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what causes depolarization of skeletal muscle

by Marianne Ratke Published 2 years ago Updated 2 years ago
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Different types of stimuli that can begin the process of depolarization are as follows:

  • Light stimulus as in rods and cons
  • Pain stimulus in skin
  • Touch, pressure or vibration stimulus
  • Heat or cold stimulus

Activation of the nAChR leads to an influx of cations (sodium and calcium) that causes depolarization of the muscle cell membrane. This depolarization in turn activates a high density of voltage-gated sodium channels on the muscle membrane, eliciting an action potential.

Full Answer

How do skeletal muscle cells respond to depolarization?

In cardiac muscles, depolarization causes contraction of cardiac muscles. The skeletal muscles also respond to depolarization by contraction. Nicotinic agonists can cause prolonged depolarization state of the cells. They prevent the cells from undergoing repolarization. As a result, cells do not respond to the new stimuli.

Where does the influx of sodium depolarize the muscle cell?

The influx of sodium depolarizes the muscle cell in the vicinity of the motor endplate. Depolarization means the difference in charge between the inside and outside of the muscle is reduced.

What happens to sodium levels during depolarization?

A different type of sodium channel, which is activated in response to depolarization, lets more sodium in and the wave of excitation spreads throughout the muscle cell. This leads to the release of calcium ions from storage sites inside the muscle cell.

What is the role of depolarization in cardiac muscle contraction?

depolarization helps to regulate the structural rigidity and vascular tone. In cardiac muscles, depolarization causes contraction

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What is depolarization of a muscle?

In muscle: Release of acetylcholine from the nerve terminal. The channels are opened by depolarization (an increase in membrane potential) of the nerve terminal membrane and selectively allow the passage of calcium ions. In muscle: The frequency of contraction.

What causes depolarization to occur?

Depolarization is caused when positively charged sodium ions rush into a neuron with the opening of voltage-gated sodium channels. Repolarization is caused by the closing of sodium ion channels and the opening of potassium ion channels.

What causes depolarization in smooth muscle?

This depolarization is induced either by ionotropic receptors (vas deferens) or a membrane oscillator (bladder and uterus). The membrane oscillator, which resides in the plasma membrane, generates the periodic pacemaker depolarizations responsible for the action potentials that drive contraction.

What promotes depolarization?

The opening of channels that let positive ions flow into the cell can cause depolarization.

Where does depolarization happen in the muscle tissue?

sarcolemmal membraneCell membrane depolarization is stimulated by nerve impulses arriving at the neuromuscular junction. Following the generation of a sufficient motor endplate potential, depolarization occurs along the sarcolemmal membrane.

Which of the following events will lead to depolarization?

Answer and Explanation: The event that will lead to depolarization is the rapid influx of sodium (Na+) ions from the extracellular fluid (ECF) to the intracellular fluid (ICF). These ions carry a positive charge, and will depolarize the membrane of an excitable cell to +30 mV.

Does depolarization mean contraction?

Answer and Explanation: Depolarization does not mean contraction. Depolarization is a process where a cell's membrane potential becomes more positive. In certain types of contractile tissue, such as muscle or heart tissue, this can result in contraction.

Is depolarization contraction or relaxation?

Depolarization of the heart leads to the contraction of the heart muscles and therefore an EKG is an indirect indicator of heart muscle contraction. The cells of the heart will depolarize without an outside stimulus. This property of cardiac muscle tissue is called automaticity, or autorhythmicity.

What depolarization mean?

movement of a cell's membrane potential to a more positive value (i.e. movement closer to zero from resting membrane potential). When a neuron is depolarized, it is more likely to fire an action potential.

Does potassium cause depolarization?

Elevated potassium Increased extracellular potassium levels result in depolarization of the membrane potentials of cells due to the increase in the equilibrium potential of potassium. This depolarization opens some voltage-gated sodium channels, but also increases the inactivation at the same time.

What happens when depolarization occurs?

During the depolarization phase, the gated sodium ion channels on the neuron's membrane suddenly open and allow sodium ions (Na+) present outside the membrane to rush into the cell. As the sodium ions quickly enter the cell, the internal charge of the nerve changes from -70 mV to -55 mV.

How does a stimulus cause depolarization?

A stimulus first causes sodium channels to open. Because there are many more sodium ions on the outside, and the inside of the neuron is negative relative to the outside, sodium ions rush into the neuron. Remember, sodium has a positive charge, so the neuron becomes more positive and becomes depolarized.

Does potassium cause depolarization?

Elevated potassium Increased extracellular potassium levels result in depolarization of the membrane potentials of cells due to the increase in the equilibrium potential of potassium. This depolarization opens some voltage-gated sodium channels, but also increases the inactivation at the same time.

How does a neuron cell membrane become depolarized?

Neuronal depolarization depends on the opening of ion channels in the neuronal membrane and the subsequent influx of sodium ions (Na+) and efflux of potassium ions (K+). The response of a neuron to ion channel receptor activation by either the natural ligand/neurotransmitter or a drug is rapid and brief.

What happens when depolarization occurs?

During the depolarization phase, the gated sodium ion channels on the neuron's membrane suddenly open and allow sodium ions (Na+) present outside the membrane to rush into the cell. As the sodium ions quickly enter the cell, the internal charge of the nerve changes from -70 mV to -55 mV.

What is depolarization in the nervous system?

Depolarization in a nerve cell occurs when the cell undergoes an electrical shift. Most cells are negatively charged relative to their surroundings. This negative internal charge of the cell shifts to a positive through depolarization, which occurs for only a brief period of time.

1.Depolarization | Physiology, Process, Summary, Facts

Url:https://human-memory.net/depolarization/

22 hours ago Skeletal Muscles The opening of sodium channels causes depolarization of the skeletal muscle. The action potential from the motor neuron also travels through the T-tubules. It causes the …

2.Physiology, Skeletal Muscle - StatPearls - NCBI Bookshelf

Url:https://www.ncbi.nlm.nih.gov/books/NBK537139/

29 hours ago In skeletal muscle, depolarization is mediated by impulses from motor nerves, which are under the control of the somatic nervous system. In smooth muscle, although it is innervated by the visceral (autonomous) nervous system (and therefore not under voluntary control), neural input is not always of the same central importance as in skeletal muscle.

3.Skeletal Muscles Lecture 2 Flashcards | Quizlet

Url:https://quizlet.com/358249288/skeletal-muscles-lecture-2-flash-cards/

2 hours ago Depolarization of skeletal muscles also occurs via the influx of sodium ions. The depolarization of smooth muscles is due to calcium channels. Cardiac muscles undergo depolarization due to sodium as well as calcium ions influx.

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