Knowledge Builders

what chemicals are used in chemotherapy

by Marianne McClure Published 3 years ago Updated 2 years ago
image

I was able to find more than 200 different chemotherapy drugs, so these are five of the most prominent:

  • Asparaginase (crisantaspase)
  • Cytarabine (Ara-C)
  • Doxorubicin (Adriamycin)
  • Mercaptopurine (6-MP)
  • Teniposide (Vumon)

Alkylating agents
  • Altretamine.
  • Bendamustine.
  • Busulfan.
  • Carboplatin.
  • Carmustine.
  • Chlorambucil.
  • Cisplatin.
  • Cyclophosphamide.
Nov 22, 2019

Full Answer

What are the chemicals that speed up chemical reactions called?

The substances which trigger/inhibit/regulate the reactions are called hormones and the ones that speed up the reactions are called enzymes. What are hormones? Hormones are also called chemical messengers of the body. They regulate various types of reactions in the body and this regulatory action could either be of activation or of inhibition.

What chemicals are in EDTA?

Other details:

  • Davidking E-Cu-15 is a stable water-soluble metal chelate
  • Solubility in water: approx.1200 g/L (20OC)
  • Bulk density: approx.600~800 kg/m3 (untapped)
  • Chemical name: Ethylene thiamine tetraacetic acid, copper-disodium complex
  • EDTA-CuNa2

What chemicals are used in chemical warfare?

Thus, the CW agents used in warfare are classified as follows:

  • Nerve agents
  • Vesicants (blistering agents)
  • Bloods agents (cyanogenic agents)
  • Choking agents (pulmonary agents)
  • Riot-control agents (tear gases)
  • Psychomimetic agents
  • Toxins

What does chemotherapy do to the body?

How Chemotherapy Affects Your Body After Treatment

  • Brain. If you feel a little foggy when your treatment is done, you might have a touch of " chemo brain ." You may notice that you find it hard ...
  • Heart. Certain chemo drugs can damage cells in your heart. ...
  • Hair. If you lose some or all of your hair after chemo, it will typically start to grow back in a month or two.
  • Weight. ...
  • Energy. ...
  • Fertility

image

What are the most commonly used chemotherapy drugs?

Doctors typically combine several drugs, including:methotrexate.pralatrexate.doxorubicin.liposomal doxorubicin.vincristine.mitoxantrone.etoposide.bleomycin.More items...•

Is chemo made from chemicals?

Chemotherapy is a drug treatment that uses powerful chemicals to kill fast-growing cells in your body.

How toxic are chemotherapy drugs?

Chemotherapy drugs are considered to be hazardous to people who handle them or come into contact with them. For patients, this means the drugs are strong enough to damage or kill cancer cells. But this also means the drugs can be a concern for others who might be exposed to them.

What are the 6 classes of chemotherapy drugs?

Types of chemotherapy drugsAlkylating agents. This group of medicines works directly on DNA to keep the cell from reproducing itself. ... Nitrosoureas. ... Anti-metabolites. ... Plant alkaloids and natural products. ... Anti-tumor antibiotics. ... Hormonal agents. ... Biological response modifiers.

What is the main ingredient in chemotherapy?

Corticosteroids. Corticosteroids, often simply called steroids, are natural hormones and hormone-like drugs that are useful in the treatment of many types of cancer, as well as other illnesses. When these drugs are used as part of cancer treatment, they are considered chemotherapy drugs.

What is the chemical formula for chemotherapy?

Chemistry: Plant derived agent, epipodophyllotoxin, molecular weight 588.6, chemical formula C29H32O13. Lipid soluble, supplied as solution with polyethylene glycol, polysulfate, benzyl alcohol, citric acid, ethyl alcohol. The pH of the clear yellow solution is 3 to 4.

What is the most toxic chemo drug?

Direct pairwise meta-analysis results also revealed that the gemcitabine + carboplatin chemotherapy regimen was the most toxic regimen in hematologic for AOC patients among 8 chemotherapy regimens.

What is the Red Devil in chemo?

The chemotherapy (“chemo”) drug “The Red Devil” is doxorubicin (Adriamycin). It is an intravenous cancer medicine with a clear, bright red color, which is how it got its nickname.

How can I flush chemo out of my system?

Stay well hydrated. Drinking plenty of water before and after treatment helps your body process chemotherapy drugs and flush the excess out of your system.

How many rounds of chemo is normal?

During a course of treatment, you usually have around 4 to 8 cycles of treatment. A cycle is the time between one round of treatment until the start of the next. After each round of treatment you have a break, to allow your body to recover.

What is aggressive chemo?

Aggressive care includes chemotherapy after multiple earlier rounds of treatment have stopped working and being admitted to an intensive care unit. Such interventions at the end of life “are widely recognized to be harmful,” Chen said.

Is there snake venom in chemotherapy?

In summary, the studies on the inhibitory effect of crude snake venoms towards tumor cells showed doubtful results at the early stages. The snake venom was used as the mixture and their main clinical effect for cancer therapy was pain relief for the patients with hopelessly malignant tumors.

Is cobra poison used in chemotherapy?

Cobra venom is used in the preparation of chemicals needed for Chemotherapy of terminally ill Cancer patients. The value of the venom is so high since it is used to treat cancer patients in China.

Is chemo a radiation?

Chemotherapy and radiation therapy are both treatments for cancer – the uncontrolled growth and spread of cells to surrounding tissues. Chemotherapy, or “chemo,” uses special drugs to shrink or kill cancer cells. Radiation therapy, or “radiation,” kills these cells with high-energy beams such as X-rays or protons.

Who makes chemotherapy?

Bristol-Myers Squibb, Merck, AstraZeneca, Eli Lilly, Johnson & Johnson, and Celgene make up spots nine through four.

What does chemo mean in science?

chemo- a combining form with the meanings “chemical,” “chemically induced,” “chemistry,” used in the formation of compound words: chemotherapy. Also especially before elements of Latin origin, chemi-.

Why is chemo used?

Why it's done. Chemotherapy is used to kill cancer cells in people with cancer. There are a variety of settings in which chemotherapy may be used in people with cancer: To cure the cancer without other treatments. Chemotherapy can be used as the primary or sole treatment for cancer. After other treatments, to kill hidden cancer cells.

What is the purpose of chemotherapy?

After other treatments, to kill hidden cancer cells. Chemotherapy can be used after other treatments, such as surgery, to kill any cancer cells that might remain in the body. Doctors call this adjuvant therapy. To prepare you for other treatments. Chemotherapy can be used to shrink a tumor so that other treatments, such as radiation and surgery, ...

Why is chemo used for bone marrow transplant?

Chemotherapy is often used to prepare for a bone marrow transplant. Immune system disorders. Lower doses of chemotherapy drugs can help control an overactive immune system in certain diseases, such as lupus and rheumatoid arthritis.

What is the treatment for cancer?

Overview. Chemotherapy is a drug treatment that uses powerful chemicals to kill fast-growing cells in your body. Chemotherapy is most often used to treat cancer, since cancer cells grow and multiply much more quickly than most cells in the body. Many different chemotherapy drugs are available.

How to prepare for chemo?

Prepare for your first treatment. Ask your doctor or chemotherapy nurses how to prepare for chemotherapy. It may be helpful to arrive for your first chemotherapy treatment well rested. You might wish to eat a light meal beforehand in case your chemotherapy medications cause nausea.

How does chemotherapy help with cancer?

To ease signs and symptoms. Chemotherapy may help relieve signs and symptoms of cancer by killing some of the cancer cells. Doctors call this palliative chemotherapy.

What to ask your doctor about chemo?

Ask your doctor if you'll need time off work or help around your home after treatment. Ask your doctor for the details of your chemotherapy treatments so that you can make arrangements for work, children, pets or other commitments.

What is chemo used for?

Besides treatment for cancer, chemotherapy may be used to prepare people with bone marrow diseases for a bone marrow stem cell treatment, and it may be used for immune system disorders.

Why is chemotherapy used?

It could be used to shrink a tumor so it can be surgically removed, or to prepare you for radiation therapy.

What is the treatment for cancer called?

What is chemotherapy? Chemotherapy is an aggressive form of chemical drug therapy meant to destroy rapidly growing cells in the body. It’s usually used to treat cancer, as cancer cells grow and divide faster than other cells. A doctor who specializes in cancer treatment is known as an oncologist.

Why do you need chemotherapy for breast cancer?

If you’ve undergone surgery to remove a cancerous tumor, such as a lumpectomy for breast cancer, your oncologist may recommend chemotherapy to ensure that any lingering cancer cells are killed, as well. Chemotherapy is also used to prepare you for other treatments.

What are the side effects of chemotherapy?

hair. skin. lining of your intestinal tract. Because of this, the side effects of chemotherapy include: easy bruising and excessive bleeding. diarrhea. dry mouth.

How to prepare for chemo?

Consider these preparation tips for chemotherapy treatment: Make arrangements for work. Most people can work during chemotherapy, but you may want to be put on a lighter workload until you know what types of side effects you may be experiencing. Prepare your house.

Where do you put a port for chemo?

A port is a device that’s implanted in your body, typically in your chest near your shoulder. This allows for easier access to your veins and is less painful. During each treatment, the IV will be inserted into your port.

What is the agent for antimicrotubules?

Antimicrotubule agent: Estramustine. Retinoids: Bexarotene, Isotretinoin, Tretinoin (ATRA) Beyond the aforementioned types of chemotherapy, many other types of chemo treatments exist, such as targeted therapy, immunotherapy, and hormone therapy.

What is chemocare.com?

Chemocare.com is designed to provide the latest information about chemotherapy to patients and their families, caregivers and friends. For information about the 4th Angel Mentoring Program visit www.4thangel.org

What are plant alkaloids?

Plant Alkaloids. Plant alkaloids are chemotherapy treatments derived made from certain types of plants. The vinca alkaloids are made from the periwinkle plant (catharanthus rosea). The taxanes are made from the bark of the Pacific Yew tree (taxus). The vinca alkaloids and taxanes are also known as antimicrotubule agents.

What is the term for a treatment that is very similar to normal substances within the cell?

Antimetaboli tes. Antimetabolites are types of chemotherapy treatments that are very similar to normal substances within the cell. When the cells incorporate these substances into the cellular metabolism, they are unable to divide. Antimetabolites are cell-cycle specific.

What is an antitumor?

Antitumor antibiotics are chemo treatments made from natural products produced by species of the soil fungus Streptomyces. These drugs act during multiple phases of the cell cycle and are considered cell-cycle specific. There are several types of antitumor antibiotics:

What are alkylating agents?

Alkylating Agents. Alkylating agents are most active in the resting phase of the cell. These types of drugs are cell-cycle non-specific. There are several types of alkylating agents used in chemotherapy treatments: Mustard gas derivatives: Mechlorethamine, Cyclophosphamide, Chlorambucil, Melphalan, and Ifosfamide.

What metal salts are used in nitrosureas?

They can be useful in treating brain tumors. Metal salts: Carboplatin, Cisplatin, and Oxaliplatin.

What is the most commonly used agent in chemotherapy?

Alkylating agents were among the first anti-cancer drugs and are the most commonly used agents in chemotherapy today. Alkylating agents act directly on DNA, causing cross-linking of DNA strands, abnormal base pairing, or DNA strand breaks, thus preventing the cell from dividing.

What is chemotherapy used for?

Since different chemical agents damage cancer cells in different ways and at different phases in the cell cycle, a combination of drugs is often employed to increase the cancerous cell-killing effectiveness. This is called combination chemotherapy.

What are some examples of plant alkaloids?

Although they act throughout the cell cycle, some are more effective during the S- and M- phases, making these drugs cell cycle specific. Examples of plant alkaloids used in chemotherapy are actinomycin D, doxorubicin, and mitomycin.

How do antimetabolites affect the function of enzymes?

Antimetabolites replace natural substances as building blocks in DNA molecules, thereby altering the function of enzymes required for cell metabolism and protein synthesis. In other words, they mimic nutrients that the cell needs to grow, tricking the cell into consuming them, so it eventually starves to death.

What are the weapons used to fight cancer?

Just like scalpels, lasers, and electric currents are used in surgery, the weapons used to fight cancer in chemotherapy are a host of anti-cancer drugs. How differently these drugs kill cancer cells, or prevent them from dividing, depends on their classification. Drugs in the same class kill cancer cells by the same mechanism: they all attack ...

What are antitumor antibiotics?

They act by binding with DNA and preventing RNA ( ribonucleic acid) synthesis, a key step in the creation of proteins, which are necessary for cell survival. They are not the same as antibiotics used to treat bacterial infections. Rather, these drugs cause the strands of genetic material that make up DNA to uncoil, thereby preventing the cell from reproducing. Doxorubicin, mitoxantrone, and bleomycin are some examples of antitumor antibiotics.

How do drugs in the same class kill cancer cells?

Drugs in the same class kill cancer cells by the same mechanism: they all attack the same target within the cell. Depending on the type of cancer and the kind of drug used, chemotherapy drugs may be administered differently.

What is the drug called that can't tell the difference between cancerous cells and normal cells?

This type of chemo drug is called an antitumor antibiotic . This drug is unable to tell the difference between cancerous cells and normal cells. This is what causes the extreme side effects. Doxorubicin may be given intravenously through a central line or peripheral venous line, given over several minutes.

What is chemo error?

An error occurred while retrieving sharing information. Please try again later. It is safe to say that almost everyone has been affected by cancer in some way, but few of these people know anything about its treatment, chemotherapy. Chemotherapy is often simply referred to as “chemo,” which is the use of intracellular, ...

What is the name of the enzyme that is made from escherichia coli?

Asparaginase is an enzyme made from the bacteria escherichia coli (E. Coli). There are a couple different forms of this. Pegaspargase is the E. coli form linked to a polyethylene glycol molecule. This was developed for people with an allergy to E. coli; however, it is much more expensive.

What is doxorubicin made of?

Doxorubicin is an anthracycline antibiotic. It is made from a natural product produced by the soil fungus Streptomyces. It is also available with a polyethylene glycol coating. Both of these drugs were initially found in nature, but were probably refined in a lab.

How does doxorubicin work?

Doxorubicin works by damaging the RNA or DNA that tells the cell to keep dividing. It blocks the enzyme topoisomerase 2 that cancer cells need to keep dividing. The faster the division the better the chemo drugs will work at shrinking the tumor. This type of chemo drug is called an antitumor antibiotic.

Why did chemists find a way to replicate and produce enzymes and bacteria?

Chemists found a way to replicate and produce the enzymes and bacteria, in an easier way, in order to develop them for further use. Without chemistry, these drugs would never have been possibilities for cancer treatment. We have chemistry to thank for the complete development of chemotherapy.

Is chemo a curative treatment?

Moreover, chemo is sometimes given with curative intent. Other times, it is given as palliative therapy to ease the symptoms of more advanced cancer stages.Through understanding how chemotherapy works, we hope that a more efficient and less damaging treatment will transpire. Composition of ...

Where does chemo drug waste come from?

Most of the drug waste comes out in your body fluids, such as urine, stool, tears, sweat, and vomit. The drug waste is also in your blood, and may be in other body fluids such as fluids from semen and the vagina. When chemo drugs or their waste are outside your body, they can harm or irritate skin. Other people and pets could be exposed to ...

How to take chemo at home?

Oral chemo, or chemo you take by mouth and swallow , is usually taken at home. These drugs are as strong as other forms of chemo, and many are considered hazardous. There are usually special precautions for storing and handling oral chemo drugs. You might be told to be careful not to let others come into contact with it or your body fluids while taking it and for a time after taking it. Sometimes you need to wear gloves when touching the pills or capsules. Some drugs have to be kept in the bottle or box they came in. And some drugs and the packages they come in need to be disposed of in a certain way. Some might have to be taken back to the drug store to be thrown away safely. If you are taking an oral chemo drug, talk to your cancer care team about any special precautions needed at home. To learn more, see Getting Oral or Topical Chemotherapy .

How long does it take for chemo to break down?

What to do during – and for 48 to 72 hours after – chemo: It generally takes about 48 to 72 hours for your body to break down and/or get rid of most chemo drugs. But it's important to know that each chemo drug is excreted or passed through the body a bit differently.

What do nurses wear to give chemo?

And nurses and others who give your chemo and help take care of you afterwards wear protective clothing, such as 2 pairs of special gloves and a gown, and sometimes goggles or a face shield.

Is chemotherapy safe?

Chemotherapy Safety. Chemotherapy drugs are considered to be hazardous to people who handle them or come into contact with them. For patients, this means the drugs are strong enough to damage or kill cancer cells. But this also means the drugs can be a concern for others who might be exposed to them. This is why there are safety rules and ...

Can you stay in the waiting room for chemo?

However, some treatment centers only allow patients in the infusion area and visitors may need to stay in the waiting room. You are the only person who should be exposed to the chemo you are getting, but it can be irritating if it gets on your skin.

Can you be around family during chemo?

There are certain safety precautions that might be needed during and after getting chemo. Unless your health care team tells you differently, you can usually be around family and friends during the weeks and months you're getting chemo. On treatment days, family and friends can often come with you.

image

Overview

  • Chemotherapy is a drug treatment that uses powerful chemicals to kill fast-growing cells in your body. Chemotherapy is most often used to treat cancer, since cancer cells grow and multiply much more quickly than most cells in the body. Many different chemotherapy drugs are available. Chemotherapy drugs can be used alone or in combination to treat a...
See more on mayoclinic.org

Why It's Done

  • Chemotherapy is used to kill cancer cells in people with cancer. There are a variety of settings in which chemotherapy may be used in people with cancer: 1. To cure the cancer without other treatments.Chemotherapy can be used as the primary or sole treatment for cancer. 2. After other treatments, to kill hidden cancer cells.Chemotherapy can be used after other treatments, such a…
See more on mayoclinic.org

Risks

  • Side effects of chemotherapy drugs can be significant. Each drug has different side effects, and not every drug causes every side effect. Ask your doctor about the side effects of the particular drugs you'll receive.
See more on mayoclinic.org

How You Prepare

  • How you prepare for chemotherapy depends on which drugs you'll receive and how they'll be administered. Your doctor will give you specific instructions to prepare for your chemotherapy treatments. You may need to: 1. Have a device surgically inserted before intravenous chemotherapy.If you'll be receiving your chemotherapy intravenously — into a vein — your docto…
See more on mayoclinic.org

What You Can Expect

  • Determining which chemotherapy drugs you'll receive
    Your doctor chooses which chemotherapy drugs you'll receive based on several factors, including: 1. Type of cancer 2. Stage of cancer 3. Overall health 4. Previous cancer treatments 5. Your goals and preferences Discuss your treatment options with your doctor. Together you can decide what…
  • How chemotherapy drugs are given
    Chemotherapy drugs can be given in different ways, including: 1. Chemotherapy infusions.Chemotherapy is most often given as an infusion into a vein (intravenously). The drugs can be given by inserting a tube with a needle into a vein in your arm or into a device in a vein in …
See more on mayoclinic.org

Results

  • You'll meet with your cancer doctor (oncologist) regularly during chemotherapy treatment. Your oncologist will ask about any side effects you're experiencing, since many can be controlled. Depending on your situation, you may also undergo scans and other tests to monitor your cancer during chemotherapy treatment. These tests can give your doctor an idea of how your cancer is …
See more on mayoclinic.org

Clinical Trials

  • Explore Mayo Clinic studiesof tests and procedures to help prevent, detect, treat or manage conditions.
See more on mayoclinic.org

1.What chemicals are used in Chemotherapy? | Questions

Url:https://www.thenakedscientists.com/articles/questions/what-chemicals-are-used-chemotherapy

3 hours ago  · Answer. David K. - Well, I think the original approach to systemic cancer treatment - after radiation and surgery had failed - was to use very toxic, poisonous drugs to try to get …

2.What are common chemicals used in chemotherapy?

Url:https://www.healthtap.com/questions/1534540-what-are-common-chemicals-used-in-chemotherapy/

13 hours ago  · What are common chemicals used in chemotherapy? 1 doctor answer • 3 doctors weighed in. Share. Dr. Sewa Legha answered. Medical Oncology 51 years experience.

3.Videos of What Chemicals Are Used in Chemotherapy

Url:/videos/search?q=what+chemicals+are+used+in+chemotherapy&qpvt=what+chemicals+are+used+in+chemotherapy&FORM=VDRE

5 hours ago What kinds of chemicals are used in chemotherapy? There are several types of alkylating agents used in chemotherapy treatments: Mustard gas derivatives: Mechlorethamine, …

4.Chemotherapy - Mayo Clinic

Url:https://www.mayoclinic.org/tests-procedures/chemotherapy/about/pac-20385033

34 hours ago  · Many different drugs: There are over 100 different drugs under the name of chemotherapy.Each one is different, and different drugs are used for treating different …

5.What chemicals are used in chemotherapy to kill cells?

Url:https://www.healthtap.com/questions/1559937-what-chemicals-are-used-in-chemotherapy-to-kill-cells/

12 hours ago  · Chemotherapy is an aggressive form of chemical drug therapy meant to destroy rapidly growing cells in the body. It’s usually used to treat cancer, as cancer cells grow and …

6.Chemotherapy: Uses, Side Effects, and Procedure

Url:https://www.healthline.com/health/chemotherapy

27 hours ago Topoisomerase Inhibitors Topoisomerase I inhibitors: Ironotecan, topotecan Topoisomerase II inhibitors: Amsacrine, etoposide, etoposide phosphate, teniposide

7.Types of Chemotherapy - What is Chemotherapy?

Url:https://chemocare.com/chemotherapy/what-is-chemotherapy/types-of-chemotherapy.aspx

30 hours ago Examples of plant alkaloids used in chemotherapy are actinomycin D, doxorubicin, and mitomycin. Antitumor antibiotic They act by binding with DNA and preventing RNA ( ribonucleic …

8.Types of Chemotherapy Drugs | SEER Training - National …

Url:https://training.seer.cancer.gov/treatment/chemotherapy/types.html

4 hours ago I was able to find more than 200 different chemotherapy drugs, so these are five of the most prominent: Asparaginase (crisantaspase) Cytarabine (Ara-C) Doxorubicin (Adriamycin) …

9.www.ChemistryIsLife.com - The Chemistry of …

Url:https://www.chemistryislife.com/the-chemistry-of-chemotherapy

29 hours ago Chemotherapy Safety. Chemotherapy drugs are considered to be hazardous to people who handle them or come into contact with them. For patients, this means the drugs are strong …

10.Chemotherapy Safety | American Cancer Society

Url:https://www.cancer.org/treatment/treatments-and-side-effects/treatment-types/chemotherapy/chemotherapy-safety.html

13 hours ago

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 1 2 3 4 5 6 7 8 9