Common side effects may include: burning, itching, or irritation of treated skin; dry or cracking skin; redness or crusting around your hair follicles; spider veins; stretch marks; acne; or temporary hair loss.
- Burning sensation of the skin.
- dry skin.
- flushing or redness of the skin.
- itching, scaling, severe redness, soreness, or swelling of the skin.
- skin irritation.
- skin rash, encrusted, scaly and oozing.
What are the long-term effects of clobetasol propionate?
An overdose of clobetasol topical is not expected to produce life threatening symptoms. Long term use of high doses can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.
What are the most common clobetasol side effects?
What are the risks and warnings for clobetasol (Clobex)?
- SKIN INFECTIONS. Clobetasol (Clobex) can lower your body's ability to fight infections, including infections on your skin.
- SKIN REACTIONS. ...
- CHANGE IN HORMONES. ...
- HIGH BLOOD SUGAR. ...
What conditions does clobetasol propionate treat?
Clobetasol propionate is a topical corticosteroid preparation usually found in the form of cream, ointment, gel or shampoo. It is used on the skin or scalp to treat common dermatological disorders such as eczema and psoriasis. Its main effect is to reduce the swelling, inflammation, redness and itching associated with skin conditions such as these.
Can clobetasol propionate cause cancer?
Summary: Breast cancer is found among people who take Clobetasol propionate, especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months. The phase IV clinical study analyzes which people take Clobetasol propionate and have Breast cancer.
Is clobetasol propionate harmful to the skin?
Do not put clobetasol on your face unless your doctor says it's OK. It can make some skin problems on the face worse. Clobetasol (including scalp treatment and shampoo) is a very strong steroid. Clobetasol can also be combined with an antibiotic (neomycin sulfate) and an antifungal (nystatin).
How long do I leave clobetasol on?
If you are using clobetasol propionate shampoo, use it as you normally would use a shampoo but leave it on your scalp for 15 minutes before rinsing out. Avoid contact with the lips and eyes.
What are side effects of clobetasol propionate?
Side EffectsBurning, stinging, itching, irritation, dryness, or redness may occur when this medication is first applied to the skin. ... Tell your doctor right away if you have any serious side effects, including: stretch marks (striae), skin thinning/discoloration, excessive hair growth, acne, hair bumps (folliculitis).More items...
Can clobetasol get into your bloodstream?
Rarely, it is possible this medication will be absorbed from the skin into the bloodstream.
How do you know if clobetasol is working?
Official answer. It takes about one to three days for clobetasol propionate to start working when it is being used to treat eczema. Some improvement in symptoms such as inflammation (redness) and itching, should be noticed within this time.
Do you have to wash off clobetasol?
Do not use it on skin areas that have cuts, scrapes, or burns. If it does get on these areas, rinse it off right away with water. To help clear up your skin or scalp problem completely, it is very important that you keep using this medicine for the full time of treatment.
What happens if you use too much clobetasol?
Using too much of this medicine or using it for a long time may increase your risk of having adrenal gland problems. The risk is greater for children and patients who use large amounts for a long time.
What can I use instead of clobetasol propionate?
Alternatives for Clobex lotioncorticosteroids other than Clobex, such as: mometasone furoate lotion (Elocon) hydrocortisone 2.5% lotion.retinoid cream or gel, such as tazarotene (Tazorac)calcineurin inhibitors, such as: tacrolimus ointment (Protopic) pimecrolimus cream (Elidel)
Can clobetasol affect sleep?
sleep problems (insomnia), weight gain, puffiness in your face, muscle weakness, or.
Does clobetasol raise blood pressure?
Symptoms can include high blood sugar and high blood pressure. Skin reactions warning: This drug may cause skin reactions. These include acne, inflammation of your hair follicles, color changes, rashes, infections, allergic reactions, and other problems.
How long does it take for clobetasol to work?
Clobetasol propionate and other potent corticosteroids are a common treatment for psoriasis. Research suggests that clobetasol propionate generally works well to clear or nearly clear psoriasis patches within 2–4 weeks.
Does clobetasol make you gain weight?
Weight gain is not a common side effect of clobetasol. Sudden weight gain when using clobetasol can be a sign of a serious problem and requires immediate medical attention. Similarly, changes in the way body fat is distributed can be another sign of a serious side effect.
What happens if you use too much clobetasol?
Using too much of this medicine or using it for a long time may increase your risk of having adrenal gland problems. The risk is greater for children and patients who use large amounts for a long time.
How long does it take clobetasol propionate to work?
Clobetasol propionate and other potent corticosteroids are a common treatment for psoriasis. Research suggests that clobetasol propionate generally works well to clear or nearly clear psoriasis patches within 2–4 weeks.
Does clobetasol stop itching?
Descriptions. Clobetasol topical is used to help relieve redness, itching, swelling, or other discomfort caused by certain skin conditions.
Can clobetasol cause more itching?
More common side effects The most common side effects of clobetasol include: burning, irritation, and itching of the skin where you applied the drug.
Does Clobetasol need medical attention?
Side effects not requiring immediate medical attention. Some side effects of clobetasol topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine.
Does Clobetasol cause side effects?
Side effects requiring immediate medical attention. Along with its needed effects, clobetasol topical may cause some unwanted effects . Although not all of these side effects may occur, if they do occur they may need medical attention.
Can medicine cause side effects?from mayoclinic.org
Side Effects. Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur:
Does Clobetasol need medical attention?from drugs.com
Side effects not requiring immediate medical attention. Some side effects of clobetasol topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine.
Does Clobetasol cause side effects?from drugs.com
Side effects requiring immediate medical attention. Along with its needed effects, clobetasol topical may cause some unwanted effects . Although not all of these side effects may occur, if they do occur they may need medical attention.
What symptoms does clobetasol propionate relieve?from drugs.com
Clobetasol propionate reduces inflammation (redness) and itching and can also relieve dryness, crusting, scaling, and discomfort caused by various skin conditions.
What is Clobetasol used for?from verywellhealth.com
As a high-strength topical steroid, clobetasol is meant to be used as a short-term treatment to quickly improve dermatitis rash flares.
How old do you have to be to take Clobetasol?from verywellhealth.com
Clobetasol should not be used by children under the age of 12 years old (18 years old in the case of the brand Impoyz). Children absorb more of this medication through their skin (per their body size) than do adults, so they are more likely to experience side effects. Children younger than 12 years old often do better with less-potent topical ...
Why does my skin absorb so much medication?from verywellhealth.com
It's possible to absorb enough of this medication through the skin to cause: Cushing's syndrome.
Can Clobetasol be used for rosacea?from verywellhealth.com
You may be instructed to apply this medication less often, or to use it for shorter periods of time. Clobetasol shouldn't be used to treat rosacea or perioral dermatitis. Topical steroids can make these skin conditions worse.
Does Clobetasol cause side effects?from drugs.com
Side effects requiring immediate medical attention. Along with its needed effects, clobetasol topical may cause some unwanted effects . Although not all of these side effects may occur, if they do occur they may need medical attention.
Can you use Clobetasol as a moisturizer?from verywellhealth.com
Doing so won't clear up your rash any faster, but it does raise the chance of developing side effects. Also, don't use this medication as a moisturizer. If your skin feels dry between uses, it's OK to use a non-medicated, over-the-counter moisturizing cream. Store clobetasol at room temperature.
How long does it take for clobetasol to get out of your system?
Some researchers have found that suppression of cortisol levels is still apparent 96 hours after topical use of this medicine, which implies that clobetasol can stay in your system for long periods of time, possibly for up to a few weeks. Clobetasol is not recommended to be used for more than two consecutive weeks.
Can clobetasol cause weight gain?
Weight gain is not a common side effect of clobetasol. Sudden weight gain when using clobetasol can be a sign of a serious problem and requires immediate medical attention. Similarly, changes in the way body fat is distributed can be another sign of a serious side effect.
Can topical steroids cause anxiety?
Tell your family and loved ones that treatment with cortisone can cause mood disorders such as irritability, anxiety or even a sense of euphoria. This can help them understand your mood swings and behaviour. If these symptoms become severe, immediately consult a physician.
Can clobetasol propionate topical solution cause hair loss?
Hair loss or hair thinning may also occur, but this is a very rare side effect and is estimated to occur in only 1 out of every 300 people who use clobetasol. Clobetasol is a potent topical steroid and is not a good option for hair and scalp conditions that are not associated with inflammation.
Do you wash out clobetasol propionate solution?
If you are using clobetasol propionate shampoo, use it as you normally would use a shampoo but leave it on your scalp for 15 minutes before rinsing out. Avoid contact with the lips and eyes.
How are you supposed to apply clobetasol?
Apply or spray a thin layer of this medicine to the affected area of the skin. Rub it in gently. With the lotion, protect the skin from water, clothing, or anything that causes rubbing until the medicine has dried. Also, shake the lotion well before using it.
How long can you use clobetasol propionate?
Use this medication only for the condition prescribed. Do not use for longer than 4 weeks unless directed by your doctor. If no improvement occurs in 2 weeks of treatment with clobetasol, or if your condition worsens, stop using this medication and inform your doctor.
What is clobetasol topical solution?
The corticosteroids are a class of compounds comprising steroid hormones secreted by the adrenal cortex and their synthetic analogs. In pharmacologic doses, corticosteroids are used primarily for their anti-inflammatory and/or immunosuppressive effects.
How many times is clobetasol propionate used?
These doses are approximately 0.02 and 0.05 times, respectively, the human topical dose of clobetasol propionate topical solution. Abnormalities seen included cleft palate, cranioschisis, and other skeletal abnormalities. There are no adequate and well-controlled studies of the teratogenic potential of clobetasol propionate in pregnant women.
What is 0.05% clobetasol propionate?
Clobetasol Propionate Topical Solution USP, 0.05% contains the active compound clobeta sol propionate, a synthetic corticosteroid, for topical dermatologic use. Clobetasol, an analog of prednisolone, has a high degree of glucocorticoid activity and a slight degree of mineralocorticoid activity.
How to use Clobetasol?
Patients using clobetasol propionate topical solution should receive the following information and instructions: 1 This medication is to be used as directed by the physician and should not be used longer than the prescribed time period. It is for external use only. Avoid contact with the eyes. 2 This medication should not be used for any disorder other than that for which it was prescribed. 3 The treated skin area should not be bandaged or otherwise covered or wrapped so as to be occlusive. 4 Patients should report any signs of local adverse reactions to the physician.
What are the effects of corticosteroids on children?
Manifestations of adrenal suppression in children include low plasma cortisol levels and an absence of response to ACTH stimulation. Manifestations of intracranial hypertension include bulging fontanelles, headaches, and bilateral papilledema.
Where are topical corticosteroids metabolized?
Corticosteroids are bound to plasma proteins in varying degrees. Corticosteroids are metabolized primarily in the liver and are then excreted by the kidneys. Some of the topical corticosteroids, including clobetasol propionate and its metabolites, are also excreted into the bile.
What are the adverse events of corticosteroids?
Less frequent adverse events were itching and tightness of the scalp, dermatitis, tenderness, headache, hair loss, and eye irritation, each of which occurred in 1 of 294 patients. The following local adverse reactions are reported infrequently when topical corticosteroids are used as recommended.
What is clobetasol used for?
Uses. Clobetasol is used to treat certain scalp and skin conditions (e.g., psoriasis, dermatitis, rash ). Clobetasol reduces the swelling, itching and redness that can occur in these types of conditions. This medication is a very strong (super-high-potency) corticosteroid.
Where to report side effects?
You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. Precautions.
How long does it take for a stinging scalp to go away after taking a sulfate?
Tell your doctor if your condition lasts or gets worse after 2 weeks. Side Effects. Burning, stinging, itching, irritation, dryness, or redness may occur when this medication is first applied to the scalp/ skin. This should disappear in a few days as your body adjusts to the medication.
Can you take clobetasol if you are allergic to it?
Before using clobetasol, tell your doctor or pharmacist if you are allergic to it; or to any other steroids (e.g., hydrocortisone, dexamethasone); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Can corticosteroid cause skin infections?
Skin infections can become worse when using this medication. Tell your doctor if redness, swelling or irritation does not improve. Rarely, it is possible this medication will be absorbed from the skin into the bloodstream. This can lead to side effects of too much corticosteroid.
Are you currently using Clobetasol PROPIONATE Solution, Non-?
This survey is being conducted by the WebMD marketing sciences department.
Where to report side effects?
You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. Precautions.
What to tell your doctor before taking a sulfate med?
Before using this medication, tell your doctor or pharmacist your medical history, especially of: poor blood circulation, diabetes, other skin /scalp conditions (e.g., rosacea, perioral dermatitis ), immune system problems.
What to do if you miss a dose of a sulfate?
If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.
Can corticosteroid cause skin infections?
Skin infections can become worse when using this medication. Notify your doctor if redness, swelling or irritation does not improve. Rarely, it is possible this medication will be absorbed from the skin into the bloodstream. This can lead to side effects of too much corticosteroid.
Can you take clobetasol if you are allergic to it?
Precautions. Before using clobetasol, tell your doctor or pharmacist if you are allergic to it; or to any other steroids (e.g., hydrocortisone, dexamethasone); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.
Can you be allergic to clobetasol?
Before using clobetasol, tell your doctor or pharmacistif you are allergic to it; or to any other steroids(e.g., hydrocortisone, dexamethasone); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Can corticosteroid be absorbed from the skin?
Rarely, it is possible this medication will be absorbed from the skininto the bloodstream. This can lead to side effects of too much corticosteroid. These side effects are more likely in children, and in people who use this medication for a long time or over large areas of the skin. Tell your doctor right away if any of the following side effects occur: unusual/extreme tiredness, weight loss, headache, swelling ankles/feet, increased thirst/urination, visionproblems.
How many times is clobetasol propionate used?
These doses are approximately 0.02 and 0.05 times, respectively, the human topical dose of clobetasol propionate topical solution. Abnormalities seen included cleft palate, cranioschisis, and other skeletal abnormalities. There are no adequate and well-controlled studies of the teratogenic potential of clobetasol propionate in pregnant women.
What is the formula for clobetasol propionate?
Clobetasol propionate has the molecular formula C 25 H 32 ClFO 5 and a molecular weight of 466.98. It is a white to cream-colored crystalline powder insoluble in water.
Where are topical corticosteroids metabolized?
Corticosteroids are bound to plasma proteins in varying degrees. Corticosteroids are metabolized primarily in the liver and are then excreted by the kidneys. Some of the topical corticosteroids, including clobetasol propionate and its metabolites, are also excreted into the bile.
Does clobetasol propionate excrete into the bile?
Some of the topical corticosteroids, including clobetasol propionate and its metabolites, are also excreted into the bile. Following repeated nonocclusive application in the treatment of scalp psoriasis, there is some evidence that clobetasol propionate topical solution, 0.05% has the potential to depress plasma cortisol levels in some patients.
Can clobetasol be absorbed from skin?
As with all topical corticosteroids, clobetasol propionate can be absorbed from normal intact skin. Inflammation and/or other disease processes in the skin may increase percutaneous absorption. Occlusive dressings substantially increase the percutaneous absorption of topical corticosteroids (see DOSAGE AND ADMINISTRATION ).
Is clobetasol a dermatologic drug?
Clobetasol propionate, a corticosteroid, has been shown to have topical (dermatologic) and systemic pharmacologic and metabolic effects characteristic of this class of drugs.
Who should report local adverse reactions?
Patients should report any signs of local adverse reactions to the physician.
How long can you use Clobex cream?
Do not use Clobex® spray or Impoyz™ cream for more than 2 weeks unless your doctor told you to. To use the foam, scalp solution, or shampoo: Wash your hands with soap and water before and after using this medicine. Apply a thin layer of this medicine to the affected area of the scalp. Rub it in gently.
How to use a cream with a gel?
To use the cream, foam, gel, lotion, ointment, or spray: Wash your hands with soap and water before and after using this medicine. Apply or spray a thin layer of this medicine to the affected area of the skin. Rub it in gently.
For The Consumer
- Applies to clobetasoltopical: topical application cream, topical application emollient cream, topical application foam, topical application gel/jelly, topical application lotion, topical application ointment, topical application shampoo, topical application solution, topical application spray
For Healthcare Professionals
- Applies to clobetasol topical: compounding powder, topical cream, topical foam, topical gel, topical kit, topical lotion, topical ointment, topical shampoo, topical solution, topical spray
Frequently Asked Questions
Further Information
- Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Some side effects may not be reported. You may report them to the FDA. Medical Disclaimer