
Does Compazine cause weight gain?
dry mouth, stuffy nose; nausea, constipation; increased appetite, weight gain; blurred vision; agitation, feeling jittery, trouble sleeping; skin redness, itching, or rash; missed menstrual periods; or. impotence, abnormal ejaculation. This is not a complete list of side effects and others may occur.
Does Compazine Make you Sleepy?
Subsequently, question is, does compazine make you sleepy? SIDE EFFECTS: Drowsiness, dizziness, lightheadedness, blurred vision, constipation, or dry mouth may occur. Get medical help right away if you have any very serious side effects, including: seizures.
Can Compazine lower blood pressure?
The antiemetic benefits of Compazine are due to dopamine blockade in the chemoreceptor trigger zone of the brain. Compazine also has moderate effects on other neurotransmitters and receptors. changes in heart rhythm. low blood pressure. heart and liver abnormalities.
How often can you take Compazine for nausea?
medication we recommend taking first. You may take one 8 mg tablet every 6 hours. If your nausea does not go away 30 minutes after taking this medicine take the next prescribed medication, Compazine (#2). It does not cause drowsiness and other side effects are rare (possible headache, constipation or diarrhea).
What are the side effects of prochlorperazine?
What are the symptoms of overdose on prochlorperazine?
What are the extrapyramidal reactions?
What are the side effects of a syringe?
Can tricyclic antidepressants cause cardiovascular side effects?
Does prochlorperazine need medical attention?
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When should you not take Compazine?
Patients with bone marrow depression or who have previously demonstrated a hypersensitivity reaction (e.g., blood dyscrasias, jaundice) with a phenothiazine should not receive any phenothiazine, including prochlorperazine, unless in the judgment of the physician the potential benefits of treatment outweigh the possible ...
How long does Compazine stay in your system?
by Drugs.com Promethazine will be mostly out of your system in two to four days . The elimination half-life of a medication is the time it takes for blood levels of the medication to be reduced by half.
Is Compazine safe?
Compazine may cause serious side effects, including increased pressure in the eye and a muscle condition called Tardive dyskinesia. This is one of the reasons why many healthcare providers are prescribing newer anti-nausea medication instead of Compazine.
What are the negative effects of prochlorperazine?
Side EffectsAgitation.black, tarry stools.chest pain.clay-colored stools.decrease in how much or how often you urinate.difficulty in swallowing and breathing.dizziness, faintness, or lightheadedness when suddenly getting up from a lying or sitting position.drooling.More items...•
Why do you give Benadryl with Compazine?
The most frequently used dose of prochlorperazine is 10 mg given via IV or IM injection. Diphenhydramine (Benadrylâ) is routinely administered concomitantly with metoclopramide or prochlorperazine to decrease the risk of a patient developing anti-dopaminergic adverse effects.
Is Compazine good for anxiety?
Compazine (prochlorperazine) is a phenothiazine anti-psychotic used to treat psychotic disorders such as schizophrenia. Compazine (prochlorperazine) is also used to treat anxiety, and to control severe nausea and vomiting.
Who should not take Compazine?
Do not use prochlorperazine if you have recently used large amounts of alcohol or medicine that makes you sleepy. Prochlorperazine is not approved for use by anyone younger than 2 years old or weighing less than 20 pounds.
How long does it take for Compazine to work?
Key facts. Prochlorperazine starts to work in around 30 to 60 minutes. Common side effects include feeling sleepy and blurred vision. You can usually take prochlorperazine when you need it, up to 3 times a day.
What's the best anti nausea medicine?
Nausea medication One of the most popular over-the-counter (OTC) medicines for nausea, Pepto Bismol, contains an active ingredient called bismuth subsalicylate. “Bismuth subsalicylate works by protecting your stomach lining and reduces excess stomach acid to ease any discomfort,” Dr. Posina says.
When should you not take prochlorperazine?
Hypersensitivity to the active substance or to any of the excipients listed in section 6.1. Prochlorperazine should be avoided in patients with liver or renal dysfunction, Parkinson's disease, hypothyroidism, cardiac failure, phaeochromocytoma, myasthenia gravis, prostate hypertrophy.
What is the drug Compazine used for?
This medication is used to treat severe nausea and vomiting from certain causes (for example, after surgery or cancer treatment). Prochlorperazine belongs to a class of drugs known as phenothiazines.
What is the difference between Zofran and Compazine?
Zofran (ondansetron) and Compazine (prochlorperazine) are prescribed for the treatment of nausea and vomiting. Zofran is often used to prevent and treat nausea and vomiting during chemotherapy and after surgery. Compazine is also used to treat psychotic disorders such as schizophrenia and anxiety.
When does prochlorperazine wear off?
Following intramuscular injection, the antiemetic action is evident within 5 to 10 minutes and lasts for 3 to 4 hours.
How long after taking Compazine Can I take Zofran?
You may alternate this medicine with Zofran so you are taking an anti-nausea medicine every 3 hours. For example: – 6 a.m.: Take 1 tablet of Zofran – 9 a.m.: Take 1 tablet of Compazine – 12 p.m.: Take 1 tablet of Zofran – 3 p.m.: Take 1 tablet of Compazine Repeat in this order every 3 hours.
Is Compazine the same as Zofran?
Zofran and Compazine belong to different drug classes. Zofran is a selective 5-HT3 receptor antagonist and Compazine is a phenothiazine anti-psychotic.
How long does Compazine take to work?
Key facts. Prochlorperazine starts to work in around 30 to 60 minutes. Common side effects include feeling sleepy and blurred vision. You can usually take prochlorperazine when you need it, up to 3 times a day.
Common and Rare Side Effects for Compazine - WebMD
COMMON side effects If experienced, these tend to have a Severe expression i ; tardive dyskinesia, a disorder characterized by involuntary movements of the face, mouth and tongue
Side Effects of Compazine (Prochlorperazine), Warnings, Uses - RxList
SIDE EFFECTS. Drowsiness, dizziness, amenorrhea, blurred vision, skin reactions and hypotension may occur. Cholestatic jaundice has occurred. If fever with grippe-like symptoms occurs, appropriate liver studies should be conducted. If tests indicate an abnormality, stop treatment.
Dystonic reaction to compazine | Answers from Doctors | HealthTap
"i had a dystonic reaction to compazine two days ago. how long before i feel normal again and is this permanent?" Answered by Dr. Padmashri Rastogi: : I assume you had short notice use of compazine. Dystopia can last we...
Side Effects of Compazine (prochlorperazine) - MedicineNet
Compazine (prochlorperazine) is a prescription medication used to control nausea and vomiting, and is used as an antipsychotic medication for schizophrenia and psychotic disorders. Common side effects of Compazine include drowsiness, dizziness, missed menstrual periods (amenorrhea), blurred vision, skin reactions, and low blood pressure. Consult your doctor before taking Compazine if pregnant ...
Compazine (Prochlorperazine): Uses and Side Effects - Verywell Health
Compazine may also affect the pressure in the eye, and people who have glaucoma should always tell their healthcare provider before taking Compazine. This drug also carries a black box warning about using it in elderly patients who are experiencing psychosis and dementia; it is not approved for use in those patients because of a risk of death.
Compazine Oral: Uses, Side Effects, Interactions, Pictures ... - WebMD
Find patient medical information for Compazine oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.
How to report side effects of prescription drugs?
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Why do phenothiazines cause death?
In some cases, the cause appeared to be cardiac arrest or asphyxia due to failure of the cough reflex.
What is phenothiazine used for?
Phenothiazine antipsychotics are used when patients do not respond to other antipsychotics. The antiemetic benefits of Compazine are due to dopamine blockade in the chemoreceptor trigger zone of the brain. Compazine also has moderate effects on other neurotransmitters and receptors. changes in heart rhythm.
Can compazine be taken with potassium chloride?
Combining Compazine and potassium chloride may result in an increase in the ulcerogenic effect of potassium chloride. Combining Compazine with thalidomide may increase the risk of experiencing CNS depressant side effects. Compazine has not been adequately evaluated in pregnant women.
Can pregnant women take compazine?
Compazine has not been adequately evaluated in pregnant women. Due to the lack of conclusive safety data, Compazine should be avoided in pregnancy except in cases of severe nausea and vomiting that requires treatment and where the potential benefit justifies the potential risk to the fetus.
Does compazine affect blood levels?
Antacids may decrease the absorption of Compazine. Combining Compazine with other drugs that cause anticholinergic side effects such as dry mouth, constipation, dry eyes, decreased urinary output, and mental confusion increases the risk of experiencing these effects. Compazine may increase the blood levels of dofetilide.
Does compazine affect the heart?
heart and liver abnormalities. Drug interactions of Compazine include acetylcholinesterase inhibitors, which may decrease the effectiveness of Compazine. Combining Compazine with alcohol, kava kava, central nervous system (CNS) depressants, and cannabis may increase the risk of CNS depressant side effects.
What is compazine used for?
What Is Compazine? Compazine (prochlorperazine) is a phenothiazine anti-psychotic used to treat psychotic disorders such as schizophrenia. Compazine (prochlorperazine) is also used to treat anxiety, and to control severe nausea and vomiting.
What are the side effects of a syringe?
agitation, feeling jittery, trouble sleeping; skin redness, itching, or rash; missed menstrual periods; or. impotence, abnormal ejaculation. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Why do phenothiazines cause death?
In some cases, the cause appeared to be cardiac arrest or asphyxia due to failure of the cough reflex.
Can prochlorperazine be used during pregnancy?
During pregnancy, prochlorperazine should be used only if prescribed. It may cause side effects in a newborn if the mother takes the medication during pregnancy. This medication can pass into breast milk and may harm a nursing baby. Consult your doctor before breast-feeding.
Can prochlorperazine cause eye movement?
The longer you use prochlorperazine, the more likely you are to develop this disorder, especially if you are a woman or an older adult. Call your doctor at once if you have: uncontrolled muscle movements in your arms and legs, or your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement);
Can cholestasis cause dizziness?
Drowsiness, dizziness, amenorrhea, blurred vision, skin reactions and hypotension may occur. Cholestatic jaundice has occurred. If fever with grippe-like symptoms occurs, appropriate liver studies should be conducted. If tests indicate an abnormality, stop treatment. There have been a few observations of fatty changes in the livers of patients who have died while receiving the drug. No causal relationship has been established.
Does Prochlorperazine interact with other medications?
Prochlorperazine may interact with atropine, lithium, diuretics (water pills), antibiotics, birth control pills or hormone replacement estrogens, blood pressure medications, blood thinners, asthma medications, drugs to treat prostate disorders, incontinence medications, insulin or oral diabetes medications, medication for nausea, vomiting, or motion sickness, medications to treat or prevent malaria, medications used for general anesthesia, medicines used to prevent organ transplant rejection, numbing medicine, stimulants, ADHD medication, ulcer or irritable bowel medications, medicines to treat Parkinson's disease, restless leg syndrome, or pituitary gland tumor. Many other medicines can interact with prochlorperazine. Tell your doctor all medications you use.
For the Consumer
Elderly patients with dementia -related psychosis treated with atypical antipsychotic drugs are at an increased risk of death compared with placebo. Although the causes of death in clinical trials were varied, most deaths appeared to be either cardiovascular (eg, heart failure, sudden death) or infectious (eg, pneumonia) in nature.
For Healthcare Professionals
Applies to prochlorperazine: compounding powder, injectable solution, oral capsule extended release, oral syrup, oral tablet, rectal suppository
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Is compazine a psychotropic drug?
Compazine is also known as a typical antipsychotic drug. In higher doses than those used for the treatment of nausea, it may be used to treat the symptoms of some mental disorders, though this is no longer common. Some of the psychiatric conditions that Compazine may treat include schizophrenia 2 and anxiety.
Can Compazine cause nausea?
Stomach upset can be a side effect of many different medical conditions, including inflammatory bowel disease (IBD) and migraines, Compazine may also be prescribed to patients with cancer who are undergoing chemotherapy or radiation treatment, as nausea and vomiting are potential side effects of anti-cancer drugs.
Does compazine cause muscle pain?
Compazine is also associated with certain side effects. One of the most concerning side effects of Compazine is the development of a muscle disorder known as Tardive dyskinesia, 3 which can occur after long-term use.
What is prochlorperazine used for?
Uses. This medication is used to treat severe nausea and vomiting from certain causes (for example, after surgery or cancer treatment ). Prochlorperazine belongs to a class of drugs known as phenothiazines.This medication is not recommended for use in children younger than 2 years or in children going through surgery.
Where to report side effects?
You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. Precautions.
What drugs cause drowsiness?
Tell your doctor or pharmacist if you are taking other products that cause drowsiness such as opioid pain or cough relievers (such as codeine, hydrocodone ), alcohol, marijuana ( cannabis ), drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine ), or antihistamines (such as cetirizine, diphenhydramine ).
How to reduce lightheadedness and dizziness?
To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.
What are the symptoms of overdose?
Symptoms of overdose may include: mental/mood changes (such as restlessness, agitation), severe drowsiness, seizures, irregular heartbeat. Notes. Do not share this medication with others. Laboratory and/or medical tests may be performed periodically to monitor your progress or check for side effects.
Is compazine safe for dementia?
Compazine Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD. Warnings: There may be a slightly increased risk of serious, possibly fatal side effects (such as heart failure, fast/irregular heartbeat, pneumonia) when this medication is used by older adults with dementia. This medication is not approved for the treatment ...
Does a syringe have side effects?
Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: mental/mood changes (such as agitation, restlessness), unusual/uncontrolled movements (such as fixed upward stare, neck twisting, tongue movements, muscle spasms ), shaking (tremor), difficulty urinating, ...
What are the side effects of prochlorperazine?
Check with your doctor immediately if any of the following side effects occur while taking prochlorperazine: Incidence not known. Agitation. black, tarry stools.
What are the symptoms of overdose on prochlorperazine?
yellow eyes or skin. Get emergency help immediately if any of the following symptoms of overdose occur while taking prochlorperazine: Symptoms of overdose. Change in consciousness. fast, slow, or irregular heartbeat. loss of consciousness. seizures.
What are the extrapyramidal reactions?
Extrapyramidal reactions include acute dystonia, akathisia, parkinsonism, and tardive dyskinesia. These reactions have lasted months to years, especially in elderly patients with brain damage. Grand and petit mal convulsions have occurred in patients with/with a history of EEG abnormalities.
What are the side effects of a syringe?
Side effects not requiring immediate medical attention 1 Blurred vision 2 increased sensitivity of the skin to sunlight 3 irregular menstrual periods 4 itching, rash, redness, or discoloration of the skin 5 jitteriness 6 trouble sleeping
Can tricyclic antidepressants cause cardiovascular side effects?
Cardiovascular side effects may be correlated with higher doses and may occur more frequently in patients with risk factors (e.g., patients with cardiac disease, hypokalemia, receiving tricyclic antidepressants, and/or who are elderly).
Does prochlorperazine need medical attention?
Side effects not requiring immediate medical attention. Some side effects of prochlorperazine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine.
