, pancytopenia, and agranulocytosis. [ Ref]

What are the side effects of a syringe?

swelling of the abdominal or stomach area. swelling or inflammation of the mouth. swollen, red, or tender area of infection. trouble with sleeping. unable to sleep. white patches in the mouth, tongue, or throat. Managing side effects (general information)

Does cefpodoxime need medical attention?

Side effects not requiring immediate medical attention. Some side effects of cefpodoxime may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine.

Does cephalosporin cause renal dysfunction?

Purpuric nephritis has been reported during postmarketing experience. Cephalosporins as a class have been associated with renal dysfunction and toxic nephropathy. [ Ref]

Does C difficile cause withdrawal?

The symptoms associated with C difficile were mild and did not result in withdrawal from the study. The excretion of C difficile in the stool was not statistically associated with the passage of loose stools and none of the subjects went on to develop pseudomembranous colitis.

Does cefpodoxime cause side effects?

Along with its needed effects, cefpodoxime may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking cefpodoxime: More common. Diarrhea.

How is cefotaxime dose determined?

Dosage of cefotaxime is determined by susceptibility of the causative organisms, severity of the infection, and the condition of the patient.

What is cefotaxime used for?

What Is Cefotaxime? Cefotaxime for injection is a cephalosporin antibiotic used to treat a variety of bacterial infections. Cefotaxime is available in generic form.

What are the adverse reactions of cephalosporin?

In addition to the adverse reactions listed above which have been observed in patients treated with cefotaxime (cefotaxime for injection) sodium, the following adverse reactions and altered laboratory tests have been reported for cephalosporin class antibiotics: allergic reactions, hepatic dysfunction including cholestasis, aplastic anemia, hemorrhage, and false-positive test for urinary glucose.

What are the side effects of a syringe?

Common side effects may include: 1 pain, bruising, swelling, or other irritation where the injection was given; 2 diarrhea; 3 fever; or 4 rash, itching.

What is the FDA's number for side effects?

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

When does pseudomembrane colitis appear?

Symptoms of pseudomembranous colitis can appear during or after antibiotic treatment.

Does cefotaxime interact with antibiotics?

Cefotaxime may interact with aminoglycoside antibiotics. Tell your doctor all medications and supplements you use.

What Is Cefotaxime and How Does It Work?

Cefotaxime is a prescription medication used to treat the symptoms of Gonococcal Urethritis / Cervicitis, Gonorrhea, Rectal, Infections Caused by Susceptible Organisms, and prophylaxis of surgical infection .

What other drugs interact with Cefotaxime?

If your medical doctor is using this medicine to treat your pain, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider, or pharmacist first

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Sorry, we have no data available. Please contact your doctor or pharmacist.

Are you currently using cefotaxime SODIUM vial?

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Why do you need cefotaxime?

A healthcare provider will give you this injection when cefotaxime is used to prevent infection from surgery.

How long can you keep cefotaxime in the refrigerator?

After mixing cefotaxime with a diluent, you may need to store the mixture in a refrigerator and use it within a certain number of days. What should I do if I missed a dose of Cefotaxime (Claforan)? Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose.

What is the brand name of Claforan?

Brand Names: Claforan, Claforan ADD-Vantage. Last Updated: June 23, 2020. Cefotaxime is a cephalosporin (SEF a low spor in) antibiotic. Cefotaxime is used to treat many kinds of bacterial infections, including severe or life-threatening forms. Cefotaxime is also used to prevent infection in people having certain types of surgery.

What are the symptoms of overdose?

Overdose symptoms may include weakness, cold feeling, pale skin, blue lips, or seizure (con vulsions). If you think you or someone else may have overdosed on: Cefotaxime (Claforan) , call your doctor or the Poison Control center. (800) 222-1222. If someone collapses or isn't breathing after taking Cefotaxime (Claforan), call 911.

What is the FDA's number for side effects?

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Can you take Cefotaxime with a viral infection?

Skipping doses can increase your risk of infection that is resistant to medication. Cefotaxime will not treat a viral infection such as the flu or a common cold.

Can you mix cefotaxime with a liquid?

Ask your doctor or pharmacist if you don't understand all instructions. Cefotaxime must be mixed with a liquid (diluent) before using it. You may need to further dilute the mixed medicine before injecting your dose.