what are the side effects of ptu

Side Effects of PTU to Report

• Signs of anemia, such as pale skin and fatigue
• Signs of low blood platelets, such as easy bruising or bleeding
• Signs of inflammation of the blood vessels (vasculitis), such as: Weight loss Fatigue Muscle and joint aches Abdominal pain (stomach pain) Difficulty breathing Skin ulcers Fever

Full Answer

What is the most serious adverse effect of propylthiouracil?

• Itching, hives, or a rash.
• Darkening of the skin or jaundice (yellowing of the skin, nails, and whites of the eyes)
• Nausea and vomiting.
• Altered taste and heartburn.
• Headache, drowsiness, or dizziness.
• Joint pain, inflamed nerves, and swelling.
• Swelling of lymph nodes or salivary glands.

Does PTU cause goiters?

PTU is transferred across the placenta. Antithyroid drugs, including PTU, have been shown to cause goiter and hypothyroidism in the developing fetus. There is also a risk for maternal or fetal hepatotoxicity from PTU.

What are the side effects of stopping the pill?

• Start taking folic acid immediately – because you really can get pregnant straight away
• Focus on your sleep hygiene
• Eat well
• Move every day

What are the side effects of propylthiouracil?

What are the side effects of propylthiouracil? SIDE EFFECTS: Stomach upset, nausea, vomiting, mild rash/itching, or headache may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

What are the side effects of PTU?

swelling, nausea, vomiting, heartburn, loss of taste, joint or muscle aches, numbness, and. headache. Less common but serious side effects have occurred with PTU therapy.

When to use PTU?

If it is necessary to use PTU during pregnancy the lowest effective dose should be used. Since methimazole is associated with fetal abnormalities, PTU is used during the first trimester if an antithyroid drug is needed. PTU is excreted in breast milk in small amounts. Consult your doctor before breastfeeding.

What is the side effect of propylthiouracil?

Common side effects of propylthiouracil (PTU) include skin effects (such as rash, itching, hives, abnormal hair loss, and skin pigmentation), swelling, nausea, vomiting, heartburn, loss of taste, joint or muscle aches, ...

Does PTU affect thyroid hormone?

PTU inhibits iodine and peroxidase from their normal interactions with thyroglobulin to form T4 and T3. This action decreases production of thyroid hormone. PTU also interferes with the conversion of T4 to T3, and, since T3 is more potent than T4, this also reduces the activity of thyroid hormones. headache.

Can PTU cause liver failure?

severe liver injury and acute liver failure, which can be fatal. Drug interactions of propylthiouracil (PTU) include oral blood thinners, because PTU may increase their effects. Hyperthyroidism may cause increased elimination of beta-blockers. Once hyperthyroidism is reversed, the excretion of beta-blockers may return to normal ...

Does PTU cause thyroid problems?

Does Propylthiouracil (PTU) cause side effects? Propylthiouracil (PTU) is an anti-thyroid drug used to manage hyperthyroidism which is due to an overactive thyroid gland. Graves' disease is the most common cause of hyperthyroidism. It is an autoimmune disease where an individual makes antibodies to thyroid-stimulating hormone receptors on cells ...

Does propylthiouracil cause a headache?

loss of taste, joint or muscle aches, numbness, and. headache. Serious side effects of propylthiouracil (PTU) include. decreased white blood cells (agranulocytosis) (symptoms include infectious lesions of the throat, the gastrointestinal tract, and skin with an overall feeling of illness and fever ), decreased blood platelets ( thrombocytopenia) ...

What are the side effects of a syringe?

loss of taste. pain or discomfort in the chest, upper stomach, or throat. sensation of spinning. skin rash. sleepiness. Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects.

What are the symptoms of a coma?

agitation. bleeding gums. bleeding under the skin. blood in the urine or stools. bloody or cloudy urine. burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings. coma.

Can medicine cause side effects?

Side Effects. Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur:

What is PTU in medicine?

What is propylthiouracil, and how does it work (mechanism of action)? Propylthiouracil (PTU) is an oral medication that is used to manage hyperthyroidism which is due to an overactive thyroid gland. It is an anti-thyroid drug that has a mechanism of action that is similar to methimazole ( Tapazole ). Graves' disease is the most common cause of ...

What is PTU in medical terms?

Summary. Propylthiouracil (PTU) is a medication prescribed to manage hyperthyroidism and Graves' disease. Side effects, drug interactions, warnings and precautions, and pregnancy safety information should be reviewed prior to taking this medication.

When to use PTU?

If it is necessary to use PTU during pregnancy the lowest effective dose should be used. Since methimazole is associated with fetal abnormalities, PTU is used during the first trimester if an antithyroid drug is needed. PTU is excreted in breast milk in small amounts.

Does theophylline decrease hyperthyroidism?

Similarly, theophylline elimination may decrease when hyperthyroidism is reversed in patients on a stable theophylline dose. A reduced dose of theophylline may be needed in order to avoid toxicity of theophylline.

Can PTU cause headaches?

headache. Less common but serious side effects have occurred with PTU therapy. A decrease of white blood cells in the blood (agranulocytosis) may occur. Symptoms and signs of agranulocytosis include infectious lesions of the throat, the gastrointestinal tract, and skin with an overall feeling of illness and fever.

Can thrombocytopenia cause bleeding?

Since platelets are important for the clotting of blood, thrombocytopenia may lead to excessive bleeding. Severe liver injury and acute liver failure, in some cases fatal, have been associated with PTU. Some adults and pediatric patients required liver transplantation.

Does PTU affect thyroid hormone?

This action decreases production of thyroid hormone. PTU also interferes with the conversion of T4 to T3, and, since T3 is more potent than T4, this also reduces the activity of thyroid hormones. The FDA approved PTU in July 1947.

What are the side effects of propylthiouracil?

headache, dizziness, spinning sensation, joint or muscle pain, decreased sense of taste, or. hair loss. Tell your doctor immediately if you have rare but serious side effects of propylthiouracil including: joint pain, or. changes in the amount of urine.

When to take propylthiouracil?

Propylthiouracil should be used only when prescribed during the first 3 months of pregnancy. It is not recommended for use during the last 6 months of pregnancy. If you are planning pregnancy, become pregnant, or think you may be pregnant, contact your doctor. This medication passes into breast milk.

Does propylthiouracil cause low red blood cells?

Propylthiouracil may rarely cause very serious blood disorders (such as a low number of red cells, white cells, and platelets), especially during the first few months of treatment. Tell your doctor if you develop any of the following symptoms: signs of infection (such as fever, persistent sore throat ),

Can Lupus cause hair loss?

new or worsening symptoms of lupus --joint pain, and a skin rash on your cheeks or arms that worsens in sunlight. hair loss. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Can propylthiouracil cause liver failure?

Propylthiouracil can cause liver damage (especially during the first 6 months of treatment). Liver failure can be fatal or may require a liver transplant. Stop taking propylthiouracil and call your doctor right away if you have signs of liver damage: nausea, vomiting, upper stomach pain; itching;

If experienced, these tend to have a Less Severe expression i

Sorry, we have no data available. Please contact your doctor or pharmacist.

Are you currently using propylthiouracil?

This survey is being conducted by the WebMD marketing sciences department.

What are the side effects of a syringe?

swollen glands; headache, drowsiness, dizziness; swelling in your hands or feet; decreased sense of taste; or. hair loss. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is propylthiouracil used for?

Propylthiouracil is used to treat hyperthyroidism (overactive thyroid), Graves' disease, or toxic goiter (enlarged thyroid). propylthiouracil is sometimes given to control symptoms just before you undergo thyroid surgery or treatment with radioactive iodine.

Can you take propylthiouracil while pregnant?

You should not use propylthiouracil if you are allergic to it. Tell your doctor if you have ever had liver problems. In very rare cases, propylthiouracil has caused liver failure and death in pregnant women during the second or third trimester of pregnancy. Tell your doctor if you are pregnant or plan to become pregnant.

Can you give a child propylthiouracil?

Propylthiouracil may cause liver failure in children, but is sometimes used in children who cannot be treated with other medications. Do not give propylthiouracil to a child without your doctor's advice.

Does propylthiouracil cause hives?

Propylthiouracil side effects. Get emergency medical help if you have signs of an allergic reaction ( hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Can propylthiouracil cause liver failure?

Propylthiouracil can cause liver damage (especially during the first 6 months of treatment). Liver failure can be fatal or may require a liver transplant. Stop taking propylthiouracil and call your doctor right away if you have signs of liver damage: nausea, vomiting, upper stomach pain; itching; fever, tiredness;

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