
What are the risk factors for vulvar cancer?
Increasing age. The risk of vulvar cancer increases with age, though it can occur at any age. The average age at diagnosis is 65. Being exposed to human papillomavirus (HPV). HPV is a sexually transmitted infection that increases the risk of several cancers, including vulvar cancer and cervical cancer.
What is severe vulvar dysplasia?
Severe vulvar dysplasia is considered a non-invasive vulvar cancer, in which intensive cell proliferation and nuclear cell atypia do not extend to the basement membrane and stroma. The main cause is a local, long-term persistent HPV infection (especially oncogenic types 16 and 18).
What is vulvar dysplasia (Vin)?
When you have abnormal skin changes in your vulva but it’s not cancer, it’s called vulvar dysplasia. If your case is high grade, it’s called vulvar intraepitheleial neoplasia (VIN).
What causes vulvar melanoma?
Vulvar melanoma. This cancer begins in the pigment-producing cells found in the skin of the vulva. Although the exact cause of vulvar cancer isn't known, certain factors appear to increase your risk of the disease, including: Increasing age.

What causes vulvar cancer?
Although the exact cause of vulvar cancer isn't known, certain factors appear to increase your risk of the disease, including: 1 Increasing age. The risk of vulvar cancer increases with age, though it can occur at any age. The average age at diagnosis is 65. 2 Being exposed to human papillomavirus (HPV). HPV is a sexually transmitted infection that increases the risk of several cancers, including vulvar cancer and cervical cancer. Many young, sexually active people are exposed to HPV, but for most the infection goes away on its own. For some, the infection causes cell changes and increases the risk of cancer in the future. 3 Smoking. Smoking increases the risk of vulvar cancer. 4 Having a weakened immune system. People who take medications to suppress the immune system, such as those who've undergone organ transplant, and those with conditions that weaken the immune system, such as human immunodeficiency virus (HIV), have an increased risk of vulvar cancer. 5 Having a history of precancerous conditions of the vulva. Vulvar intraepithelial neoplasia is a precancerous condition that increases the risk of vulvar cancer. Most instances of vulvar intraepithelial neoplasia will never develop into cancer, but a small number do go on to become invasive vulvar cancer. For this reason, your doctor may recommend treatment to remove the area of abnormal cells and periodic follow-up checks. 6 Having a skin condition involving the vulva. Lichen sclerosus, which causes the vulvar skin to become thin and itchy, increases the risk of vulvar cancer.
Why is my vulva thin?
Having a skin condition involving the vulva. Lichen sclerosus, which causes the vulvar skin to become thin and itchy, increases the risk of vulvar cancer.
How to reduce the risk of vulvar cancer?
To reduce your risk of vulvar cancer, reduce your risk of the sexually transmitted infection HPV: Use a condom every time you have sex. Condoms may reduce your risk of contracting HPV but can't fully protect against it. Get the HPV vaccine.
What is the average age for vulvar cancer?
The risk of vulvar cancer increases with age, though it can occur at any age. The average age at diagnosis is 65. Being exposed to human papillomavirus (HPV). HPV is a sexually transmitted infection that increases the risk of several cancers, including vulvar cancer and cervical cancer.
What type of cancer is vulvar?
The most common types of vulvar cancer include: Vulvar squamous cell carcinoma. This cancer begins in the thin, flat cells that line the surface of the vulva. Most vulvar cancers are squamous cell carcinomas. Vulvar melanoma. This cancer begins in the pigment-producing cells found in the skin of the vulva.
How is vulvar cancer treated?
Vulvar cancer treatment usually involves surgery to remove the cancer and a small amount of surrounding healthy tissue. Sometimes vulvar cancer surgery requires removing the entire vulva. The earlier vulvar cancer is diagnosed, the less likely an extensive surgery is needed for treatment.
Can vulva cancer develop?
Most instances of vulvar intraepithelial neoplasia will never develop into cancer, but a small number do go on to become invasive vulvar cancer.
What is vulvar cancer?
Vulvar Cancer. Vulvar cancer is a rare cancer of a woman’s vulva. There are about 6,000 new cases of vulvar cancer in the U.S. each year. About half the cases are caused by human papillomavirus and half are caused by lichen sclerosus. Symptoms include changes in vulvar skin color and lumps or open sores.
What are the symptoms of vulvar?
Symptoms include changes in vulvar skin color and lumps or open sores. Treatments include surgery, radiation and chemotherapy. Appointments & Access. Contact Us. Overview. Symptoms and Causes. Diagnosis and Tests. Management and Treatment. Prevention.
What age is vulvar cancer most commonly diagnosed?
Having a medical condition that weakens your immune system. Being a smoker. Vulvar cancer is most frequently diagnosed in women aged 65 to 74. However, vulvar cancer is becoming more common in younger women.
How long do women live with vulvar cancer?
According to the National Cancer Institute, the relative five-year survival rate for women with vulvar cancer is 71%. Higher five-year survival rates are seen in earlier stage disease (over 90% for stage I) compared with late stage disease (15% for stage IV). A note from Cleveland Clinic.
What does it mean when your vulva is red?
Changes in the vulvar skin color (more red or white/pale than normal). Growths or lumps in the vulva that look like a wart or ulcer; or a rash or other sore that doesn’t heal. Itching or burning in the vulvar area that does not go away. Bleeding in the vulvar area not related to menstruation (periods).
Where does vulvar cancer occur?
Vulvar cancer most often develops on the inner or outer vaginal lips, but can arise in any location of the vulva. Vulvar cancer usually develops slowly over several years. Precancerous lesions usually develop first and are discovered as abnormal cell growth in the outer most layer of skin.
Where is the Mons pubis?
Mons pubis (the rounded area in front of the pubic bones that becomes covered with hair at puberty). Opening of the urethra (where pee exits your body). Perineum (the area between the vagina and the anus). Vulvar cancer most often develops on the inner or outer vaginal lips, but can arise in any location of the vulva.
What causes vulvar skin to become thin and itchy?
Lichen sclerosus. This disorder, also called lichen sclerosus et atrophicus (LSA), causes the vulvar skin to become very thin and itchy. The risk of vulvar cancer appears to be slightly increased by LSA, with about 4% of women having LSA later developing vulvar cancer.
What are the risk factors for Vulvar cancer?
Risk Factors for Vulvar Cancer. A risk factor is anything that changes a person's chance of getting a disease such as cancer. Different cancers have different risk factors. For example, exposing skin to strong sunlight is a risk factor for skin cancer. Smoking is a risk factor for many cancers.
What causes a VIN to be warty?
Usual-type VIN occurs in younger women and is caused by HPV infection. When usual-type VIN changes into invasive squamous cell cancer, it becomes the basaloid or warty subtypes.
What is the VIN of a vulvar?
Intraepithelial means that the abnormal cells are only found in the surface layer of the vulvar skin (epithelium). VIN is typed by how the lesions and cells look: usual-type VIN and differentiated-type VIN. It is sometimes graded VIN2 and VIN3, with the number 3 indicating furthest progression toward a true cancer.
How long does vulva neoplasia last?
Squamous cell carcinoma of the vulva usually forms slowly over many years. Pre-cancerous changes often occur first and can last for several years. The medical term most often used for this pre-cancerous condition is vulvar intraepithelial neoplasia (VIN).
How many types of vulvar cancer are there?
Some doctors think there are 2 kinds of vulvar cancer. One kind is associated with HPV infection (more than half of all vulvar cancers are linked to infection with the high-risk HPV types) and tends to occur in younger women.
What is the medical term for genital warts?
These warts may barely be visible or they may be several inches across. The medical term for genital warts is condyloma acuminatum. Two types of HPV (HPV 6 and HPV 11) cause most cases of genital warts, but are seldom linked to cancer and are known as low-risk HPV.
What does it mean when you have a lump on your vulva?
Almost all women with invasive vulvar cancers will have symptoms. These can include: An area on the vulva that looks different from normal – it could be lighter or darker than the normal skin around it, or look red or pink. A bump or lump, which could be red, pink, or white and could have a wart-like or raw surface or feel rough or thick.
What are the symptoms of a vulvar cancer?
Vulvar melanoma. Patients with vulvar melanoma can have many of the same symptoms as other vulvar cancers, such as: A lump. Itching. Pain. Bleeding or discharge. Most vulvar melanomas are black or dark brown, but they can be white, pink, red, or other colors.
What is a lump on the side of the vagina?
A distinct mass (lump) on either side of the opening to the vagina can be the sign of a Bartholin gland carcinoma. More often, however, a lump in this area is from a Bartholin gland cyst, which is much more common (and is not a cancer).
Does vulvar intraepithelial neoplasia go away?
Vulvar intraepithelial neoplasia. Most women with vulvar intraepithelial neoplasia (VIN) have no symptoms at all. When a woman with VIN does have a symptom, it is most often itching that does not go away or get better. An area of VIN may look different from normal vulvar skin. It is often thicker and lighter than the normal skin around it.
What are the risk factors for cervical dysplasia?
There are several risk factors for cervical dysplasia, some of which relate directly to the risk of HPV: having an illness that suppresses the immune system. being on immunosuppressant drugs. having multiple sexual partners. giving birth before the age of 16. having sex before the age of 18. smoking cigarettes.
How to prevent cervical dysplasia?
While abstinence is the only definite way to prevent cervical dysplasia, you can do a number of things to reduce your risk of getting HPV and cervical dysplasia: Use a condom or other protection when having sex. Consider getting the HPV vaccine if you are between the ages of 11 and 26. Avoid smoking cigarettes.
Why does the cervix dilate during childbirth?
It’s the cervix that dilates during childbirth to allow the fetus to pass through. In cervical dysplasia, the abnormal cells aren’t cancerous, but can develop into cancer if not caught early and treated.
Is HPV a sexually transmitted virus?
HPV is a sexually transmitted virus, and there are hundreds of strains. Some are low-risk and cause genital warts. Others are high-risk and cause cell changes that can turn into cervical dysplasia and cancer. According to the Journal of the American Medical Association (JAMA) Trusted Source.
Can cervical dysplasia return?
Dysplasia is usually caught early because of regular Pap tests. Treatment typically cures cervical dysplasia, but it can return. If no treatment is given, the dysplasia may get worse, potentially turning into cancer.
