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what can cause spina bifida

by Dale Doyle Published 2 years ago Updated 1 year ago
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Doctors aren't certain what causes spina bifida. It's thought to result from a combination of genetic, nutritional and environmental risk factors, such as a family history of neural tube defects and folate (vitamin B-9) deficiency.Jan 8, 2022

Causes

What are long term effects of spina bifida? A: Long term problems associated with Spina Bifida include: Sensation – This means that there may be areas of numbness in the legs. Bowel problems – Most Spina Bifida children have some problem controlling their bowel movements. Intellect and education – Around 75% of children with Spina Bifida have some learning difficulties.

Symptoms

When people talk about spina bifida, most often they are referring to myelomeningocele. Myelomeningocele is the most serious type of spina bifida. With this condition, a sac of fluid comes through an opening in the baby’s back. Part of the spinal cord and nerves are in this sac and are damaged.

Prevention

The signs and symptoms of a possible neurological complication like a tethered spinal cord include:

  • Pain in the back or legs
  • Weakness in the legs
  • Numbness or other changes in feeling in the legs or back
  • Deformed legs, feet and back
  • Change in bladder or bowel function

Complications

Spina bifida is a condition that affects the spine and is usually apparent at birth. It is a type of neural tube defect (NTD). Spina bifida can happen anywhere along the spine if the neural tube does not close all the way. When the neural tube doesn’t close all the way, the backbone that protects the spinal cord doesn’t form and close as it should.

What are the long term effects of spina bifida?

What is the most serious form of spina bifida?

How does spina bifida affect the nervous system?

What part of the body does spina bifida affect?

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Who is most at risk for spina bifida?

obesity – women who are obese (have a body mass index of 30 or more) are more likely to have a child with spina bifida than those of average weight. diabetes – women with diabetes may have an increased risk of having a child with spina bifida.

How does spina bifida occur in pregnancy?

About spina bifida A baby's spine and brain begin to develop from the neural tube of the embryo during the first month of pregnancy. Spina bifida occurs when the neural tube has a defect and fails to close completely, leaving a gap in the baby's spine.

Can a baby survive with spina bifida?

About 1,500 to 2,000 babies of the 4 million born in the U.S. every year have spina bifida. Thanks to advances in medicine, 90% of babies who have this defect live to be adults, and most go on to lead full lives.

What week of pregnancy does spina bifida occur?

Spina bifida and anencephaly are birth defects that occur in the first four weeks of pregnancy, before most women know that they are pregnant. Because about half of all pregnancies are unplanned, it is important to include 400 micrograms of folic acid in every childbearing age woman=s diet.

Can you tell if a fetus has spina bifida?

Ultrasound. Fetal ultrasound is the most accurate method to diagnose spina bifida in your baby before delivery. Ultrasound can be performed during the first trimester (11 to 14 weeks) and second trimester (18 to 22 weeks). Spina bifida can be accurately diagnosed during the second trimester ultrasound scan.

How is spina bifida prevented?

Folic Acid Supplement Because spina bifida occurs early in pregnancy, doctors recommend that women who are planning to have a baby start taking 400 micrograms of folic acid every day for at least three months before trying to become pregnant. Women should continue to take folic acid daily throughout pregnancy.

Can a child with spina bifida ever walk?

People affected by spina bifida get around in different ways. These include walking without any aids or assistance; walking with braces, crutches or walkers; and using wheelchairs. People with spina bifida higher on the spine (near the head) might have paralyzed legs and use wheelchairs.

Can stress cause spina bifida?

Increased stress was associated with an increased risk of spina bifida and anencephaly particularly among women who did not take folic acid supplements.

What are the chances of spina bifida in pregnancy?

In both situations, the chance for spina bifida is estimated to be about 3% for each pregnancy. Research shows that women who have had a previous pregnancy with spina bifida or women who themselves have spina bifida can significantly reduce their risk of in any future pregnancy by taking a folic acid supplement.

Can folic acid prevent spina bifida?

Folic acid can reduce certain birth defects of the brain and spinal cord by more than 70 percent. These birth defects are called neural tube defects (NTDs). NTDs happen when the spinal cord fails to close properly. The most common neural tube defect is spina bifida.

How is spina bifida inherited?

Inheritance. Most cases of spina bifida are sporadic, which means they occur in people with no history of the disorder in their family. A small percentage of cases have been reported to run in families; however, the condition does not have a clear pattern of inheritance.

What causes neural tube defects in the fetus?

Neural tube defects are considered a complex disorder because they are caused by a combination of multiple genes and multiple environmental factors. Known environmental factors include folic acid, maternal insulin dependent diabetes, and maternal use of certain anticonvulsant (antiseizure) medications.

What is Spina Bifida?

Treatments. Causes. Living with Spina Bifida. Spina bifida is a condition that affects the spine and is usually apparent at birth. It is a type of neural tube defect (NTD). Spina bifida can happen anywhere along the spine if the neural tube does not close all the way. When the neural tube doesn’t close all the way, ...

Why is Spina Bifida not diagnosed?

Sometimes spina bifida is not diagnosed until after the baby is born because the mother did not receive prenatal care or an ultrasound did not show clear pictures of the affected part of the spine.

What are the three types of spina bifida?

Types of Spina Bifida. The three most common types of spina bifida are: Myelomeningocele (sounds like: my-low-ma-nin-jo-seal; hear how “myelomeningocele” sounds. external icon. ) When people talk about spina bifida, most often they are referring to myelomeningocele.

What is the condition that causes a person to not be able to move their legs?

This type of spina bifida causes moderate to severe disabilities, such as problems affecting how the person goes to the bathroom, loss of feeling in the person’s legs or feet, and not being able to move the legs. Another type of spina bifida is meningocele.

Do all people with spina bifida need the same treatment?

Not all people born with spina bifida have the same needs, so treatment will be different for each person. Some people have problems that are more serious than others. People with myelomeningocele and meningocele will need more treatments than people with spina bifida occulta.

Is there a small gap in the spine?

It is sometimes called “hidden” spina bifida. With it, there is a small gap in the spine, but no opening or sac on the back. The spinal cord and the nerves usually are normal. Many times, spina bifida occulta is not discovered until late childhood or adulthood.

Is the spinal cord in the sac?

But, the spinal cord is not in this sac. There is usually little or no nerve damage. This type of spina bifida can cause minor disabilities. Spina Bifida Occulta (sounds like: o-cult-tuh; hear how “occulta” sounds. external icon. ) Spina bifida occulta is the mildest type of spina bifida.

What are the risk factors for spina bifida?

Other risk factors for spina bifida include: 1 obesity – women who are obese (have a body mass index of 30 or more) are more likely to have a child with spina bifida than those of average weight 2 diabetes – women with diabetes may have an increased risk of having a child with spina bifida

Which is more likely to have a child with spina bifida?

obesity – women who are obese (have a body mass index of 30 or more) are more likely to have a child with spina bifida than those of average weight. diabetes – women with diabetes may have an increased risk of having a child with spina bifida. Previous. :

What test can be done to confirm if a baby has spina bifida?

If your baby is found to have spina bifida and it's thought they may also have one of these syndromes, you'll be offered a diagnostic test, such as amniocentesis or chorionic villus sampling. These tests can confirm if your baby has one of these genetic conditions.

Can spina bifida cause a baby to have a spina bifid?

It's not known what causes spina bifida but a number of things can increase the risk of a baby developing the condition.

What is spina bifida caused by?

Listen. Spina bifida is a complex condition that in most cases, is likely caused by the interaction of multiple genetic and environmental factors (called multifactorial inheritance). Some of these factors have been identified, but many remain unknown. Changes in any of many genes may influence the risk of spina bifida.

What is spinal bifida?

Spina bifida is a type of neural tube defect in which the neural tube (the structure in an embryo that becomes the brain and spinal cord) does not completely close during development in the womb. This may result in part of the spinal cord sticking out through an opening in the spine, leading to permanent nerve damage.

What is the term for a baby with spina bifida?

Babies born with spina bifida often have a fluid-filled sac, covered by skin, on their back. This is called a meningocele. If the sac contains part of the spinal cord and its protective covering, it is known as a myelomeningocele.

How do you know if you have spina bifida?

Possible symptoms include include a loss of feeling below the level of the opening, weakness or paralysis of the feet or legs, problems with bladder and bowel control, hydrocephalus, and learning problems. [1] ...

When did doctors start trying to close spina bifida?

In 1994 , doctors began trying out various methods for closing spina bifida defects while the baby is still in the mother's womb. Since that time, many improvements have been made in the procedure. It is still not know, however, whether it is better to operate on a baby with spina bifida before or after it is born.

Is Spina Bifida occulta treatable?

Long-term physical, occupational, and/or speech therapy may be needed. In some cases, the condition is life-threatening and is not treatable. [2] There is also a milder form of the condition called spina bifida occulta in which the nerves develop normally and health problems rarely occur. [1] Last updated: 8/8/2017.

Does folic acid cause spina bifida?

Changes in any of many genes may influence the risk of spina bifida. The best-studied of these genes is MTHFR, which provides instructions for making the B-vitamin folate (also called folic acid, or vitamin B9). [1] Maternal folate deficiency increases the risk to have a baby with spina bifida, and women who take folic acid supplements before and during early pregnancy are much less likely to have a baby with spina bifida. [1]

What is spina bifida?

Spina bifida is a birth defect in which an area of the spinal column doesn’t form properly, leaving a section of the spinal cord and spinal nerves exposed through an opening in the back.

What is the most common form of spina bifida?

Myelomeningocele. The most common and serious form of spina bifida is called myelomeningocele (my•e•lo•me•nin•go•cele) (MMC), in which part of the spinal cord and surrounding nerves push through the open bones (vertebrae) in the spine and protrude from the fetus’ back. In myelomeningocele, spinal cord and nerves protrude from the back in a sac ...

How many children die from Spina Bifida?

Spina bifida prognosis. Fourteen percent of children born with myelomeningocele die before the age of 5, primarily due to hindbrain herniation complications. Many patients require shunts (85 percent), and 45 percent of shunts develop complications within one year.

How long does it take for spina bifida surgery to be performed?

If your unborn baby has been diagnosed with myelomeningocele and you are a candidate for prenatal spina bifida treatment at Children’s Hospital of Philadelphia, the surgery is performed between 23 weeks and 25 weeks 6 days gestation . Learn more about fetal surgery for spina bifida ».

How early can you detect spina bifida?

Evaluation and diagnosis of spina bifida. As with other birth defects, most myelomeningoceles are discovered by routine ultrasound evaluation between 16 and 18 weeks into the pregnancy. Fetal ultrasound depicting myelomeningocele Sonographic features suggestive of myelomeningocele include a cystic mass anywhere on the spine.

What is the hindbrain herniation?

Hindbrain herniation is a common finding for babies with spina bifida in which the lower, back part of the brain (the hindbrain) starts to come down (herniate) into the top of the spinal canal. Pictured here: Hindbrain in normal position.

How many babies are born with Spina Bifida each year?

Spina bifida occurs in 1 per 2,000 live births in the United States and is the most common central nervous system birth defect. Around 1,500 babies are born with spina bifida in the U.S. each year. Find some more fast facts about spina bifida.

What is Spina Bifida?

Spina bifida is what is known as a neural tube defect. It occurs during development prior to birth. It’s when the spinal cord, brain, or meninges (their protective covering) does not completely develop. It can be anywhere along the spine and usually can be seen in an opening in the baby’s back at birth. It may also appear as a sack of fluid that has grown outside the body on the spine. This sack may or may not include the spinal cord inside.

How to prevent spina bifida?

Follow these preventive steps: Take a folic acid supplement as prescribed by your doctor. Include leafy green vegetables, nuts, beans, and other foods that contain folic acid in your diet.

How to tell if you have myelomeningocele spina bifida?

Symptoms of myelomeningocele spina bifida include: open spinal canal over some vertebrae, usually in the middle or lower part of the back. membranes and spinal cord pushed outside the back in an exposed or skin-covered sack. weak or paralyzed leg muscles. seizures.

What are the symptoms of Spina Bifida Occulta?

Symptoms of spina bifida occulta include: a gap in between vertebrae. no visible opening outside. no fluid-filled sack outside the body. small birthmark or dimple on the back. small group or cluster of hair on the back. an area of extra fat on the back.

What are the physical disabilities of myelomeningocele?

These disabilities may include: incontinence. difficulty going to the bathroom. inability to move or feel their legs or feet.

How many types of spina bifida are there?

There are three types of spina bifida: myelomeningocele, meningocele, and spina bifida occulta.

Can a child with spina bifida go to college?

Coping mechanisms, medications, therapies, and any walking aids are normally in place. Many children with spina bifida grow up to attend college and have careers. Some also live independently. However, ongoing medical issues can develop throughout the life of a person with spina bifida.

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Types of Spina Bifida

Diagnosis

Causes

  • SBO results from neural tube defect. Neural tube is the structure in an embryo that develops into the brain, spinal cord, and their coverings
  • Neural tube defect is considered to be due to:
  • Genetic defects
  • Folic acid deficiency
  • The risk factors include:
  • Family history of neural tube defects
  • Diabetes
  • Obesity
  • Some medications taken during pregnancy, for example, antiseizure drugs
  • Girls are at increased risk
  • Race: Caucasian and Hispanics are more affected

Symptoms
If you are experiencing new, severe, or persistent symptoms, contact a health care provider.

Symptoms may vary from person to person and may have no significance on incidence or severity. Few symptoms may include:

  • SBO involves only the vertebrae and not the spinal nerves
  • Most people with SBO do not exhibit any signs or symptoms

Few indications may be noted at the site of defect in the spine include:

  • Abnormal tuft of hair
  • Collection of fat
  • Small dimple or birthmark

Some of the symptoms noted include:

  • Foot deformity
  • Back pain
  • Weakness or numbness in hands or legs
  • Pain in the back of the legs

Prevention

Get enough folic acid during pregnancy either through diet or folic acid supplements.

Complications

Complications may include:

  • Tethered cord syndrome or attachment of the spinal cord to the spinal column, limiting its movement
  • Neurological problems due to tethered cord syndrome, including back pain
  • Loss of bowel or bladder control
  • Scoliosis or curving of the spine

Treatments

Causes and Prevention

Living with Spina Bifida

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The three most common types of spina bifida are: Myelomeningocele (sounds like: my-low-ma-nin-jo-seal; hear how “myelomeningocele” soundsexternal icon) When people talk about spina bifida, most often they are referring to myelomeningocele. Myelomeningocele is the most serious type of spina bifida. With this condition, a …
See more on cdc.gov

1.Spina bifida - Symptoms and causes - Mayo Clinic

Url:https://www.mayoclinic.org/diseases-conditions/spina-bifida/symptoms-causes/syc-20377860

15 hours ago  · Spina bifida is a birth defect that mainly affects the spine. Normally in the first month of pregnancy, a special set of cells forms the “neural tube.”. The top of the tube …

2.What causes spina bifida? | NICHD - Eunice Kennedy …

Url:https://www.nichd.nih.gov/health/topics/spinabifida/conditioninfo/causes

12 hours ago The cause in most cases is multifactorial, which means that both genetic and environmental factors interact to cause Spina bifida. Some cases may be due to the inheritance of specific …

3.Spina bifida - Causes - NHS

Url:https://www.nhs.uk/conditions/spina-bifida/causes/

6 hours ago Research suggests that the cause could relate to several genetic, nutritional and environmental factors, including: A lack of folic acid (vitamin B9) during pregnancy. A history of the condition …

4.Spina Bifida Fact Sheet | National Institute of …

Url:https://www.ninds.nih.gov/spina-bifida-fact-sheet

27 hours ago When the spine and spinal cord do not develop properly, it becomes the cause of spina bifida, a birth anomaly that is a particular form of a neural tube defect. The neural tube is a structure in …

5.Spina bifida - About the Disease - Genetic and Rare …

Url:https://rarediseases.info.nih.gov/diseases/7673/spina-bifida/

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6.Spina Bifida Causes, Symptoms and Treatment

Url:https://www.chop.edu/conditions-diseases/spina-bifida

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7.Spina Bifida: Types, Treatments, and Symptoms - Healthline

Url:https://www.healthline.com/health/spina-bifida

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8.Spina Bifida Occulta (Hidden Spina Bifida) - Cleveland Clinic

Url:https://my.clevelandclinic.org/health/diseases/22825-spina-bifida-occulta

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