what does logopenic mean

by Joanie Waelchi Published 2 years ago Updated 2 years ago

The term Logopenic comes from a combination of two ancient Greek words: logo meaning speech and penic meaning 'lack of'. Progressive refers to the fact that the disease gets worse over time. Aphasia is a word that also refers to changes in a person's speech. LPA is one of three language based dementias.

What is logopenic progressive aphasia?

Summary Summary. Logopenic progressive aphasia (LPA) is a type of dementia characterized by language disturbance, including difficulty making or understanding speech (aphasia). It is a type of primary progressive aphasia (PPA). Affected individuals have slow, hesitant speech due to difficulty retrieving the correct words, names, or numbers.

What is logopenic dementia?

Logopenic dementia is an uncommon clinical variant of Alzheimer disease and is a subtype of primary progressive aphasia, which itself is a subtype of frontotemporal lobar degeneration (FTLD). It is important to note, that the terminology of, and classification, of these related conditions is evolving and thus variable across the literature 2,3.

What is logopenic variant PPA?

Logopenic Variant PPA FTD syndromes characterized predominantly by the gradual loss of the ability to speak, read, write and understand what others are saying fall under the category of primary progressive aphasia, or PPA. PPA is diagnosed when three criteria are met: There is a gradual impairment of language (not just speech).

What are the signs and symptoms of logopenic PPA?

Although patients with the logopenic variant of PPA are still able to produce speech, their speech rate may be significantly slowed due to word retrieval difficulty. Over time, they may experience the inability to retain lengthy information, causing problems with understanding complex verbal information.

What is Logopenic speech?

People with logopenic variant PPA (lvPPA, also known as PPA-L) have difficulty finding words when they are speaking. As a result, they may speak slowly and hesitate frequently as they search for the right word. Unlike people with semantic variant PPA, however, they are still able to recall the meanings of words.

What causes Logopenic aphasia?

What is the life expectancy for someone with PPA?

Many people with PPA eventually lose their language skills over many years, limiting their ability to communicate. Most people who have the condition live up to 12 years after their initial diagnosis.

What type of dementia causes aphasia?

Primary progressive aphasia is a type of frontotemporal dementia, a cluster of related disorders that results from the degeneration of the frontal or temporal lobes of the brain, which include brain tissue involved in speech and language.

Is Logopenic aphasia Alzheimer's?

The logopenic variant of PPA (lvPPA) is characterized by difficulties in single-word retrieval, repetition of sentences/phrases, presence of phonologic errors, left posterior perisylvian or parietal atrophy and typical association with the pathological finding of Alzheimer's disease (AD).

Does aphasia lead to dementia?

Primary progressive aphasia This is a rare type of dementia, where language is heavily affected. As it's a primary progressive condition, the symptoms get worse over time. Usually, the first problem people with primary progressive aphasia (PPA) notice is difficulty finding the right word or remembering somebody's name.

What causes death in PPA patients?

Although PPA itself is a life-shortening condition, people with PPA will often be affected by another illness, such as pneumonia. This is because PPA affects how the body copes with infection and with other physical problems. Pneumonia is the cause of death in up to two thirds of people with a dementia.

What are final stages of PPA?

Late-Stage Primary Progressive Aphasia In late-stage PPA, the gradual loss of speech and language will typically result in severely pronounced symptoms. Eventually, almost all patients with PPA lose their ability to speak, read, and write. Spoken language becomes incomprehensible.

Can you fully recover from aphasia?

Some people with aphasia recover completely without treatment. But for most people, some amount of aphasia typically remains. Treatments such as speech therapy can often help recover some speech and language functions over time, but many people continue to have problems communicating.

What stage of Alzheimer's is aphasia?

Diagnosis. Word-finding aphasia is a common symptom of early-stage Alzheimer's disease, but there are others. 4 Your doctor will ask about your loved one's symptoms and may want to speak with family members. Interestingly, aphasia affects a person's second language before it begins to affect their first language.

How serious is aphasia?

Because aphasia is often a sign of a serious problem, such as a stroke, seek emergency medical care if you or a loved one suddenly develop: Difficulty speaking. Trouble understanding speech. Difficulty with word recall.

Is aphasia part of dementia or Alzheimer's?

Primary progressive aphasia (PPA) is a type of dementia, caused by damage to parts of the brain that control our language, personality, emotions and behaviour.

What is the most common cause of aphasia?

stroke – the most common cause of aphasia. severe head injury. a brain tumour. progressive neurological conditions – conditions that cause the brain and nervous system to become damaged over time, such as dementia.

Is Logopenic aphasia hereditary?

LPA can be sporadic, familial or inherited. In sporadic cases the disease occurs out of the blue.

What can cause Wernicke's aphasia?

Wernicke's aphasia is caused by damage to your brain. It is usually on the left side....This aphasia results from loss of blood flow to your brain or other damage caused by:Stroke.Encephalitis, or brain inflammation.Head injury.Brain infection.

What is aphasia and its causes?

Aphasia is a disorder that affects how you communicate. It can impact your speech, as well as the way you write and understand both spoken and written language. Aphasia usually happens suddenly after a stroke or a head injury.

What is the name of the condition where you have trouble thinking of words?

Persons with logopenic variant primary progressive aphasia (lvPPA) have increasing trouble thinking of the words they want to say. As time goes on, people with lvPPA have more trouble getting the words out, and they eventually begin to speak slower and slower.

When do you start to see symptoms of LVPPA?

Most people with lvPPA start to have symptoms in their 50s, although some people have shown signs earlier or later.

What Causes lvPPA?

The cause of lvPPA is unknown. Scientists know that in lvPPA there is a large build-up of proteins called amyloid and tau within brain cells, which are the same proteins that build up in Alzheimer’s disease. These proteins occur normally, but we do not yet understand why they build up in large amounts. As more and more proteins form in brain cells, the cells lose their ability to function and eventually die. This causes the affected parts of the brain, most often the left posterior temporal cortex and inferior parietal lobe, to shrink.

How to help someone with LVPPA?

There are various ways to help a person with lvPPA. Speech therapy may help improve communication between people with lvPPA and others. Research has shown that physical exercise helps to enhance brain health and improves mood and general fitness.

Can a person with LVPPA lose the ability to understand words?

People with lvPPA generally do not lose the ability to understand words, as is the case in the semantic variant. Later in the disease, people with lvPPA may have such difficulty finding words that they might stop speaking completely. Difficulties with memory may develop or get worse, and reading and writing may become harder.

Entries with "logopenic"

logopenia: logopenia (English) Noun logopenia (uncountable) (pathology) logopenic progressive aphasia The Global Cognition, Frontal Lobe Dysfunction and Behavior Changes in Chinese Patients with…

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Which lobe is affected by logopenic dementia?

In contrast to FTLD, it is the more posterior part of the temporal lobe and parietal lobe, rather than the anterior temporal lobe and frontal lobe, which are affected. The temporoparietal distribution is a feature which echoes the fact that logopenic dementia is a variant of Alzheimer disease 1 .

Which lobes do logopenic dementia patients have hypometabolism in?

Patients with logopenic dementia demonstrate hypometabolism in the left temporal and parietal lobes 1 .

What is histopathologic evidence?

histopathologic evidence of a specific neurodegenerative pathology (e.g. AD, FTLD-tau, FTLD-TDP, other) or presence of a known pathogenic mutation

Is logopenic dementia aphasia?

Generally logopenic dementia is considered one of three subtypes of primary progressive aphasia, along with semantic dementia and progressive non-fluent aphasia 1-3 .

Diagnosis

Doctors will consider a diagnosis of lvPPA based on the following symptoms:

Treatment, Management, and What to Expect

As with all forms of FTD, there is no cure for PPA, and in most cases its progression cannot be slowed.

Genetics

Logopenic PPA can be sporadic, familial or hereditary. The majority of cases are not hereditary.

Pathology

In contrast to other forms of PPA, the brains of many – but not all – people with lvPPA exhibit pathological features similar to those seen in Alzheimer’s disease, such as neurofibrillary tangles or imaging evidence of amyloid deposits.

Who gets Logopenic Progressive Aphasia? (Age and Sex Distribution)

Logopenic Progressive Aphasia is a rare, congenital disorder. The presentation of symptoms typically occur in adulthood

What are the Risk Factors for Logopenic Progressive Aphasia? (Predisposing Factors)

A positive family history may be an important risk factor, since Logopenic Progressive Aphasia can be reportedly an inherited condition

How is Logopenic Progressive Aphasia Diagnosed?

Logopenic Progressive Aphasia is diagnosed on the basis of the following information:

What are the possible Complications of Logopenic Progressive Aphasia?

Progressive worsening of the condition, with trouble understanding long or complex verbal information (due to problems holding onto lengthy information that an affected individual hears)

How is Logopenic Progressive Aphasia Treated?

The treatment methods for Logopenic Progressive Aphasia may include the following, either singly or in combination

How can Logopenic Progressive Aphasia be Prevented?

The exact cause of Logopenic Progressive Aphasia is not known, and therefore, no methods or guidelines are available for its prevention

Additional and Relevant Useful Information for Logopenic Progressive Aphasia

The following DoveMed website link is a useful resource for additional information:

What is the cause of logopenic progressive aphasia?

Logopenic progressive aphasia is caused by damage to segregated brain regions, specifically the inferior parietal lobe and superior temporal regions. Difficulties in naming are produced from the thinning of the inferior parietal lobe.

What is LPA in medical terms?

Logopenic progressive aphasia ( LPA) is a variant of primary progressive aphasia. It is defined clinically by impairments in naming and sentence repetition. It is similar to conduction aphasia and is associated with atrophy to the left posterior temporal cortex and inferior parietal lobule. It is suspected that an atypical form of Alzheimer's disease is the most common cause of logopenic progressive aphasia.

Is logopenic variant worse than other aphasia?

Studies have shown that patients with the logopenic variant perform significantly worse on tests of calculation than other primary progressive aphasia patients.