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what are the side effects of verapamil

by Prof. Willis Rempel Published 3 years ago Updated 2 years ago
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Side Effects
  • Blue lips and fingernails.
  • chest pain.
  • coughing that sometimes produces a pink frothy sputum.
  • difficult, fast, noisy breathing, sometimes with wheezing.
  • dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly.
  • lightheadedness, dizziness, or fainting.
  • shortness of breath.
Apr 1, 2022

Does verapamil cause weight gain?

Can verapamil cause weight gain? Yes, but it is usually water weight. A small number of people (about 2%) who take verapamil may experience edema (swelling of the legs and feet).

Does verapamil cause liver damage?

Verapamil takes a long time to break down in your body, and you may not see an effect right away. Do not take more than prescribed. Taking more than the recommended dosage won’t make it work better for you. Liver enzymes warning: Verapamil can cause liver damage. Your risk is higher if you have a history of liver disease.

Is blurred vision a side effect of verapamil?

Vision blurred is found among people who take Verapamil hydrochloride, especially for people who are female, 60+ old, have been taking the drug for < 1 month. The phase IV clinical study analyzes which people take Verapamil hydrochloride and have Vision blurred. It is created by eHealthMe based on reports of 3,754 people who have side effects when taking Verapamil hydrochloride from the FDA, and is updated regularly.

Can ankle and leg swelling caused by verapamil go away?

swelling in legs and ankles unusual tiredness or weakness Rare. Chills cold sweats feeling of warmth redness of the face, neck, arms and occasionally, upper chest Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine.

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What is a more common side effect associated with verapamil?

Commonly reported side effects of verapamil include: sinus bradycardia. Other side effects include: pulmonary edema, severe hypotension, and second degree atrioventricular block.

Does verapamil cause weight gain?

If you are taking it for high blood pressure, you should continue taking this medication even if you feel fine as high blood pressure often has no symptoms. Can verapamil cause weight gain? Yes, but it is usually water weight.

Can you just stop taking verapamil?

Talk to your doctor if you want to stop taking verapamil. Stopping verapamil may cause your blood pressure to rise and this may increase your risk of a heart attack or stroke. If you're bothered by side effects, talk to your doctor. They may be able to prescribe a different medicine for you.

Why was verapamil discontinued?

Reason for the Shortage Mylan discontinued verapamil extended-release tablets in June 2021. Pfizer has Calan SR tablets on shortage due to manufacturing delay.

How does verapamil make you feel?

Verapamil oral capsule may make you dizzy or drowsy. Don't drive, operate heavy machinery, or do anything that requires mental alertness until you know how it affects you. It may also cause other side effects.

What is a good substitute for verapamil?

Zanaflex.Emgality.Zolmitriptan.Imitrex.Galcanezumab.Indomethacin.

What foods to avoid while taking calcium channel blockers?

Do not eat grapefruit or drink grapefruit juice while you're taking a calcium channel blocker. Avoid alcohol because it can change how calcium channel blockers work and make the side effects worse. Your doctor needs to know about all the medications you're taking, to avoid problems with calcium channel blockers.

Can you take vitamin D with verapamil?

Verapamil (Verelan, Calan SR). Taking high doses of vitamin D with this blood pressure drug can cause hypercalcemia, and might also reduce the effectiveness of verapamil.

Can verapamil cause vision problems?

Low blood pressure (hypotension) may occur while taking this medicine. Check with your doctor right away if you have the following symptoms: blurred vision; confusion; severe dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly; sweating; or unusual tiredness or weakness .

Is verapamil a good blood pressure medicine?

Verapamil is used to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Verapamil belongs to a class of drugs known as calcium channel blockers. It works by relaxing blood vessels so blood can flow more easily.

Should you take verapamil at night?

Adults—At first, 180 milligrams (mg) once daily at bedtime. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor .

Can verapamil cause heart failure?

Verapamil can cause cardiac failure, because it has a potent negative inotropic effect and causes increased capillary filtration pressure by vasodilatation (1).

Do calcium channel blockers make you gain weight?

Side effects from taking calcium channel blockers are usually fairly mild, but may include: Weight gain. Swelling in the lower legs, feet, or ankles.

Which blood pressure medications cause weight gain?

Weight gain can occur as a side effect of some beta blockers. The average weight gain is about 2.6 pounds (1.2 kilograms). Weight gain is more likely with older beta blockers, such as atenolol (Tenormin) and metoprolol (Lopressor, Toprol-XL).

Which one of the following drugs cause weight gain as a side effect?

10 Common Medications That May Cause Weight GainTricyclic Antidepressants. Medications include amitriptyline (Elavil), doxepin (Silenor), nortriptyline (Pamelor). ... Corticosteroids. ... Antihistamines. ... Epilepsy Medications. ... Beta-Blockers. ... SSRIs. ... MAOI. ... Insulin.More items...•

How can I prevent weight gain from medication?

Here are some ways to lose weight gained due to medication use:Switch to a different medication. The first strategy to consider involves changing medications. ... Lower medication dosage. ... Limit portion sizes. ... Exercise. ... Eat more protein. ... Talk to a dietitian. ... Avoid alcohol. ... Get enough sleep.More items...

Before Taking This Medicine

You should not use verapamil if you are allergic to it, or if you have a serious heart condition such as: 1. "sick sinus syndrome" or "AV block" (u...

How Should I Take Verapamil?

Take verapamil exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dos...

What Happens If I Miss A Dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to...

What Happens If I Overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of verapamil can be fatal.

What Should I Avoid While Taking Verapamil?

If you also take disopyramide, avoid taking it within 48 hours before or 24 hours after you take verapamil.Verapamil may impair your thinking or re...

What Other Drugs Will Affect Verapamil?

Many drugs can interact with verapamil. Some drugs can raise or lower your blood levels of verapamil, which may cause side effects or make it less...

What are the side effects of verapamil?

Check with your doctor immediately if any of the following side effects occur while taking verapamil: Less common. Blue lips and fingernails. blurred vision.

Is gingival hyperplasia reversible?

Gingival hyperplasia occurred when this drug was given over a prolonged period of time, and was reversible once the drug was discontinued. [ Ref]

How does verapamil work?

Verapamil is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, verapamil relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload .

Can verapamil be used for heart problems?

Verapamil is used alone or together with other medicines to treat heart rhythm problems, severe chest pain (angina), or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled .

Is verapamil safe for children?

Appropriate studies have not been performed on the relationship of age to the effects of verapamil in the pediatric population. Safety and efficacy have not been established .

What are the symptoms of a severe expression?

If experienced, these tend to have a Severe expression i. slow heartbeat. chronic heart failure. low blood pressure. fluid in the lungs. inflammation of the skin due to an allergy. trouble breathing.

What is the name of the disease that causes blistering and peeling skin?

significantly low blood pressure. overgrowth of gums onto teeth. liver damage. breastmilk production not associated with childbirth or nursing. erythema multiforme, a type of allergic skin reaction. a skin disorder with blistering and peeling skin called Stevens-Johnson syndrome.

Are you currently using verapamil ER?

This survey is being conducted by the WebMD marketing sciences department.

What are the side effects of Verapamil?

Verapamil side effects. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: chest pain, fast or slow heart rate; a light-headed feeling, like you might pass out;

What is verapamil?

Verapamil is a calcium channel blocker. It works by relaxing the muscles of your heart and blood vessels.

How should I use verapamil?

Verapamil injection is given as an infusion into a vein, usually in an emergency situation. A healthcare provider will give you this injection. Your heart rate will be constantly monitored to help determine when your heartbeats have returned to normal.

What is verapamil injection?

Verapamil injection is used to rapidly or temporarily restore normal heartbeats in people with certain heart rhythm disorders.

Can verapamil interact with other medications?

This list is not complete and many other drugs can interact with verapamil. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.

Can you take verapamil if you have high blood pressure?

If you need surgery, tell the surgeon ahead of time that you take verapamil. If you have high blood pressure, keep using this medicine even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.

Can verapamil cause dizziness?

Drinking alcohol with verapamil can cause side effects. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.

What happens if you don't take verapamil?

If you don’t take it at all: If you don’t take verapamil at all, you risk increased blood pressure. This may lead to hospitalization and death.

How long after taking verapamil can you take disopyramide?

Disopyramide. Combining this drug with verapamil may impair your left ventricle. Avoid taking disopyramide 48 hours before or 24 hours after you take verapamil.

Can Verapamil interact with other medications?

Verapamil oral capsule can interact with other medications, vitamin s, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.

Can you take eletriptan with verapamil?

Don’t take eletriptan with verapamil. Verapamil can increase the amount of eletriptan in your body to 3 times as much. This can lead to toxic effects. Don’t take eletriptan for at least 72 hours after you take verapamil.

Does verapamil affect anesthesia?

Verapamil can decrease your heart’s ability to work during general anesthesia. Doses of verapamil and general anesthetics will both need to be adjusted very carefully if they’re used together.

Is Verapamil a generic?

Verapamil oral capsule is a prescription medication that’s available as the brand-name drugs Verelan PM (extended-release) and Verelan (delayed-release). The extended-release oral capsule is also available as a generic drug. Generic drugs usually cost less. In some cases, they may not be available in every strength or form as the brand.

Is Verapamil an oral or oral?

Verapamil is also available as an extended-release oral tablet ( Calan SR) and an immediate-release oral tablet ( Calan ). Both forms of these tablets are also available as generic drugs.

How much verapamil is given daily?

The usual daily dose of extended-release verapamil hydrochloride capsules is 240 mg given by mouth once daily in the morning.

Can broncholaryngeal spasms cause urticaria?

In rare cases of hypersensitive patients, broncho/laryngeal spasm accompanied by itch and urticaria has been reported.

Is Verapamil a slow channel blocker?

Verapamil hydrochloride extended-release is a calcium ion influx inhibitor (slow channel blocker or calcium ion antagonist) indicated for the treatment of hypertension, to lower blood pressure. Verapamil hydrochloride is available in generic form.

Can you breastfeed while taking verapamil?

Verapamil hydrochloride passes into breast milk. Breastfeeding while using verapamil hydrochloride is not recommended.

What are the side effects of Calan?

Common side effects of Calan include: dizziness, weakness, fainting because of a slow heart rate or low blood pressure, swelling of the lower extremities, rash,

How to report side effects of prescription drugs?

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Can Calan be used with Verapamil?

Controlled studies in small numbers of patients suggest that the concomitant use of Calan and oral beta-adrenergic blocking agents may be beneficial in certain patients with chronic stable angina or hypertension, but available information is not sufficient to predict with confidence the effects of concurrent treatment in patients with left ventricular dysfunction or cardiac conduction abnormalities. Concomitant therapy with beta-adrenergic blockers and verapamil may result in additive negative effects on heart rate, atrioventricular conduction and/or cardiac contractility.

Can Verapamil cause liver problems?

Other side effects include: swelling of the lower extremities, rash, headache, nausea, and. constipation. Verapamil also can cause mildly abnormal liver tests that usually return to normal with discontinuation of the medication.

Does verapamil cause neurotoxicity?

Increased sensitivity to the effects of lithium ( neurotoxicity) has been reported during concomitant verapamil-lithium therapy; lithium levels have been observed sometimes to increase, sometimes to decrease, and sometimes to be unchanged. Patients receiving both drugs must be monitored carefully.

Does verapamil affect AV?

The electrophysiologic effects of quinidine and verapamil on AV conduction were studied in 8 patients. Verapamil significantly counteracted the effects of quinidine on AV conduction. There has been a report of increased quinidine levels during verapamil therapy.

What happens if you don't take verapamil?

If you don’t take it at all: If you don’t take verapamil at all, you risk increased blood pressure. This may lead to hospitalization and death.

How long after taking verapamil can you take disopyramide?

Disopyramide. Combining this drug with verapamil may impair your left ventricle. Avoid taking disopyramide 48 hours before or 24 hours after you take verapamil.

Can you take Verapamil and Dofetilide together?

This combination may also cause a serious heart condition called torsade de pointes. Don’t take these medications together.

Can verapamil interact with other medications?

Verapamil may interact with other medications. Verapamil oral capsule can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.

Does verapamil lower blood pressure?

Verapamil is a calcium channel blocker. It works to relax your blood vessels and improve blood flow, which helps to lower blood pressure. This medication affects the amount of calcium found in your heart and muscle cells. This relaxes your blood vessels, which can reduce the amount of work your heart has to do.

Is Verapamil a generic?

Verapamil is also available as both generic and brand-name immediate- release oral tablets (Cal an) and extended-release oral tablets (Calan SR). Verapamil relaxes your blood vessels, which can reduce the amount of work your heart has to do. It’s used to treat high blood pressure.

Is Verapamil an oral or oral?

Verapamil is also available as an extended-release oral tablet ( Calan SR) and an immediate-release oral tablet ( Calan ). Both forms of these tablets are also available as generic drugs.

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in Summary

For The Consumer

Common side effects

  • Constipation
  • Dizziness
  • Peripheral edema
  • Headache disorder
  • Infection

Common side effects

  • Constipation
  • Dizziness
  • Peripheral edema
  • Headache disorder
  • Infection
  • Flu-like symptoms
  • Pharyngitis
  • Sinusitis
  • Bradycardia
  • Chronic heart failure
  • Pulmonary edema
  • Dyspnea
  • Allergic dermatitis
  • Fatigue
  • Skin rash
  • Nausea
  • Hypotension
  • Edema
  • Rhinitis


If any of these effects persist or worsen, tell your doctor or pharmacist promptly

  • Dizziness
  • Slow heartbeat
  • Constipation
  • Stomach upset
  • Nausea


If any of these effects persist or worsen, tell your doctor or pharmacist promptly

  • Dizziness
  • Slow heartbeat
  • Constipation
  • Stomach upset
  • Nausea
  • Headache
  • Tiredness

Tell your doctor right away if you have any serious side effects, including

  • Severe dizziness
  • Fainting
  • New or worsening symptoms of heart failure
  • Very slow heartbeat

This drug may rarely cause serious liver disease. Get medical help right away if you have any symptoms of liver damage, such as

  • Nausea/vomiting that doesn't stop
  • Loss of appetite
  • Stomach/abdominal pain
  • Yellowing eyes/skin
  • Dark urine

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including

  • Rash
  • Itching/swelling
  • Severe dizziness
  • Trouble breathing

Other things to note

  • To lower your risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.

For Healthcare Professionals

Further Information

1.Verapamil (Oral Route) Side Effects - Mayo Clinic

Url:https://www.mayoclinic.org/drugs-supplements/verapamil-oral-route/side-effects/drg-20071728

31 hours ago  · Verapamil side effects Get emergency medical help if you have signs of an allergic reaction: hives ; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have:

2.Verapamil Side Effects: Common, Severe, Long Term

Url:https://www.drugs.com/sfx/verapamil-side-effects.html

33 hours ago  · Most common side effects. The most common side effects that occur with verapamil include: constipation; face flushing; headache; nausea and vomiting; sexual problems, such as erectile dysfunction ...

3.Verapamil (Oral Route) Side Effects - Mayo Clinic

Url:https://www.mayoclinic.org/drugs-supplements/verapamil-oral-route/side-effects/DRG-20071728?p=1

17 hours ago  · Common side effects of verapamil hydrochloride include: constipation, headache, dizziness, fatigue, indigestion, skin rash, swelling of the ankles, sleep problems, and muscle pain

4.Common and Rare Side Effects for verapamil oral - WebMD

Url:https://www.webmd.com/drugs/2/drug-7086-225/verapamil-oral/verapamil-extended-release-capsule-oral/details/list-sideeffects

31 hours ago Common side effects of Verapamil are: dizziness, weakness or; fainting because of a slow heart rate or low blood pressure. Other side effects include: swelling of the lower extremities, rash, headache, nausea, and; constipation. Verapamil also can cause mildly abnormal liver tests that usually return to normal with discontinuation of the medication. Verapamil may reduce heart rate.

5.Verapamil: Uses, Dosage & Side Effects - Drugs.com

Url:https://www.drugs.com/verapamil.html

23 hours ago low blood pressure. significantly low blood pressure. liver problems. decreased kidney function. blood circulation failure due to serious heart condition. chronic idiopathic constipation. Lown ...

6.Verapamil | Side Effects, Dosage, Uses & More - Healthline

Url:https://www.healthline.com/health/drugs/verapamil-oral-capsule

24 hours ago  · Most common side effects. The most common side effects that occur with verapamil include: constipation; face flushing; headache; nausea and vomiting; sexual problems, such as erectile dysfunction ...

7.Side Effects of Verapamil Hydrochloride (Verapamil

Url:https://www.rxlist.com/verapamil-hydrochloride-side-effects-drug-center.htm

17 hours ago

8.Side Effects of Calan (verapamil): Interactions & Warnings

Url:https://www.medicinenet.com/side_effects_of_calan_verapamil/side-effects.htm

32 hours ago

9.Common and Rare Side Effects for verapamil oral - WebMD

Url:https://www.webmd.com/drugs/2/drug-7086-1010/verapamil-oral/verapamil-oral/details/list-contraindications

15 hours ago

10.Verapamil: Side effects, dosage, uses, and more

Url:https://www.medicalnewstoday.com/articles/verapamil-oral-capsule

35 hours ago

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