what does 1 octanol smell like

Full Answer

What is the odor and taste threshold for 1 octanol?

The odor and taste threshold for 1-octanol was reported at about 24 ppm. 0.69 mg/cu m (Odor low) 0.69 mg/cu m (Odor high) Odor perception threshold is 0.05 mg/L (for primary and secondary octyl alcohol).

What are the isomers of octanol?

Many other isomers are also known generically as octanols. 1-Octanol is manufactured for the synthesis of esters for use in perfumes and flavorings. It has a pungent odor. Esters of octanol, such as octyl acetate, occur as components of essential oils.

What is an octanol?

Some octanols occur naturally in the form of esters in some essential oils. This organic compound is an oily, colorless liquid immiscible in water, with a pungent, aromatic odor. Other commercially essential octanols are 2-octanol and 2-ethyl hexanol.

Why does 1-octanol have an annoying odor?

The annoying odor of 1-octanol may mask sensory irritation and prevent subjects with enhanced chemical sensitivity from concentrating on performance in a demanding task.

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What does 2 octanol smell like?

Odor sample from: Nickstadt Moeller, Inc. Use: 2 � Octanol is a possible alternative for the petrochemical 2-ethylhexanol in plasticizers....Supplier Sponsors.Google Scholar:SearchFDA Mainterm (SATF):123-96-6 ; 2-OCTANOLFDA Regulation:16 more rows

What type of alcohol is 1-octanol?

1-Octanol, also known as octan-1-ol, is the organic compound with the molecular formula CH3(CH2)7OH. It is a fatty alcohol.

Is 1-octanol a solid liquid or gas?

liquid3.2.1Physical Description Octanol appears as a clear colorless liquid with a penetrating aromatic odor. Insoluble in water and floats on water. Vapors heavier than air.

Is 1-octanol soluble in water?

The solubility of water in 1-octanol was measured from 2 °C to 96 °C by coulometric Karl Fischer titration. The mass fraction solubility at 25 ° was found to be (48.91 ± 0.13) mg/g.

Is octanol toxic?

Skin: May cause mild skin irritation. May be absorbed through the skin. Prolonged or repeated contact may dry/defat the skin and cause irritation. Ingestion: May cause digestive tract disturbances.

Is octanol an alcohol?

1-Octanol, also known as octan-1-ol, is the organic compound with the molecular formula CH3(CH2)7OH. It is a fatty alcohol. Many other isomers are also known generically as octanols. 1-Octanol is manufactured for the synthesis of esters for use in perfumes and flavorings.

Why does octanol not dissolve in water?

Answer: The product from 2-octanol is a ketone, which is insoluble in water because it is a nonpolar compound (even though there is a carbonyl group). The product from 1-octanol is a carboxylic acid, which reacts with base to form a carboxylate ion which is soluble in water.

What is the pH of octanol?

Previous efforts have been made to determine octanol–water partitioning coefficients (Kow) for MCLR, with ranges of 2.18 to −1.76 at pH = 1 to 10 (de Maagd et al. 1999), 1.63 to −1.56 at pH = 1 to 12 (Liang et al.

Would you expect 1-octanol to me miscible or immiscible in water explain?

Bookmark this question. Show activity on this post. Octan-1-ol is polar due to the presence of the −OH group, but it is immiscible with water.

Is 1-octanol polar or nonpolar?

For 1-octanol ε = 10 (nonpolar). The biological properties of lipids can be understood due to their overall nonpolar nature.

What is the boiling point of 1-octanol?

383°F (195°C)1-Octanol / Boiling point

Is alcohol and ethanol same?

Ethanol is a combustible, toxic compound. It has many names, including ethyl, drinking, or grain alcohol. It is best known as simply alcohol and is found in drinks. Ethanol is a colorless, flammable chemical compound that is best known for its use in alcoholic beverages.

What is the formula for octanol?

1-Octanol, also known as octan-1-ol, is the organic compound with the molecular formula CH 3 (CH 2) 7 OH. It is a fatty alcohol. Many other isomers are also known generically as octanols. 1-Octanol is manufactured for the synthesis of esters for use in perfumes and flavorings. It has a pungent odor.

How is octanol made?

Octanol is mainly produced industrially by the oligomerization of ethylene using triethylaluminium followed by oxidation of the alkylaluminium products. This route is known as the Ziegler alcohol synthesis. An idealized synthesis is shown:

Is 1 octanol flammable?

With a flash point of 81 °C, 1-oc tanol is not seriously flammable, though its autoignition point is as low as 245 °C. 1-Octanol is mainly consumed as a precursor to perfumes.

Octanol Terpene

Octa- comes from Greek, where it has the meaning “eight”, which is the number of perfection, the infinity, and the harmonic balance. Octanols are alcohols with the formula C8H17OH.

What does Octanol do?

This terpene inhibits the overexpression of COX 2, which is the precursor to prostaglandins. Put in simple words, the overall effect of this inhibition is a dramatic drop in inflammation. Added to this, it has a role as a plant metabolite.

Octanol Effects

Terpenes present in cannabis have a wide range of known biological effects. Scientists have pointed out Octanol for its potent anti-inflammatory and analgesic effects. When used in conjunction with pinene and linalool, it has a powerful anti-inflammatory entourage effect.

Octanol Benefits

The terpene Octanol-1 has been examined for controlling essential tremors (ET) and other types of involuntary neurological tremors characterized by involuntary rhythmic contractions and relaxations of certain muscle groups.

Octanol Smell

Terpenes are volatile compounds responsible for the typical smell and taste of cannabis. According to The Joint FAO/WHO Expert Committee on Food Additives (JECFA), 1-Octanol has a sharp fatty-citrus odor. Its penetrating aromatic scent that reminds of fresh orange rose fragrance competes with its complex flavor profile.

Octanol Strains

Currently, there’s no information available about high-octanol strains on the cannabis market, which makes us think about the large path we need to walk to discover more cannabis-derived terpenes in the future.

What is the USEPA code for 1-octanol?

For 1-octanol (USEPA/OPP Pesticide Code: 079037) ACTIVE products with label matches. /SRP: Registered for use in the USA but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./

What is octanol used for?

IDENTIFICATION AND USE: 1-Octanol is a colorless liquid used in the determination of partition coefficients, perfumery, cosmetics, organic synthesis, solvent manufacture of high-boiling esters, antifoaming agent, and as a flavoring agent. 1-octanol is registered for pesticide use in the USA but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses. It has been used as experimental medication to treat tremor in patients. HUMAN EXPOSURE AND TOXICITY: In a human patch test, 1-octanol in 2% petrolatum was neither a skin irritant nor a skin sensitizer. Octanol has caused transient injury of corneal epithelium, with recovery in 48 hr. Common signs of exposure to 1-octanol are CNS: headache, muscle weakness, giddiness, ataxia, confusion, delirium, coma. Gastrointestinal: nausea, vomiting, diarrhea (odor of the alcohol in excreta). Irritation of skin, eyes, throat from vapor or liquid with cough and dyspnea. The annoying odor of 1-octanol may mask sensory irritation and prevent subjects with enhanced chemical sensitivity from concentrating on performance in a demanding task. ANIMAL STUDIES: 1-Octanol was slightly irritating to the skin of rabbits and is considered an eye irritant using the EU criteria. n-Octanol (0.55 g/kg) produced the largest decrease in body temperature. No evidence of tumors in the lung adenoma study in which mice were injected intraperitoneally with 100 and 500 mg/kg 1-octanol three times a week for 8 weeks. Studies indicate that T-type calcium channels (T-channels) in the thalamus are cellular targets for general anesthetics. The study recorded T-currents and underlying low-threshold calcium spikes from neurons of nucleus reticularis thalami (nRT) in brain slices from young rats and investigated the mechanisms of their modulation by an anesthetic alcohol, 1-octanol. 1-Octanol inhibited native T-currents at subanesthetic concentrations with an IC (50) of approximately 4 uM. Inhibition of both native and recombinant T-currents was accompanied by a hyperpolarizing shift in steady-state inactivation, indicating that 1-octanol stabilized inactive states of the channel. In developmental studies in rats no treatment-related effects were observed in pregnant females, including frequency of resorptions, fetal weights, or skeletal/visceral malformations. 1-Octanol was negative in an Ames Salmonella assay with strains Ta 98, TA 100, TA 1535, TA 1537, and TA 1538 at concentrations ranging from 4 to 2500 ug/plate with and without metabolic activation.

How long does it take for octanol to heal?

Octanol has caused transient injury of corneal epithelium, with recovery in 48 hr. Common signs of exposure to 1-octanol are CNS: headache, muscle weakness, giddiness, ataxia, confusion, delirium, coma. Gastrointestinal: nausea, vomiting, diarrhea (odor of the alcohol in excreta).

How do alkanols affect the central nervous system?

The effect of various alkanols on the central nervous system was studied by using rat brain synaptosomal membranes as an in vitro model. The activity of (Ca2+/Mg2+)ATPase and the membrane fluidity were determined. The n-alkanols exhibited an increased molar inhibition of the ATPase activity with an increase in the carbon chain length up to 1-octanol. 1-octanol and 1-decanol caused a biphasic effect on the ATPase activity depending on the alkanol concentration, whereas 1-dodecanol caused a stimulation of the ATPase activity. All alkanols studied caused an increased fluidity of the membrane ... /These/ results indicate that the effect of alkanols on the ATPase activity depends on changes in the border layer between the membrane and the surrounding medium and on a binding of the alkanols to the enzyme molecule ... The two-way effect of 1-octanol and 1-decanol and the stimulatory effect of 1-dodecanol indicate that more mechanisms are involved ... Changes in the membrane fluidity do not seem to be a prerequisite of the ATPase inhibition.

How do alcohols react in vivo?

The primary aliphatic alcohols undergo two general reactions in vivo, namely oxidation to carboxylic acids and direct conjugation with glucuronic acid. The first reaction proceeds with the intermediate formation of an aldehyde, and the carboxylic acid from the aldehyde may be either oxidized completely to carbon dioxide or excreted as such or combined with glucuronic acid as an ester glucuronide. The extent to which an alcohol undergoes the second reaction, i.e. direct conjugation to an ether glucuronide, appears to depend upon the speed of the first reaction. Alcohols which are rapidly oxidized form very little ether glucuronide unless given in high doses.

Is octanol a food additive?

1-Octanol is a food additive permitted for direct addition to food for human consumption as a synthetic flavoring substance and adjuvant in accordance with the following conditions: a) they are used in the minimum quantity required to produce their intended effect, and otherwise in accordance with all the principles of good manufacturing practice, and b) they consist of one or more of the following, used alone or in combination with flavoring substances and adjuvants generally recognized as safe in food, prior-sanctioned for such use, or regulated by an appropriate section in this part.

Does 1-octanol absorb sunlight?

Physical removal from air via precipitation has been shown to occur (4). 1-Octanol does not contain chromophores that absorb at wavelengths >290 nm (5) and, therefore, is not expected to be susceptible to direct photolysis by sunlight (SRC).

Why is smell important in organic chemistry?

In exploring organic chemistry, there are many different areas that the knowledge can be applied, and smell is one of the most interesting areas since humans innately link smells to memories and experiences.

What is the smell of esters?

One common group that possesses a distinct odor is esters that have a lower molecular weight. Many of these esters have a fruit-like or sweet smell, and therefore, they can be found in common natural foods. In addition, they can be utilized in synthetic foods or drinks or other products.

How does perfume work?

For perfumes, the smells are carefully layered and engineered, such that different smells unfold as time goes on. To create these layers, it is determined how fast certain chemicals evaporate from the skin, with stronger smells lasting the shortest time and baser smells lasting longer.

What is the chemical that makes pear oil?

For example, pear oil is a commonly found artificial flavor that is formed from a solution of isoamyl acetate in ethanol. Another industry that heavily utilizes chemistry in combination with smells is the perfume industry.

Overview

1-Octanol, also known as octan-1-ol, is the organic compound with the molecular formula CH3(CH2)7OH. It is a fatty alcohol. Many other isomers are also known generically as octanols. 1-Octanol is manufactured for the synthesis of esters for use in perfumes and flavorings. It has a pungent odor. Esters of octanol, such as octyl acetate, occur as components of essential oils. It is used to evaluate the lipophilicity of pharmaceutical products.

Preparation

Water/octanol partitioning

Properties and uses

See also