Is Lantus a metformin?
Metformin and Lantus (insulin glargine) are used to treat diabetes. A difference is metformin is used to treat only type 2 diabetes, while Lantus may be used to treat both type 1 and type 2 diabetes. Metformin is also used to treat polycystic ovaries and weight gain due to medications used for treating psychoses.
Is Lantus a type 2?
Lantus for type 2 diabetes Lantus is FDA-approved to improve blood sugar levels in adults with type 2 diabetes. Type 2 diabetes is a chronic (long-term) condition where your cells don't respond to insulin as well as they should. Insulin is a hormone that enables sugar to pass from your blood into your cells.
Is Lantus insulin fast acting or slow acting?
Prescription Lantus is a long-acting insulin used to treat adults with type 2 diabetes and adults and pediatric patients (children 6 years and older) with type 1 diabetes for the control of high blood sugar.
What is the difference between insulin and Lantus?
Insulin is one of the most effective blood sugar-lowering medication and can lower your A1c (average blood sugar over time) by up to 2-3%. Lantus (insulin glargine) is a long-lasting insulin that provides consistent, all-day sugar control with just once or twice daily dosing.
Can you take metformin and Lantus at the same time?
Can you take Lantus (insulin glargine) and metformin together? Lantus (insulin glargine) can be taken with other oral diabetes medications, like metformin, if your blood sugar level needs better control. Talk to your provider about your diabetes treatment and what medications may be right for you.
Is Lantus a high risk medication?
[ Extra care is needed because Lantus is a high-alert medicine. ]
Why is Lantus given at night?
Abstract. Aims/hypothesis: Insulin glargine is a long-acting human insulin analog often administered at bedtime to patients with type 2 diabetes. It reduces fasting blood glucose levels more efficiently and with less nocturnal hypoglycemic events compared with human neutral protamine Hagedorn (NPH) insulin.
What are the 3 types of insulin?
There are three main groups of insulins: Fast-acting, Intermediate-acting and Long-acting insulin.
Is Lantus a short-acting insulin?
Prescription Lantus is a long-acting insulin used to treat adults with type 2 diabetes and adults and pediatric patients (children 6 years and older) with type 1 diabetes for the control of high blood sugar. Do not use Lantus to treat diabetic ketoacidosis.
What is a good substitute for Lantus?
Semglee (insulin glargine-yfgn) is both biosimilar to, and interchangeable with (can be substituted for), its reference product Lantus (insulin glargine), a long-acting insulin analog. Semglee (insulin glargine-yfgn) is the first interchangeable biosimilar product approved in the U.S. for the treatment of diabetes.
What insulin is better than Lantus?
Toujeo and Lantus are long-acting insulins that can help keep your blood sugar controlled for 24 hours or longer. Toujeo is more concentrated than Lantus and may be a good option for people who need higher amounts of insulin.
Is Lantus and Humalog the same?
Lantus (insulin glargine [rdna origin]) and Humalog (insulin lispro [rDNA origin]) are both forms of insulin used to treat type 1 (insulin-dependent) or type 2 (non insulin-dependent) diabetes. A difference is that Humalog is usually given together with another long-acting insulin.
Is Lantus a basal insulin?
Insulin glargine (Lantus) is a long-acting, human insulin analogue that has been specifically designed to overcome the deficiencies of traditionally available 'intermediate-acting' insulins that are currently used for basal insulin supplementation.
Is Lantus a short acting insulin?
Prescription Lantus is a long-acting insulin used to treat adults with type 2 diabetes and adults and pediatric patients (children 6 years and older) with type 1 diabetes for the control of high blood sugar. Do not use Lantus to treat diabetic ketoacidosis.
When should you not take Lantus?
You should not use Lantus if you are allergic to insulin, or if you are having an episode of hypoglycemia (low blood sugar) or diabetic ketoacidosis (call your doctor for treatment). Lantus is not approved for use by anyone younger than 6 years old, and some brands are for use only in adults.
What type of insulin is glargine insulin?
Insulin glargine belongs to a drug class called long-acting insulins. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions. Insulin glargine works by controlling how sugar is used and stored in your body.
What is Lantus’ peak time, duration, and onset of action? Is it a fast-acting insulin?
Below are the duration and onset-of-action times for Lantus. Lantus doesn’t have a peak time. (Peak time is the amount of time it takes for a drug...
Is there a dosing conversion for Tresiba and Lantus?
Yes, there is a dosing conversion for switching from Lantus to Tresiba, or vice versa. If you’re interested in switching between these two drugs, t...
Is Lantus similar to Humalog, Novolog, and Victoza?
Below are a few ways that Lantus, Humalog, Novolog, and Victoza are alike and different. Lantus, Humalog, and Novolog are used to help control bloo...
How does Lantus work? What’s its half-life?
Lantus is used to help control blood sugar levels in certain people who have diabetes. Diabetes is a condition that leads to high blood sugar. With...
How should I store Lantus? Does it need to be refrigerated?
The way you’ll store Lantus varies based on a few factors, including whether you’re using Lantus vials or pens. For details, see the list below. Un...
Does Lantus cause cancer?
It’s possible, but it isn’t known for sure. Cancer wasn’t a side effect reported in initial studies of Lantus. Since then, there have been reports...
Lantus basics and classification
Lantus is classified as a long-acting insulin. It contains the active drug insulin glargine, which is a biologic drug. Biologic drugs are made from parts of living cells.
Lantus vs. Levemir
Lantus contains insulin glargine, while Levemir contains insulin detemir. If you’d like to see a side-by-side description of these two drugs, read this article.
Lantus vs. Tresiba
Lantus contains insulin glargine, while Tresiba contains insulin degludec. Check out this article to learn more about Lantus versus Tresiba.
Lantus vs. Toujeo
Both Lantus and Toujeo contain insulin glargine. See this article to find out how the two medications compare.
Is there a dosing conversion for Tresiba and Lantus?
Yes, there is a dosing conversion for switching from Lantus to Tresiba, or vice versa.
Is Lantus similar to Humalog, Novolog, and Victoza?
Below are a few ways that Lantus, Humalog, Novolog, and Victoza are alike and different.
How should I store Lantus? Does it need to be refrigerated?
The way you’ll store Lantus varies based on a few factors, including whether you’re using Lantus vials or pens. For details, see the list below.
Insulin Glargine (by Injection)
Home > Drugs A Z > Insulin Glargine (By injection) Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article. Insulin glargine is a long-acting type of insulin that works slowly, over about 24 hours. Insulin is one of many hormones that help the body turn the food we eat into energy.
Lantus
How does this medication work? What will it do for me? Insulin is a naturally occurring hormone made by the pancreas that helps our body use or store the glucose (sugar) it gets from food.
Insulin Glargine
Insulin glargine, marketed under the names Lantus, among others, is a long-acting basal insulin analogue, given once daily to help control the blood sugar level of those with diabetes.
Lantus (insulin Glargine)
Tweet Lantus is an analogue insulin produced by Sanofi-Aventis with the medical name insulin glargine. Lantus has been available for pharmaceutical use since the year 2000. Lantus hit the news in June 2009 over concerns that it may lead to the formation of cancer.
Insulin Glargine (lantus)
What is INSULIN GLARGINE-INJECTABLE, and how does it work (mechanism of action)? Insulin glargine is a bioengineered (man-made) injectable form of long-acting insulin that is used to regulate sugar (glucose) levels in type 1 and type 2 diabetes.
Lantus
Lantus is a prescription medication used to treat type 1 and type 2 diabetes. Lantus is a long-acting form of insulin and works by replacing the insulin that is normally produced by the body and by helping the body to use sugar for energy. It also stops the liver from producing more sugar.
Lantus (insulin Glargine) Side Effects
What Is Lantus (Insulin Glargine)? Lantus is the brand name of insulin glargine, a long-acting insulin used to treat adults and children with type 1 diabetes mellitus and adults with type 2 diabetes mellitus to control high blood sugar. Lantus replaces the insulin that your body no longer produces.
How many times does insulin glargine affect rabbits?
Rats and rabbits were exposed to insulin glargine in animal reproduction studies during organogenesis, respectively 50 times and 10 times the human subcutaneous dose of 0.2 units/kg/day. Overall, the effects of insulin glargine did not generally differ from those observed with regular human insulin [see Data].
What is the risk of hypoglycemia after Lantus injection?
The risk of hypoglycemia after an injection is related to the duration of action of the insulin and, in general, is highest when the glucose lowering effect of the insulin is maximal. As with all insulin preparations, the glucose lowering effect time course of Lantus may vary in different individuals or at different times in the same individual and depends on many conditions, including the area of injection as well as the injection site blood supply and temperature [see Clinical Pharmacology (12.2)]. Other factors which may increase the risk of hypoglycemia include changes in meal pattern (e.g., macronutrient content or timing of meals), changes in level of physical activity, or changes to coadministered medication [see Drug Interactions (7)]. Patients with renal or hepatic impairment may be at higher risk of hypoglycemia [see Use in Specific Populations (8.6, 8.7)].
How much Lantus should I take for diabetes?
The recommended starting dose of Lantus in patients with type 2 diabetes who are not currently treated with insulin is 0.2 units/kg or up to 10 units once daily. One may need to adjust the amount and timing of short- or rapid-acting insulins and dosages of any oral antidiabetic drugs.
What is the most common adverse reaction to insulin?
Hypoglycemia is the most commonly observed adverse reaction in patients using insulin, including Lantus [see Warnings and Precautions (5.3)]. Tables 5, 6, and 7 summarize the incidence of severe hypoglycemia in the Lantus individual clinical trials. Severe symptomatic hypoglycemia was defined as an event with symptoms consistent with hypoglycemia requiring the assistance of another person and associated with either a blood glucose below 50 mg/dL (≤56 mg/dL in the 5-year trial and ≤36 mg/dL in the ORIGIN trial) or prompt recovery after oral carbohydrate, intravenous glucose, or glucagon administration.
What is lantus used for?
Lantus is indicated to improve glycemic control in adults and pediatric patients with type 1 diabetes mellitus and in adults with type 2 diabetes mellitus.
How to get insulin out of a vial?
If bubbles are in the syringe, hold the syringe straight up and tap the side of the syringe until the bubbles float to the top. Push the bubbles out with the plunger and draw insulin back in until you have the correct dose.
Where is insulin glargine metabolized?
A metabolism study in humans indicates that insulin glargine is partly metabolized at the carboxyl terminus of the B chain in the subcutaneous depot to form two active metabolites with in vitro activity similar to that of human insulin, M1 (21 A -Gly-insulin) and M2 (21 A -Gly-des-30 B -Thr-insulin). Unchanged drug and these degradation products are also present in the circulation.
Does Lantus cause cancer as a side effect?
No, Lantus is not known to cause cancer. In clinical trials, the incidence of cancer was similar between treatment groups. And it hasn’t been reported since this medication has been available for use.
Weight gain
Weight gain may occur after starting Lantus treatment. Weight gain is a common side effect of all types of insulin. And Lantus is a type of insulin.
Joint pain
Some people may have joint pain while taking Lantus. In clinical trials, this side effect was commonly reported in people with type 2 diabetes. However, it wasn’t reported in people with type 1 diabetes.
Diarrhea
It’s possible to have diarrhea while taking Lantus. In clinical trials, this side effect was common in people with type 2 diabetes. However, it wasn’t reported in people with type 1 diabetes.
Injection site reactions
Injection site reactions may occur with Lantus. Injections site reactions are commonly reported with all types of insulin, including Lantus. They can affect people with type 1 and type 2 diabetes.
Hypoglycemia
As with all types of insulin, hypoglycemia (low blood sugar) is the most common side effect of Lantus. (Lantus is a type of insulin .)
Allergic reaction
As with most drugs, Lantus can cause an allergic reaction in some people. Allergic reactions, including anaphylaxis, can be life threatening.
What is lantus injection?
LANTUS (insulin glargine injection) is a sterile solution of insulin glargine for subcutaneous use. Insulin glargine is a recombinant human insulin analog that is a long-acting, parenteral blood-glucose-lowering agent [see CLINICAL PHARMACOLOGY ]. Insulin glargine has low aqueous solubility at neutral pH. At pH 4 insulin glargine is completely soluble. After injection into the subcutaneous tissue, the acidic solution is neutralized, leading to formation of microprecipitates from which small amounts of insulin glargine are slowly released, resulting in a relatively constant concentration/time profile over 24 hours with no pronounced peak. This profile allows once-daily dosing as a basal insulin. LANTUS is produced by recombinant DNA technology utilizing a non- pathogenic laboratory strain of Escherichia coli (K12) as the production organism. Insulin glargine differs from human insulin in that the amino acid asparagine at position A21 is replaced by glycine and two arginines are added to the C-terminus of the B-chain. Chemically, insulin glargine is 21 A - Gly -30 B a-L-Arg-30 B b-L-Arg-human insulin and has the empirical formula C267H404N72O78S6 and a molecular weight of 6063. Insulin glargine has the following structural formula:
How long does insulin glargine stay in the body?
After injection into the subcutaneous tissue, the acidic solution is neutralized, leading to formation of microprecipitates from which small amounts of insulin glargine are slowly released, resulting in a relatively constant concentration/time profile over 24 hours with no pronounced peak.
How many times does insulin glargine affect rabbits?
Rats and rabbits were exposed to insulin glargine in animal reproduction studies during organogenesis, respectively 50 times and 10 times the human subcutaneous dose of 0.2 units/kg/day. Overall, the effects of insulin glargine did not generally differ from those observed with regular human insulin (see Data ).
How long does it take for insulin to work?
The median time between injection and the end of pharmacological effect was 14.5 hours (range: 9.5 to 19.3 hours) for NPH insulin, and 24 hours (range: 10.8 to >24.0 hours) (24 hours was the end of the observation period) for insulin glargine.
How to get insulin out of a vial?
If bubbles are in the syringe, hold the syringe straight up and tap the side of the syringe until the bubbles float to the top. Push the bubbles out with the plunger and draw insulin back in until you have the correct dose.
Where is insulin glargine metabolized?
A metabolism study in humans indicates that insulin glargine is partly metabolized at the carboxyl terminus of the B chain in the subcutaneous depot to form two active metabolites with in vitro activity similar to that of human insulin, M1 (21 A -Gly-insulin) and M2 (21 A -Gly-des30 B -Thr-insulin). Unchanged drug and these degradation products are also present in the circulation.
Can you take Lantus with insulin?
Type 1 Diabetes. In patients with type 1 diabetes, LANTUS must be used concomitantly with short-acting insulin. The recommended starting dose of LANTUS in patients with type 1 diabetes should be approximately one-third of the total daily insulin requirements.
How does Lantus work?
How Lantus (insulin glargine) works. Lantus (insulin glargine) releases a hormone called insulin into the body to lower glucose (sugar) levels in the blood.
What is the best insulin for low blood sugar?
Pros. One of the most effective medications for controlling your blood sugar. Lantus (insulin glargine) is a long lasting insulin that provides consistent, all-day blood sugar control with less risk of low blood sugar. Doses can be easily adjusted to make a customized regimen that's tailored to your body's needs.
What is lantus insulin?
What kind of insulin is Lantus (insulin glargine)? Lantus (insulin glargine) is a long-acting insulin that works for up to 24 hours to lower your blood sugar. Does Lantus (insulin glargine) make you gain weight? Weight gain is one of the most common side effects of Lantus (insulin glargine). In clinical studies, the average weight gain was up ...
What to do if your blood sugar is not rising after eating?
If your blood sugar is not rising when you eat or your blood sugar drops even lower after eating, call 911. Prices for Lantus (insulin glargine) start at just $ 333.75 with a GoodRx coupon. They’re fast, easy-to-use and free! View Coupon Prices.
How much weight gain is a side effect of Lantus?
Weight gain is one of the most common side effects of Lantus (insulin glargine). In clinical studies, the average weight gain was up to 1.5 lbs in adults with type 1 diabetes who took Lantus (insulin glargine) for 16 to 28 weeks.
How long to wait to recheck sugar after eating?
After eating 15 grams of fast-acting sugar, wait 15 minutes and recheck your blood sugar.
How to prevent blood sugar fluctuations?
However, your doctor may prescribe other short-acting insulins to use at different times of the day depending on your blood sugar control. Keep a consistent meal and exercise schedule to prevent any fluctuations in your blood sugar. Do not re-use needles. Always use a new needle for each injection.
Introduction
If you have diabetes, your doctor might suggest Lantus ( insulin glargine) as a treatment option.
What if I miss a dose?
If you miss a dose of Lantus, inject your missed dose as soon as you remember. If it’s almost time for your next dose, you can skip the missed dose. Then inject your next dose at your usual time.
What factors can affect my dosage?
The dosage of Lantus you’re prescribed may depend on several factors. These include:
How is Lantus used?
Lantus is given as an injection under your skin. You can inject it into your belly, upper arms, or upper thighs.
What should be done in case of overdose?
Don’t inject more Lantus than your doctor prescribes. Using more than this can lead to serious side effects.
What should I ask my doctor?
The sections above describe the typical dosages provided by the drug manufacturer. If your doctor recommends Lantus for you, they’ll prescribe the dosage that’s right for you.
Ask a pharmacist
Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional.
How many units of insulin is in a Lantus pen?
The drug comes as a solution inside 10-milliliter (mL) vials that hold 100 units of insulin glargine per mL. The vial is used with needles, which aren’t included with the vial. Lantus also comes as a prefilled SoloStar pen. Each pen contains 3 mL of drug solution that has 100 units of insulin per mL of solution.
Why do people with type 1 diabetes need Lantus?
People with type 1 diabetes will need to take Lantus along with a mealtime insulin. This is because Lantus is a basal insulin, a “background” insulin that helps control blood sugar levels in between meals. A mealtime insulin is needed to control spikes in blood sugar that occur after eating.
How many episodes of hypoglycemia are there with Lantus?
Clinical studies looked at adults who took Lantus for type 1 diabetes. A 16-week study found that 6.5% of the adults experienced at least one episode of severe hypoglycemia. And a 28-week study found that 10.6% of adults experienced severe hypoglycemia at least once.
What is lantus used for?
Lantus is a brand-name prescription medication. It’s used to improve blood sugar levels in : adults and children ages 6 years and older with type 1 diabetes. adults with type 2 diabetes. For more information about type 1 and type 2 diabetes and how Lantus is used to manage these conditions, see the “ Lantus uses ” section below.
What are some ways to improve blood sugar levels in type 1 diabetes?
Examples of other insulins that may be used to improve blood sugar levels in people with type 1 or type 2 diabetes include: long-acting insulins, which help improve blood sugar levels for about 24 hours: insulin glargine (Basaglar, Toujeo)
How much weight can you gain with Lantus?
Weight gain is one of the most common side effects of Lantus. In clinical studies, the average weight gain was: up to 1.5 pounds (lb) in adults with type 1 diabetes who took Lantus over 16 to 28 weeks. up to 4.8 lb in children with type 1 diabetes who took Lantus and regular insulin for 28 weeks.
How long does it take for Lantus to go away?
hypoglycemia (low blood sugar levels) Most of these side effects may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk with your doctor or pharmacist. * This is a partial list of more common side effects from Lantus.
