What does ProHeart 6 cover? ProHeart 6, an injectable prescription parasiticide, is the only U.S. Food and Drug Administration (FDA)-approved injectable heartworm disease preventative that protects dogs for six months against heartworm disease caused by Dirofilaria immitis
Dirofilaria immitis
Dirofilaria immitis, the heartworm or dog heartworm, is a parasitic roundworm that is a type of filarial worm, a small thread-like worm, that causes dirofilariasis. It is spread from host to host through the bites of mosquitoes. The definitive host is the dog, but it can also infect cats, wolves…
What is ProHeart 6?
Feb 24, 2020 · What does ProHeart 6 cover? ProHeart 6 , an injectable prescription parasiticide, is the only U.S. Food and Drug Administration (FDA)-approved injectable heartworm disease preventative that protects dogs for six months against heartworm disease caused by Dirofilaria immitis; it also treats preexisting infections with common hookworms (Ancylostoma
What is ProHeart 6 heartworm medicine for dogs?
Nov 01, 2018 · ProHeart 6 contains a drug called moxidectin, which paralyzes and kills heartworm larvae. ProHeart 6 also kills hookworms, which live in the intestine. The moxidectin is contained within tiny structures called microspheres. When ProHeart 6 is injected, these microspheres slowly dissolve and release moxidectin.
Can you give ProHeart 6 to a puppy?
What is ProHeart 6? ProHeart 6 is a medication that prevents heartworm disease in dogs 6 months of age and older. Your veterinarian gives it to your dog via an injection and it protects your dog from developing heartworm disease for 6 full months. ProHeart 6 also treats common hookworm infections your dog may have at the time of injection.
What's new at ProHeart 12?
ProHeart 6 provides 6 months of heartworm disease prevention in just 1 shot. The active ingredient, moxidectin, is contained in slow-dissolving microspheres that are stored in your dog’s fat-storing connective tissue (a.k.a. adipose tissue).
Does ProHeart 6 prevent intestinal parasites?
ProHeart 6 does not offer protection against other common intestinal parasites like whipworm, roundworm or hookworm, although it can be used as a treatment for hookworms present at the time of administration.Sep 30, 2013
What does ProHeart 6 Treat?
ProHeart 6 is indicated for use in dogs six months of age and older for the prevention of heartworm disease caused by Dirofilaria immitis. ProHeart 6 is indicated for the treatment of existing larval and adult hookworm (Ancylostoma caninum and Uncinaria stenocephala) infections.
Does ProHeart 6 injection prevent fleas?
ProHeart 6 is approved for dogs 6 months of age or older and ProHeart 12 for dogs 12 months of age or older. ProHeart also protects against Hookworms (a common intestinal parasite). Since it does not protect against fleas or ticks, a flea and tick preventative, such as Nexgard or Bravecto, must be given as well.Jan 29, 2021
Does ProHeart 6 protect against hookworms?
Proheart6 is a twice-yearly injectable heartworm disease preventative. It's the only heartworm product that provides six months of continuous protection against heartworm disease with a single dose. It also will treat common hookworm infections that are present at the time of the injection.Oct 29, 2018
What is the safest heartworm medicine for dogs?
The two most common (and generally considered safe) heartworm preventative ingredients used today are ivermectin (used in Heartgard by Merial, and other products) and milbemycin oxime (used in Interceptor by Novartis).Jan 24, 2006
Does ProHeart protect against roundworms?
Unlike most monthly chewable preventatives, ProHeart 6 does not protect against common intestinal parasites like whipworms, roundworms, and hookworms (though it does treat hookworm infections).
Can you give Simparica trio with proheart?
We will also be carrying Simparica that can be combined with Proheart to offer flea/tick and heartworm protection for those who do not wish to continue flea/tick protection in the winter months.Nov 4, 2020
Does proheart cover flea and tick?
1 Injection of Proheart 12 Simparica is a oral chewable flea and tick prevention. When given monthly, it will provide your dog with year round flea and tick coverage.
What are monthly preventatives for cats?
The current recommendation from AHS and CAPC is for cats to take simple anti-vector illness medicine every month. Revolution is a topical parasite preventative that protects cats from parasites and fleas, and also kills flea eggs and nits.Dec 31, 2020
Is ProHeart better than Heartgard?
Conclusions. A single administration of ProHeart 12 was 98–100% effective in preventing the development of the ML-resistant JYD-34 heartworm strain and was significantly better than multiple consecutive monthly doses of either Heartgard Plus or Interceptor Plus in both studies.Apr 26, 2021
Does ProHeart 12 have ivermectin?
ProHeart 12 has also been found to be safe for dogs that are sensitive to ivermectin, which is a common ingredient in oral heartworm preventatives. Talk with your veterinarian to see if your dog is a good candidate.Sep 20, 2019
Do they still make Heartgard for dogs?
These tablets are used to prevent heartworm disease and treat and control hookworms and roundworms. Treats dogs 6 weeks in age and older weighing 1 to 25 pounds....For Pet Weight Min.*Protect your dog from potentially deadly heartworm disease*Delicious beef-flavored chewable is easy to administer1 more row
What is ProHeart 6?
ProHeart 6 Indications. ProHeart 6 is indicated for use in dogs six months of age and older for the prevention of heartworm disease caused by Dirofilaria immitis. ProHeart 6 is indicated for the treatment of existing larval and adult hookworm (Ancylostoma caninum and Uncinaria stenocephala) infections.
When to give ProHeart 6?
When replacing another heartworm preventive product, ProHeart 6 should be given within one month of the last dose of the former medication. ProHeart 6 eliminates the larval and adult stages of A. caninum and U. stenocephala present at the time of treatment.
How long does it take for moxidectin to be absorbed into blood after Pro Heart 6?
Following injection with ProHeart 6, peak moxidectin blood levels will be observed approximately 7-14 days after treatment. At the end of the six month dosing interval, residual drug concentrations are negligible.
How many times should I give my dog Pro Heart 6?
ProHeart 6 administered at 3 times the recommended dose did not adversely affect the reproductive performance of male or female dogs. ProHeart 6 administered up to 5 times the recommended dose in 7-8 month old puppies did not cause any systemic adverse effects.
How to contact Zoetis about Pro Heart 6?
For a copy of the Safety Data Sheet (SDS) or to report suspected adverse reactions, contact Zoetis Inc. at 1-888-963-8471. For additional information about adverse drug experience reporting for animal drugs, contact FDA at 1-888-FDA-VETS or ...
Can Pro Heart 6 kill a dog?
ProHeart 6 should be administered with caution in dog s with pre-existing allergic disease, including food allergy, atopy, and flea allergy dermatitis. In some cases, anaphylactic reactions have resulted in liver disease and death.
How old is a dog to take Pro Heart 6?
IMPORTANT SAFETY INFORMATION: Use ProHeart 6 in dogs 6 months of age or older and ProHeart 12 in dogs 12 months of age or older. Do not administer to dogs that are sick, debilitated, underweight, have a history of weight loss, or to those previously found to be hypersensitive to the drug.
What is Pro Heart 12?
*ProHeart 12 is indicated for the treatment of existing larval and adult hookworm ( Ancylostoma caninum and Uncinaria stenocephala) infections.
Can Proheart 12 cause diarrhea?
Yes. In fact, in a clinical study with client-owned dogs, ProHeart 12 had a similar adverse event profile to Heartgard Plus. The most common side effects were vomiting, diarrhea, and lethargy. As with all medications, adverse events are possible.
Is ProHeart 12 safe for dogs?
In three well-controlled studies, ProHeart 12: 2. Was 100% effective against heartworm disease* in dogs. Was demonstrated to be safe for most types of dogs over 12 months, including: Reproducing dogs. Collies sensitive to ivermectin—a common ingredient in monthly heartworm products.
Can a mosquito bite cause heartworms in dogs?
A single bite from an infected mosquito can put your dog at risk for developing heartworm disease. An infected mosquito bites your dog, infecting your dog with heartworm larvae. The heartworms then mature inside your dog, living in major vessels around the heart and even sometimes inside the heart itself.
Heartworm disease is a serious, potentially fatal illness
That’s no joke! Cases have been diagnosed in all 50 states 4 —so it’s important to protect your dog no matter where you live.
How do dogs get infected?
The short answer: mosquitoes. A single bite from an infected mosquito can put your dog at risk for developing heartworm disease.
Heartworm disease is a risk no matter where you live
The severity of heartworm incidence as shown in this map is based on the average number of cases per reporting clinic. Some remote regions of the United States lack veterinary clinics, therefore we have no reported cases from these areas.
How often is Proheart 6 given?
Proheart is an INJECTABLE heartworm prevention that is only given every 6 months! …”. Racine Veterinary Hospital writes: “Proheart 6 is an injectable heartworm prevention. 1 injection lasts 6 months, which means you don’t have to worry about missing a dose…”. Eastpoint Vet writes:
What is ProHeart 12?
The FDA just announced the approval of a ProHeart 12, a brand new heartworm preventive for dogs . Yippee!
When did ProHeart 6 come out?
You need to know more about it before you run to your vet for a prescription. This drug is a stronger version of ProHeart 6. That’s a drug that came out in 2000, offering 6 months’ heartworm prevention . But it was taken off the market in 2004 after many reports of adverse events (including deaths).
Does ProHeart 6 cause cancer?
Even the FDA found ProHeart 6 caused cancer. “The FDA Vet that pulled ProHeart 6 said that the company was aware of the risk of cancer. She said there were more adverse events with just ProHeart than every one of the heartworm preventions put together.”. But not all vets will tell you this ….
Does moxidectin kill worms?
The active ingredient, moxidectin, is used in tablet form to treat onchocerciasis (river blindness) in humans. The label for that drug says the drug doesn’t kill the adult worms that cause the disease …. Onchocerca volvulus. It just stops them from releasing microfilariae.
Who is Julia Henriques?
Julia Henriques. Julia Henriques is Managing Editor of Dogs Naturally Magazine. She's on the Board of Playing Again Sams (Wisconsin Samoyed Rescue) where she enjoys helping adopters and group members choose more natural health care options for their dogs.
Can heartworms cause coughing in dogs?
Urinary: elevated BUN, elevated creatinine, hematuria, polydipsia, polyuria and. cardiopulmonary signs such as coughing and dyspnea may occur in heartworm-positive dogs. In some cases, death has been reported as an outcome of the adverse events listed above.
Description
- ProHeart 6 (moxidectin) for extended-release injectable suspension consists of two separate vials: One vial contains 10% moxidectin sterile microspheres and the second vial contains a specifically formulated sterile vehicle for constitution with the microspheres. No other diluent should be used. A clear or translucent appearance of the vehicle is normal. Each mL of constitut…
Pharmacology
- Moxidectin is a semi-synthetic methoxime derivative of nemadectin which is a fermentation product of Streptomyces cyaneogriseussubspecies noncyanogenus. Moxidectin is a pentacyclic 16-membered lactone macrolide. Moxidectin has activity resulting in paralysis and death of affected parasites. The stage of the canine heartworm affected at the recommended dose rate …
Proheart 6 Indications
- ProHeart 6 is indicated for use in dogs six months of age and older for the prevention of heartworm disease caused by Dirofilaria immitis. ProHeart 6 is indicated for the treatment of existing larval and adult hookworm (Ancylostoma caninum and Uncinaria stenocephala)infections.
Proheart 6 Dosage and Administration
- Owners should be given the Client Information Sheet for ProHeart 6 to read before the drug is administered and should be advised to observe their dogs for potential drug adverse events including those described in the sheet. The Client Information Sheet is attached to this package insert and available online at http://www.proheart6.com/ for reprinting to provide to the owner. P…
Information For Dog Owners
- Always provide Client Information Sheet and review with owners before administering ProHeart 6. Owners should be advised of the potential for adverse reactions, including anaphylaxis, and be informed of the clinical signs associated with drug toxicity (see WARNINGS, PRECAUTIONS and ADVERSE REACTIONSsections.) Owners should be advised to contact their veterinarian immedi…
Human Warnings
- Not for human use. Keep this and all drugs out of the reach of children. May be slightly irritating to the eyes. May cause slight irritation to the upper respiratory tract if inhaled. May be harmful if swallowed. If contact with the eyes occurs, rinse thoroughly with water for 15 minutes and seek medical attention immediately. If accidental ingestion occurs, contact a Poison Control Center o…
Warnings
- ProHeart 6 should be administered with caution in dogs with pre-existing allergic disease, including food allergy, atopy, and flea allergy dermatitis. In some cases, anaphylactic reactions have resulted in liver disease and death. Anaphylactic and anaphylactoid reactions should be treated immediately with the same measures used to treat hypersensitivity reactions to vaccine…
Precautions
- Caution should be used when administering ProHeart 6 concurrently with vaccinations. Adverse reactions, including anaphylaxis, have been reported following the concomitant use of ProHeart 6 and vaccinations (see WARNINGS). Prior to administration of ProHeart 6, the health of the patient should be assessed by a thorough medical history, physical examination and diagnostic testing …
Adverse Reactions
- In field studies, the following adverse reactions were observed in dogs treated with ProHeart 6: anaphylaxis, vomiting, diarrhea (with and without blood), listlessness, weight loss, seizures, injection site pruritus, and elevated body temperature. Dogs with clinically significant weight loss (>10%) were more likely to experience a severe adverse reaction. In a laboratory effectiveness st…
Animal Safety
- General Safety: ProHeart 6 has been administered to a wide variety of healthy dogs six months of age and older, including a wide variety of breeds, pregnant and lactating females, breeding males, and ivermectin-sensitive collies. In clinical studies, two geriatric dogs with a history of weight loss after the initial ProHeart 6 injection died within a month of the second 6 month injection. A third …